CLC Genomics Server and CLC Genomics Workbench

NCI users have access to CLC Genomics Server and CLC Genomics Workbench now!

The CLC Genomics Workbench is the client software for the CLC Genomics Server. Investigators can run many of the tasks on the workbench with an easy option to submit longer running tasks to run on the Genomics Server. The Genomics Server not only provides a scalable computing solution for computationally demanding tasks like genome mapping and RNA-seq analysis but also manages access to filesystems and databases to support these bigger jobs. Features for both the Genomics Workbench and Genomics Server are described below.

CLC Genomics Workbench

CLC Genomics Workbench, for analyzing and visualizing Next Generation Sequencing data, incorporates cutting-edge technology and algorithms, while also supporting and integrating with the rest of your typical NGS workflow.

  • Read mapping of Sanger, 454, Illumina and SOLiD sequencing data
  • De novo assembly of genomes of any size (only limited by RAM available)
  • Color space mapping
  • Advanced visualization, scrolling, and zooming tools
  • SNP detection using advanced quality filtering
  • Support for multiplexing with DNA barcoding
  • RNA-seq including support for paired data and transcript-level expression
  • Small RNA analysis
  • Expression profiling by tags
  • EST library construction
  • Advanced visualization, scrolling, and zooming tools
  • Gene expression analysis
  • Chromatin immunoprecipitation sequencing (ChIP-seq) analysis
  • Peak finding and peak refinement
  • Graph and table of background distribution and the false discovery rate
  • Peak table and annotations

CLC Genomics Server

CLC Genomics Server is an advanced High-Throughput Sequencing focused three-tier solution offering secure, powerful, and flexible bioinformatics computing on a server-architecture located centrally in ABCC, NCI Frederick.

  • Read mapping of Sanger and High-Throughput Sequencing data
  • De novo assembly of Sanger and High-Throughput Sequencing data
  • SNP detection on whole genomes of any size
  • DIP detection on whole genomes of any size
  • ChIP-seq analysis
  • RNA-Seq analysis
  • Small RNA analysis
  • Trim Sequences

Click the Here to learn more about CLCBio (www.clcbio.com).

Company

Qiagen

Access Information

You must submit a request through “NCI at Your Service” to obtain access to CLC Software.