Geneious R11

 

Geneious is a DNA, RNA, and protein sequence alignment, assembly, and analysis software platform, integrating bioinformatic and molecular biology tools into a simple interface.

NGS Assembly

  • Import a wide range of formats
  • Extensive pre-processing
  • Reliable reference mapping
  • Flexible de novo assembly
  • Velvet, Maq, Bowtie on Geneious Server™

Visualizations

  • 3D structures
  • Sequences, alignments, assemblies
  • Annotations, SNPs, restriction sites
  • Phylogenetics trees
  • Dot plot, virtual gel
  • RNA secondary structure

Chromatogram Editing and Assembly

  • Chromatogram assembly of Sanger data
  • Import Sequencher data from.CAF file
  • Assemble by name
  • Call secondary peaks

Geneious Biocode LIMS

  • Manage sequences in 96/384 well plates
  • Import chromatograms & attach to plates
  • Bin and trim chromatograms
  • Verify Taxonomy vs Genbank
  • Genbank submission

Alignment

  • ClustalW (Greenbutton enabled)
  • MUSCLE and MAFFT alignment
  • Translation and profile alignment
  • MAUVE genome alignment

Phylogenetics

  • MrBayes (Greenbutton enabled)
  • PAUP* interface including ModelTest
  • NJ, UPGMA, and PhyML
  • Bootstrapping and consensus trees
  • Interactive tree viewing

Cloning

  • One-step multi-site Gateway Cloning
  • One-step insert fragment into vector
  • Virtual gel viewer
  • Restriction digest
  • Show non-cutting enzymes

Primer Design

  • PCR primers and probes with Primer3
  • Primers on alignments and assemblies
  • Built-in primer database
  • Test existing primers vs sequence
  • Sequencing & multiplex primers (coming soon)

Database Search

  • BLAST and custom BLAST search
  • Local search
  • Sequence search
  • Literature search
  • Automated search agents

Predict, Manipulate and Annotate

  • ORFs, repeats, CpG islands
  • SNPs, INDELs, low/high coverage
  • Protein secondary structure
  • Cleavage sites, transcription factors
  • Antigenic regions, Pfam domains

Access Information

You must submit a request through “NCI at Your Service” to obtain access to Geneious Pro Software.

Company

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