Frederick Sequencing and Genomic Core (FSGC)

The Frederick Sequencing and Genomics Core (FSGC) was established through the integration and consolidation of the former Sequencing Facility and the Genomics Technology Laboratory. The new FSGC eliminates redundancy and provides cutting edge sequencing technologies and assay development capabilities to the NCI. NGS services are made available to NIAID Division of Intramural Research (DIR) through a negotiated MOU.  This core is operated by Leidos Biomedical Research Inc. on behalf of NCI as part of the Frederick National Laboratory.

Next-generation Sequencing Production Group (previously Sequencing Facility)

The introduction of DNA sequencing instruments capable of producing millions of DNA sequence reads in a single run has profoundly altered the landscape of genetics and cancer biology. Complex questions can now be answered at previously unthinkable speeds and a fraction of their former cost. The NGS Production Group provides researchers access to the latest technologies, with consultation and Q&A services available throughout the design and execution of sequencing projects. The group is a CCR-dedicated lab open to all CCR Investigators. Dedicated capacity has also been established for NAID Investigators. 

Assay Development Group (previously Genomics Technology Lab) 

The Assay Development Group is an integrated, high-throughput molecular biology lab focused on the development of genetics and genomics assays, data analysis, and information management tools, in support of CCR Investigators. The group develops integrated strategies using multiple technology platforms that maximize the value of research or clinical samples and lead to the identification of pathways, genes, or gene products involved in the development of disease, as well as the assembly of genetic or expression profiles for the identification of prognostic and diagnostic indicators. The group specializes in the development of custom genomics assays for quantitation and identification of specific molecules in complex clinical samples with a specific interest in developing liquid biopsy assays.