CCR Collaborative Bioinformatics Resource (CCBR)

The CCR Collaborative Bioinformatics Resource (CCBR) is a centrally-funded resource group which provides a mechanism for CCR researchers to obtain many different types of bioinformatics assistance to further their research goals. The group has expertise in a broad range of bioinformatics topics, and as such, its goal is to provide a simplified central access point for CCR researchers. Requests for any type of Bioinformatics support should be through the CCBR Project Submission Form.

Types of Collaborative Expertise:

• Next Generation Sequence (NGS) data analysis (RNAseq, scRNAseq, ATAC-seq, ChIP-seq, WES, WGS, CRISPR-seq, Cut & Run, etc.)
• Data mining, statistical and mathematical analysis using multiple approaches
• Pathway mapping and biological interpretation
• Multi-experiment data integration and correlation
• miRNA and array CGH analysis
• SNP and base calling
• Data Mining/Management/Integration
• Immune Repertoire/VDJ/Antibody Sequencing
• Long-read sequencing technologies
• Metagenomics
• Methylation Sequencing/Array
• Proteomics
• Spatial transcriptomics
• Microarray analysis across multiple platforms and custom arrays

User-Friendly, Automated Bioinformatics Workflows:

The NIH Integrated Data Analysis Platform (NIDAP), is a cloud-based, collaborative data aggregation and analysis platform. The platform hosts user-friendly bioinformatics workflows and other component analysis and visualization tools that have been created and maintained by the NCI developer community based on open-source tools. These workflows and other tools can be made immediately available to biologist end-users across the Institute. Robust controls allow users to work individually or collaboratively with PII/PHI while also maintaining proper security and ownership over their datasets. Workflows are available for analysis of bulk and single cell RNAseq data and data from Nanostring's GeoMx Digital Spatial Profiling (DSP) platform.

New users can access NIDAP by registering at http://nidap.nih.gov.