NATIONAL CANCER INSTITUTE - CANCER.GOV

Contact Information


Primary Contact

Uma Shankavaram
Senior Associate Scientist

Location

10 center dr
Bethesda
Bethesda, Maryland 20854

Additional Contacts

Kevin Camphausen
Branch Chief

Overview

Radiation Oncology Branch is part of CCR. Bioinformatics core is a collaborative resource to support ROB branch and provide service to ROB investigators from NCI and other Institutes access to new technologies, bioinformatics, statistical analysis related to genetics/genomics, and offers access to in-house built software tools.

Bioinformatics analysis: work with research scientists to provide consulting prior to experiments, analysis of high-throughput sequencing, gene expression, metabolomics, proteomics, and other biological data to identify:

  • prognostic biomarkers
  • transcription factor analysis
  • gene set enrichment analysis
  • prediction models
  • clinical genomics
  • meta-analysis

In-house application development: develop applications to enhance research through web applications for data analysis, databases, visualization, and custom analysis tools:

User Guidelines

Open to all NIH investigators. Collaboration on a case-by-case basis on projects of mutual interest after initial consultation. 

Publications

  • A phase 1 dose escalation trial of re-irradiation for patients with recurrent glioblastoma Peter Mathen, Andra V Krauze, Lindsay Rowe, Huma Chaudhry, Megan Mackey, Theresa Cooley-Zgela, Erich Huang, Uma Shankavaram, Chris Zalewski, Joseph Snow, Martha Quezado, Jing Wu, DeeDee Smart, Kevin Camphausen 2026, Practical Radiation Oncology - Article
  • Radiogenomic Profiling of Prostate Tumors prior to External Beam Radiotherapy Converges on a Transcriptomic Signature of TGF-u03b2 Activity Driving Tumor Recurrence Anson T. Ku, Uma Shankavaram, Shana Y. Trostel, Hong Zhang, Sumeyra Kartal, Houssein A. Sater, Stephanie A. Harmon, Nicole V. Carrabba, Yang Liu, Hyunnam Ryu, James A. Proudfoot, Boon Hao Hong, Bradford J. Wood, Peter A. Pinto, Peter L. Choyke, Mack Roach, Howard M. Sandler, Stephanie L. Pugh, Kenneth L. Zeitzer, Lucas C. Mendez, Nirav S. Kapadia, William A. Hall, Anand B. Desai, Radka S. Stoyanova, Alan Pollack, Elai Davicioni, Melvin L.K. Chua, Baris Turkbey, Adam G. Sowalsky, Deborah E. Citrin 2025, Clinical Cancer Research - Article
  • Multicentered Biospecimen Analyses after 4 Gy Sublethal Total Body Irradiation in Rhesus Macaques J. Tyson McDonald, Claude J. Rogers, Denise Nishita, Shanaz A. Ghandhi, Alexandra Taraboletti, Shad R. Morton, Igor Shuryak, James Bakke, Janet Gahagan, Evan L. Pannkuk, Simon Authier, Molykutty J. Aryankalayil, Sunita Chopra, Mary Sproull, Uma Shankavaram, Kevin Camphausen, Guy Garty, Sally A. Amundson, David J. Brenner, Helen C. Turner, George W. Schaaf, John D. Olson, J. Mark Cline, Naresh Menon, Evagelia C. Laiakis, Albert J. Fornace, Polly Y. Chang 2025, Radiation Research - Article
  • The EGFR Pathway as a Potential Therapeutic Target for Modulation of Radiation-induced Liver Injury Satoshi Omiya, Juan Dalo, Yuki Ueda, Uma Shankavaram, Elisa Baldelli, Valerie Calvert, Michelle Bylicky, Emanuel F. Petricoin, Molykutty J. Aryankalayil 2025, Radiation Research - Article

Keywords

CCR Radiation Oncology Branch Bioinformatics CoreStRAPbioinformaticsdata analysisgene expresison analysisglioblastoma bio discovery portalhigh throughput sequencing analysismetabolomics analysisproteomics analysissoftwarestatistical analysisstress response array profilier