Single Cell Analysis Facility (SCAF)

The rapid advancement of single-cell technology has provided new powerful tools to answer many biological questions, such as identifying new or rare cell populations and characterizing the complexities of tumor heterogeneity.  Realizing the great potential of single-cell technology in cancer research, the CCR has established a new Single Cell Analysis Facility (SCAF), with a presence at the Frederick ATRF and the Bethesda main campus.

The SCAF will be composed of and supported by integrated resources and expertise from the CCR Sequencing Facility, CCR Genomics Technology Lab, CCR Genomics Core in Building 37, CCR Collaborative Protein Technology Resource in Building 37, and the CCR Collaborative Bioinformatics Resource. This will provide the broadest range of project support from consultation on experimental design sequencing and data analysis.

The SCAF will provide the most advanced single-cell genomics technologies to CCR investigators, including many established platforms, such as:

Emerging, technologies will include:

These technologies will give CCR-investigators the options for single cells studies, ranging from a few cells to hundreds of thousands of cells, and from single cell genomic assays such as RNA-seq to single cell protein quantification.  Both locations will have dedicated bioinformatics staff to help you perform preliminary analysis and deliver the data in a format that will enable to focus on your biological questions.

For further bioinformatics assistance, CCBR bioinformatics staff will be able to work with individual labs on the training of relevant analysis software or in-depth analysis consultation.

For general information about single-cell genomics technologies available to CCR, please contact Dr. Mike Kelly For general information and project consultation using the CODEX technology, please contact Dr. Noemi Kedei

To initiate a project consultation or schedule an experiment with our experts, please contact:

SCAF Bethesda Contact:
Dr. Mike Kelly
SCAF Frederick-ATRF Contact:
Dr. Monika Mehta
SCAF Bioinformatics Contact:
Yongmei Zhao
CCBR Bioinformatics Contact:
Dr. Maggie Cam