DTP’s Natural Products Repository is the world’s largest storehouse of natural products. It houses close to >200,000 extracts from samples of more than 70,000 plants and >20,000 marine organisms collected from more than 29 countries, plus extracts of diverse bacteria and fungi. In addition, the NCI Natural Products Repository also includes pre-fractionated natural products extracts created through the NCI Program for Natural Products Discovery. The pre-fractionated extract library has 500,000 partially-purified plated fractions, created from NPB crude extracts, available for screening. The Natural Products Repository, administered by the Natural Products Branch, provides extramural researchers with natural products extracts for testing against any human disease.