Contact Information

Primary Contact

Barry O’Keefe, Ph.D.


1050 Boyles Street
Frederick, MD 21702


DTP’s Natural Products Repository is the world’s largest storehouse of natural products. It houses close to >200,000 extracts from samples of more than 70,000 plants and >20,000 marine organisms collected from more than 29 countries, plus extracts of diverse bacteria and fungi. In addition, the NCI Natural Products Repository also includes pre-fractionated natural products extracts created through the NCI Program for Natural Products Discovery. The pre-fractionated extract library has 500,000 partially-purified plated fractions, created from NPB crude extracts, available for screening. The Natural Products Repository, administered by the Natural Products Branch, provides extramural researchers with natural products extracts for testing against any human disease.

List of Resources

  • ~80,000 plant samples collected in Africa and Madagascar, Central and South America, and Southeast Asia through contracts with the Missouri Botanical Garden, the New York Botanical Garden, and the University of Illinois at Chicago, assisted by the Arnold Arboretum of Harvard University and the Bishop Museum in Honolulu.
  • ~20,000 marine invertebrates and marine algae collected, mainly from the Indo-Pacific region, through contracts with the Harbor Branch Oceanographic Institute, the Australian Institute of Marine Science, the University of Canterbury, New Zealand, and the Coral Reef Research Foundation. In addition,
  • ~24,000 microbes accrued through contract with the University of Oklahoma Citizen Science Program.

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