NATIONAL CANCER INSTITUTE - CANCER.GOV

Contact Information


Primary Contact

Tristan Sissung
Facility Head

Location

Building 10, Room 5A01
Bethesda, MD 20892

Overview

The Pharmacogenetics Core is responsible for correlating outcome observations (toxicity, efficacy, survival, PK/PD) with genetic variants (germline or somatic) to identify key genetic determinants and biomarkers that predict response to specific treatments. We also evaluate the impact of genetic variants on drug metabolism, transport, and molecular targets that influence drug resistance or contribute to inter-individual variation in therapeutic outcomes.

User Guidelines

The Pharmacogenetics Core is open to all NCI intramural clinical investigators.

Keywords

bioanalysisnci-core