8560 Progress DriveUnited States Frederick, Maryland 21702
Overview
The Protein Expression Laboratory produces proteins to help CCR investigators achieve their research goals with the lowest possible cost in the shortest time. PEL is operated by Leidos Biomedical Research Inc. on behalf of NCI as part of the Frederick National Laboratory.
Established Technologies
Clone construction for protein expression
Expression in microbial, insect, and mammalian cells
Small-scale parallel expression and purification testing
Protein purification from micrograms to grams
User Guidelines
PEL services are available to all CCR investigators. To request services from this CCR-dedicated core facility, you must submit your requisition through NAS. Excess capacity can be made available to other NCI Investigators on a case-by-case basis.
Keywords
E. coliInsectSTRaffinity tag purificationbaculoviruscell culturecell line authenticationclone constructioncloningexpressionProteins and Proteomicsmammalianmutagenesisnci-coreprotein expressionprotein expression labprotein purificationqPCRshort tandem repeatyeast