Core
Collaborative
NCI Collaborative Protein Technology Resource - Mass Spectrometry
Bethesda, MD
Services Offered
Training Opportunities
The Mass Spectrometry Unit of the Collaborative Protein Technology Resource uses mass spectrometry for the study of proteins. We perform collaborative experiments with CCR researchers in areas such as: interactomes, quantitative global proteome analyses, and identification of sites of post-translational modification. In addition, we perform structural proteomics analyses. Finally, we also have an ICP-MS for analysis of inorganic atoms. Contact Details Manager: Lisa Jenkins, PhD Phone: 240.760.7209 Email: lisa.jenkins@nih.gov Instrumentation Thermo Explor… [learn more]
Core
Collaborative
NCI Collaborative Protein Technology Resource - Nanoscale Protein Analysis
Bethesda, MD
Services Offered
Training Opportunities
The Nanoscale Protein Analysis Section of the CCR Collaborative Protein Technology Resource (CPTR) provides expertise and service in state-of-the-art protein analysis technologies to advance CCR research in basic discovery and translation/clinical studies. Applications include: Quantitative profiling of cell signaling and post-translational modification Measurement of cytokine, metabolite and serum/plasma markers Identification and validation of biomarkers & therapeutic targets Assessment of on‐ and off‐target drug activity and pharmacodynamic evaluation Study of tumor microenviron… [learn more]
Core
NCI Protein Characterization Laboratory (PCL)
Frederick, MD
DescriptionProtein Characterization Laboratory (PCL) offers various technologies to CCR investigators to characterize proteins and metabolites. The laboratory develops and applies state-of-the-art analytical technologies, primarily mass spectrometry, liquid chromatography, and Surface Plasmon Resonance (SPR), to advance the understanding of cellular function at the protein, proteomics, metabolite and metabolomic levels.PCL engages in both short and long-term collaborations based on the need of each project. PCL is operated by Leidos Biomedical Research Inc. on behalf of NCI as part of … [learn more]
Core
The Protein Expression Laboratory
Frederick, Maryland
Services Offered
The Protein Expression Laboratory produces proteins to help CCR investigators achieve their research goals with the lowest possible cost in the shortest time. PEL is operated by Leidos Biomedical Research Inc. on behalf of NCI as part of the Frederick National Laboratory. Contact Details Laboratory Director: Dom Esposito, PhD Phone: 301-846-7376 Email: espositod@mail.nih.gov Address: ATRF, 8560 Progress Drive, Frederick, MD, 21701 Group Leader, Protein Production: Jane Jones Phone: 301-846-1201 Email: jonesj4@mail.nih.gov Address: ATRF, 8560 Progress Drive, F… [learn more]