NATIONAL CANCER INSTITUTE - CANCER.GOV

Contact Information


Primary Contact

Brian Luke
Sr. Principal Computational Scientist

Location

Building 1043
NCI-Frederick
Frederick, MD 21702

Additional Contacts

Alexander Mitrophanov
Sr. Statistican
Duncan Donohue
Sr. Data Scientist

Overview

The centrally funded Statistics team within the Advanced Biomedical Computational Science group at the Frederick National Lab provides statistical consultation and data analysis support for NCI laboratories. We have broad-range expertise in biomedically relevant areas of applied and computational statistics, as well as related subjects. The team can help with both advanced and standard statistical analyses. These include data-sample comparisons (such as pairwise comparisons and ANOVA), linear or nonlinear regression, linear or nonlinear mixed-effects modeling, survival analysis, power and sample size calculations, and biological network analysis. The team collaborates with NCI investigators and helps with experimental design, biological interpretation of statistical analysis results, and publications. Our people have extensive knowledge and experience in statistics, data science, applied mathematics, quantum chemistry, chemical reaction modeling, protein folding and interactions, custom programming, and computational systems biology. 

Services include:

  • Inferential Statistical Analysis and Hypothesis Testing
  • Mixed and Random Effects Hierarchical Modeling Analyses
  • Bioinformatics, Microarray, and Proteomics Analyses
  • Repeated Measures Analysis, Longitudinal Regression, and Modeling
  • Survival, Time-To-Event, and Cox Proportional Hazards Regression Analyses
  • Linear and Nonlinear Regression Analyses, Analysis of Variance (ANOVA) and Covariance (ANCOVA)
  • Categorical Data Analysis, Loglinear, Logistic, and Poisson Regression Analysis
  • Pharmacokinetics, Enzyme Kinetics, and Compartmental Modeling
  • Preparation of Manuscripts, Technical Documents, and Reports

User Guidelines

Services are available to FNLCR, NCI, NIH and associated investigators. To submit a consultation and assistance request, please contact Dr. Brian Luke at brian.luke@nih.gov or submit a request (https://abcs-amp.nih.gov/project/request/ABCS/; please note that you must be logged on to the NIH network for access).

Keywords

Analysis of Variance (ANOVA)BioinformaticsCategorical Data AnalysisCompartmental ModelingCovariance (ANCOVA)Cox Proportional Hazards Regression AnalysesEnzyme KineticsHierarchical Modeling AnalysesHypothesis TestingInferential Statistical AnalysisLinear and Nonlinear Regression AnalysesLogistic and Poisson Regression AnalysisLoglinearLongitudinal RegressionMicroarrayPharmacokineticsRepeated Measures AnalysisSurvivalTime-To-EventBioinformatics Biostatistics and Computingnci-coreproteomics Analyses