Radiation Oncology Branch is part of CCR. Bioinformatics core is a collaborative resource to support ROB branch and provide service to ROB investigators from NCI and other Institutes access to new technologies, bioinformatics, statistical analysis related to genetics/genomics, and offers access to in-house built software tools. Bioinformatics analysis: work with research scientists to provide consulting prior to experiments, analysis of high-throughput sequencing, gene expression, metabolomics, proteomics and other biological data to identify:prognostic biomarkerstranscription factor an… [learn more]

The CCR Collaborative Bioinformatics Resource (CCBR) is a centrally-funded resource group which provides a mechanism for CCR researchers to obtain many different types of bioinformatics assistance to further their research goals. The group has expertise in a broad range of bioinformatics topics, and as such, its goal is to provide a simplified central access point for CCR researchers. Requests for any type of Bioinformatics support should be through the CCBR Project Submission Form. Types of Collaborative Expertise: Next Generation Sequence (NGS) data analysis (RNAseq, scRNAseq, ATAC-seq,… [learn more]

Established TechnologiesCellMiner – Comprehensive molecular data on the NCI-60 cancer cell lines, including i) multiple microarray platforms measuring gene expression, ii) gene transcript level z score determination from 5 microarray platforms, iii) aCGH DNA copy number, iv) microRNA expression and v) SNP status, vi) Pattern comparison between transcript expression, microRNA expression, and drug activity for any input pattern of interest to the user vii) access to exome sequencing for all genes in the NCI-60 cell line and viii) Drug activity z score provides activity levels for 22,257 co… [learn more]

The Statistical Consulting & Scientific Programming Group provides a wide array of statistical-consulting services to the scientific community at the NCI and the Frederick National Laboratory for Cancer Research (FNLCR). The consulting statisticians collaborate with scientists and investigators, perform statistical analyses, provide technical reports, and prepare manuscripts for publication in scientific journals. Statistical consulting services are provided free of charge to the NCI and Contractor staff. The group includes three Ph.D.-level senior analysts, who are supported by programmer… [learn more]