Metabolomics

CCR Metabolomics Resource specializes in metabolomics using liquid and gas chromatography linked to mass spectrometers as analytical platforms is being actively used to find biomarkers for diseases including diabetes and carcinogenesis. This technology is ideally suited for the study the metabolism, toxicity and carcinogenicity of drugs and other chemicals. This technology can be engaged to find biomarkers for drug efficacy and toxicity. Metabolomics not only offers promise in the translational biomarker research but can also be used to understand mechanisms of toxicity and carcinogenicity… [learn more]

Protein Characterization Laboratory (PCL) offers various technologies to CCR investigators to characterize proteins and metabolites. The laboratory develops and applies state-of-the-art analytical technologies, primarily mass spectrometry, liquid chromatography, and Surface Plasmon Resonance (SPR), to advance the understanding of cellular function at the protein, proteomics, metabolite, and metabolomic levels. PCL engages in both short and long-term collaborations based on the need of each project. PCL is operated by Leidos Biomedical Research Inc. on behalf of NCI as part of the Frederick Nat… [learn more]