Pharmacology

The Biopharmaceutical Development Program (BDP) provides resources for the development of investigational biological agents. The BDP supports feasibility through development and Phase I/II cGMP manufacturing plus regulatory documentation. BDP is a DCTD-dedicated facility, but projects outside of DCTD can be considered on a case-by-case basis. If you are interested in collaborating with us, please submit a consultation request at: https://next.cancer.gov/experimentalTherapeutics/form.htm or contact the BDP directly: https://frederick.cancer.gov/Science/Bdp/contacts.aspx Contacting Thi… [learn more]

Thousands of molecular targets have been measured in the NCI panel of 60 human tumor cell lines. Measurements include protein levels, RNA measurements, mutation status and enzyme activity levels. You can choose to search for a target of interest, or you may browse through a list of targets. Follow the links for a target to retrieve the 60 cell line data (either text or graphical), to run COMPARE (find Targets or Compounds whose patterns correlate with a Target of interest) and to link to various databases with information (function, sequences, disease associations) about the target. To co… [learn more]