Pharmacology

The Biopharmaceutical Development Program (BDP) provides resources for the development of investigational biological agents. The BDP supports feasibility through development and Phase I/II cGMP manufacturing plus regulatory documentation.The BDP was established in 1993. We support the development of monoclonal antibodies, recombinant proteins, therapeutic peptides, and DNA vaccines, virus therapeutics and vaccines, gene therapy products, and other biological agents. Since its inception, BDP has completed more than 100 projects. The program has released over 220 lots of different products since… [learn more]

Thousands of molecular targets have been measured in the NCI panel of 60 human tumor cell lines. Measurements include protein levels, RNA measurements, mutation status and enzyme activity levels. You can choose to search for a target of interest, or you may browse through a list of targets. Follow the links for a target to retrieve the 60 cell line data (either text or graphical), to run COMPARE (find Targets or Compounds whose patterns correlate with a Target of interest) and to link to various databases with information (function, sequences, disease associations) about the target. To co… [learn more]