NATIONAL CANCER INSTITUTE - CANCER.GOV

Contact Information


Primary Contact

Parirokh “Roackie” Awasthi
Director

Location

Building 469, Room 205
1050 Boyle Street
Frederick, MD 21702

Overview

The Transgenic Mouse Model Laboratory (TMML) provides assistance to the scientific community with the generation of genetically engineered mice (GEM), offering a complete array of services aimed at the successful generation of transgenic and gene-targeted mice, and their expansion and cryopreservation.

Capabilities
  • Transgenic Mouse Production
  • Microinjection services
  • GEMM production utilizing CRISPR/Cas Technology
  • Cryopreservation
  • Reconstitution from Cryopreserved Germplasm
  • Strain Rescue
  • Colony Expansion by In-Vitro Fertilization (IVF)
  • Rederivation to SPF Health status

User Guidelines

To request MMC services from this CCR core facility, you must submit your requisition through NAS.

Keywords

Animal ResourcesCRISPR/cas9CryoCryopreservationCytoplasmic MicroinjectionEmbryoGEMMGenetically EngineeredIn-Vitro FertilizationIVFMouse ModelPronuclear MicroinjectionRecoveryRederivation