Frederick, MD
Collaborative
The Biopharmaceutical Development Program (BDP) provides resources for the development of investigational biological agents. The BDP supports feasibility through development and Phase I/II cGMP manufacturing plus regulatory documentation. The BDP was established in 1993. We Read More...
Rockville, MD
Collaborative
We are a bioinformatics team within the Center for Biomedical Informatics and Information Technology’s (CBIIT’s) Cancer Informatics Branch (CIB)—soon to be referred to as the Informatics and Data Science (IDS) Program. Headed Read More...
Bethesda, MD
Collaborative
The Mass Spectrometry Unit of the Collaborative Protein Technology Resource uses mass spectrometry for the study of proteins. We perform collaborative experiments with CCR researchers in areas such as: interactomes, quantitative global proteome analyses, and Read More...
Frederick, MD
Core Facility
Protein and Metabolite Characterization Core (PMCC), formerly known as the Protein Characterization Lab (PCL), offers various technologies to CCR investigators to characterize proteins and metabolites. The core develops and applies state-of-the-art analytical technologies, primarily mass Read More...
Bethesda, MD
Trans NIH Facility
The Division of Veterinary Resources Animal Surgery has supported large animal research and clinical care for more than 40 years. DVR surgeons provide outstanding and highly specialized large animal (rabbits, ungulates, etc.) research support in a Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New NIH Resource Resources Advance your research with the NIH Mouse Imaging Facility (MIF) The NIH Mouse Imaging Read More...
Frederick, MD
Core Facility
The function of the SAIP is to collaborate with NCI investigators in the development of mouse models, new molecular imaging probes for early detection and therapy, monitor tumors in vivo, and perform drug efficacy studies Read More...
Bethesda, MD
Trans NIH Facility
The NIH Center for Human Immunology, Inflammation, and Autoimmunity (CHI) is a trans-NIH resource whose mission is to provide a collaborative hub of advanced translational immunology for NIH clinical and pre-clinical studies. This uniquely structured Read More...
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CREx News & Updates August 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight NCATS Functional Genomics Laboratory (FGL) FGL is designed to help NIH Investigators use the latest Read More...
Bethesda, MD
Collaborative
Our operational objectives are to provide state-of-the-art OMICS technologies in support of the Genetics Branch (GB) investigators and collaborators. Research Services Wet Lab Single cell isolation from fresh, frozen, and FFPE tissue, DNA/RNA extractions Read More...
Web Page
Bioinformatics
09/30/2022 - The goal of this webinar series is to enhance understanding within the NCI and the research community of opportunities for targeting fusion oncoproteins through emerging chemoproteomic methods. This presentation will focus on computational tools Read More...
Web Page
Bioinformatics
07/17/2024 - Dear Colleagues, Please join us on Wednesday, July 17, 2024, when Dr. Olivier Gevaert from Stanford University will discuss leveraging data at different scales for personalized diagnosis, prognosis, and therapy in the fields of Read More...
Web Page
Bioinformatics
05/19/2022 - THIS EVENT HAS BEEN CANCELLED Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood and are subdivided into three major histomorphologic subtypes: alveolar (ARMS), embryonal (ERMS), or spindle/sclerosing (SSRMS). Patients with Read More...
Web Page
Bioinformatics
12/11/2023 - This presentation will provide a one-hour introduction to The AMARETTO software toolbox: multimodal and multiscale circuit-, network-, and graph-based fusion of multi-omics, clinical, imaging, and perturbation data across studies of patients, etiologies and model Read More...
Web Page
Bioinformatics
11/05/2018 - This introductory lecture will provide an overview of RNA-Seq technology, its various application and shortcomings, as well as detailing the steps involved in analyzing the resulting data. The specific topics covered include: What is Read More...
Web Page
Bioinformatics
12/16/2025 - Abstract: Spatial transcriptomics (ST) is evolving rapidly as a pivotal technology in studying the biology of tumors and their associated tumor microenvironments (TME). However, where/how it can impact research remain unclear. In this Read More...
Web Page
Bioinformatics
01/22/2024 - Dear Colleagues, Optical Genome Maps (OGM) provide scaffolding information for large DNA molecules. In this talk, we describe the use of this technology for detecting structural variants and chaining them Read More...
Web Page
Bioinformatics
12/12/2023 - Dr. Anant Madabhushi and his team have been developing computerized knowledge alignment, representation, and fusion tools for integrating and correlating heterogeneous biological data spanning different spatial and temporal scales, modalities, and functionalities. These tools Read More...
Web Page
Bioinformatics
There are a number of specific solutions that have been devised to address the issues created by attempting to map mRNA to DNA genomes. Each of these has its advantages and disadvantages. Align against the Read More...
Web Page
Bioinformatics
04/20/2022 - Qiagen IPA Land Explorer links out to the OmicSoft “Land” collections of disease-relevant datasets (>500,000 samples) directly from within IPA to: Explore sample-level data expression, variation, fusions, and more from 500,000+ datasets Explore full Read More...
Web Page
Bioinformatics
10/21/2021 - Announcing a FREE 30 day TRIAL to Qiagen IPA's Land Explorer (an add-on to the existing NCI Qiagen IPA license). If you are interested in access to the FREE TRIAL, please register for this Read More...
Web Page
Bioinformatics
06/09/2021 - The CCR Office of Science and Technology Resources (OSTR) is pleased to host a virtual technology seminar given by Advanced Cell Diagnostics (ACD) and NCI Cores at FNLCR. Presenters: Jyoti Phatak, MS | Advanced Cell Read More...
Web Page
Bioinformatics
07/27/2020 - The GDC RNA-Seq Analysis pipeline quantifies protein-coding gene expression. RNA-Seq data is aligned to the reference genome to detect splice junctions and then re-aligned to increase quality. Gene expression quantification and fusion detection are Read More...
Web Page
Bioinformatics
05/21/2019 - This introductory lecture will provide an overview of RNA-Seq technology, its various application and shortcomings, as well as detailing the steps involved in analyzing the resulting data. The specific topics covered include: What is Read More...
Web Page
Bioinformatics
06/16/2000 - We present the AMARETTO-Hub as a Knowledge Graph-based software platform that leverages Neo4j and Shiny to embed and interactively interrogate results generated by the *AMARETTO software toolbox that offers modular and complementary solutions Read More...
Web Page
Bioinformatics
07/11/2024 - Please join us for this special event featuring three speakers on the topic of Single-Cell Spatial Transcriptomics. George Zaki, Ph.D., Director, Applied Scientific Computing, BACS, The Frederick National Lab for Cancer Research, NCI/ Read More...
Web Page
Bioinformatics
01/19/2024 - Trey Ideker, Ph.D., is a professor of medicine, bioengineering, and computer science, and former chief of genetics at the University of California San Diego (UCSD). Additionally, he is director or co-director of the Read More...
Web Page
Bioinformatics
Bolyen E, Rideout JR, Dillon MR, Bokulich NA, Abnet CC, Al-Ghalith GA, Alexander H, Alm EJ, Arumugam M, Asnicar F, Bai Y, Bisanz JE, Bittinger K, Brejnrod A, Brislawn CJ, Brown CT, Callahan BJ, Caraballo-Rodrí Read More...
Web Page
Bioinformatics
References This course series primarily used information from QIIME2.org and the QIIME2 forum . Specifically, this course series focused on data and code from the QIIME2 Cancer Microbiome Intervention Tutorial . Special thanks goes to the Read More...
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Bioinformatics
Alignment RNASeq Mapping Challenges The majority of mRNA derived from eukaryotes is the result of splicing together discontinuous exons, and this creates specific challenges for the alignment of RNASEQ data. Mapping Challenges Reads not perfect Read More...
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Bioinformatics
08/24/2022 - Precision oncology has made significant advances, mainly by targeting actionable mutations and fusion events involving cancer driver genes. Aiming to expand treatment opportunities, recent studies have begun to explore the utility of tumor transcriptome Read More...
Web Page
Bioinformatics
06/06/2022 - Join the June NCI Imaging and Informatics Community Webinar for a discussion on the recent contributions from Dr. Mirabela Rusu’s Personalized Integrative Medicine Laboratory (PIMed) at Stanford University. Recent laboratory contributions include: registering Read More...
Web Page
Bioinformatics
02/08/2021 - Dear colleagues, Coming Monday, Feb 8th, we'll be having a guest lecture by Prof. Vineet Bafna from UCSD. Abstract: Increase in the number of copies of tumor promoting (onco-) genes is a hallmark Read More...
Web Page
Bioinformatics
05/21/2019 - This introductory lecture will provide an overview of RNA-Seq technology, its various application and shortcomings, as well as detailing the steps involved in analyzing the resulting data. The specific topics covered include: What is Read More...
Web Page
Bioinformatics
The nors data frame is not sorted. The .sort_values() attribute can be used to do this. Inside .sort_value(), the option by will be used to sort the NORS data by the variable(s) Read More...