NATIONAL CANCER INSTITUTE - CANCER.GOV

Core Resources

Chemistry and Structural Biology

Center for Structural Biology: Biophysics Resource
Frederick, MD

Core

Services Offered
Training Opportunities

The Biophysics Resource (BR) was established in January 2001. Our mission is to provide CCR investigators with access to both the latest instrumentation and expertise in characterizing the biophysical aspects of systems under structural investigation. The BR operates as an open, shared-use facility; in general, BR users learn to operate the instruments and conduct their own experiments. Biophysics Resource staff members train all first-time users and are also available to consult with investigators on experimental design/analysis or collaborate with them on more complex studies. Some of th… [learn more]

Facility Head: Sergey G. Tarasov
Email: tarasovs@mail.nih.gov
Phone: (301) 846-1223
NCI Synthetic Biologics Core
Frederick, MD

Core

Services Offered
Training Opportunities

The research conducted within the Synthetic Biologics Core (SBC) Facility has a dual role: 1) generate chemical biology tools and drug candidates for molecular targets identified by NCI research groups and 2) develop novel effective methods and tools for more effective molecular discovery. Chemical biology tools for studying protein functions have many advantages over applications of genetic approaches for studying protein functions. However, wide use of chemical probes is hampered by the difficulties in their generation and characterization. Because the majority of cancer drivers and proteins… [learn more]

Head: Nadya Tarasova
Email: nadya.tarasova@nih.gov
Phone: (301) 846-5225
NHLBI Biophysics Core
Bethesda, MD

Core

Services Offered
Training Opportunities

The Biophysics Core’s mission is to provide support in the study of macromolecular interactions, dynamics, and stability by offering consultations, training, professional collaborations, and instrument access. General Services: Multi-technique molecular interaction studies, Kinetic and thermodynamic characterization of interactions, Biophysical characterization of protein complexes and molecular assemblies, Biophysical characterization of integral membrane proteins, Characterization of exosomes, viruses and nanoparticles, Sample quality control and optimization, St… [learn more]

Facility Head: Grzegorz Piszczek, PhD
Email: piszczeg@nhlbi.nih.gov
Phone: (301) 435-8082