Resource Repository

The Biological Products Core provides the AIDS research community with high-quality purified preparations of various strains of Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV), economically prepared by leveraging the economy of scale. Materials provided include chemically inactivated virus prepared by treatment with Aldrithiol-2. This chemical inactivation method was developed by AIDS and Cancer Virus Program personnel and eliminates infectivity while preserving functional surface proteins, including envelope glycoproteins. This property makes them attractive prepara… [learn more]

Mouse models of human cancer have had a profound impact on our current understanding of the mechanisms of tumorigenesis and the pathways regulated by cancer-related genes. These models hold the promise of serving as critical tools in the discovery and testing of novel therapeutics to be used in the treatment and prevention of cancer. The Transgenic Mouse Model Laboratory (TMML) provides assistance to the scientific community with the generation of genetically engineered mice (GEM), offering a complete array of services aimed at the successful generation of tran… [learn more]