Data Repository

Thousands of molecular targets have been measured in the NCI panel of 60 human tumor cell lines. Measurements include protein levels, RNA measurements, mutation status, and enzyme activity levels. You can choose to search for a target of interest, or you may browse through a list of targets. Follow the links for a target to retrieve the 60 cell line data (either text or graphical), to run COMPARE (find targets or compounds whose patterns correlate with a target of interest), and to link to various databases with information (function, sequences, disease associations) about the target. E… [learn more]

The NCI Cloud Resources are components of the NCI Cancer Research Data Commons (CRDC) that bring data and computational power together to enable cancer research and discovery. These cloud-based platforms eliminate the need for researchers to download and store large data sets by allowing them to bring analysis tools to the data in the cloud, instead of the traditional process of bringing the data to the tools on local hardware. Cancer Research Data Commons (CRDC) Access harmonized, multi-omics cancer data – Data are available in nodes, harmonized and stored in a format that is ready for… [learn more]

The NCI Genomic Data Commons (GDC) was established by the NCI Center for Cancer Genomics (CCG) to support the receipt, harmonization, distribution, and analysis of genomic and clinical data from cancer research programs. The GDC provides the cancer research community with a repository and computational platform for cancer researchers who need to understand cancer, its clinical progression, and response to therapy. The GDC accomplishes this by harmonizing raw sequence data against a common reference genome (GrCH38), applying state-of-the-art methods for generating high-level data such as mutati… [learn more]

Proteomic Data Common (PDC) represents the NCI’s largest public repository of proteogenomic comprehensive tumor datasets, essentially a Proteogenomic Cancer Atlas. It was developed to advance our understanding of how proteins help shape the risk, diagnosis, development, progression, and treatment of cancer. The objectives are (1) to make cancer-related proteomic data sets easily accessible to the public, and (2) facilitate multi-omic integration in support of precision medicine through interoperability with other resources. The PDC uses a cloud-based approach by storing all data sets with Am… [learn more]

With specimens that span neurological, neuropsychiatric, and neurodevelopmental diseases and disorders, the NBB serves as a central point of access to the world-class collections of our six biorepositories. In addition, the NBB provides researchers with a wealth of resources to facilitate their research, including medical records and clinical data sets (when available) as well as access to quality metrics and best practices used by each site. Established Technologies The NIH NeuroBioBank contains an inventory of specimens that are available through its brain and tissue repository network, … [learn more]