Clinical Research Support

CLIA-Certified Technologies Offered: Fragment Analysis for Micro-satellite Instability Detection, Pharmacoscan Array for Pharmacogenomics, Mutation Detection for PCR and Sanger Sequencing, DNA extraction from whole blood, saliva, FFPE tissues, buccal swabs, nails, hair, PBMCs, buffy coats, plasma, tissue slides, cell lines, frozen tissues, and platelet-depleted whole blood, Droplet Digital PCR (ddPCR), Mass Spectrometry, Additional Capabilities Include: Quantitative PCR (qPCR), Next-Generation Sequencing (NGS), Automated Staining (RNAscope), Gene… [learn more]

The Clinical Support Laboratory offers processing, tracking, and testing of a broad range of clinical samples. Support can begin at the early stages of clinical trial development to aid in developing a comprehensive strategy for sample collection, processing, and testing with a special emphasis on immunologic testing. The lab collaborates with partners to develop customized assays or transfer existing assay technology with assay validation, data analysis and interpretation of results. Processing specializes in PBMC isolation and controlled rate freezing, ELISA based biomarker testing, and … [learn more]

Clinical Support Laboratory – Cellular Immunology offers a spectrum of bioassays to assess cellular responses to antigens and mitogens including ELISPOT, cytotoxicity assays, and proliferation assays. Established Technologies Elispot Assays, Dual or Triple Color Fluorospot Assays, Murine Immunoassays, Cytotoxic T cell assays (Chromium Release Assays), Antigen and mitogen-induced cell proliferation, Mixed Lymphocyte Reactions, Antibody-Dependent Cell-Mediated Cytotoxicity, Cell Metabolic Analysis via Seahorse, In vitro Stimulation/Cytoki… [learn more]

The Blood Processing Core monitors viral load in patients with HIV and performs sequential studies using samples obtained from patients with cancer, AIDS, chronic granulomatous disease, or other diseases associated with immunologic dysfunction. The core collects clinical specimens from inpatient units and clinics within the National Institutes of Health Clinical Center. We then oversee the processing and cryopreservation of human serum, plasma, peripheral blood mononuclear cells, and other specimens. Our technicians are also trained and qualified to execute preclinical animal protocols and ro… [learn more]

The Magnetoencephalography (MEG) Core Facility specializes in MEG, a non-invasive procedure similar to electroencephalography (EEG), and aims to support research to better understand of the functioning of the brain. Established Technologies Magnetoencephalography (MEG) is a non-invasive procedure similar to electroencephalography (EEG) in terms of basic principles and analysis, however, MEG consists of sitting in a chair or lying on a bed while your head is inside a helmet shaped device which contains magnetic field sensors. These superconducting quantum interference device (SQUID) sensors … [learn more]