Core Resources
Clinical Research Support
CLIA Molecular Diagnostics Laboratory
Frederick, Maryland
Core
CLIA-Certified Technologies Offered: Fragment Analysis for Micro-satellite Instability Detection, Pharmacoscan Array for Pharmacogenomics, Mutation Detection for PCR and Sanger Sequencing, DNA extraction from whole blood, saliva, FFPE tissues, buccal swabs, nails, hair, PBMCs, buffy coats, plasma, tissue slides, cell lines, frozen tissues, and platelet-depleted whole blood, Droplet Digital PCR (ddPCR), Mass Spectrometry, Next-Generation Sequencing (NGS), Additional Capabilities Include: Quantitative PCR (qPCR), Automated Staining (RNAscope), GeneChip… [learn more]
Clinical Support Laboratory (Cellular Immunology / Cell Culture, Lymphokine Testing Section, Clinical Trials Processing)
Frederick, MD
Core
Clinical Support Laboratory – Cellular Immunology / Cell Culture offers a spectrum of bioassays to assess cellular responses to antigens and mitogens (flow cytometry, ELISpot/Fluorospot, cytotoxicity assays, proliferation assays). This section also offers Olink assay (Target panels and Reveal). This section also generates fibroblasts from skin biopsies, EBV-transformed cell lines, and expands existing cell lines. Clinical Support Laboratory– Lymphokine Testing Section runs and analyzes research samples (e.g. human, mouse, NHP, rat) for biomarkers in serum, plasma, cell culture supe… [learn more]
NCI Clinical Pharmacology Program (CPP): Blood Processing Core
Bethesda, MD
Core
The Blood Processing Core monitors viral load in patients with HIV and performs sequential studies using samples obtained from patients with cancer, AIDS, chronic granulomatous disease, or other diseases associated with immunologic dysfunction. The core collects clinical specimens from inpatient units and clinics within the National Institutes of Health Clinical Center. We then oversee the processing and cryopreservation of human serum, plasma, peripheral blood mononuclear cells, and other specimens. Our technicians are also trained and qualified to execute preclinical animal protocols and ro… [learn more]
NIMH Magnetoencephalography (MEG) Core Facility
Bethesda, Maryland
Core
The Magnetoencephalography (MEG) Core Facility specializes in MEG, a non-invasive procedure similar to electroencephalography (EEG), and aims to support research to better understand of the functioning of the brain. Established Technologies Magnetoencephalography (MEG) is a non-invasive procedure similar to electroencephalography (EEG) in terms of basic principles and analysis, however, MEG consists of sitting in a chair or lying on a bed while your head is inside a helmet shaped device which contains magnetic field sensors. These superconducting quantum interference device (SQUID) sensors … [learn more]