The SAXS Core facility is a CCR resource dedicated to the CCR researchers. But we also make this resource accessible to non-CCR users free of charge. For more details, please visit our website.

To request services from this CCR core facility, please contact Lixin Fan and Yun-Xing Wang.

FOR ALL NIH PROJECTS PLEASE CONTACT DINA DIRECTLY VIA EMAIL dina.sigano@nih.gov ****

The facility’s capabilities include:

• Providing expertise, consultation and experience in areas of chemical synthesis and purification.
• Providing custom synthesis and support for the development of small molecule tools or the synthesis of known ligands or probes which are not commercially available.
• Synthesis of materials for pre-clinical investigations.
• Support for small-molecule drug discovery through optimization of leads identified in high throughput screens.
• Collaborative short-term sabbatical-type opportunities for post-doctoral fellows who wish to gain synthetic chemistry experience.

The Chemical Synthesis Group provides a means to access chemical technology for those groups within the NCI Intramural community which would not otherwise be capable of exploring these aspects of their research.

User Guidelines

To request services from this CCR facility, please contact Dina Sigano directly via email at dina.sigano@nih.gov ****

Established Technologies

• High-resolution structural analysis of sugars, glycopeptides and small molecule drug candidates by NMR spectroscopy. Collaborative projects with NCI Researchers