Web Page
Bioinformatics
09/29/2022 - The size and complexity of data necessary to derive meaningful scientific and clinical insights are advancing at an unprecedented rate. At the core of this complexity is an ever-expanding array of technologies, instrumentation, and Read More...
Web Page
Bioinformatics
08/30/2024 - This course is designed to provide participants with an introduction to R programming, specifically focusing on data wrangling techniques. Throughout the course, participants will gain a comprehensive understanding of how to effectively use RStudio, Read More...
Web Page
Bioinformatics
05/29/2024 - This talk will cover a scRNA-seq workflow available to NCI researchers on NIDAP. NIDAP, the NIH Integrated Data Analysis Platform, is a cloud-based and collaborative data aggregation and analysis platform that hosts user-friendly bioinformatics Read More...
Web Page
Bioinformatics
Josh Meyer, bioinformatics analyst (CCBR), will cover a scRNA-seq workflow available to NCI researchers on NIDAP . NIDAP, the NIH Integrated Data Analysis Platform, is a cloud-based and collaborative data aggregation and analysis platform that hosts Read More...
Web Page
Bioinformatics
The CCBR Single-cell RNA-seq Workflow on NIDAP Josh Meyer, bioinformatics analyst (CCBR), will cover a scRNA-seq workflow available to NCI researchers on NIDAP . NIDAP, the NIH Integrated Data Analysis Platform, is a cloud-based and collaborative Read More...
Web Page
Bioinformatics
06/29/2022 - The CCR Genomics, Sequencing and Single Cell Analysis Core Facilities are pleased to host a virtual technology seminar with Illumina. Presentation overview : For decades cancer methylation studies have provided insights into tumorigenic pathways and Read More...
Web Page
Bioinformatics
Reproducibility in science means being able to generate the same experimental / analytical results with a high degree of reliability. This is necessary for research validation, scientific and public trust, innovation, and collaboration. Reproducibility is not Read More...
Web Page
Bioinformatics
Reproducibility in science means being able to generate the same experimental / analytical results with a high degree of reliability. This is necessary for research validation, scientific and public trust, innovation, and collaboration. Reproducibility is not Read More...
Web Page
Bioinformatics
NIDAP is the NIH Integrated Data Analysis Platform (NIDAP). NIDAP is an innovative, cloud-based, collaborative data aggregation and analysis platform that hosts user-friendly bioinformatics workflows and component analysis and visualization tools developed by the NCI Read More...
Web Page
Bioinformatics
NIDAP is an innovative, cloud-based, collaborative data aggregation and analysis platform that hosts user-friendly bioinformatics workflows and component analysis and visualization tools developed by the NCI developer community based on open source tools and makes Read More...
Web Page
Bioinformatics
05/22/2024 - Are you attending the 2024 AMIA Clinical Informatics Conference ? Join NCI Fellow, Austin Fitts, as he presents on the National Childhood Cancer Registry (NCCR) during the May 22 afternoon sessions. Read More...
Web Page
Bioinformatics
Reproducibility in science means being able to generate the same experimental / analytical results with a high degree of reliability. This is necessary for research validation, scientific and public trust, innovation, and collaboration. Reproducibility is not Read More...
Web Page
Bioinformatics
12/14/2023 - NIDAP , the NIH Integrated Data Analysis Platform, is a cloud-based, collaborative data aggregation and analysis platform that hosts user-friendly bioinformatics workflows and other component analysis and visualization tools. The NCI CCR Collaborative Bioinformatics Resource ( Read More...
Web Page
Bioinformatics
12/06/2023 - NIDAP, the NIH Integrated Data Analysis Platform, is a cloud-based and collaborative data aggregation and analysis platform. The NIDAP platform hosts user-friendly bioinformatics workflows (Bulk RNA-Seq, scRNA-Seq, Digital Spatial Profiling) and other component analysis Read More...
Web Page
Bioinformatics
Bash Most of bioinformatics can be done by understanding specific software applications and running those applications in a pipeline, usually using some form of bash scripting. Bash as a scripting language is fairly important for Read More...
Web Page
Bioinformatics
Bash Most of bioinformatics can be done by understanding specific software applications and running those applications in a pipeline, usually using some form of bash scripting. Bash as a scripting language is fairly important for Read More...
Web Page
Bioinformatics
05/23/2023 - NIH Text Mining and Natural Language Processing SIG is pleased to welcome you to a special event dedicated to Large Language Models. Abstract : The release of ChatGPT and the subsequent launch of GPT-4 by Read More...
Web Page
Bioinformatics
11/16/2021 - Presenter: Rahul Satija, PhD, is a Core Faculty Member at the New York Genome Center (NYGC), with a joint appointment as Associate Professor at the Center for Genomics and Systems Biology at New York Read More...
Web Page
Bioinformatics
11/16/2021 - The NCI HALO cloud deployment provides NCI researchers with powerful image management and analysis tools for digital pathology and numerous other 2D imaging applications. Key capabilities include expert user assessment, image archiving, and advanced Read More...
Web Page
Bioinformatics
09/19/2021 - At the Conference on Machine Intelligence in Medical Imaging, NCI Imaging Data Commons (IDC) lead, Dr. Keyvan Farahani, will present NCl's cancer data science resources that support the imaging informatics community. As the Read More...
Web Page
Bioinformatics
03/10/2021 - Register now to watch the presentation The term “data commons” is used across NIH to describe data-hosting repositories. But data commons can differ widely in what they offer, from simple storage and infrastructure to Read More...
Web Page
Bioinformatics
01/04/2021 - Abstract: Phenotypic heterogeneity in cancer is often caused by different patterns of genetic alterations. Understanding such phenotype-genotype relationships is fundamental for the advance of personalized medicine. In this talk, I will present a computational Read More...
Web Page
Bioinformatics
NIDAP (NIH Integrated Data Analysis Platform) is an innovative, cloud-based, collaborative data aggregation and analysis platform that hosts user-friendly bioinformatics workflows and component analysis and visualization tools developed by the NCI developer community based on Read More...
Web Page
Bioinformatics
In the chart view, we are presented with the disease(s) found in a particular database that our input genes map to. Notice that we can sort this list by gene count, percentage, p-value, or Read More...
Web Page
Bioinformatics
PCA is mostly used in genomics for dimensionality reduction and uncovering patterns in highly dimensional data, including identifying technical and biological variation. Examples of applications in genomics: RNA-Seq Batch correction. Identifying Co-expressed Genes. scRNA-Seq Dimensionality Read More...
Frederick, MD
Core Facility
The Biophysics Resource (BR) was established in January 2001. Our mission is to provide CCR investigators with access to both the latest instrumentation and expertise in characterizing the biophysical aspects of systems under structural investigation. The Read More...
Web Page
Discover expert help with analysis, processing applications, and licensed software packages.
Web Page
Home About the Biophysics Core Biophysics Core Services [tabby title="Instrumentation"] NHLBI Biophysics Core The Biophysics Core Facility: Overview Core Facilities provide scientific resources, cutting-edge technologies and novel approaches to support DIR scientists. Availability of Read More...
Web Page
Bioinformatics
Register now for an upcoming seminar on January 22, 2025 , “Revealing Tumor-Promoting Signals in Breast Cancer Subtypes: A NIDAP Analysis of Single-Cell Data” . This one-hour talk will feature guest speaker and NIDAP developer, Josh Meyer, who will Read More...
Web Page
Bioinformatics
Clinicians and bench scientists (a.k.a., wet lab researchers) are at the forefront of scientific achievement. However, most, if not all contemporary projects involve robust scientific analysis, where the tools of exploration aren’t Read More...
Web Page
Bioinformatics
Following Cell Ranger and/or other pre-processing tools, you will have a gene-by-cell counts table for each sample. The three most popular frameworks for analyzing these count matrices include: R ( Seurat ). Seurat, brought to you Read More...
Web Page
Bioinformatics
12/08/2023 - This presentation will discuss strategies and policies for effective sharing and reuse of large multidimensional datasets. Dr. Espinosa will discuss his experiences as a data generator, data analyst, collaborator, teacher, and mentor through the Read More...
Web Page
Bioinformatics
09/08/2023 - Hybrid Seminar Friday, September 8, 2023 • 9:00-10:00 a.m. Building 549 Auditorium (In-person attendance encouraged) Speaker: Brian Kelsall, M.D. Senior Investigator, Mucosal Immunobiology Section Laboratory of Molecular Immunology National Institutes of Allergy Read More...
Web Page
Bioinformatics
NIDAP , the N IH I ntegrated D ata A nalysis P latform, is an innovative, cloud-based, and collaborative data aggregation and analysis platform. The platform Read More...
Web Page
Bioinformatics
The test data consists of two commercially available RNA samples: Universal Human Reference (UHR) and Human Brain Reference (HBR) . The UHR is total RNA isolated from a diverse set of 10 cancer cell lines. The HBR Read More...
Web Page
Bioinformatics
The test data consists of two commercially available RNA samples: Universal Human Reference (UHR) and Human Brain Reference (HBR) . The UHR is total RNA isolated from a diverse set of 10 cancer cell lines. The HBR Read More...
Web Page
Bioinformatics
This page uses content directly from the Biostar Handbook by Istvan Albert. Obtain RNA-seq test data. The test data consists of two commercially available RNA samples: Universal Human Reference (UHR) and Human Brain Reference (HBR) . Read More...
Web Page
Bioinformatics
This page uses content directly from the Biostar Handbook by Istvan Albert. Obtain RNA-seq test data. The test data consists of two commercially available RNA samples: Universal Human Reference (UHR) and Human Brain Reference (HBR) . Read More...
Web Page
Bioinformatics
The test data consists of two commercially available RNA samples: Universal Human Reference (UHR) and Human Brain Reference (HBR) . The UHR is total RNA isolated from a diverse set of 10 cancer cell lines. The HBR Read More...
Web Page
Bioinformatics
06/09/2023 - Dr. Nara Sobreira will present "PhenoDB, a phenotypic and genotypic data sharing tool" at the monthly Data Sharing and Reuse Seminar on June 9, 2023, at 12 p.m. EST. About the Seminar This seminar Read More...
Web Page
Bioinformatics
08/10/2022 - For our next CDSL webinar we will have two fellows’ talks from Dr. Zisha Zhong and Arati Rajeevan . Zisha’s talk details: Title: Multi-task Feature Learning to train Interpretable Encoders on Histopathology Images Digital Read More...
Web Page
Bioinformatics
03/30/2022 - Predicting how changes in the genome manifest as phenotypic differences is an extremely challenging problem that requires a deep understanding of multiscale biological mechanisms. And while we know a great deal about how information Read More...
Web Page
Bioinformatics
06/05/2020 - Dr. Anuradha Budhu began her scientific career as a student researcher in the Undergraduate Biology Research Program (UBRP) at the University of Arizona, studying gene expression patterns in the larval brain of Drosophila Melanogaster. Read More...
Web Page
Bioinformatics
1) Create a ranked list of genes. More on ranking metrics below. 2) Select gene sets to test. There are many available databases with pre-defined gene sets. You should choose gene sets relevant to your experimental conditions / Read More...
Web Page
Bioinformatics
Enrichment Score and normalized enrichment score. Enrichment Score - represents the degree to which a set is over-represented at the top or bottom of the ranked list. normalized enrichment score (NES) - allows comparability across Read More...
Web Page
Bioinformatics
The Functional Annotation Clustering tool groups similar annotations together to reduce the redundancy seen in the Functional Annotation Chart results. This eases the interpretation of the findings. The Functional Annotation Clustering integrates the same techniques Read More...
Web Page
Back Services: Biophysics Facility offers DLS as an open-access instrument. First-time users must complete a short training session before gaining access to the instrument reservation calendar. Training includes DLS analysis of small- and large-molecular size Read More...
Web Page
Back Services: We offer a limited sample processing service using standard SEC-MALS and FFF protocols. This service is intended for the occasional users of this system. Researchers who expect to use this instrument Read More...
Web Page
Back Services: We offer a limited sample processing service using standard SEC-MALS and FFF protocols. This service is intended for the occasional users of this system. Researchers who expect to use this instrument Read More...
Web Page
Cores & Facilities From centralized laboratories to collaborative resources and technologies available to CCR Investigators. NCI Cores Centralized laboratories providing broad access to cutting-edge technologies and specialized expertise. Browse NCI Cores Collaborative Resources are technologies and Read More...
Bethesda, MD
Collaborative
The CCR Collaborative Bioinformatics Resource (CCBR) is a centrally funded resource group which provides a mechanism for CCR researchers to obtain many different types of bioinformatics assistance to further their research goals. The group has Read More...
Web Page
Back Services: This instrument is not user accessible. We provide both data collection and data analysis services. Location: Building 50, room 3331 Description: An analytical ultracentrifuge is equipped with absorption and interference optical systems that monitor Read More...
Frederick, MD
Collaborative
In order to meet increasing demands from both NIH intramural and extramural communities for access to a small angle X-ray scattering (SAXS) resource, the Center for Cancer Research (CCR) under the leadership of Drs. Jeffrey Read More...
Rockville, MD
Trans NIH Facility
The Chemistry and Synthesis Center (CSC) of the National Heart, Lung, and Blood Institute (NHLBI) provides IRP scientists with targeted imaging probes and chemical tools that help accelerate cell-based assays, in vivo imaging studies, and Read More...
Web Page
Bioinformatics
This lesson provides an introduction to R in the context of single cell RNA-Seq analysis with Seurat. Learning Objectives Learn about options for analyzing your scRNA-Seq data. Learn about resources for learning R programming. Learn Read More...
Web Page
Bioinformatics
Objectives To explore Bioconductor, a repository for R packages related to biological data analysis. To learn about options for report generation with R: RMarkdown and Quarto. Introducing Bioconductor Bioconductor is both an open source project Read More...
Web Page
Bioinformatics
This page uses content directly from the Biostar Handbook by Istvan Albert. Obtain RNA-seq test data. The test data consists of two commercially available RNA samples: Universal Human Reference (UHR) and Human Brain Reference (HBR) . Read More...
Web Page
Bioinformatics
Learning Objectives Learn about popular programming languagues in bioinformatics Compare advantages and disadvantages of Python and R Discuss what you will need to learn to use these languages Discuss learning resources Choosing a programming language Read More...
Web Page
Bioinformatics
Learning Objectives Learn about popular programming languagues in bioinformatics Compare advantages and disadvantages of Python and R Discuss what you will need to learn to use these languages Discuss learning resources Choosing a programming language Read More...
Web Page
Bioinformatics
Whether you are measuring mRNA expression, protein expression, DNA methylation, expressed miRNAs, protein binding to DNA or RNA, etc., you will likely end up with a list of genes or gene products from which you Read More...
Web Page
Bioinformatics
There are a number of core facilities available to NCI researchers. See more information from the Office of Science and Technology Resources. We most commonly see data from the following cores: CCR Sequencing Facility (CCR-SF) Read More...
Web Page
Bioinformatics
The resulting object eh is a gseaResult object. This object contains the results (eh@result) and other information that went into the analysis, for example, @organism type, @setType, the @geneSets used, the genes in our @ Read More...