Frederick, MD
Repositories
Trans NIH Facility
DTP’s Natural Products Repository is the world’s largest storehouse of natural products. It houses close to >200,000 extracts from samples of more than 70,000 plants and >20,000 marine organisms collected from more than 29 countries, plus extracts Read More...
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Bioinformatics
04/02/2021 - Speaker: Tonia Korves, Ph.D. Lead Data Scientist Data and Human-Centered Solutions Innovation Center MITRE Corporation Abstract As COVID-19 research rapidly escalated last year, we quickly built a platform to help biomedical experts track Read More...
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Bioinformatics
02/23/2024 - Register for this presentation on recent efforts in developing methodologies and software tailored for important clinical natural language processing (NLP) tasks such as information extraction and question answering. Advancements in large language Read More...
Frederick, Maryland
Core Facility
Repositories
The Biological Products Core provides the AIDS research community with high-quality purified preparations of various strains of Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV), economically prepared by leveraging the economy of scale. Materials Read More...
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Bioinformatics
04/07/2025 - AI Club is a weekly meeting that explores various topics relating to AI and deep learning in biomedical sciences, typically in a seminar, workshop, or journal club format. AI Club is intended to be Read More...
Frederick, MD
Collaborative
The Molecular Targets Program (MTP) is an organizational entity within the Center for Cancer Research (CCR) at NCI. The MTP provides the focus and infrastructure to enable CCR tenured and tenure-track Principal Investigators to initiate Read More...
Rockville, MD
Repositories
Trans NIH Facility
DTP maintains a repository of synthetic compounds and pure natural products that are available to investigators for non-clinical research purposes. The Repository collection is a uniquely diverse set of more than 200,000 compounds that have been Read More...
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Bioinformatics
GO terms provide information about a gene product GO terms as a vocabulary are species agnostic, but there are species constraints ontology and annotations are updated regularly computer readable - suitable for bioinformatics GO integrates Read More...
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Bioinformatics
GO terms provide information about a gene product GO terms as a vocabulary are species agnostic, but there are species constraints ontology and annotations are updated regularly computer readable - suitable for bioinformatics GO integrates Read More...
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Bioinformatics
IPA and CLC Genomics Workbench are both Qiagen products, which allows us to more easily extract biological insight from analysis. For this reason, it is beneficial to use these two packages together.
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Confocal
2024 Date: Tuesday, October 15, 2024 Time and Location: 11 am EST, ZOOM (INVITATION BY LMIG LIST SERVER) Speaker: Dr. Diego Presman (U Buenos Aires) Title: “Insights on Glucocorticoid Receptor Activity Through Live Cell Imaging” Summary: Eucaryotic transcription factors ( Read More...
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Bioinformatics
01/14/2025 - Join us for a webinar on EMERSE, a text processing system designed specifically for non-technical users, featuring David Hanauer, M.D., M.S. from the University of Michigan Medical School. EMERSE (Electronic Medical Record Read More...
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Bioinformatics
06/14/2023 - Generative modeling is an artificial intelligence (AI) technique that creates unique content (such as text, graphics, audio, and video) by first analyzing training examples. Generative AI includes ChatGPT, which generates text in Read More...
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Bioinformatics
The object ( scaled_counts ) that we imported is a data frame. Data frames hold tabular data, like much of the data stored in spreadsheets. They are collections of vectors of the same length, but can Read More...
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Bioinformatics
10/15/2021 - This course will introduce you to Google Cloud's big data and machine learning functions. You'll begin with a quick overview of Google Cloud and then dive deeper into its data processing capabilities. Read More...
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Bioinformatics
11/18/2020 - Register RStudio will be planning quarterly webinars to support the HHS Data Science and Statistical Programming communities. The first installment will be focused on Creating Reproducible Data Science. Please join Alex Gold as he Read More...
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Bioinformatics
11/13/2020 - Register RStudio will be planning quarterly webinars to support the HHS Data Science and Statistical Programming communities. The first installment will be focused on Creating Reproducible Data Science. Please join Alex Gold as he Read More...
Frederick, MD
Collaborative
The Biopharmaceutical Development Program (BDP) provides resources for the development of investigational biological agents. The BDP supports feasibility through development and Phase I/II cGMP manufacturing plus regulatory documentation.The BDP was established in 1993. We Read More...
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Bioinformatics
09/09/2025 - Join&nb p;the National Heart, Lung, and Blood In titute (NHLBI)&nb p;for a hybrid work hop to explore how medicine will be tran formed by the current artificial intelligence ( Read More...
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Bioinformatics
04/01/2025 - Whether you are measuring mRNA expression, protein expression, DNA methylation, expressed miRNAs, protein binding to DNA or RNA, etc., you will likely end up with a list of genes or gene products from which Read More...
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Bioinformatics
11/12/2024 - Join us at the upcoming hybrid NIH BRAIN NeuroAI Workshop on November 12 and 13, with virtual access to in-person panels and discussions at the NIH Campus in Bethesda, MD. Artificial intelligence (AI) is reshaping technology Read More...
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Bioinformatics
09/30/2024 - In this webinar, you'll gain insights into the Electronic Medical Record Search Engine (EMERSE). EMERSE is a simple, powerful tool to help researchers like you identify key data within free text clinical notes Read More...
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Bioinformatics
06/27/2024 - In this in-person session, participants will have an opportunity to discuss their own research and use of Qiagen products with Qiagen scientists. Note on Technology Participants are expected to bring Read More...
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Bioinformatics
The total number of detected transcripts expressed in a cell is dependent on the amount of mRNA in a cell. Cells naturally vary in the total amount of mRNA expressed. However, the chemistry of the Read More...
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Bioinformatics
In genomics, we work with a lot of tabular data - data organized in rows and columns. The data structure that stores this type of data is a data frame . Data frames are collections of Read More...
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Bioinformatics
Many of the tools used to understand functional enrichment will use sets of GO terms, examining GO enrichment. What do we mean by GO? The Gene Ontology (GO) provides a framework and set of concepts Read More...
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Bioinformatics
05/23/2023 - NIH Text Mining and Natural Language Processing SIG is pleased to welcome you to a special event dedicated to Large Language Models. Abstract : The release of ChatGPT and the subsequent launch of GPT-4 by Read More...
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Bioinformatics
02/09/2023 - NCI announces availability of the institute-wide site license for MATLAB that provides access to MATLAB, Simulink, and additional products on government-furnished equipment to all NCI staff, including fellows, contractors, and trainees. These powerful tools Read More...
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Bioinformatics
10/05/2022 - In this seminar, Project Rōnin’s Vice President of Data Science , Dr. Christine Swisher, will discuss the challenges of ensuring safe and ethical artificial intelligence (AI) in healthcare. Specifically, Dr. Swisher will examine: Read More...
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Bioinformatics
09/21/2022 - Join University of Colorado’s Dr. Arjun Krishnan as he discusses how machine learning and natural language processing can contribute to making public -omics data more accessible. Dr. Krishnan will also present the recent Read More...
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Bioinformatics
10/11/2021 - This course uses lectures, demos, and hands-on labs to give you an overview of Google Cloud products and services so that you can learn the value of Google Cloud and how to incorporate cloud-based Read More...
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Bioinformatics
04/08/2020 - Accelerating discovery requires fast access to genomic data as well as on-demand computational resources. NCBI, with support from NIH's STRIDES initiative, has moved all of the Sequence Read Archive (SRA) to the Google ( Read More...
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Bioinformatics
03/06/2020 - The NIH Office of Data Science Strategy (ODSS) is presenting NIH Figshare for NIH Intramural Researchers: A Generalist Repository for Data Sharing on March 6 at 12:00 p.m. This one-hour webinar will explore how NIH Read More...
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Bioinformatics
01/10/2020 - In this introductory course, you will learn about AWS products, services, and common solutions. You will learn the fundamentals of identifying AWS services so that you can make informed decisions about IT solutions based Read More...
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Bioinformatics
05/07/2013 - This 2 hour seminar will be an interactive discussion and demonstration of the types of applications and work-flows that can be performed on deep sequencing data generated by the latest instruments from Illumina, Life Technologies ( Read More...
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Bioinformatics
10/30/2012 - Due to the weather related shutdown of the FEDERAL GOVERNMENT (NIH) this seminar has been POSTPONED ... we will attempt to reschedule at a later date. (10-30-2012) Topics to be covered I. Genomic and Read More...
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Bioinformatics
In genomics, we work with a lot of tabular data - data organized in rows and columns. The data structure that stores this type of data is a data frame. Data frames are collections of Read More...
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Bioinformatics
RStudio is an integrated development environment for R, and now python. RStudio includes a console, editor, and tools for plotting, history, debugging, and work space management. It provides a graphic user interface for working with Read More...
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Bioinformatics
Many of the tools used to understand functional enrichment will use sets of GO terms, examining GO enrichment. What do we mean by GO? The Gene Ontology (GO) provides a framework and set of concepts Read More...
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Bioinformatics
ssh (connect to remote computer such as a high performance computing cluster) pwd (print working directory) cd (change directory) ls (list directory content) mkdir (make a directory) touch (creates an empty file) nano (basic editor Read More...
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Bioinformatics
GO enrichment refers specifically to gene ontology. The Gene Ontology (GO) provides a framework and set of concepts for describing the functions of gene products from all organisms. --- https://www.ebi.ac.uk/ols/ Read More...
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Intelligent and automated flow cytometry panel designer for traditional and spectral cytometers EasyPanel is an easy-to-use, fully automated panel designer for flow cytometry that is integrated with an automated Antibody Stock management system. The tool Read More...
Frederick, MD
Core Facility
Protein Characterization Laboratory (PCL) offers various technologies to CCR investigators to characterize proteins and metabolites. The laboratory develops and applies state-of-the-art analytical technologies, primarily mass spectrometry, liquid chromatography, and Surface Plasmon Resonance (SPR), to advance Read More...
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The NIH Intramural Research Program Collaborative Research Exchange (CREx) The Collaborative Research Exchange (CREx) is an online CCR marketplace where investigators can search, browse, and request information for research services, technologies, or custom products (antibody Read More...
Bethesda, MD
Collaborative
The Behavioral Health Core (BHC) is comprised of the two separate but interrelated components: Psychosocial Support and Research Program, and, Health Psychology and Neurobehavioral Research Program., These teams provide specialized expertise, such as patient-reported and Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Cores on CREx NIBIB BEPS Micro Analytical Immunochemistry Unit The Micro Analytical Immunochemistry Unit employs a variety Read More...
Bethesda, MD
Trans NIH Facility
The NIH Clinical Center Pharmacy Department provides pharmaceutical care to inpatients and outpatients on NIH intramural research protocols at the NIH Clinical Center. The Clinical Center facility encompasses 200 inpatient beds, 93 day-hospital stations, and 15 clinics. Clinical Read More...
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Bioinformatics
10/24/2024 - NIH Text Mining and Natural Language Processing SIG is pleased to welcome you to this special event featuring two extraordinary speakers focused on the applications of Deep Learning in Computational Biology. & Read More...
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Bioinformatics
Try googling your problem or using some other search engine. rseek is an R specific search engine that searches several R related sites. If using google directly, make sure you use R to tag your Read More...
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Bioinformatics
The data type of an R object affects how that object can be used or will behave. Examples of base R data types include numeric, integer, complex, character, and logical. R objects can also have Read More...
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Bioinformatics
Work through DNAnexus? Find a nice cancer data set for 16S and shotgun Divide into two workshops or courses? Course structure or workshop structure? Amplicon processing and analysis (5 week course) (4 weeks) 1. Talk by Greg Caparaso? 1. Read More...
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Bioinformatics
Microbiome Course Course Outline Work through DNAnexus? Find a nice cancer data set for 16S and shotgun Divide into two workshops or courses? Course structure or workshop structure? Amplicon processing and analysis (5 week course) (4 weeks) 1. Read More...
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Bioinformatics
12/07/2023 - This hands-on workshop will introduce the Ingenuity Pathway Analysis (IPA) and CLC Genomics Workbench tools, which are available to access from the NIH Library. IPA can be used identify biological relationships, mechanisms, pathways, functions, Read More...
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Bioinformatics
There are many databases devoted to relating genes and gene products to pathways, processes, and other phenomenon. Again, the following is not meant to be a comprehensive list. Kyoto Encyclopedia of Genes and Genomes (KEGG) Read More...
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Bioinformatics
Gene ontology and pathway analysis Objectives Determine potential next steps following differential expression analysis. Tour geneontology.org and understand the three main ontologies. Learn about different methods and tools related to functional enrichment and pathway Read More...
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Bioinformatics
Now that we have downloaded the HBR and UHR dataset and know where analysis tools are, let's start learning about RNA sequencing, by first learning about our reference genome and annotation files. Let's Read More...
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Bioinformatics
Now that we have downloaded the HBR and UHR dataset and know where analysis tools are, let's start learning about RNA sequencing, by first learning about our reference genome and annotation files. Let's Read More...
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Bioinformatics
Try googling your problem or using some other search engine. rseek is an R specific search engine that searches several R related sites. If using google directly, make sure you use R to tag your Read More...
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Bioinformatics
R objects have certain attributes, and these attributes will be important for how they can interact with certain methods / functions. Understanding the mode (storage type) or the class of an object will be important for Read More...
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Bioinformatics
09/28/2022 - We invite you to join us for the Neuro-Oncology Visiting Scholar Lecture scheduled for next week by Eytan Ruppin, M.D. Ph.D: Next Generation Transcriptomics-based Precision Oncology Eytan Ruppin received his M.D. Read More...
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Bioinformatics
08/24/2022 - Precision oncology has made significant advances, mainly by targeting actionable mutations and fusion events involving cancer driver genes. Aiming to expand treatment opportunities, recent studies have begun to explore the utility of tumor transcriptome Read More...
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Bioinformatics
05/25/2022 - Dr. Peng Jiang of NCI’s Center for Cancer Research will discuss CytoSig , a software-based platform that is designed to provide both a database of target genes modulated by cytokines (i.e., proteins secreted Read More...
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Bioinformatics
06/04/2021 - Speaker: Rangan Sreenivas Sukumar Distinguished Technologist Hewlett Packard Enterprise (HPE) Abstract: In March of 2020, the “Force for Good” pledge of intellectual property to fight COVID-19 brought into action HPE products, resources and expertise to Read More...
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Bioinformatics
11/19/2019 - Methods for Characterizing the Activity of Mutational Processes in Cancer The cancer sequencing efforts of the past decade have revealed signatures of the mutational processes shaping cancer genomes. These mutational signatures provide a window Read More...
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Bioinformatics
02/21/2017 - This BTEP Workshop will cover the fundamentals and best practices of Exome-Seq analysis, including downstream interpretation of variants using a variety of in-house and NCI-licensed software solutions. There will be hands-on training on CCBR Read More...
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Bioinformatics
Try googling your problem or using some other search engine. rseek is an R specific search engine that searches several R related sites. If using Google or other major search engine directly, make sure you Read More...
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Bioinformatics
Data types are familiar in many programming languages, but also in natural language where we refer to them as the parts of speech, e.g. nouns, verbs, adverbs, etc. Once you know if a word Read More...
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Bioinformatics
Geneious Prime is a graphical user interface (GUI) based bioinformatics package that contains a suite of tools for molecular biology and Next Generation Sequencing analysis. {{Sdet}}{{Ssum}}Listing of Analysis Functions{{Esum}} Classic Computational Molecular Read More...
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Bioinformatics
There are many databases devoted to relating genes and gene products to pathways, processes, and other phenomenon. Again, the following is not meant to be a comprehensive list. Kyoto Encyclopedia of Genes and Genomes (KEGG) Read More...
Web Page
Bioinformatics
sessionInfo() R version 4.4.0 (2024-04-24) Platform: aarch64-apple-darwin20 Running under: macOS Sonoma 14.7.1 Matrix products: default BLAS: /Library/Frameworks/R.framework/Versions/4.4-arm64/Resources/lib/libRblas.0.dylib LAPACK: /Library/Frameworks/R.framework/Versions/4.4-arm64/Resources/lib/ Read More...
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Bioinformatics
There are many databases devoted to relating genes and gene products to pathways, processes, and other phenomenon and a multitude of organisms that may not have annotations in widely used databases (e.g., KEGG, GO). Read More...
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Bioinformatics
What is in the 22.gtf file? A gtf file is known as Genome Transfer File, which is essentially a tab delimited file (ie. columns in the file are separated by tab). It informs us of Read More...
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Bioinformatics
sessionInfo() R version 4.2.3 (2023-03-15) Platform: x86_64-apple-darwin17.0 (64-bit) Running under: macOS Big Sur ... 10.16 Matrix products: default BLAS: /Library/Frameworks/R.framework/Versions/4.2/Resources/lib/libRblas.0.dylib LAPACK: /Library/Frameworks/R.framework/Versions/4.2/Resources/lib/ Read More...
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Bioinformatics
The reference genome is a completely assembled sequence that we can compare other sequences to. For high throughput sequencing, we need the known sequences so that we can find out where in the genome each Read More...
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Bioinformatics
The reference genome is a completely assembled sequence (ie. the order in which the nucleotides are arranged is known). For high throughput sequencing, the known sequence help scientists find out where in the genome each Read More...
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Bioinformatics
The reference genome is a completely assembled sequence (ie. the order in which the nucleotides are arranged is known). For high throughput sequencing, the known sequence help scientists find out where in the genome each Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Research Festival The NIH Research Festival highlights the groundbreaking science and the vibrant NIH community driving our Read More...
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What is Xenium? Xenium is a high-resolution, imaging-based in situ spatial profiling technology from 10x Genomics that allows for simultaneous expression analysis of RNA targets (currently in range of 100’s) within the same tissue section. Read More...
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CREx News & Updates August 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGHLIGHTS Learn more about services from the NHLBI Read More...
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The Genomics Laboratory (formerly Laboratory of Molecular Technology) is an integrated, high-throughput molecular biology laboratory focusing on the development of genetics and genomics technologies, together with associated laboratory automation systems, data analysis, and information management Read More...
Bethesda, MD
Trans NIH Facility
The Neurorehabilitation and Biomechanics Research Section (also referred to as the NAB LAB) is a multidisciplinary group of highly qualified scientists, clinical and technical staff, and trainees with diverse backgrounds including medical, physical therapy, neuroscience Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New NIH Resource Spotlight The NIH Lab Managers Working Group have developed a new NIH-wide database of cold Read More...
Frederick, MD
Core Facility
The Genomics Technology Laboratory is an integrated, high-throughput molecular biology laboratory focusing on the development of genetics and genomics technologies, data analysis, and information management tools, in support of CCR Investigators. The laboratory develops integrated Read More...
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Bioinformatics
Learning Objectives This tutorial was designed to demonstrate common secondary analysis steps in a scRNA-Seq workflow. We will start with a merged Seurat Object with multiple data layers representing multiple samples. Throughout this tutorial we Read More...
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Bioinformatics
Objectives To understand some of the most basic features of the R language including: Creating R objects and understanding object types Using mathematical operations Using comparison operators Creating, subsetting, and modifying vectors By the end Read More...
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Bioinformatics
Learning Objectives Learn about data structures including factors, lists, data frames, and matrices. Load, explore, and access data in a tabular format (data frames) Learn to write out (export) data from the R environment Data Read More...
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Bioinformatics
Learning Objectives To understand: 1. the difference between R and RStudioIDE. 2. how to work within the RStudio environment including: creating an Rproject and Rscript navigating between directories using functions obtaining help how R can enhance data Read More...
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Bioinformatics
Note that we now have differential expression by transcripts and our first column contains the transcript IDs. But what genes do these transcripts map to? We will need to do some data wrangling to find Read More...
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Bioinformatics
Lesson 9: Reference genomes and genome annotations used in RNA sequencing Before getting started, remember to be signed on to the DNAnexus GOLD environment. Lesson 8 Review In Lesson 8, we learned about the basics of RNA sequencing, Read More...
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Bioinformatics
Lesson 9: Reference genomes and genome annotations used in RNA sequencing Before getting started, remember to be signed on to the DNAnexus GOLD environment. Lesson 8 Review In Lesson 8, we learned about the basics of RNA sequencing, Read More...
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Bioinformatics
Lesson 16: RNA sequencing review and classification based analysis Before getting started, remember to be signed on to the DNAnexus GOLD environment. Review In the previous classes, we learned about the steps involved in RNA sequencing Read More...
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Bioinformatics
Whether you are measuring mRNA expression, protein expression, DNA methylation, expressed miRNAs, protein binding to DNA or RNA, etc., you will likely end up with a list of genes or gene products from which you Read More...
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Bioinformatics
R basics Objectives : To understand some of the most basic features of the R language including: Creating R objects and understanding object types Using mathematical operations Using comparison operators Creating, subsetting, and modifying vectors By Read More...
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Bioinformatics
Introduction to R and RStudio IDE Objectives To understand: 1. the difference between R and RStudioIDE. 2. how to work within the RStudio environment including: creating an Rproject and Rscript navigating between directories using functions obtaining help 3. Read More...
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Bioinformatics
Data frames Objectives To be able to load, explore, and access data in a tabular format. To this end, students should understand the following: 1. how to import and export data 2. how to create, summarize, and Read More...
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Bioinformatics
06/19/2017 - Harvesting the Wealth of TCGA Data The Cancer Genome Atlas (TCGA) is a large-scale study that has catalogued genomic data accumulated from more than 20 different types of cancer including mutations, copy number variation, mRNA Read More...
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Bioinformatics
12/20/2016 - ABOUT THE COURSE R is a freely available language and environment for statistical computing and graphics which provides a wide variety of statistical and graphical techniques: linear and nonlinear modelling, statistical tests, time series Read More...
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Bioinformatics
11/22/2016 - ABOUT THE COURSE R is a freely available language and environment for statistical computing and graphics which provides a wide variety of statistical and graphical techniques: linear and nonlinear modelling, statistical tests, time series Read More...
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Bioinformatics
11/09/2015 - A Short Course in R for Biologists "A Short Course in R for Biologists" is a two-day course given in four three-hour sessions entitled: Introduction to R, Introduction to Bioconductor, Introduction to Read More...
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Bioinformatics
10/22/2015 - /* element spacing */ p, pre { margin: 0em 0em 1em; } /* center images and tables */ img, table { margin: 0em auto 1em; } p { text-align: justify; } tt, code, pre { font-family: 'DejaVu Sans Mono', 'Droid Sans Mono', 'Lucida Console', Consolas, Read More...
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Bioinformatics
01/29/2015 - /* element spacing */ p, pre { margin: 0em 0em 1em; } /* center images and tables */ img, table { margin: 0em auto 1em; } p { text-align: justify; } tt, code, pre { font-family: 'DejaVu Sans Mono', 'Droid Sans Mono', 'Lucida Console', Consolas, Read More...