Search Results for: workflows

06/28/2023 - This talk will focus on the FAIR principles and the other aspects of data and workflow management we believe are necessary for reproducible research. Mr. Smith will discuss how the Arvados platform helps you & Read More...

This is part II of the article highlighting nf-core pipelines and specifically addresses the use of these pipelines in the DNAnexus cloud environment. Part I of the article can be found in the October 2023 topic Read More...

12/07/2023 - This webinar will discuss and demonstrate experimental design considerations in variant analysis, including the origins of tissue samples (germline vs. somatic), whole exome (WES) or whole-genome sequencing (WGS), sample sizes and statistical power, quality Read More...

10/08/2021 - Dr. Pjotr Prins and Arun Isaac will present their Concise Common Workflow Language (CCWL). CCWL makes code reusable and adaptable across a variety of software and hardware environment while following FAIR+ (Findable, Accessible, Interoperable, Read More...

03/13/2020 - Dr. Rommie Amaro from University of California, San Diego covers what scientific workflows and pipeline are, how they can be useful or even critical to science and big data management and presents relevant examples Read More...

03/12/2020 - Dr. Rommie Amaro from University of California, San Diego covers what scientific workflows and pipeline are, how they can be useful or even critical to science and big data management and presents relevant examples Read More...

03/10/2020 - Dr. Rommie Amaro from University of California, San Diego covers what scientific workflows and pipeline are, how they can be useful or even critical to science and big data management and presents relevant examples Read More...

03/09/2020 - Dr. Rommie Amaro from University of California, San Diego covers what scientific workflows and pipeline are, how they can be useful or even critical to science and big data management and presents relevant examples Read More...

nf-core is a community effort to generate a curated set of standardized, best-practice, reproducible, documented, NGS analysis pipelines. All these workflows are built using the versatile workflow manager, Nextflow , and have been released under the Read More...

09/11/2020 - By Avi Ma'ayan, Director of the Mount Sinai Center for Bioinformatics Daniel Clarke, Senior Data Scientist and Nicole Moiseyev, Summer Scholar Department of Pharmacological Sciences, Mount Sinai Center for Bioinformatics, Icahn School of Read More...

12/11/2024 - This session of the BTEP Coding Club introduces NIH CloudLab, a free 90-day sandbox environment partnered with AWS, Google Cloud, and Azure, and demonstrates how to run Nextflow pipelines, a powerful workflow management system Read More...

11/13/2024 - This webinar will provide an overview of the generative artificial intelligence (AI) services across three major cloud service providers (CSPs) and the steps to follow for setting up AI chatbots in cloud environments with Read More...

06/30/2022 - Experimental Design Considerations in Variant Analysis Germline vs Somatic WGS vs WES Sample sizes and statistical power QC, variant annotation, and analysis considerations Beyond GATK! A survey of variant calling tools The  actual  Best Read More...

04/23/2020 - Within the last decade, Dr. Albert has served as the lead developer of various well-known bioinformatics related, web-based platforms such as Galaxy and Biostars. During the same time, he has participated in strengthening the Read More...

03/19/2020 - THIS EVENT HAS BEEN CANCELLED Within the last decade, Dr. Albert has served as the lead developer of various well-known bioinformatics related, web-based platforms such as Galaxy and Biostars. During the same time, he Read More...

https://bioinformatics.ccr.cancer.gov/ccbr/education-training/nidap-training/

In this session of the BTEP Coding Club, Zelaikha Yosufzai (NIH/CIT), Bioinformatician with the NIH STRIDES Initiative, introduced NIH CloudLab, a free 90-day sandbox environment partnered with AWS, Google Cloud, and Azure, and showed Read More...

Bioconductor is a repository for R packages related to biological data analysis, primarily bioinformatics and computational biology, and as such it is a great place to search for -omics packages and pipelines. Bioconductor packages fit Read More...

02/23/2026 - This one and a half hour online training equips participants with powerful data wrangling techniques using R and the tidyverse ecosystem. The tidyverse is a cohesive ecosystem of R packages designed to make data Read More...

02/19/2026 - This session introduces NIH STRIDES and Cloud Lab resources for bioinformatics and generative AI workflows in the cloud. Participants will tour key tutorial libraries, including the STRIDES Cloud Lab GitHub repositories (AWS, GCP, Azure Read More...

10/09/2025 - This one-hour online training introduces attendees to modeling and simulation of biological systems using MATLAB’s SimBiology and BioPipeline Designer toolboxes. SimBiology is a versatile toolbox for modeling, simulating, and analyzing dynamic Read More...

04/10/2025 - This one hour online training introduces participants to the tools and techniques for analyzing and quantifying microscopy images using MATLAB’s low-code algorithms. Participants will learn how to preprocess images, segment regions Read More...

01/22/2025 - Join us for a one-hour talk investigating tumor signatures in the BRCA dataset by utilizing the CCBR Single-Cell RNA-seq Workflow on NIDAP. This talk will take you through an analysis of a publicly available Read More...

Single cell RNA sequencing (scRNA-Seq) is becoming increasingly more common in biomedical research, but what is scRNA-Seq? How does it differ from other transcriptomic approaches (e.g., bulk RNA-Seq), and what are the potential applications, Read More...

Introduction to single cell RNA-Seq Single cell RNA sequencing (scRNA-Seq) is becoming increasingly more common in biomedical research, but what is scRNA-Seq? How does it differ from other transcriptomic approaches (e.g., bulk RNA-Seq), and Read More...

04/10/2024 - Single cell RNA sequencing (scRNA-Seq) is becoming increasingly more common in biomedical research, but what is scRNA-Seq? How does it differ from other transcriptomic approaches (e.g., bulk RNA-Seq), and what are the potential Read More...

02/27/2024 - This session will cover what are containers, and why and how to use them in your Bioinformatics workflows. We will review best practices, basic commands, and useful resources. This session is geared towards beginners.& Read More...

02/22/2024 - Join us for an introduction to bioinformatics resources for NCI CCR researchers.  Featuring:  NIH Bioinformatics Calendar Programming Classes (R, Unix, Python) Class documentation Website resources working on high performance compute cluster (Biowulf/Helix) Next-Gen Read More...

R is a particularly great resource for statistical analyses, plotting, and report generating. wide use = functions and packages covering a broad range of topics. CRAN has 20,000 + packages Bioconductor (v 3.18) includes 2,266 software packages, 429 experiment data packages, 920 Read More...

R is a particularly great resource for statistical analyses, plotting, and report generating. The fact that it is widely used means that users do not need to reinvent the wheel. There is a package available Read More...

Bioconductor is both an open source project and repository for R packages related to the analysis of biological data, primarily bioinformatics and computational biology, and as such it is a great place to search for Read More...

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Image Analysis Capabilities: Custom Development Software Supported Software Platforms Arivis Vision 4D Arivis is software for image processing, analysis, and display for working with multi-channel 2D, 3D and 4D images of almost unlimited size independent Read More...

12/02/2026 - Partek Flow is a point-and-click platform for building analysis workflows for Next Generation Sequences (NGS), including DNA, bulk and single-cell RNA, spatial transcriptomics, ATAC, and ChIP, helping scientists avoid the steep learning curve of Read More...

10/14/2026 - Partek Flow is a point-and-click platform for building analysis workflows for Next Generation Sequences (NGS), including DNA, bulk and single-cell RNA, spatial transcriptomics, ATAC, and ChIP, helping scientists avoid the steep learning curve of Read More...

08/19/2026 - Partek Flow is a point-and-click platform for building analysis workflows for Next Generation Sequences (NGS), including DNA, bulk and single-cell RNA, spatial transcriptomics, ATAC, and ChIP, helping scientists avoid the steep learning curve of Read More...

06/18/2026 - Partek Flow is a point-and-click platform for building analysis workflows for Next Generation Sequences (NGS), including DNA, bulk and single-cell RNA, spatial transcriptomics, ATAC, and ChIP, helping scientists avoid the steep learning curve of Read More...

03/06/2026 - This 45-minute online Lunch and Learn training will help attendees develop their own customized strategy for responsibly incorporating generative artificial intelligence (AI) tools, such as ChatGPT, into their workflows.  By the end Read More...

02/18/2026 - Partek Flow is a point-and-click platform for building analysis workflows for Next Generation Sequences (NGS), including DNA, bulk and single-cell RNA, spatial transcriptomics, ATAC, and ChIP, helping scientists avoid the steep learning curve of Read More...

02/03/2026 - Note: It is recommended to take the Getting Started with AI Productivity Double Feature class prior to this. Unlock the power of your new personal assistant with our comprehensive overview class. Learn how to Read More...

01/22/2026 - Attend this webinar to learn more about XNAT Scout—a new extension of the XNAT imaging informatics platform that’s designed to close the gap between artificial intelligence (AI) model development and clinical deployment. Read More...

01/21/2026 - This one-hour online training offers an overview of the NIH-sponsored Generalist Repository Ecosystem Initiative (GREI) (Dataverse, Dryad, Figshare, Mendeley Data, Open Science Framework, Vivli, and Zenodo), and the role of participating in these repositories Read More...

01/16/2026 - This one-hour online training introduces applying data science and artificial intelligence (AI) techniques to signals and time-series datasets using MATLAB. The training will cover the entire AI pipeline, from signal exploration to deployment. Participants Read More...

01/15/2026 - Gil Kanfer, PhD, of the NCI CCR High-Throughput Imaging Facility (HiTIF), in the Laboratory of Receptor Biology and Gene Expression (LRBGE) , will present the spatial biology analysis stack HiTIF is building to support Center Read More...

12/10/2025 - Partek Flow enables scientists to construct analysis workflows for multi-omics sequencing data including DNA, bulk and single cell RNA, spatial transcriptomics, ATAC and ChIP. It is a point-and-click software suitable for those who wish Read More...

11/20/2025 - This one-hour online training offers an overview of the NIH-sponsored Generalist Repository Ecosystem Initiative (GREI) (Dataverse, Dryad, Figshare, Mendeley Data, Open Science Framework, Vivli, and Zenodo), and the role of participating in these repositories Read More...

11/06/2025 - This 45-minute online Lunch and Learn training will help attendees develop their own customized strategy for responsibly incorporating generative artificial intelligence (AI) tools, such as ChatGPT, into their workflows. By the end of this Read More...

10/08/2025 - This one-hour online training equips participants with powerful data wrangling techniques using R and the tidyverse ecosystem. The tidyverse is a cohesive ecosystem of R packages designed to make data science workflows more intuitive Read More...

09/23/2025 - This one-hour online training covers various aspects of sharing code using MATLAB community tools like File Exchange and GitHub. Well-documented methods and workflows enable reproducible research by helping scientists follow each other& Read More...

09/22/2025 - This one-hour online training introduces applying data science and artificial intelligence (AI) techniques to signals and time-series datasets using MATLAB. The training will cover the entire AI pipeline, from signal exploration to deployment. Participants Read More...

09/11/2025 - This interactive 1.5-hour workshop introduces participants to prompt engineering for effective AI communication. Through engaging, collaborative activities, attendees will learn to design clear, specific prompts that yield high-quality AI outputs for both technical and Read More...

09/11/2025 - This interactive 1.5-hour workshop introduces participants to prompt engineering for effective AI communication. Through engaging, collaborative activities, attendees will learn to design clear, specific prompts that yield high-quality AI outputs for both technical and Read More...

08/25/2025 - This one hour and half online training is designed for those who create reproducible projects and also want to extend the basics of R Markdown and apply those skills in  Quarto . Quarto Read More...

06/18/2025 - This 45-minute online Lunch and Learn training will help attendees develop their own customized strategy for responsibly incorporating generative artificial intelligence (AI) tools, such as ChatGPT, into their workflows.  By the end Read More...

This archive contains past and present issues of the  BTEP BioInformatics Bulletin. The BTEP Bioinformatics Bulletin features select upcoming bioinformatics events offered across NIH and is distributed monthly via email to the Center Read More...

03/19/2025 - This one hour and a half online training provides an accessible introduction to artificial intelligence (AI) using MATLAB. Designed for beginners, the session covers fundamental concepts in AI and machine learning, introduces intuitive tools Read More...

01/22/2025 - This three hour online training covers QIAGEN’s CLC Genomics Workbench enables researchers to analyze NGS data without the use of command line and is a powerful tool for determining differential expression. Read More...

11/19/2024 - Partek Flow enables scientists to construct analysis workflows for multi-omics sequencing data including DNA, bulk and single cell RNA, spatial transcriptomics, ATAC and ChIP. It is a point-and-click software hosted on Biowulf, the NIH Read More...

Cancer research is a complex and data-intensive field. Cloud computing offers a powerful solution for researchers to store, analyze, and share large datasets efficiently. In this month’s topic spotlight, we will explore cloud resources Read More...

09/19/2024 - This hour and-half online training discusses how MATLAB enhances data analysis and visualization for technical professionals who typically use Excel. It highlights MATLAB's advantages, such as access to pre-built mathematical and analysis functions, Read More...

Congratulations, your experiments have been completed and you have a large amount of data. Now, it’s time to analyze these data. But where do you begin? How can you gain the most meaning from Read More...

08/27/2024 - This 45-minute online Lunch and Learn training will help attendees develop their own customized strategy for responsibly incorporating generative artificial intelligence (AI) tools, such as ChatGPT, into their workflows.  By the end Read More...

08/23/2024 - In this webinar, Dr. Carey will provide an introduction to Bioconductor for genomic data science.   Bioconductor.org enters its third decade as an NHGRI/NCI-funded resource for many aspects of genomic data Read More...

07/24/2024 - As a cancer researcher, did you know that  data sharing  is now required by many funding agencies and journals? Join NCI CBIIT’s  Dr. Jill Barnholtz-Sloan & Read More...

07/24/2024 - Partek Flow enables scientists to construct analysis workflows for multi-omics sequencing data including DNA, bulk and single cell RNA, spatial transcriptomics, ATAC and ChIP. It is hosted on Biowulf, the NIH high performance computing Read More...

06/20/2024 - Dr. Irizarry will share findings demonstrating limitations of current workflows that are popular in single cell RNA-Seq data analysis. Specifically, he will describe challenges and solutions to dimension reduction, cell-type classification, and statistical significance Read More...

05/29/2024 - This talk will cover a scRNA-seq workflow available to NCI researchers on NIDAP. NIDAP, the NIH Integrated Data Analysis Platform, is a cloud-based and collaborative data aggregation and analysis platform that hosts user-friendly bioinformatics Read More...

05/29/2024 - Dear Colleagues,   As machine learning permeates across biomedical research, achieving optimal accuracy demands more than just model deployment.  Join us for a webinar where we explore post-processing techniques designed to Read More...

Seurat is an R package designed for QC, analysis, and exploration of single-cell RNA-seq data. Seurat aims to enable users to identify and interpret sources of heterogeneity from single-cell transcriptomic measurements, and to integrate diverse Read More...

Josh Meyer, bioinformatics analyst (CCBR), will cover a scRNA-seq workflow available to NCI researchers on NIDAP . NIDAP, the NIH Integrated Data Analysis Platform, is a cloud-based and collaborative data aggregation and analysis platform that hosts Read More...

R is both a computational language and environment for statistical computing and graphics. It is open-source and widely used by scientists, not just bioinformaticians. Base packages of R are built into your initial installation, but Read More...

The CCBR Single-cell RNA-seq Workflow on NIDAP Josh Meyer, bioinformatics analyst (CCBR), will cover a scRNA-seq workflow available to NCI researchers on NIDAP . NIDAP, the NIH Integrated Data Analysis Platform, is a cloud-based and collaborative Read More...

Who can you contact with questions? NCI CCR Single Cell Analysis Facility (SCAF) provides single cell support to NCI-CCR Researchers. NCI CCR Bioinformatics Training and Education Program (BTEP) provides bioinformatics training support. Contact BTEP via Read More...

Additional Resources BTEP scRNA-Seq FAQs Training modules available on Github Orchestrating Single Cell Analysis with Bioconductor Single Cell Best Practices 2023 BTEP Single Cell Annotation Seminar Series Event recordings are located in the BTEP Video Archive . Read More...

In Seurat (since version 4), differential analysis requires a preprocessing step to appropriately scale the normalized SCTransform assay across samples: adp = PrepSCTFindMarkers(adp) Found 8 SCT models. Recorrecting SCT counts using minimum median counts: 8146 As covered earlier, Read More...

05/15/2024 - In this one-hour webinar, you'll get a demonstration of DNASTAR Lasergene Software. DNASTAR offers software solutions for molecular biology, protein analysis, and genomics. This presentation will focus on an overview of the applications Read More...

04/22/2024 - Dear Colleagues,    In this webinar, you'll get an introduction to XNAT. XNAT is an open-source platform for managing, processing, and sharing medical imaging and related data in research settings. & Read More...

03/27/2024 - This half-day, virtual workshop features representatives from NCI cancer data cloud resources, including the  NCI Cancer Research Data Commons  (CRDC),  Institute for Systems Biology Cancer Gateway in the Read More...

03/04/2024 - This class is designed for those who want to extend the basics of R Markdown and apply those skills in Quarto. Quarto is an open-source scientific and technical publishing system that offers multilingual programming Read More...

The Bioinformatics Training and Education Program is happy to announce open office hours. The BTEP team will be available virtually via Microsoft Teams to help you with your bioinformatics questions / problems from 1 PM to 3 PM , Read More...

readRDS("./data/diffexp_results_edger_airways.rds") |> #read data select(transcript, logFC, FDR) |> #select columns of interest filter(transcript == "TSPAN6" | transcript=="DPM1" ) |> #filter ggplot(aes(x= Read More...

Bioconductor packages are divided into four types: software annotation data experiment data workflows. Software packages themselves can be subdivided into packages that provide infrastructure (i.e., classes) to store and access data, and packages that Read More...

::: {.cell} readRDS ( "./data/diffexp_results_edger_airways.rds" ) |> #read data select ( transcript , logFC , FDR ) |> #select columns of interest filter ( transcript == "TSPAN6" | transcript == "DPM1" ) |> #filter ggplot ( aes ( Read More...

Reproducibility in science means being able to generate the same experimental / analytical results with a high degree of reliability. This is necessary for research validation, scientific and public trust, innovation, and collaboration. Reproducibility is not Read More...

01/26/2024 - The RDI SIG is a trans-institute group whose investigators apply informatics approach to curate, harmonize, standardize, and analyze biomedical data obtained from a variety of resources (i.e., gene sequences, bioassays, electronic health records Read More...

Work through DNAnexus? Find a nice cancer data set for 16S and shotgun Divide into two workshops or courses? Course structure or workshop structure? Amplicon processing and analysis (5 week course) (4 weeks) 1. Talk by Greg Caparaso? 1. Read More...

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Most BTEP courses include detailed course materials including lesson content, additional resources, and lesson associated data. These course materials are listed here so that learners can easily return to and review concepts taught in class Read More...

Long read sequencing was recently named 2022’s method of the year by Nature Methods . Long read sequencing technologies, those that generate sequence reads with lengths of 10s of kilobases or longer have several advantages over Read More...

Listed below are the video recordings of past BTEP events (classes, seminars, workshops). Videos are hosted on various servers and may play slightly differently. Some videos may be downloaded for local viewing. Recorded Videos of Read More...

What is bioinformatics? Bioinformatics integrates biology, statistics, and computer science to develop and apply theory, methods, and tools for the collection, storage, and analysis of biological and related data. Bioinformatics plays a critical role in Read More...

Partek Flow enables scientists to build comprehensive workflows for analyzing multi-omics high throughput sequencing data including DNA and variant calling, bulk and single cell modalities for RNA, ChIP, and ATAC, spatial transcriptomics, CITE, and immune Read More...

This lesson provides an introduction to R in the context of single cell RNA-Seq analysis with Seurat. Learning Objectives Learn about options for analyzing your scRNA-Seq data. Learn about resources for learning R programming. Learn Read More...

1. Introduction and Learning Objectives This tutorial has been designed to demonstrate common secondary analysis steps in a scRNA-Seq workflow. We will start with a merged Seurat Object with multiple data layers representing multiple samples that Read More...

The Advanced Biomedical Computational Science (ABCS) group focuses on applications of bioinformatics, computational and data science, and artificial intelligence to support NCI researchers. ABCS provides: • Subject matter expertise in genomics, proteomics, and imaging. • Machine learning/ Read More...

Objectives To explore Bioconductor, a repository for R packages related to biological data analysis. To learn about options for report generation with R: RMarkdown and Quarto. Introducing Bioconductor Bioconductor is both an open source project Read More...

Welcome! Welcome to the R Introductory Series! Who: Novices and beginners\ What: A course series introducing R and RStudio. This course will introduce the foundational skills necessary to begin to analyze and visualize data in Read More...

Learning Objectives To understand: 1. the difference between R and RStudioIDE. 2. how to work within the RStudio environment including: creating an Rproject and Rscript navigating between directories using functions obtaining help how R can enhance data Read More...

In this lesson, attendees will learn how to transform, summarize, and reshape data using functions from the tidyverse. Learning Objectives Continue to wrangle data using tidyverse functionality. To this end, you should understand: how to Read More...

In this lesson, attendees will learn how to transform, summarize, and reshape data using functions from the tidyverse. Learning Objectives Continue to wrangle data using tidyverse functionality. To this end, you should understand: how to Read More...

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