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Search Results for: HSP 110 / GP 100 Chaperone

Total Results Found: 127

Data Visualization with R: Question 1

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Bioinformatics

Let's check out the structure of the data. {{Sdet}} Possible Solution{{Esum}} str(mtcars) ## 'data.frame': 32 obs. of 11 variables: ## $ mpg : num 21 21 22.8 21.4 18.7 18.1 14.3 24.4 22.8 19.2 ... ## $ cyl : num 6 6 4 6 8 6 8 4 4 6 ... ## $ disp: num 160 160 108 258 360 ... ## $ hp : num 110 110 93 110 175 105 245 62 95 123 ... ## $ drat: num 3.9 3.9 3.85 3.08 3.15 2.76 3.21 3.69 3.92 3.92 ... ## $ wt : num 2.62 2.88 2.32 3.21 3.44 ... ## $ qsec: num 16.5 17 18.6 19.4 17 ... ## $ vs : Read More...

Biopharmaceutical Development Program (BDP)
Frederick, MD

Collaborative

The Biopharmaceutical Development Program (BDP) provides resources for the development of investigational biological agents. The BDP supports feasibility through development and Phase I/II cGMP manufacturing plus regulatory documentation.The BDP was established in 1993. We Read More...

Data Visualization with R: Scaling

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Bioinformatics

Prior to sending our data into the heatmap generating algorithm, it is a good idea to sacle. There are several reasons for doing this Variables in the data might not have the same units, thus Read More...

Data Visualization with R: Scaling

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Bioinformatics

Prior to sending our data into the heatmap generating algorithm, it is a good idea to sacle. There are several reasons for doing this Variables in the data might not have the same units, thus Read More...

R Introductory Series: The ggplot2 template

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Bioinformatics

The following represents the basic ggplot2 template: ggplot(data = ) + (mapping = aes()) We need three basic components to create a plot: the data we want to plot , geom function(s) , and mapping aesthetics . Notice the + symbol Read More...

Microbiome Analysis with QIIME2: Meet our presenter

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Bioinformatics

Greg Caporaso, PhD Professor at Northern Arizona University A microbiome expert with 100+ related publications Lead developer of the QIIME 2 Platform Visit his lab website at https://caporasolab.us

Data Wrangling with R: Things to note

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Bioinformatics

R doesn't care about spaces in your code. However, it can vastly improve readability if you include them. For example, "thisissohardtoread" but "this is fine". You can use tab completion Read More...

Data Visualization with R: Add custom axes labels

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Bioinformatics

#Plot ggplot(pcaData) + aes(PC1, PC2, color = Species, shape = Species) + geom_point(size = 2) + coord_fixed() + xlab("PC1: 73%")+ #x axis label text ylab("PC2: 23%") # y axis label text Automating % Variance in axis Read More...

Data Visualization with R: row-wise scaling

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Bioinformatics

Scaling is important during cluster analysis because it reduces the influence that variables with high magnitude values will have on distance. (https://medium.com/analytics-vidhya/why-is-scaling-required-in-knn-and-k-means-8129e4d88ed7). A common method for scaling is Read More...

NIH Clinical Center Positron Emission Tomography (PET)
Bethesda, MD

Core Facility

Trans NIH Facility

The PET Department, CC, functions as a core facility that supports basic, translational, and clinical research using PET. It is a vertically integrated facility, with resources to produce positron-emitting radionuclides, manufacture PET radiopharmaceuticals in a Read More...

Newsletter Archive

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NIH AgingResearchBiobank
Bethesda, Maryland

Core Facility

Repositories

The AgingResearchBiobank was officially launched in January 2019 with a mission to provide a state-of-the-art inventory system for the storage, maintenance, and distribution of de-identified biospecimens and associated phenotypic, clinical, and imaging data from numerous NIA-funded Read More...

Data Wrangling with R: mutate()

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Bioinformatics

mutate() adds new variables and preserves existing ones; transmute() adds new variables and drops existing ones. New variables overwrite existing variables of the same name. --- dplyr.tidyverse.org Let's create a column in Read More...

Microbiome Analysis with QIIME2: QIIME2 Introduction

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Bioinformatics

Lesson 1: Toward fully reproducible microbiome multi-omics bioinformatics with QIIME 2 Lesson 1 does not include a hands on component, but rather includes an introduction to QIIME2 by guest speaker, Dr. Greg Caporaso, a leading developer of the Read More...

Data Wrangling with R: Group_by and summarize

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Bioinformatics

There is an approach to data analysis known as "split-apply-combine", in which the data is split into smaller components, some type of analysis is applied to each component, and the results are combined. Read More...

Bioinformatics for Beginners 2022: To get an overview of alignments in a BAM file

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Bioinformatics

samtools flagstat SRR1972739.bwa.bam produces this 20740 + 0 in total (QC-passed reads + QC-failed reads) 0 + 0 secondary 740 + 0 supplementary 0 + 0 duplicates 15279 + 0 mapped (73.67% : N/A) 20000 + 0 paired in sequencing 10000 + 0 read1 10000 + 0 read2 14480 + 0 properly paired (72.40% : N/A) 14528 + 0 with itself and mate mapped 11 + 0 singletons (0.05% : N/ Read More...

Bioinformatics for Beginners 2022: To get an overview of alignments in a BAM file

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Bioinformatics

samtools flagstat SRR1972739.bwa.bam produces this 20740 + 0 in total (QC-passed reads + QC-failed reads) 0 + 0 secondary 740 + 0 supplementary 0 + 0 duplicates 15279 + 0 mapped (73.67% : N/A) 20000 + 0 paired in sequencing 10000 + 0 read1 10000 + 0 read2 14480 + 0 properly paired (72.40% : N/A) 14528 + 0 with itself and mate mapped 11 + 0 singletons (0.05% : N/ Read More...

Bioinformatics for Beginners 2022: Things to consider:

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Bioinformatics

STAR 2-pass mode --sjdbGTFfile is the path to the file with annotated transcripts in standard GTF format, STAR extracts splice junctions from this file, improves accuracy of mapping. Using annotations is highly recommended whenever they Read More...

March Data Sharing and Reuse Seminar

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Bioinformatics

03/10/2023 - Dr. Melissa Haendel and Dr. Jakob Seidlitz will present "2022 DataWorks! Grand Prize Winners: Innovations in Data Sharing and Reuse" at the monthly Data Sharing and Reuse Seminar on March 10, 2023 at 12 p.m. Read More...

Spatial Biology

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Employing spatial biology techniques enables acquisition of transcript and protein data from intact tissue sections, and in turn, spatial distribution information and cellular interaction patterns are revealed.

Xenium Spatial Profiling Technology

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What is Xenium? Xenium is a high-resolution, imaging-based in situ spatial profiling technology from 10x Genomics that allows for simultaneous expression analysis of RNA targets (currently in range of 100’s) within the same tissue section. Read More...

CREx Newsletter Archive

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Isothermal Titration Calorimetry (ITC) – iTC200

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Back Services: Biophysics Facility offers ITC calorimeters as open-access instruments.  First-time users must complete a short training session before gaining access to the instrument reservation calendar.  Training includes performing a test experiment and Read More...

NIMH Human Brain Collection Core (HBCC)
Bethesda, MD

Core Facility

Repositories

The mission of Human Brain Collection Core (HBCC) within the National Institute of Mental Health, Division of Intramural Programs (NIMH IRP) is to conduct and support research on brain and behavior, with the goal of Read More...

Antibody Engineering Program
Bethesda, MD

Collaborative

The Antibody Engineering Program (AEP) is located at the Laboratory of Molecular Biology, which is part of the Center for Cancer Research (CCR), an intramural program at the National Cancer Institute (NCI). AEP focuses on Read More...

Technology Video Library

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The OSTR offers cutting-edge technology platforms to the CCR scientific community through centralized facilities. The videos accessed through this page are designed to introduce the various scientific methodologies OSTR makes available through the cores on Read More...

Visium Spatial Gene Expression Technology

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What is Visium FFPE v2 with CytAssist? Visium FFPE v2 is sequencing-based spatial profiling technology developed by 10x Genomics. This assay can take mouse or human tissue sections on normal glass slides as input and Read More...

NCI Synthetic Biologics Core
Frederick, MD

Core Facility

The research conducted within the Synthetic Biologics Core (SBC) Facility has a dual role: Generate chemical biology tools and drug candidates for molecular targets identified by NCI research groups, Develop novel effective methods and tools Read More...

Mass Photometer (MP) – Refeyn OneMP

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Back Services: Biophysics Facility offers MP as an open-access instrument.  First-time users must complete a short training session before gaining access to the instrument training calendar.  Training includes mass distribution analysis of a Read More...

Multi-Angle Light Scattering (MALS)

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Back Services: We offer a limited sample processing service using standard SEC-MALS and FFF protocols.  This service is intended for the occasional users of this system.  Researchers who expect to use this instrument Read More...

Microfluidic Diffusion Sizing (MDS) - Fluidity One-M

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Back Services: Biophysics Facility offers MDS as an open-access instrument. First-time users must complete a short training session before gaining access to the instrument reservation calendar. Training includes the KD determination of a standard molecular Read More...

Bio-Layer Interferometry (BLI) - Octet RED96

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Back Services: Biophysics Facility offers Octet as an open-access instrument.  First-time users must complete a short training session before gaining access to the instrument reservation calendar.  Training includes a full analysis of a Read More...

Pan-Microbial Serology Facility (PMSF)
Bethesda, MD

Collaborative

The Pan-Microbial Serology Facility (PMSF) is part of the Center for Cancer Research (CCR) at the National Cancer Institute (NCI). The PMSF focuses on determining individualized pan-microbial immune profiles associated with human diseases including immunological Read More...

CCR Genomics Core
Bethesda, MD

Core Facility

The CCR Genomics Core is located in Building 41 on the NIH Bethesda campus. The primary goal of the Core is to provide investigators from CCR/NCI and other NIH Institutes access to genomic technologies and Read More...

NIH Intramural Sequencing Center (NISC)
Rockville, MD

Trans NIH Facility

NISC’s role within NHGRI, and more broadly across NIH, aims to advance genome sequencing and its many applications, with a goal not simply to produce sequence data, but to produce the infrastructure required to Read More...

Microbiome Analysis with QIIME2: Beta Diversity

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Bioinformatics

Lesson 6 . Learning Objectives Introduce several beta diversity metrics Discover different ordination methods Learn about statistical methods that are applicable Beta diversity Beta diversity is between sample diversity. This is useful for answering the question, how Read More...

Bioinformatics for Beginners 2022: 18. BLAST copy

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Bioinformatics

This page uses content directly from the Biostar Handbook by Istvan Albert. Remember to activate the bioinformatics environment and create a directory for today's work. conda activate bioinfo mkdir blast cd blast What is Read More...

Bioinformatics for Beginners 2022: B4b 2022 rnaseq jw

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Bioinformatics

This page uses content directly from the Biostar Handbook by Istvan Albert. Obtain RNA-seq test data. The test data consists of two commercially available RNA samples: Universal Human Reference (UHR) and Human Brain Reference (HBR) . Read More...

Data Visualization with R: Going beyond Excel

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Bioinformatics

Excel is a great program for visualizing and manipulating small data sets. However, it isn't great for working with "big data", and resulting plots are generally not publishable. Learning R and associated Read More...

Data Visualization with R: Lesson5

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Bioinformatics

Visualizing clusters with heatmaps Objectives Introduce the heatmap and dendrogram as tools for visualizing clusters in data. Learn how to work with the package pheatmap . Learn how to save a non-ggplot2 plot. Introduce ggplotify to Read More...

Data Visualization with R: Save as an R object

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Bioinformatics

Below, we assign the heatmap to the R object hm_ph. hm_ph {"x":{"data":[{"x":[4.875,2.875,null,2.875,2.875,null,2.875,1.75,null,1.75,1.75,null,1.75,1,null,1,1,null,1.75,2.5,null,2.5,2.5,null,2.5,2,null,2,2,null,2.5,3,null,3,3,null,2.875,4,null,4,4, Read More...