Frederick, MD
Core Facility
NCI LASP Genome Modification Core (GMC) is a CCR-dedicated facility that provides advice, training, and reagents to NCI scientists seeking to utilize CRISPR and other nucleases to generate genome modifications in primary cells, cell lines, Read More...
Rockville, MD
Collaborative
We are a bioinformatics team within the Center for Biomedical Informatics and Information Technology’s (CBIIT’s) Cancer Informatics Branch (CIB)—soon to be referred to as the Informatics and Data Science (IDS) Program. Headed Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx User Survey The CREx Team is carrying out a CREx User Survey. If you haven’t Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx User Survey The CREx Team is carrying out a CREx User Survey. We would greatly appreciate Read More...
Bethesda, MD
Collaborative
The Mass Spectrometry Unit of the Collaborative Protein Technology Resource uses mass spectrometry for the study of proteins. We perform collaborative experiments with CCR researchers in areas such as: interactomes, quantitative global proteome analyses, and Read More...
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Mass Spectrometry Section of the Collaborative Protein Technology Resource (Bldg. 37) Core Capabilities: Identification of proteins in complexes, organelles, subcellular fractions, or fluids. Global relative protein quantitation. Quantitation by isotopic labeling of cells in culture (SILAC) Read More...
Bethesda, MD
Collaborative
The Spatial Imaging Technology Resource (formerly the Nanoscale Protein Analysis Section of the Collaborative Protein Technology Resource or CPTR) provides expertise and service in state-of-the-art protein analysis technologies to advance CCR research in basic discovery Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx Program Manager The CREx Team is happy to announce Deepika Velampati as the new CREx Program Read More...
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CREx News & Updates October 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGLIGHTS Learn more about services from the CPTR Read More...
Frederick, MD
Core Facility
Protein and Metabolite Characterization Core (PMCC), formerly known as the Protein Characterization Lab (PCL), offers various technologies to CCR investigators to characterize proteins and metabolites. The core develops and applies state-of-the-art analytical technologies, primarily mass Read More...
Bethesda, MD
Trans NIH Facility
The Biomedical Engineering and Physical Science (BEPS) shared resource supports NIH’s intramural basic and clinical scientists on applications of engineering, physics, imaging, measurement, and analysis. BEPS is centrally located on the main NIH campus Read More...
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Back Services: Biophysics Facility offers ITC calorimeters as open-access instruments. First-time users must complete a short training session before gaining access to the instrument reservation calendar. Training includes performing a test experiment and Read More...
Rockville, MD
Core Facility
The Chemistry and Synthesis Center (CSC) of the National Heart, Lung, and Blood Institute (NHLBI) provides IRP scientists with targeted imaging probes and chemical tools that help accelerate cell-based assays, in vivo imaging studies, and Read More...
Frederick, MD
Collaborative
In order to meet increasing demands from both NIH intramural and extramural communities for access to a small angle X-ray scattering (SAXS) resource, the Center for Cancer Research (CCR) under the leadership of Drs. Jeffrey Read More...
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The OSTR offers cutting-edge technology platforms to the CCR scientific community through centralized facilities. The videos accessed through this page are designed to introduce the various scientific methodologies OSTR makes available through the cores on Read More...
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Bioinformatics
09/22/2021 - Registration is required. During this upcoming webinar, Dr. Yanjun Qi will demonstrate AttentiveChrome, an attention-based deep learning approach that uses a unified architecture to model and interpret interactions and dependencies among the chromatin factors Read More...
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Bioinformatics
11/18/2014 - Day 1 - AM (9:30-12:30) Introductory Lecture ( Peter FitzGerald, PhD - CCR, NCI ) Introduction Historical Perspective and Technical Variations Experimental methodology Comparison to ChIP-Chip Data Analysis Experimental Design Quality Control Peak Calling (Different methodologies) Major Read More...
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Bioinformatics
06/06/2024 - The CCR Genomics Core Facility is pleased to host a virtual technology workshop with EpiCypher on CUT&RUN library prep/sequencing Presentation overview: The location of histone post-translational modifications and chromatin-associated proteins Read More...
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Bioinformatics
05/07/2024 - Macros are ways to use code to substitute in a value, and using macros makes a code in SAS easier to read, easier to edit, less prone to errors, and often allows Read More...
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Bioinformatics
09/13/2023 - FORGEdb is a web-based tool that can rapidly integrate data for individual genetic variants, providing information on associated regulatory elements, transcription factor (TF) binding sites and target genes for over 37 million variants. Read More...
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Bioinformatics
Let's take another look at a simple scatter plot using the iris data. We can look at the relationship between petal length and petal width (i.e., variable association) for the various Iris species. Read More...
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Bioinformatics
02/23/2023 - Macros are ways to use code to substitute in a value, and using macros makes a code in SAS easier to read, easier to edit, less prone to errors, and often allows it to Read More...
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Bioinformatics
What do we need to make a plot: the data one or more geoms aesthetic mappings facets (i.e., subplots) use facet_grid(), facet_wrap() optional parameters that customize our plot (e.g., themes, axis Read More...
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Bioinformatics
When we use ls -l we are listing contents of a directory in the long view and are able to see additional details about a file or directory such as permissions, file size, and date Read More...
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Bioinformatics
06/06/2024 - The Brooks Lab developed a computational tool called FLAIR (Full-Length Alternative Isoform Analysis of RNA) to produce confident transcript isoforms from long-read RNA-seq data with the aim of alternative isoform detection and quantification. With Read More...
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Bioinformatics
Compare the output from these commands: ls ls -S ls -lh ls -h (when used with -l option, prints file sizes in a human readable format with the unit suffixes: Byte, Kilobyte, Megabyte, Gigabyte, Terabyte. Read More...
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Bioinformatics
The R scripts used for this class are in the folder b4b_scripts. Stay in /data/user/hcc1395_b4b and list the contents of b4b_scripts to learn what is available. These Read More...
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Bioinformatics
The last line, "An ill-considered change." added to mars.txt has not been staged for commit yet although git status will indicate that mars.txt has been modified. git status On branch main Read More...
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Bioinformatics
06/08/2021 - Do you want to know how to use Machine Learning (ML) for accelerating drug discovery? Join us on June 8, 1:00 pm – 2:00 pm ET, for the first in a series of workshops on how to use Read More...
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Bioinformatics
05/16/2016 - This 2-day course, which includes both lecture and hands-on components, will teach the basic concepts and practical aspects of ChIP-Seq Data Analysis. There will also be a talk on ENCODE and a comprehensive discussion Read More...
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Bioinformatics
In Lesson 2, I introduced the idea of command options (flags). Command options allow us to change the behavior of a command. Command options, which ultimately allow you to modify command parameters, are extremely important to Read More...
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Bioinformatics
A script allows users to string together analysis steps and keep them in one document. It can be reused with or without modification to analyze similar datasets. The script (SRR23341296_statistics.sh) below will use Read More...
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Bioinformatics
More useful Unix Flags and command options - making programs do what they do Use of wildcards Using tab complete for less typing Access your history with the "up" and "down" Read More...
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Bioinformatics
More useful Unix Flags and command options - making programs do what they do Use of wildcards Using tab complete for less typing Access your history with the "up" and "down" Read More...
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Bioinformatics
More useful Unix Flags and command options - making programs do what they do Use of wildcards Using tab complete for less typing Access your history with the "up" and "down" Read More...
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Bioinformatics
Lesson 4: Useful Unix For this lesson, you will need to login to the GOLD environment on DNAnexus. Lesson 3 Review Biowulf is the high performance computing cluster at NIH. When you apply for a Biowulf account Read More...
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Bioinformatics
Scatter plots and plot customization Objectives Learn to customize your ggplot with labels, axes, text annotations, and themes. Learn how to make and modify scatter plots to make fairly different overall plot representations. Load a Read More...