Frederick, MD
Collaborative
The Biopharmaceutical Development Program (BDP) provides resources for the development of investigational biological agents. The BDP supports feasibility through development and Phase I/II cGMP manufacturing plus regulatory documentation. The BDP was established in 1993. We Read More...
Frederick, MD
Core Facility
Repositories
Mouse models of human cancer have had a profound impact on our current understanding of the mechanisms of tumorigenesis and the pathways regulated by cancer-related genes. These models hold the promise of serving as critical Read More...
Bethesda, MD
Trans NIH Facility
NIH Intramural CryoEM Consortium (NICE) serves intramural investigators in all NIH IC’s. NICE provides access to state-of-the-art Titan Krios cryo-electron microscopes for atomic-resolution structure determination of protein, macromolecular complexes, membrane receptors, cellular organelles, and Read More...
Frederick, Maryland
Core Facility
Repositories
The Biological Products Core provides the AIDS research community with high-quality purified preparations of various strains of Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV), economically prepared by leveraging the economy of scale. Materials Read More...
Frederick, Maryland
Core Facility
CLIA-Certified Technologies Offered: Fragment Analysis for Micro-satellite Instability Detection, Pharmacoscan Array for Pharmacogenomics, Mutation Detection for PCR and Sanger Sequencing, DNA extraction from whole blood, saliva, FFPE tissues, buccal swabs, nails, hair, PBMCs, buffy coats, Read More...
Web Page
[tabby title="Home"] About NICE-NIH Intramural CryoEM Consortium NIH Intramural CryoEM Consortium (NICE) serves intramural investigators in all NIH IC’s. NICE provides access to state-of-the-art Titan Krios cryo-electron microscopes for atomic-resolution structure determination of Read More...
Web Page
Bioinformatics
07/27/2023 - This new webinar will be covering and discussing the host responses to vaccines with invited speakers Dr. Oliver He and Dr. Guanming Wu. During the hour long webinar, Vaccine Induced Gene Expression Analysis Tool ( Read More...
Web Page
Bioinformatics
10/20/2021 - Presenter: Trevor Bedford, Ph.D. Associate Professor Vaccine and Infectious Disease Division Human Biology Division Herbold Computational Biology Program Fred Hutchinson Cancer Research Center Genomic epidemiology has enabled critical insights during the COVID-19 pandemic. Read More...
Web Page
Bioinformatics
12/10/2019 - Please bring a laptop. If you need to borrow a laptop please contact ncibtep@nih.gov No software installation is needed as this program will run on a web browser. iCn3D provides a Read More...
Web Page
Bioinformatics
06/04/2021 - Speaker: Rangan Sreenivas Sukumar Distinguished Technologist Hewlett Packard Enterprise (HPE) Abstract: In March of 2020, the “Force for Good” pledge of intellectual property to fight COVID-19 brought into action HPE products, resources and expertise to Read More...
Web Page
Bioinformatics
Filtering joins result in filtered x data based on matching or non-matching with y . These joins do not add columns from y to x . semi_join() return all rows from x where there are matching Read More...
Web Page
Bioinformatics
Fisher Exact Test DAVID performs over representation analysis (ORA) at its core, which aims to find enriched molecular functions, pathways, or other annotations represented by the input gene list. In other words, many genes in Read More...
Web Page
Bioinformatics
Fisher Exact Test DAVID performs over representation analysis (ORA) at its core, which aims to find enriched molecular functions, pathways, or other annotations represented by the input gene list. In other words, many genes in Read More...
Web Page
Bioinformatics
04/02/2021 - Speaker: Tonia Korves, Ph.D. Lead Data Scientist Data and Human-Centered Solutions Innovation Center MITRE Corporation Abstract As COVID-19 research rapidly escalated last year, we quickly built a platform to help biomedical experts track Read More...
Web Page
Bioinformatics
Filtering joins result in filtered x data based on matching or non-matching with y. These joins do not add columns from y to x. semi_join() return all rows from x where there are matching Read More...
Web Page
Bioinformatics
Database for Annotation, Visualization and Integrated Discovery (DAVID) - an overview Before getting started, remember to be signed on to the DNAnexus GOLD environment. Lesson 17 review In the previous class, we got an overview of Read More...
Web Page
Bioinformatics
Here we are interested in functions that allow us to summarize our data. These include. group_by() - group a data frame by a categorical variable so that a given operation can be performed per Read More...
Web Page
Bioinformatics
For this portion of the lesson, let's change back into our data directory. Again, username is the username you used to sign into Biowulf, this could be your NIH username if you have Biowulf Read More...
Web Page
Bioinformatics
Fisher Exact Test DAVID performs over representation analysis (ORA) at its core, which aims to find enriched molecular functions, pathways, or other annotations represented by the input gene list. With DAVID, we are essentially looking Read More...
Web Page
Bioinformatics
The resulting object eh is a gseaResult object. This object contains the results (eh@result) and other information that went into the analysis, for example, @organism type, @setType, the @geneSets used, the genes in our @ Read More...
Web Page
Bioinformatics
Change into hcc1395_deg from hcc1395_b4b. cd hcc1395_deg List the contents. Use the -1 option to view directory contents 1 item per line. ls -1 The files generated from deg.R are: hcc1395_ Read More...
Web Page
Bioinformatics
dplyr : joining, tranforming, and summarizing data frames Objectives Today we will continue to wrangle data using the tidyverse package, dplyr . We will learn: how to join data frames using dplyr how to transform and create Read More...
Web Page
Bioinformatics
Database for Annotation, Visualization and Integrated Discovery (DAVID) - an overview Lesson 17 review In the previous class, we got an overview of functional and pathway analysis, which help to put RNA sequencing results into biological Read More...
Web Page
Bioinformatics
For tabular data in the form of csv files, which could contain multiple columns, the columns do not print to the terminal nicely aligned. The column command can fix this. The options and arguments in Read More...
Web Page
Bioinformatics
Required arguments: geneList - the ordered ranked gene list. TERM2GENE - a data frame including the terms and genes (the custom gene sets, which in this case were from MSigDB). Optional arguments: minGSSize - Read More...