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Search Results for: negative staining

Total Results Found: 72

Total Results Found: 72

BTEP course: Question 8

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Bioinformatics

Add a column to hcc1395_deg_chr22_1 that contains the negative log10 of the PAdj value. {{Sdet}}{{Ssum}}Solution{{Esum}} import numpy hcc1395_deg_chr22_1["-log10PAdj"]=numpy.negative(numpy.log10(hcc1395_deg_ Read More...

BTEP Lessons: Changing axes scales

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Bioinformatics

To change the y axis scale, we will need a specific function. These functions generally start with scale_y.... In our case we want to reverse our axis so that increasingly negative is going in Read More...

NIH Intramural CryoEM Consortium (NICE)
Bethesda, MD

Trans NIH Facility

NIH Intramural CryoEM Consortium (NICE) serves intramural investigators in all NIH IC’s. NICE provides access to state-of-the-art Titan Krios cryo-electron microscopes for atomic-resolution structure determination of protein, macromolecular complexes, membrane receptors, cellular organelles, and Read More...

BTEP Coding Club: Method outputs

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Bioinformatics

Enrichment Score and normalized enrichment score. Enrichment Score - represents the degree to which a set is over-represented at the top or bottom of the ranked list. normalized enrichment score (NES) - allows comparability across Read More...

NICE-NIH Intramural CryoEM Consortium

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[tabby title="Home"] About NICE-NIH Intramural CryoEM Consortium  NIH Intramural CryoEM Consortium (NICE) serves intramural investigators in all NIH IC’s. NICE provides access to state-of-the-art Titan Krios cryo-electron microscopes for atomic-resolution structure determination of Read More...

CHTN Mid-Atlantic Division (University of Virginia)
Charlottesville, VA

Repositories

Trans NIH Facility

The Mid-Atlantic CHTN is one of six participating divisions of the Cooperative Human Tissue Network (CHTN) and is based in the Pathology Department at the University of Virginia. While primarily a resource for cancer researchers, Read More...

Electron Microscopy

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Electron Microscopy Laboratory (EML) The EML offers investigators access to unique expertise and EM technologies that allow our partners to explore new avenues of research to enhance the knowledge of biological systems. To assist our Read More...

NCI Clinical Support Laboratory: Flow Cytometry Section
Frederick, MD

Core Facility

Clinical Support Laboratory – Flow Cytometry Section is a laboratory specializing in providing immunophenotyping support of NCI intramural clinical trials, though assessments may also be performed using cells from Non-human primates and other species. The CSL Read More...

Publications

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Confocal

2024 Coutinho, L. L., Femino, E. L., Gonzalez, A. L., Moffat, R. L., Heinz, W. F., Cheng, R. Y. S., Lockett, S. J., Rangel, M. C., Ridnour, L. A. & Wink, D. A. NOS2 and Read More...

Bioinformatics for Beginners 2022: Differential Expression

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Bioinformatics

Differential Expression Differential expression involves the comparison of normalized expression counts of different samples and the application of statistical measures to identify quantitative changes in gene expression between the different samples. Normalization and Statistical Significance Read More...

Data Visualization with R: Going beyond Excel

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Bioinformatics

Excel is a great program for visualizing and manipulating small data sets. However, it isn't great for working with "big data", and resulting plots are generally not publishable. Learning R and associated Read More...

Galaxy for Immunological and Infectious Disease Research

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Bioinformatics

09/04/2020 - Speakers: Dave Clements, Galaxy Community Manager, Johns Hopkins University, Steven Weaver, Senior Programmer Analyst, Temple University Galaxy is an open web-based platform for data integration and analysis in the life sciences. Galaxy makes sophisticated Read More...

BTEP Lessons: Example Data

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Bioinformatics

The example data we will use for plotting are from a bulk RNA-Seq experiment described by Himes et al. (2014) and available in the Bioconductor package airway. In this experiment, the authors were comparing transcriptomic differences Read More...

BTEP Lessons: Example data

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Bioinformatics

Here we will use bulk RNA-Seq data available in the R package airway, which is from an experiment published by Himes et al. (2014). These data, which are available in R as a RangedSummarizedExperiment object, are Read More...

BTEP Lessons: Example Data

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Bioinformatics

These example data are from a bulk RNA-Seq experiment described by Himes et al. (2014) and available in the Bioconductor package airway. ::: {.cell} #data import from excel exdata<-readxl::read_xlsx("./data/RNASeq_ Read More...

BTEP Coding Club: The Dataset

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Bioinformatics

For today's lesson, we will use data from the Bioconductor package airway. The airway data is from Himes et al. (2014). These data, which are contained within a RangedSummarizedExperiment, object are from a bulk RNAseq Read More...

CLIA Molecular Diagnostics Laboratory (CMDL)

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The CLIA Molecular Diagnostics Laboratory (CMDL) provides an array of services for groups at the NIH Clinical Center, Fort Detrick, and Hood College, among others. They support cancer- and disease-related research by making Read More...

NCI Molecular Cytogenetics Core Facility
Frederick, MD

Core Facility

Molecular Cytogenetics Core Facility facilitates the assessment of structural and numerical genomic changes in pre-cancer and cancer research models. This core provides comprehensive support for the cytogenetic analysis of cells from human and research animal Read More...

Biological Products Core (AIDS and Cancer Virus Program)
Frederick, Maryland

Core Facility

Repositories

The Biological Products Core provides the AIDS research community with high-quality purified preparations of various strains of Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV), economically prepared by leveraging the economy of scale. Materials Read More...

CLIA Molecular Diagnostics Laboratory
Frederick, Maryland

Core Facility

CLIA-Certified Technologies Offered: Fragment Analysis for Micro-satellite Instability Detection, Pharmacoscan Array for Pharmacogenomics, Mutation Detection for PCR and Sanger Sequencing, DNA extraction from whole blood, saliva, FFPE tissues, buccal swabs, nails, hair, PBMCs, buffy coats, Read More...

Clinical Support Laboratory
Frederick, MD

Core Facility

The Clinical Support Laboratory offers processing, tracking, and testing of a broad range of clinical samples. Support can begin at the early stages of clinical trial development to aid in developing a comprehensive strategy for Read More...

CCR Spatial Imaging Technology Resource (SpITR)
Bethesda, MD

Collaborative

The Spatial Imaging Technology Resource (formerly the Nanoscale Protein Analysis Section of the Collaborative Protein Technology Resource or CPTR) provides expertise and service in state-of-the-art protein analysis technologies to advance CCR research in basic discovery Read More...

Protein Characterization Laboratory

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Protein Characterization Laboratory (PCL) offers various technologies to CCR investigators to characterize proteins and metabolites. The laboratory develops and applies state-of-the-art analytical technologies, primarily mass spectrometry, liquid chromatography, and Surface Plasmon Resonance (SPR), to advance Read More...

CCR Protein Characterization Laboratory (PCL)
Frederick, MD

Core Facility

Protein Characterization Laboratory (PCL) offers various technologies to CCR investigators to characterize proteins and metabolites. The laboratory develops and applies state-of-the-art analytical technologies, primarily mass spectrometry, liquid chromatography, and Surface Plasmon Resonance (SPR), to advance Read More...

Past Seminars

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Confocal

2024 Date: Tuesday, October 15, 2024 Time and Location: 11 am EST, ZOOM (INVITATION BY LMIG LIST SERVER) Speaker: Dr. Diego Presman (U Buenos Aires) Title: “Insights on Glucocorticoid Receptor Activity Through Live Cell Imaging” Summary: Eucaryotic transcription factors ( Read More...

BTEP Coding Club: Tracking changes

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Bioinformatics

To start learning how to track changes using Git, a text file called mars will be created in the directory /Users/tillodc/teaching/planets. This file will contain notes about the planet mars. Note that Read More...

BTEP Coding Club: Results

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Bioinformatics

The resulting object eh is a gseaResult object. This object contains the results (eh@result) and other information that went into the analysis, for example, @organism type, @setType, the @geneSets used, the genes in our @ Read More...