Frederick, MD
Collaborative
The Center for Advanced Preclinical Research (CAPR) specializes in evaluating the efficacy of preclinical compounds, existing drugs, or biologics (therapeutics) in genetically engineered mouse (GEM) models, GEM-derived allograft (GDA) models, or patient-derived mouse xenografts (PDX). Read More...
Frederick, MD
Collaborative
The BRB Preclinical Repository is a central repository that supplies reagents to the broad research community. This NCI-sponsored repository is managed by NCI's Biological Resources Branch (BRB). The BRB Preclinical Repository stores cytokines, monoclonal antibodies, Read More...
Bethesda, MD
Trans NIH Facility
The Mouse Imaging Facility (MIF) is a shared, trans-NIH intramural resource for animal imaging studies. MIF provides access to state-of-the-art radiological imaging methods optimized for mice, rats, other animals and tissue samples. MIF provides intellectual, Read More...
Frederick, MD
Core Facility
The Laboratory Animal Sciences Program (LASP) of the Frederick National Laboratory operates a Gnotobiotics Facility (GF) to support research focused on the role of microbiota in cancer inflammation, pathogenesis, and treatment response. The GF can Read More...
Frederick, MD
Collaborative
The Chemical Synthesis Group is a component of the Chemical Biology Laboratory. This facility provides synthetic chemistry resources and expertise to the NCI Intramural community.The facility’s capabilities include:Providing expertise, consultation, and experience Read More...
Frederick, MD
Core Facility
NCI LASP Animal Research Technology Support (ARTS) provides customized technical support for basic and translational animal-based research to the scientific community. We offer a wide array of services ranging from expert colony management to the Read More...
Bethesda, MD
Core Facility
The PPS encompasses all scientific analyses related to pharmacology, once the specimen has been collected and stored. There is a multi-step process to evaluate how the drug is being handled by the body after administration. Read More...
Frederick, MD
Collaborative
NCI established the Nanotechnology Characterization Laboratory (NCL) to support the extramural research community to accelerate the progress of nanomedicine by providing preclinical characterization and safety testing of nanoparticles. It is a collaborative effort between NCI, Read More...
Bethesda, MD
Core Facility
Collaborative
Established Technologies: The Miner Suite of Bioinformatic Applications, These applications are freely available for public use. Our characterization and analysis of the NCI-60 cancer cell lines, the DNA, RNA, protein, epigenetic and pharmacological levels is Read More...
Frederick, MD
Collaborative
The Molecular Targets Program (MTP) is an organizational entity within the Center for Cancer Research (CCR) at NCI. The MTP provides the focus and infrastructure to enable CCR tenured and tenure-track Principal Investigators to initiate Read More...
Bethesda, MD
Core Facility
The Blood Processing Core monitors viral load in patients with HIV and performs sequential studies using samples obtained from patients with cancer, AIDS, chronic granulomatous disease, or other diseases associated with immunologic dysfunction. The core Read More...
Bethesda, Maryland
Collaborative
Trans NIH Facility
The Molecular Pathology Unit is intended to spearhead opportunities for bridging basic and clinical research efforts by more precisely optimizing the development, characterization and utilization of models of human disease. The initiative approach includes both Read More...
Bethesda, MD
Collaborative
The National Cancer Institute (NCI) is developing a national repository of Patient-Derived Models (PDMs) comprised of patient-derived xenografts (PDXs), patient-derived organoids (PDOrg) and in vitro patient-derived tumor cell cultures (PDCs) and cancer associated fibroblasts (CAFs). Read More...