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Search Results for: force spectroscopy

Total Results Found: 58

Total Results Found: 58

NIBIB Biomedical Engineering and Physical Science (BEPS)
Bethesda, MD

Trans NIH Facility

The Biomedical Engineering and Physical Science (BEPS) shared resource supports NIH’s intramural basic and clinical scientists on applications of engineering, physics, imaging, measurement, and analysis. BEPS is centrally located on the main NIH campus Read More...

R Introductory Series: Coerce to a matrix

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Bioinformatics

fun_mat column_to_rownames("sampleid") |> as.matrix(rownames.force=TRUE) fun_mat A B C D A1 0 352 400 278 B1 214 256 381 0 C1 0 0 250 169 Now, we can apply functions that require data matrices.

R Introductory Series: Coerce to a matrix

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Bioinformatics

::: {.cell} fun_mat column_to_rownames ( "sampleid" ) |> as.matrix ( rownames.force = TRUE ) fun_mat ::: {.cell-output .cell-output-stdout} A B C D A1 0 352 400 278 B1 214 256 381 0 C1 0 0 250 169 ::: ::: Now, we can apply functions that require data matrices.

Data Wrangling with R: Loading Tidyverse

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Bioinformatics

library(tidyverse) ## ── Attaching core tidyverse packages ──────────────────────── tidyverse 2.0.0 ── ## ✔ dplyr 1.1.3 ✔ readr 2.1.4 ## ✔ forcats 1.0.0 ✔ stringr 1.5.0 ## ✔ ggplot2 3.4.4 ✔ tibble 3.2.1 ## ✔ lubridate 1.9.3 ✔ tidyr 1.3.0 ## ✔ purrr 1.0.2 ## ── Conflicts ────────────────────────────────────────── tidyverse_conflicts() ── ## ✖ dplyr::filter() masks stats::filter() ## ✖ dplyr::lag() masks stats::lag() ## ℹ Use the conflicted package () to force Read More...

Center for Structural Biology: Biophysics Resource
Frederick, MD

Core Facility

The Biophysics Resource (BR) was established in January 2001. Our mission is to provide CCR investigators with access to both the latest instrumentation and expertise in characterizing the biophysical aspects of systems under structural investigation. The Read More...

CCR Electron Microscopy Laboratory (EML)
Frederick, MD

Core Facility

The EML offers investigators access to unique expertise and EM technologies that allow CCR Investigators to explore new avenues of research in order to enhance the knowledge of biological systems. To assist our customers, we Read More...

CCR Optical Microscopy and Analysis Lab (OMAL)
Frederick, MD

Core Facility

OMAL focuses its research and development activities to quantitatively understand the molecular basis of three-dimensional (3D) cell organization, motility, invasion, and differentiation using fixed samples and live, 3D tissue culture models (i.e., translational models). Read More...

Instrumentation

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Confocal

ZEISS Elyra 7 with Lattice SIM² Type: Wide-field structured illumination microscope Capabilities: Super resolution 2D and 3D imaging of live or fixed cells Apotome SIM: 170 nm lateral, 450 nm axial Apotome SIM2: 140 nm lateral, 300 nm axial Lattice Read More...

Past Seminars

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Confocal

2024 Date: Tuesday, October 15, 2024 Time and Location: 11 am EST, ZOOM (INVITATION BY LMIG LIST SERVER) Speaker: Dr. Diego Presman (U Buenos Aires) Title: “Insights on Glucocorticoid Receptor Activity Through Live Cell Imaging” Summary: Eucaryotic transcription factors ( Read More...

R Introductory Series: Loading the libraries

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Bioinformatics

To begin plotting, let's load our tidyverse library. #load libraries library(tidyverse) # Tidyverse automatically loads ggplot2 ## ── Attaching core tidyverse packages ──────────────────────── tidyverse 2.0.0 ── ## ✔ dplyr 1.1.3 ✔ readr 2.1.4 ## ✔ forcats 1.0.0 ✔ stringr 1.5.0 ## ✔ ggplot2 3.4.4 ✔ tibble 3.2.1 ## ✔ lubridate 1.9.3 ✔ tidyr 1.3.0 ## ✔ purrr 1.0.2 ## ── Conflicts ────────────────────────────────────────── tidyverse_conflicts() ── ## ✖ dplyr:: Read More...

Data Wrangling with R: Loading dplyr

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Bioinformatics

We do not need to load the dplyr package separately, as it is a core tidyverse package. If you need to install and load only dplyr , use install.packages("dplyr") and library(dplyr) . Read More...

Data Wrangling with R: Loading dplyr

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Bioinformatics

In this lesson, we are continuing with the package dplyr . We do not need to load the dplyr package separately, as it is a core tidyverse package. Again, if you need to install and load Read More...

Introductory R for Novices: Load the libraries

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Bioinformatics

This lesson will use some functions from the tidyverse. library(tidyverse) ── Attaching core tidyverse packages ──────────────────────── tidyverse 2.0.0 ── ✔ dplyr 1.1.4 ✔ readr 2.1.5 ✔ forcats 1.0.0 ✔ stringr 1.5.1 ✔ ggplot2 3.5.2 ✔ tibble 3.2.1 ✔ lubridate 1.9.4 ✔ tidyr 1.3.1 ✔ purrr 1.0.4 ── Conflicts ────────────────────────────────────────── tidyverse_conflicts() ── ✖ dplyr::filter() masks stats::filter() ✖ dplyr::lag() Read More...

Introductory R for Novices: Load the tidyverse

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Bioinformatics

We will use core packages from the tidyverse for our data wrangling needs. Data reshaping primarily involves the tidyverse package, tidyr, but we will use additional packages as well, such as tibble. Packages must be Read More...

Antibody Characterization Laboratory (ACL)
Frederick, MD

Collaborative

The Antibody Characterization Laboratory (ACL) is the laboratory responsible for the development of well-characterized monoclonal antibody reagents. The NCI’s Office of Cancer Clinical Proteomics Research funds ACL as a resource to the entire cancer Read More...

Electron Microscopy

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Electron Microscopy Laboratory (EML) The EML offers investigators access to unique expertise and EM technologies that allow our partners to explore new avenues of research to enhance the knowledge of biological systems. To assist our Read More...

NIH MRI Research Facility (NMRF)
Bethesda, MD

Trans NIH Facility

The NIH MRI Research Facility (NMRF) is a shared, intramural resource for human imaging studies. The NMRF is supported by all Institutes at NIH and reports to the Shared Resources Subcommittee (SRS) of the Scientific Read More...

July 2023 Newsletter

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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Cores on CREx NIBIB BEPS Micro Analytical Immunochemistry Unit The Micro Analytical Immunochemistry Unit employs a variety Read More...

R Introductory Series: Introducing ggplot2

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Bioinformatics

ggplot2 is an R graphics package from the tidyverse collection. It allows the user to create informative plots quickly by using a 'grammar of graphics' implementation, which is described as "a coherent system for Read More...

R Introductory Series: Load the data

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Bioinformatics

To explore tidyverse functionality, let's read in some data and take a look. #let's use our differential expression results dexp "ENSG00000000003", "ENSG00000000419", "ENSG00000000457", "E… $ albut untrt, Read More...

Data Wrangling with R: Challenge data load

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Bioinformatics

Load in a tab delimited file (file_path= "./data/WebexSession_report.txt") using read_delim() . You will need to troubleshoot the error message and modify the function arguments as needed. {{Sdet}} Solution } library ( Read More...

Cancer stem cell model and evolutionary dynamics

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Bioinformatics

04/12/2021 - Tumor heterogeneity and plasticity provide a driving force for tumor progression and metastasis as well as treatment response. Tumor heterogeneity can be explained by the same mechanisms that govern the developmental programs of an Read More...

BTEP Coding Club: Ignoring things (optional)

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Bioinformatics

Sometimes you don't want git to track certain files (e.g. backup files created by your text editor, large data files, intermediate analysis files). This can be achieved using a special configuration file .gitignore Read More...

NCI LASP Small Animal Imaging Program (SAIP)
Frederick, MD

Core Facility

The function of the SAIP is to collaborate with NCI investigators in the development of mouse models, new molecular imaging probes for early detection and therapy, monitor tumors in vivo, and perform drug efficacy studies Read More...

Fluorescence – PTI/Horiba QuantaMaster

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Back Services: Biophysics Facility offers fluorometers as open-access instruments.  First-time users must complete a short training session before gaining access to the instrument reservation calendar. Location: Building 50, room 3226 Description: Some substances reemit light after Read More...

Biophysics Core Technologies

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Home About the Biophysics Core Biophysics Core Services [tabby title="Instrumentation"] NHLBI Biophysics Core The Biophysics Core Facility: Overview Core Facilities provide scientific resources, cutting-edge technologies and novel approaches to support DIR scientists. Availability of Read More...

Data Wrangling with R: Help Session Lesson 5

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Bioinformatics

All solutions should use the pipe. Import the file "./data/filtlowabund_scaledcounts_airways.txt" and save to an object named sc . Create a subset data frame from sc that only includes the columns Read More...

Introductory R for Novices: Select and Filter

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Bioinformatics

All solutions use the pipe. Solutions have multiple possibilities. Q1. Import the file "./data/filtlowabund_scaledcounts_airways.txt" and save to an object named sc. Create a data frame from sc that only Read More...