Search Results for: cellular therapy

11/06/2024 - Join by meeting number:  Meeting number (access code): 2305 301 5709  Meeting password: RTdpZCg*255  

2024 Senatorov IS, Bowman J, Jansson KJ, Alilin AN, Capaldo BJ, Lake R, Riba M, Abbey YC, Mcknight C, Zhang X, Raj S, Beshiri ML, Shinn P, Ngyuyen H, Thomas CJ, Corey E, Kelly K. Castrate Read More...

Go under the Gene Ontology section in the Annotation Summary Results and expand on it. Click the chart view for GOTERM_BP_DIRECT to look at some biological processes that the upregulated genes in the Read More...

03/15/2021 - Abstract: Cancer represents an evolutionary process through which growing malignant populations genetically diversify, leading to tumour progression, relapse and resistance to therapy. In addition to genetic diversity, the cell-to-cell variation that fuels evolutionary selection Read More...

06/13/2024 - The schedule for this week consists of one presentation: Lorenz Adlung, UMC Hamburg-Eppendorf, will discuss: scMod: Marrying machine learning and deterministic modelling of longitudinal single-cell data Single-cell-based methods such as flow cytometry or single-cell Read More...

04/23/2024 - Join Dr. Kai Tan of the Children’s Hospital of Philadelphia as he discusses his cutting-edge technology, CytoCommunity, for the supervised and unsupervised discovery of tissue cellular neighborhoods. CytoCommunity offers a powerful Read More...

06/29/2022 - During this webinar, Computational Biologist Dr. Eytan Ruppin will present on “SELECT,” a computational approach that aims to identify clinically relevant synthetic lethal interactions, thereby harnessing them to predict patient response to cancer therapy Read More...

11/16/2020 - Register Cancer heterogeneity is one of the major challenges that hampers the ability to cure the disease. Tumors differ in their genetic profiles and the cellular interactions in the microenvironment, and each tumor may Read More...

05/20/2025 - In this talk, Dr. Hwang will discuss three examples of applying single-cell and spatial oncology approaches to the study of pancreatic cancer. First, he will explain how they utilized single-nucleus RNA-sequencing to uncover an Read More...

05/14/2025 - Please note: Registration is required to get the Meeting Link for this event. Please pre-register. The Human Tumor Atlas Network (HTAN) is a National Cancer Institute (NCI)-funded initiative to construct 3-dimensional atlases of Read More...

04/15/2025 - The Demystifying Medicine Series, jointly sponsored by FAES and NIH, includes presentations on pathology, diagnosis, and therapy in the context of major disease problems and current research. Primarily directed toward PhD students, clinicians and Read More...

04/02/2025 - Please note: Registration is required to get the Meeting Link for this event. Please pre-register. The Human Tumor Atlas Network (HTAN) is a National Cancer Institute (NCI)-funded initiative to construct 3-dimensional atlases of Read More...

01/14/2025 - Join leaders from  NCI’s Human Tumor Atlas Network  (HTAN) to hear about the program’s collaborative efforts to develop comprehensive atlases incorporating cellular, molecular, and histological dimensions across various cancer types and stages.  Read More...

10/16/2024 - Dear Colleagues,   Thanks to advances in single-cell genomics, researchers can construct large-scale organ atlases, giving you more accurate ways to study genetic mutations and alterations related to drug responses and disease. These Read More...

08/29/2024 - Dr. Mardis is an internationally recognized expert in cancer genomics, with ongoing interests in the integrated characterization of cancer genomes, defining DNA-based somatic and germline interactions and RNA-based pathways, and immune microenvironments that lead Read More...

There are data sets available in R to practice with or showcase different packages. For today's lesson and the remainder of this course, we will use data from the Bioconductor package airway to showcase Read More...

02/14/2024 - Explore the intricate world of pathway analysis with Reactome. Reactome is an open-source, manually-curated and peer-reviewed biological pathway knowledgebase, free and open to the public. We will provide you an overview of the contents Read More...

01/24/2024 - Dear colleagues,   Please join us on Wed., Jan. 24 when Dr. Avi Ma’ayan from the Icahn School of Medicine at Mount Sinai will demonstrate how to use these tools to access hundreds of thousands Read More...

We can use the airway package to see how this container works, including how to access and subset the data. What is the airway package? There are data sets available in R to practice with Read More...

12/12/2023 - Dr. Anant Madabhushi and his team have been developing computerized knowledge alignment, representation, and fusion tools for integrating and correlating heterogeneous biological data spanning different spatial and temporal scales, modalities, and functionalities. These tools Read More...

In the previous class, we got an overview of functional and pathway analysis, which help to put RNA sequencing results into biological context by informing us of things like biomolecular pathway, biological function, cellular localization, Read More...

This tool was created and is maintained by the Laboratory of Human Retrovirology and Immunoinformatics at Frederick National Lab. DAVID is used for functional analysis. Given an input gene list, DAVID will inform us of Read More...

This tool was created and is maintained by the Laboratory of Human Retrovirology and Immunoinformatics at Frederick National Lab. DAVID is used for functional analysis. Given an input gene list, DAVID will inform us of Read More...

GO terms provide information about a gene product GO terms as a vocabulary are species agnostic, but there are species constraints ontology and annotations are updated regularly computer readable - suitable for bioinformatics GO integrates Read More...

06/22/2023 - The Bhattacharya Lab at the UCSF Parnassus Campus is focused on the functional role of monocyte-derived macrophages in the onset and persistence of fibrosis in the lung. We are addressing the following major questions, Read More...

05/23/2023 - In this webinar, University of Wisconsin-Madison’s Dr. Tiwari shares how she and her laboratory have created machine learning (ML) techniques to better understand the basic biology of tumors through non-invasive imaging, Read More...

02/17/2023 - Dr. Brendan Miller is a post-doctoral research fellow at Johns Hopkins University in the Department of Biomedical Engineering. On Friday Feb 17, 1:00-2:00 PM, he will be discussing some tools he has recently helped develop Read More...

There are data sets available in R to practice with or showcase different packages. For today's lesson and the remainder of this course, we will use data from the Bioconductor package airway to showcase Read More...

11/16/2022 - Join Drs. Jennifer E. Beane-Ebel and Vijaya B. Kolachalama of Boston University as they discuss their studies of pathological and molecular alterations associated with lesion severity and progression. Topics include deep learning methods for Read More...

11/14/2022 - During this webinar, the  Genomic Data Commons ’ (GDC’s) Drs. Zhenyu Zhang and Bill Wysocki will review the different types of harmonized data that the GDC makes available for the cancer research community. The Read More...

05/04/2022 - For our next CDSL webinar we will have a guest lecture by  Dr. Julio Saez-Rodriguez from the Institute for Computational Biomedicine, Heidelberg. B io: Julio Saez-Rodriguez is Professor of Medical Bioinformatics and Data Analysis Read More...

02/17/2022 - Our goal is to understand how cellular heterogeneity encodes the molecular structure, function, and regulation of complex biological systems. Primarily using single cell genomics, we analyze systems by profiling their most fundamental units individually & Read More...

02/16/2022 - For our next CDSL webinar we will have a guest lecture by Dr. Leng Han from the Center for Epigenetics and Disease Prevention at Texas A&M University. Abstract: Despite advancements in Read More...

10/26/2021 - Meeting Link: https://cbiit.webex.com/cbiit/j.php?MTID=m14c6833bc06f89408464fac5bb2e8ce9 Human cells generate remarkable regulatory and functional complexity from a finite set of genes. Production of Read More...

10/14/2021 - Please plan to attend the Physician-Scientist Early Investigator Program (PEIP) seminar by: Nicholas Rydzewski, M.D. University of Wisconsin Dr. Rydzewski is currently Chief Resident in the Radiation Oncology Residency Program at the University Read More...

The Biopharmaceutical Development Program (BDP) provides resources for the development of investigational biological agents. The BDP supports feasibility through development and Phase I/II cGMP manufacturing plus regulatory documentation.The BDP was established in 1993. We Read More...

NCI established the Nanotechnology Characterization Laboratory (NCL) to support the extramural research community to accelerate the progress of nanomedicine by providing preclinical characterization and safety testing of nanoparticles. It is a collaborative effort between NCI, Read More...

Employing spatial biology techniques enables acquisition of transcript and protein data from intact tissue sections, and in turn, spatial distribution information and cellular interaction patterns are revealed.

The Antibody Engineering Program (AEP) is part of the Center for Cancer Research (CCR) at the National Cancer Institute (NCI). The program focuses on generating therapeutic antibodies by phage display technology, including human antibodies and Read More...

The NCI High-Throughput Imaging Facility (HiTIF) works in a collaborative fashion with NCI/NIH Investigators by providing them with the necessary expertise, instrumentation, and software to develop and execute advanced High-Throughput Imaging (HTI) assays. These Read More...

Many established and emerging technologies are available to CCR scientists.  This technology-rich environment makes the CCR a unique place to conduct scientific research.  Through the OSTR, the CCR continues to find Read More...

.row { display: flex; justify-content: space-around; align-items: flex-start; margin: 20px; } .column { text-align: center; padding: 10px; width: 30%; } .column img { display: block; margin: 0 auto; width: 150px; height: 150px; } .column strong { display: block; margin-top: 10px; } Background: Intravital microscopy (IVM) Read More...

Radiology and Imaging Sciences provides imaging services for National Institutes of Health (NIH) Clinical Center patients participating in research protocols conducted by the various NIH institutes. Services include X-rays, fluoroscopy, ultrasound, magnetic resonance imaging (MRI) Read More...

Confocal Microscope Image of Fixed Mouse Embryonic Fibroblast (MEF) Cells Actin proteins (stained red) and Tubulin proteins (stained green) are involved in a number of cellular process such as cell motility, cell division and maintenance Read More...

2024 Coutinho, L. L., Femino, E. L., Gonzalez, A. L., Moffat, R. L., Heinz, W. F., Cheng, R. Y. S., Lockett, S. J., Rangel, M. C., Ridnour, L. A. & Wink, D. A. NOS2 and Read More...

01/19/2022 - For our next CDSL Webinar we will have a guest lecture by  Dr. Russell Rockne from Beckman Research Institute, City of Hope National Medical Center. Abstract: Temporal dynamics of gene expression inform cellular and Read More...

05/29/2025 - Prostate cancer exhibits significant intratumoral heterogeneity, driving a spectrum of phenotypes ranging from indolent disease to aggressive metastasis, challenging risk stratification and treatment. A key feature of this heterogeneity is clonal diversity, encompassing both Read More...

05/19/2025 - Immunotherapy has the potential to revolutionize the way we treat cancer, but a key challenge has been finding ways to tailor that therapy to the right patient at the right time. Attend this webinar, Read More...

04/10/2025 - TumorDecon is a computational tool at an early stage of contributing to the intersection of bioinformatics and oncology. The goal of TumorDecon is to estimate the percentages of various immune cells from gene expression Read More...

04/09/2025 - Please note: Registration is required to get the Meeting Link for this event. Please pre-register. The Human Tumor Atlas Network (HTAN) is a National Cancer Institute (NCI)-funded initiative to construct 3-dimensional atlases of Read More...

03/19/2025 - Please note: Registration is required to get the Meeting Link for this event. Please pre-register. The Human Tumor Atlas Network (HTAN) is a National Cancer Institute (NCI)-funded initiative to construct 3-dimensional atlases of Read More...

09/23/2024 - Come to the Fair!  In the morning session, several different groups will speak about their training and education programs. The afternoon session will be devoted to learning about research using AI across Read More...

07/11/2024 - Please join us for this special event featuring three speakers on the topic of Single-Cell Spatial Transcriptomics. George Zaki, Ph.D., Director, Applied Scientific Computing, BACS, The Frederick National Lab for Cancer Research, NCI/ Read More...

VlnPlot(adp, features = "percent.mt", group.by="orig.ident") + scale_fill_manual(values=cnames) + geom_hline(yintercept=10,color="red") Warning: Default search for "data" layer in " Read More...

There are several metrics that can be used to assess overall quality. The base workflow from Seurat suggests the following: nCount_RNA - the absolute number of RNA molecules (UMIs) per cell (i.e., count Read More...

04/19/2024 - Dear Colleagues,    This webinar will introduce TumorDecon, a computational tool that's at an early stage of contributing to the intersection of bioinformatics and oncology.   TumorDecon aims to Read More...

03/29/2024 - This event is sponsored by an organization outside of the NIH; it is listed here due to the nature of the presented topics and their appeal to the NCI community. Description: Recent developments in Read More...

03/20/2024 - Our series of talks continues with two 20-minute presentations.  There will be light refreshments (coffee and donuts) provided, so please consider attending in person! We encourage attendees to stay and chat with Read More...

In lesson 3, we learned how to read and save excel spreadsheet data to a R object using the tidyverse package readxl . Today we will use some example data from an excel spreadsheet to learn the Read More...

In tab delimited files, data columns are separated by tabs. To import tab-delimited files there are several options. There are base R functions such as read.delim() and read.table() as well as the readr Read More...

12/08/2023 - This presentation will discuss strategies and policies for effective sharing and reuse of large multidimensional datasets. Dr. Espinosa will discuss his experiences as a data generator, data analyst, collaborator, teacher, and mentor through the Read More...

10/03/2023 - Multiplexed antibody-based imaging enables the detailed characterization of molecular and cellular organization in tissues. Significant advances in the field now allow high-parameter data collection (60+ targets); however, considerable expertise and capital are needed to validate Read More...

Database for Annotation, Visualization and Integrated Discovery (DAVID) - practicing what we learned Learning objectives In this practice session, we will practice using DAVID. Practicing what we learned To help us apply what we learned Read More...

Let's submit a batch job. We are going to download data from the Sequence Read Archive (SRA) , a public repository of high throughput, short read sequencing data. We will discuss the SRA a bit Read More...

Excel is a great program for visualizing and manipulating small data sets. However, it isn't great for working with "big data", and resulting plots are generally not publishable. Learning R and associated Read More...

11/02/2022 - Join Emory University’s Dr. Anant Madabhushi as he discusses the   Center for Computational Imaging and Personalized Diagnostics ’ (CCIPD’s) development work on new radiomic and pathomic approaches for capturing intra-tumoral heterogeneity and modeling Read More...

10/26/2022 - In partnership with NCI’s Cancer Moonshot SM  Initiative, the Society for Immunotherapy of Cancer (SITC) and the  Big Data  and  Data Sharing  Committee are hosting the eighth of nine webinars that make up Read More...

10/19/2022 - Speaker: Ron Germain, M.D., Ph.D. NIH Distinguished Investigator NIAID, NIH Dr. Germain received his Sc.B. and Sc.M. from Brown University in 1970 and his M.D. and Ph.D. from Harvard Read More...

10/05/2022 - For our next CDSL webinar we will have presentations by two CDSL fellows:  Ekaterina Kazantseva  and Sanna Madan.  Ekaterina is a master’s student in Dr. Mikhail Kolmogorov's group and the title of Read More...

09/27/2022 - Course Objectives: This 12-week long course is for scientists wanting to learn basic bioinformatics skills. Material will be taught at a beginner to intermediate level. There are no pre-requisites. Learners will: Learn Unix skills Read More...

08/24/2022 - Precision oncology has made significant advances, mainly by targeting actionable mutations and fusion events involving cancer driver genes. Aiming to expand treatment opportunities, recent studies have begun to explore the utility of tumor transcriptome Read More...

06/16/2022 - Sarah Teichmann is co-founder and principal leader of the Human Cell Atlas (HCA) international consortium. The International Human Cell Atlas initiative aims to create comprehensive reference maps of all human cells to further understand Read More...

06/16/2022 - Sarah Teichmann, Ph.D., Fellow of the Academy of Medical Sciences (UK FMedSci), Fellow of the Royal Society (FRS), Wellcome Sanger Institute Sarah Teichmann is co-founder and principal leader of the Human Cell Atlas ( Read More...

05/25/2022 - Dr. Peng Jiang of NCI’s Center for Cancer Research will discuss  CytoSig , a software-based platform that is designed to provide both a  database  of target genes modulated by cytokines (i.e., proteins secreted Read More...

05/19/2022 - THIS EVENT HAS BEEN CANCELLED Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood and are subdivided into three major histomorphologic subtypes: alveolar (ARMS), embryonal (ERMS), or spindle/sclerosing (SSRMS).  Patients with Read More...

05/12/2022 - The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Office of the Scientific Director invites you to the Division of Intramural Research (DIR) Tenure-Track Investigator Virtual Symposia Series. Speakers: Timothy Read More...

03/10/2022 - Attendees will learn how to use Partek Flow to identify cell subtypes using both gene and protein expression in a peripheral blood mononuclear cell (PBMC) sample using Cellular Indexing of Transcriptomes and Epitopes by Read More...

02/17/2022 - Rahul Satija, D.Phil., Core Faculty Member, New York Genome Center, Associate Professor of Biology, Center for Genomics and Systems Biology, New York University (NYU), Associate Faculty, Institute for Systems Genetics, NYU Langone Medical Read More...

02/11/2022 - Dr. Jeremy Goecks will share how cancer researchers are using the machine learning capabilities of the Galaxy project, one of the largest and most widely used open-source platforms for biomedical  data science , to predict Read More...

01/25/2022 - Speaker: Anant Madabhushi, Ph.D. Donnell Institute Professor of Biomedical Engineering Director, Center for Computational Imaging and Personalized Diagnostics (CCIPD) Case Western Reserve University (CWRU),  Cleveland Anant Madabhushi, PhD, is a Research Scientist at Read More...

01/11/2022 - Please plan to attend the Earl Stadtman Investigator Program search seminar by: Augustin Luna, Ph.D. Harvard Medical School Dr. Luna's research focuses on the analysis of complex biological systems to understand and Read More...

11/19/2021 - High-resolution, whole-brain microscopy provides unprecedented new insights into the brain’s structural organization, molecular diversity and connectivity. The Brain Image Library (BIL) provides infrastructure that facilitates the sharing of this valuable data, enabling investigators Read More...

10/28/2021 - Single-cell RNA sequencing (scRNA-seq) is a relatively new and powerful method in genomics, which enables the interrogation of whole single cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a basic scRNA-seq workflow, Read More...

10/21/2021 - RNA sequencing (RNA-seq) is a widely used method in genomics, which enables the interrogation of whole cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a RNA-seq workflow on the NIDAP collaboration platform, Read More...

10/14/2021 - Single-cell RNA sequencing (scRNA-seq) is a relatively new and powerful method in genomics, which enables the interrogation of whole single cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a basic scRNA-seq workflow, Read More...

10/07/2021 - RNA sequencing (RNA-seq) is a widely used method in genomics, which enables the interrogation of whole cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a RNA-seq workflow on the NIDAP collaboration platform, Read More...

09/30/2021 - Single-cell RNA sequencing (scRNA-seq) is a relatively new and powerful method in genomics, which enables the interrogation of whole single cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a basic scRNA-seq workflow, Read More...

09/23/2021 - RNA sequencing (RNA-seq) is a widely used method in genomics, which enables the interrogation of whole cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a RNA-seq workflow on the NIDAP collaboration platform, Read More...

09/16/2021 - Single-cell RNA sequencing (scRNA-seq) is a relatively new and powerful method in genomics, which enables the interrogation of whole single cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a basic scRNA-seq workflow, Read More...

09/02/2021 - RNA sequencing (RNA-seq) is a widely used method in genomics, which enables the interrogation of whole cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a RNA-seq workflow on the NIDAP collaboration platform, Read More...

No summary available.

CCR VOLUME Electron Microscopy (CVEM) aims to develop new techniques in volume electron microscopy (vEM) and, in collaboration with CCR Investigators, apply these techniques to research cell biological questions well-suited for study by high-resolution 3D Read More...

The Clinical Flow Cytometry Laboratory provides extensive support for NCI clinical protocols by providing diagnostic testing for leukemia and lymphoma in patients either on NCI clinical protocols or undergoing testing to determine eligibility for NCI Read More...

The NIH Clinical Center Pharmacy Department provides pharmaceutical care to inpatients and outpatients on NIH intramural research protocols at the NIH Clinical Center. The Clinical Center facility encompasses 200 inpatient beds, 93 day-hospital stations, and 15 clinics. Clinical Read More...

The Genomics and Pharmacology Facility is part of the NCI's Center for Cancer Research (CCR), within the Developmental Therapeutics Branch. Its mission is to manage and assess molecular interaction data obtained through multiple platforms, increase Read More...

Protein/Protein Interaction Database Through a license agreement with Elsevier, the CCR community has access to the largest Y2H data set available in the world (CCR Database of Antibodies and Protein Interactions, C-DAPI). This Read More...

CREx News & Updates July 2021   Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGHLIGHTS Learn more about services from the NHLBI Read More...

The Pan-Microbial Serology Facility (PMSF) is part of the Center for Cancer Research (CCR) at the National Cancer Institute (NCI). The PMSF focuses on determining individualized pan-microbial immune profiles associated with human diseases including immunological Read More...

The Clinical Support Laboratory offers processing, tracking, and testing of a broad range of clinical samples. Support can begin at the early stages of clinical trial development to aid in developing a comprehensive strategy for Read More...

[embed]https://youtu.be/yTl1Q0D7aZ0[/embed] 10x Genomics' supports multiple cancer research areas from single nucleotide and structural variant detection to single cell whole transcriptome gene expression analysis of thousands of individual Read More...

Protein Characterization Laboratory (PCL) offers various technologies to CCR investigators to characterize proteins and metabolites. The laboratory develops and applies state-of-the-art analytical technologies, primarily mass spectrometry, liquid chromatography, and Surface Plasmon Resonance (SPR), to advance Read More...

The function of the SAIP is to collaborate with NCI investigators in the development of mouse models, new molecular imaging probes for early detection and therapy, monitor tumors in vivo, and perform drug efficacy studies Read More...

The Neurorehabilitation and Biomechanics Research Section (also referred to as the NAB LAB) is a multidisciplinary group of highly qualified scientists, clinical and technical staff, and trainees with diverse backgrounds including medical, physical therapy, neuroscience Read More...

The Clinical Image Processing Service (CIPS) offers timely and accurate advanced image processing of diagnostic radiology images for clinical care, research, and training. CIPS’ functions include clinical services and scientific researches. Established Technologies: CIPS can Read More...

NIH Intramural CryoEM Consortium (NICE) serves intramural investigators in all NIH IC’s. NICE provides access to state-of-the-art Titan Krios cryo-electron microscopes for atomic-resolution structure determination of protein, macromolecular complexes, membrane receptors, cellular organelles, and Read More...

The CCR Microscopy Core provides NCI investigators access to state-of-the-art imaging tools and techniques, including light sheet fluorescence, high-resolution confocal, multi-photon, and super-resolution microscopy. The mission of the CCR Microscopy Core Facility is to support Read More...

Protein Characterization Laboratory (PCL) offers various technologies to CCR investigators to characterize proteins and metabolites. The laboratory develops and applies state-of-the-art analytical technologies, primarily mass spectrometry, liquid chromatography, and Surface Plasmon Resonance (SPR), to advance Read More...

The Chemistry and Synthesis Center (CSC) of the National Heart, Lung, and Blood Institute (NHLBI) provides IRP scientists with targeted imaging probes and chemical tools that help accelerate cell-based assays, in vivo imaging studies, and Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx User Survey The CREx Team is carrying out a CREx User Survey. We would greatly appreciate Read More...

CREx News & Updates July 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Click below to learn how easy it is to navigate the CREx platform. These short videos will Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx User Survey The CREx Team is carrying out a CREx User Survey. If you haven’t Read More...

The NCI Genomic Data Commons (GDC) was established by the NCI Center for Cancer Genomics (CCG) to support the receipt, harmonization, distribution, and analysis of genomic and clinical data from cancer research programs. The GDC Read More...

The AgingResearchBiobank was officially launched in January 2019 with a mission to provide a state-of-the-art inventory system for the storage, maintenance, and distribution of de-identified biospecimens and associated phenotypic, clinical, and imaging data from numerous NIA-funded Read More...

As a multi-user facility, the different instruments provide a wide range of imaging modes for EIB scientists, from standard immunohistochemistry, through brightfield and wide-field epifluorescence imaging, to highly complex live cell confocal microscopy and super-resolution Read More...

The Spatial Imaging Technology Resource (formerly the Nanoscale Protein Analysis Section of the Collaborative Protein Technology Resource or CPTR) provides expertise and service in state-of-the-art protein analysis technologies to advance CCR research in basic discovery Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New NIH Resource Resources Advance your research with the NIH Mouse Imaging Facility (MIF) The NIH Mouse Imaging Read More...

[tabby title="Home"] About NICE-NIH Intramural CryoEM Consortium  NIH Intramural CryoEM Consortium (NICE) serves intramural investigators in all NIH IC’s. NICE provides access to state-of-the-art Titan Krios cryo-electron microscopes for atomic-resolution structure determination of Read More...

Listed below are the video recordings of past BTEP events (classes, seminars, workshops). Videos are hosted on various servers and may play slightly differently. Some videos may be downloaded for local viewing. Recorded Videos of Read More...

Register now for an upcoming seminar on January 22, 2025 , “Revealing Tumor-Promoting Signals in Breast Cancer Subtypes: A NIDAP Analysis of Single-Cell Data” . This one-hour talk will feature guest speaker and NIDAP developer, Josh Meyer, who will Read More...

Learning Objectives This tutorial was designed to demonstrate common secondary analysis steps in a scRNA-Seq workflow. We will start with a merged Seurat Object with multiple data layers representing multiple samples. Throughout this tutorial we Read More...

Learning Objectives Learn about data structures including factors, lists, data frames, and matrices. Load, explore, and access data in a tabular format (data frames) Learn to write out (export) data from the R environment Data Read More...

Introduction to ggplot2 Objectives Learn the ggplot2 syntax. Build a ggplot2 general template. By the end of the course, students should be able to create simple, pretty, and effective figures. Data Visualization in the tidyverse Read More...

Objectives To explore Bioconductor, a repository for R packages related to biological data analysis. To better understand S4 objects as they relate to the Bioconductor core infrastructure. To learn more about a popular Bioconductor S4 Read More...

Data import and reshape Objectives 1. Learn to import multiple data types 2. Data reshape with tidyr : pivot_longer() , pivot_wider() , separate() , and unite() Installing and loading packages So far we have only worked with objects that Read More...

Database for Annotation, Visualization and Integrated Discovery (DAVID) - an overview Before getting started, remember to be signed on to the DNAnexus GOLD environment. Lesson 17 review In the previous class, we got an overview of Read More...

Database for Annotation, Visualization and Integrated Discovery (DAVID) - an overview Lesson 17 review In the previous class, we got an overview of functional and pathway analysis, which help to put RNA sequencing results into biological Read More...

Lesson 5: Working on Biowulf Lesson 4 Review Flags and command options Wildcards ( * ) Tab complete Accessing user history with the "up" and "down" arrows cat , head , and tail Working with file content (input, Read More...

Gene ontology and pathway analysis Objectives Determine potential next steps following differential expression analysis. Tour geneontology.org and understand the three main ontologies. Learn about different methods and tools related to functional enrichment and pathway Read More...

Introduction to ggplot2 Objectives Learn how to import spreadsheet data. Learn the ggplot2 syntax. Build a ggplot2 general template. By the end of the course, students should be able to create simple, pretty, and effective Read More...

The identification of cell types in single cell genomics data (cell type annotation) can provide new insights into cellular identities, heterogeneity, and functional roles. Cell type annotation is challenging Read More...

Data frames Objectives To be able to load, explore, and access data in a tabular format. To this end, students should understand the following: 1. how to import and export data 2. how to create, summarize, and Read More...

06/22/2022 - Cancer origination and progression is a complex process that can be viewed as a somatic evolutionary progression with clonal cellular expansion(s) driven by accumulation of survival-/evasion-beneficial genomic mutations, alongside constantly changing selective Read More...