Frederick, MD
Core Facility
Protein and Metabolite Characterization Core (PMCC), formerly known as the Protein Characterization Lab (PCL), offers various technologies to CCR investigators to characterize proteins and metabolites. The core develops and applies state-of-the-art analytical technologies, primarily mass Read More...
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What is Xenium? Xenium is a high-resolution, imaging-based in situ spatial profiling technology from 10x Genomics that allows for simultaneous expression analysis of RNA targets (currently in range of 100’s) within the same tissue section. Read More...
Bethesda, MD
Collaborative
The Spatial Imaging Technology Resource (formerly the Nanoscale Protein Analysis Section of the Collaborative Protein Technology Resource or CPTR) provides expertise and service in state-of-the-art protein analysis technologies to advance CCR research in basic discovery Read More...
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Biomarker Discovery with Morphological Context: Changing how tissue specimens are analyzed < https://youtu.be/mVhfZq8ppbc What is Digital Spatial Profiling? GeoMx Digital Spatial Profiler is a novel platform developed by NanoString. Digital Spatial Read More...
Bethesda, MD
Trans NIH Facility
The Center for Inherited Disease Research (CIDR)'s mission is to support the genetics community by providing high-quality, cutting-edge genomics services and technologies in order to expand our understanding of disease and catalyze discoveries that Read More...
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CREx News & Updates September 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGLIGHTS Learn more about services from the CCR Read More...
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Mass Spectrometry Section of the Collaborative Protein Technology Resource (Bldg. 37) Core Capabilities: Identification of proteins in complexes, organelles, subcellular fractions, or fluids. Global relative protein quantitation. Quantitation by isotopic labeling of cells in culture (SILAC) Read More...
Federick, MD
Core Facility
The Mass Cytometry Core (MCC) provides access to cutting-edge platforms and expert technical support for high-dimensional single-cell analysis and spatial proteomic profiling. A central expertise of the core is Imaging Mass Cytometry (IMC), which allows Read More...
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Employing spatial biology techniques enables acquisition of transcript and protein data from intact tissue sections, and in turn, spatial distribution information and cellular interaction patterns are revealed.
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Extramural Common Fund Resources Metabolomics Workbench Developed by the NIH Metabolomics Common Fund's National Metabolomics Data Repository ( Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Intramural Core Resources NHGRI Flow Cytometry Core The Core performs high quality single cell analysis through the Read More...
Frederick, MD
Collaborative
The Molecular Targets Program (MTP) is an organizational entity within the Center for Cancer Research (CCR) at NCI. The MTP provides the focus and infrastructure to enable CCR tenured and tenure-track Principal Investigators to initiate Read More...
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Employing spatial biology techniques enables acquisition of transcript and protein data from intact tissue sections, and in turn, spatial distribution information and cellular interaction patterns are revealed.
Research Training Park, NC
Core Facility
Trans NIH Facility
The NIH Metabolomics Consortium (NIH-MC) is a shared research resource that performs metabolomics analysis (and related small molecule research) for investigators at all Institutes and Centers across the NIH Intramural Research Program. The NIH-MC is Read More...
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Supplemental Technology Award Review System (STARS) Overview STARS Request Form STARS System The Supplemental Technology Award Review System (STARS) is a web-based interface for submission and review of S&S supplement requests by CCR Read More...
Bethesda, MD
Core Facility
The CCR Genomics Core is located in Building 41 on the NIH Bethesda campus. The primary goal of the Core is to provide investigators from CCR/NCI and other NIH Institutes access to genomic technologies and Read More...
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Protein/Protein Interaction Database Through a license agreement with Elsevier, the CCR community has access to the largest Y2H data set available in the world (CCR Database of Antibodies and Protein Interactions, C-DAPI). This Read More...
Rockville, MD
Core Facility
The Chemistry and Synthesis Center (CSC) of the National Heart, Lung, and Blood Institute (NHLBI) provides IRP scientists with targeted imaging probes and chemical tools that help accelerate cell-based assays, in vivo imaging studies, and Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New Resources on CREx Trans-NIH Metabolomics Core (TNMC) The TNMC is a shared research resource that provides targeted Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Intramural CryoEM (NICE) Consortium NICE provides NCI, NIAID, NIEHS, NICHD, NIDCR, NEI, and NIA investigators with Read More...
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[embed]https://youtu.be/yTl1Q0D7aZ0[/embed] 10x Genomics' supports multiple cancer research areas from single nucleotide and structural variant detection to single cell whole transcriptome gene expression analysis of thousands of individual Read More...
Bethesda, MD
Trans NIH Facility
The NIH Center for Human Immunology, Inflammation, and Autoimmunity (CHI) is a trans-NIH resource whose mission is to provide a collaborative hub of advanced translational immunology for NIH clinical and pre-clinical studies. This uniquely structured Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New Resources on CREx NCI CLIA Molecular Diagnostics Laboratory (CMDL) The NCI CMDL is available to assist all Read More...
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Total end-to-end system for single-cell research [embed]https://youtu.be/vMzhSzg1rUw[/embed] The BD Rhapsody Single-Cell Analysis system empowers and streamlines your research with a complete system of tools, including reagents and analysis software, Read More...
Bethesda, MD
Core Facility
The NHLBI Transgenic Core’s main mission is to keep up with the latest advancements in genome engineering technologies and to provide state-of-the-art services to assist NIH scientists in generating genetically engineered animal models. In Read More...
Frederick, MD
Core Facility
NCI LASP Genome Modification Core (GMC) is a CCR-dedicated facility that provides advice, training, and reagents to NCI scientists seeking to utilize CRISPR and other nucleases to generate genome modifications in primary cells, cell lines, Read More...
Bethesda, MD
Collaborative
The Mass Spectrometry Unit of the Collaborative Protein Technology Resource uses mass spectrometry for the study of proteins. We perform collaborative experiments with CCR researchers in areas such as: interactomes, quantitative global proteome analyses, and Read More...
Frederick, MD
Core Facility
The function of the SAIP is to collaborate with NCI investigators in the development of mouse models, new molecular imaging probes for early detection and therapy, monitor tumors in vivo, and perform drug efficacy studies Read More...
Rockville, MD
Trans NIH Facility
The Functional Genomics Laboratory (formerly, the RNAi Screening Facility) of the National Center for Advancing Translational Sciences (NCATS) assist investigators with all stages of project planning and execution, beginning with assay development through genome-wide siRNA Read More...
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What is Visium FFPE v2 with CytAssist? Visium FFPE v2 is sequencing-based spatial profiling technology developed by 10x Genomics. This assay can take mouse or human tissue sections on normal glass slides as input and Read More...
Bethesda, MD
Collaborative
The CCR Collaborative Bioinformatics Resource (CCBR) is a centrally funded resource group which provides a mechanism for CCR researchers to obtain many different types of bioinformatics assistance to further their research goals. The group has Read More...
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CREx News & Updates July 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Click below to learn how easy it is to navigate the CREx platform. These short videos will Read More...
Frederick, MD
Core Facility
Repositories
Mouse models of human cancer have had a profound impact on our current understanding of the mechanisms of tumorigenesis and the pathways regulated by cancer-related genes. These models hold the promise of serving as critical Read More...
Bethesda, MD
Core Facility
The Genomics and Pharmacology Facility is part of the NCI's Center for Cancer Research (CCR), within the Developmental Therapeutics Branch. Its mission is to manage and assess molecular interaction data obtained through multiple platforms, increase Read More...
Bethesda, MD
Collaborative
Our operational objectives are to provide state-of-the-art OMICS technologies in support of the Genetics Branch (GB) investigators and collaborators. Research Services Wet Lab Single cell isolation from fresh, frozen, and FFPE tissue, DNA/RNA extractions Read More...
Frederick, MD
Collaborative
The Biopharmaceutical Development Program (BDP) provides resources for the development of investigational biological agents. The BDP supports feasibility through development and Phase I/II cGMP manufacturing plus regulatory documentation. The BDP was established in 1993. We Read More...
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Bioinformatics
09/12/2022 - We welcome members of the NIH to join us for a seminar event, covering multiplexed, direct digital gene expression profiling applications utilizing NanoString nCounter expression profiling technology as well as spatial biology discoveries generated Read More...
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Bioinformatics
03/11/2021 - Abstract: Targeted quantitative proteomics using multiple/parallel reaction monitoring (MRM, PRM) is already being applied by many researchers in biology, biochemistry, and clinical research laboratories. These methods allow rapid and precise quantitation of proteins Read More...
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Bioinformatics
06/16/2020 - The capability to unambiguously and comprehensively identify thousands of metabolites and other chemicals in clinical samples, including the microbiome, will revolutionize the search for environmental, dietary, and metabolic determinants of health and disease. By Read More...
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Bioinformatics
08/29/2024 - Dr. Mardis is an internationally recognized expert in cancer genomics, with ongoing interests in the integrated characterization of cancer genomes, defining DNA-based somatic and germline interactions and RNA-based pathways, and immune microenvironments that lead Read More...
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Bioinformatics
11/09/2022 - Speakers: Amanda Phipps, PhD, MPH Associate Professor and Associate Chair of Epidemiology Department of Epidemiology University of Washington School of Public Health Tabitha Harrison, MPH Research Scientist University of Washington School of Public Health Read More...
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Bioinformatics
03/04/2024 - The NCI Cancer Imaging Program presents a new monthly webinar series highlighting advancements in our imaging community. Please join us for our next lecture in the series Dr. McNally earned her Ph.D. in Read More...
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Bioinformatics
05/17/2021 - For our next meeting we will be having a guest lecture by Dr. Josh Waterfall from Institut Curie. Abstract: Non small cell lung cancers (NSCLC) are known to be recurrently infiltrated by multiple immune Read More...
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Bioinformatics
09/20/2022 - Dr. Mikhail Kolmogorov, Stadtman Investigator, Cancer Data Science Laboratory, NCI (guest of Pedro Batista) will present a lecture: Please join us for a hybrid LCB seminar/webinar via ZoomGov and in Conference Room 37/2041 Meeting Read More...
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Bioinformatics
07/27/2022 - Many recent studies highlighted the improved capability of long-read sequencing to detect structural variation in the human genome. For example, these technologies was also recently utilized to produce the first complete assembly of the Read More...
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Bioinformatics
04/15/2021 - Presenter: Ichiro Hiratani, Ph.D. Team Leader Laboratory for Developmental Epigenetics RIKEN Center for Biosystems Dynamics Research (RIKEN BDR), Japan JOIN WEBEX MEETING https://cbiit.webex.com/cbiit/j.php?MTID=m13d114a534 Read More...
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Bioinformatics
11/06/2024 - Join by meeting number: Meeting number (access code): 2305 301 5709 Meeting password: RTdpZCg*255
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Bioinformatics
01/25/2023 - These virtual monthly seminars showcase a novel technology being supported through NCI that could transform cancer research and clinical care. During the January seminar, Dr. Jenny Jiang will discuss a newly developed technology to Read More...
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Bioinformatics
06/20/2024 - Clustered heat maps are widely used for visualizing patterns in molecular profiling data. But traditional, static heat maps have significant limitations when applied to large datasets (1000s of elements per axis). Presented in this Read More...
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Bioinformatics
Work through DNAnexus? Find a nice cancer data set for 16S and shotgun Divide into two workshops or courses? Course structure or workshop structure? Amplicon processing and analysis (5 week course) (4 weeks) 1. Talk by Greg Caparaso? 1. Read More...
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Bioinformatics
Microbiome Course Course Outline Work through DNAnexus? Find a nice cancer data set for 16S and shotgun Divide into two workshops or courses? Course structure or workshop structure? Amplicon processing and analysis (5 week course) (4 weeks) 1. Read More...
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Bioinformatics
10/06/2025 - This is the fourth and final part of a four-part workshop series on Parallel Machine Learning Model Training, presented by AIIG co-chair Samar Samarjeet , PhD (NHLBI). Over the course of the workshop, Samar will Read More...
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Bioinformatics
09/29/2025 - This is the third part of a four-part workshop series on Parallel Machine Learning Model Training, presented by AIIG co-chair Samar Samarjeet , PhD (NHLBI). Over the course of the workshop, Samar will cover topics Read More...
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Bioinformatics
09/22/2025 - This is the second part of a four-part workshop series on Parallel Machine Learning Model Training, presented by AIIG co-chair Samar Samarjeet , PhD (NHLBI). Over the course of the workshop, Samar will cover topics Read More...
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Bioinformatics
09/15/2025 - This week we will kick off a four-part workshop series on Parallel Machine Learning Model Training, presented by AIIG co-chair Samar Samarjeet , PhD (NHLBI). Over the course of the workshop, Samar will cover topics Read More...
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Bioinformatics
02/16/2024 - Deep sequencing has emerged as the primary tool for transcriptome profiling in cancer research. Like other high-throughput profiling technologies, sequencing is susceptible to systematic non-biological artifacts stemming from inconsistent experimental handling. A critical initial Read More...
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Bioinformatics
09/06/2023 - With the advancements in single cell and spatial profiling technologies and methods, some of us thought it would be helpful to re-establish a community of end users on campus. We invite those that are Read More...
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Bioinformatics
Un-ordered lists: use * or - - DNA - RNA - protein - metabolite Ordered list: use numbers 1. Obtain sequencing data 2. Perform pre-alignment QC 3. Adapter and/or quality trim 3. Align sequencing data to reference genome 4. Obtain Read More...
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Bioinformatics
02/17/2022 - Our goal is to understand how cellular heterogeneity encodes the molecular structure, function, and regulation of complex biological systems. Primarily using single cell genomics, we analyze systems by profiling their most fundamental units individually & Read More...
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Bioinformatics
10/19/2021 - Hosted by NIH.AI and NVIDIA, this three-hour workshop will offer opportunities to share the latest updates in applying machine learning in medical image analysis and ongoing activities across the National Institutes of Health ( Read More...
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Bioinformatics
04/28/2021 - Register Session Description QIAGEN’s CLC Genomics Workbench enables researchers to analyze Next Generation Sequencing (NGS) data without the use of command line and is a powerful tool for processing microbial data. In this Read More...
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Bioinformatics
04/08/2021 - https://nih-irp-singlecell.github.io/SC-UsersGroup/ Presenter: George Emanuel PhD, Co-founder Vizgen, Director of Technology and Partnerships. Abstract: Biological systems are comprised of numerous cell types, intricately organized to form functional tissues and organs. Cell Read More...
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Bioinformatics
01/07/2021 - Presenter: Gary Patti, Ph.D. Departments of Chemistry, Genetics, and Medicine Washington University in St. Louis It is well established that the metabolism of cancer cells is reprogrammed to support the demands of rapid Read More...
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Bioinformatics
05/12/2020 - This webinar will provide an introduction to RNA-Seq data analysis followed by tutorials of popular RNA-Seq analysis applications. Participants will be prepared to independently run basic RNA-Seq analysis for expression profiling using a “point Read More...
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Confocal
2024 Coutinho, L. L., Femino, E. L., Gonzalez, A. L., Moffat, R. L., Heinz, W. F., Cheng, R. Y. S., Lockett, S. J., Rangel, M. C., Ridnour, L. A. & Wink, D. A. NOS2 and Read More...
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Bioinformatics
01/14/2026 - This presentation will discuss the results of recently conducted large-scale, NIH-funded trials exploring the clinical utility, economic value, and diagnostic limitations of whole genomic sequencing at birth. Incorporating global efforts to expand access and Read More...
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Bioinformatics
06/03/2025 - Class Description Introduction to RNA-Seq data analysis Step-by-step live demonstration of RNA-Seq analysis using the Galaxy platform What You’ll Learn: How to independently carry out the basic gene expression Read More...
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Bioinformatics
11/07/2024 - In the era of renewed space exploration, understanding female health risks during spaceflight is essential. This talk focuses on leveraging NIAID's ImmPort and NASA's GeneLab data using computational and systems biology to Read More...
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Bioinformatics
09/25/2024 - Please join us on Wednesday, September 25, 2024, where Gina Kuffel, B.S., and Steph Singleton, M.S., will demo the newly launched Clinical and Translational Data Commons (CTDC). As the newest addition to NCI's Read More...
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Bioinformatics
07/11/2024 - Please join us for this special event featuring three speakers on the topic of Single-Cell Spatial Transcriptomics. George Zaki, Ph.D., Director, Applied Scientific Computing, BACS, The Frederick National Lab for Cancer Research, NCI/ Read More...
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Bioinformatics
06/13/2024 - The schedule for this week consists of one presentation: Lorenz Adlung, UMC Hamburg-Eppendorf, will discuss: scMod: Marrying machine learning and deterministic modelling of longitudinal single-cell data Single-cell-based methods such as flow cytometry or single-cell Read More...
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Bioinformatics
05/07/2024 - Galaxy is a scientific workflow, data integration, data analysis, and publishing platform that makes computational biology accessible to research scientists that do not have computer programming experience. This workshop will introduce RNA-seq data analysis Read More...
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Bioinformatics
02/29/2024 - The Consortium of Metabolomics Studies (COMETS) is a partnership of researchers from around the globe that promotes collaboration among prospective cohort studies that follow participants for a range of outcomes and perform metabolomic profiling Read More...
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Bioinformatics
The QIIME2 platform can be used for different types of -omics data. For this course, we will be focusing on targeted amplicon sequencing of the 16S rRNA gene. The 16S rRNA gene (~1500 bp) codes for Read More...
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Bioinformatics
12/14/2023 - NIDAP , the NIH Integrated Data Analysis Platform, is a cloud-based, collaborative data aggregation and analysis platform that hosts user-friendly bioinformatics workflows and other component analysis and visualization tools. The NCI CCR Collaborative Bioinformatics Resource ( Read More...
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Bioinformatics
12/06/2023 - NIDAP, the NIH Integrated Data Analysis Platform, is a cloud-based and collaborative data aggregation and analysis platform. The NIDAP platform hosts user-friendly bioinformatics workflows (Bulk RNA-Seq, scRNA-Seq, Digital Spatial Profiling) and other component analysis Read More...
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Bioinformatics
NCI scientists have many choices available to them for bioinformatic analyses of Next Generation Sequencing (NGS) data. While some require expertise in programming, others provide a more user-friendly, point-and-click interface. These options include programs for Read More...
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Bioinformatics
High resolution single cell profiling assays have provided an unprecedented view of many biological systems and processes, but the spatial context in which this biology is occurring is often crucial. Spatial profiling, including spatial transcriptomic Read More...
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Bioinformatics
05/12/2023 - Galaxy is a scientific workflow, data integration, data analysis, and publishing platform that makes computational biology accessible to research scientists that do not have computer programming experience. This workshop will introduce RNA-seq data analysis Read More...
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Bioinformatics
03/23/2023 - This afternoon workshop will give attendees an understanding of how single cell technologies are used to study cancer. To start us off, Mike Kelly , head of the Single Cell Analysis Facility (SCAF), will give Read More...
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Bioinformatics
11/14/2022 - During this webinar, the Genomic Data Commons ’ (GDC’s) Drs. Zhenyu Zhang and Bill Wysocki will review the different types of harmonized data that the GDC makes available for the cancer research community. The Read More...
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Bioinformatics
11/01/2022 - Learn how to get started on using QIAGEN’s Ingenuity Pathway Analysis (IPA) to quickly identify biological relationships, mechanisms, pathways, functions and diseases most relevant to experimental datasets. IPA is cited in tens of Read More...
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Bioinformatics
09/15/2022 - Learn how to get started on using QIAGEN’s Ingenuity Pathway Analysis (IPA) to quickly identify biological relationships, mechanisms, pathways, functions and diseases most relevant to experimental datasets. IPA is cited in tens of Read More...
Web Page
Bioinformatics
09/01/2022 - Learn how to get started on using QIAGEN’s Ingenuity Pathway Analysis (IPA) to quickly identify biological relationships, mechanisms, pathways, functions and diseases most relevant to experimental datasets. IPA is cited in tens of Read More...
Web Page
Bioinformatics
06/15/2022 - Learn how to get started on using QIAGEN’s Ingenuity Pathway Analysis (IPA) to quickly identify biological relationships, mechanisms, pathways, functions and diseases most relevant to experimental datasets. IPA is cited in tens of Read More...
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Bioinformatics
05/25/2022 - This training will provide an introduction to RNA-seq data analysis followed by tutorials showing the use of popular RNA-seq analysis packages and preparing participants to independently run basic RNA-Seq analysis for expression profiling. The Read More...
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Bioinformatics
04/20/2022 - During this seminar, Dr. Clemens Grassberger will highlight: current computational and mathematical approaches for modeling the impact of radiotherapy on the immune system, and how to design the next generation of combination trials. The Read More...
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Bioinformatics
02/17/2022 - Rahul Satija, D.Phil., Core Faculty Member, New York Genome Center, Associate Professor of Biology, Center for Genomics and Systems Biology, New York University (NYU), Associate Faculty, Institute for Systems Genetics, NYU Langone Medical Read More...
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Bioinformatics
02/16/2022 - For our next CDSL webinar we will have a guest lecture by Dr. Leng Han from the Center for Epigenetics and Disease Prevention at Texas A&M University. Abstract: Despite advancements in Read More...
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Bioinformatics
02/07/2022 - Learn how to get started on using QIAGEN’s Ingenuity Pathway Analysis (IPA) to quickly identify biological relationships, mechanisms, pathways, functions and diseases most relevant to experimental datasets. IPA is cited in tens of Read More...
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Bioinformatics
11/17/2021 - The webinar will highlight how Chromium Single Cell Solutions and Visium Spatial Solutions can uncover molecular insights, dissect cell-type differences, investigate the adaptive immune system, detect novel subtypes and biomarkers, and map the epigenetic Read More...
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Bioinformatics
09/01/2021 - Learn how to get started on using QIAGEN’s Ingenuity Pathway Analysis (IPA) to quickly identify biological relationships, mechanisms, pathways, functions and diseases most relevant to experimental datasets. IPA is cited in tens of Read More...
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Bioinformatics
08/11/2021 - Registration is required to join this event. If you have not registered, please do so now. Efforts are underway to characterize cancer cell lines and identify their genetic and pharmacological vulnerabilities, but integration is Read More...
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Bioinformatics
05/18/2021 - Register Session Description This training will provide an introduction to RNA-seq data analysis followed by tutorials showing the use of popular RNA-seq analysis packages and preparing participants to independently run basic RNA-Seq analysis for Read More...
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Bioinformatics
04/14/2021 - Register Session Description Learn how to get started on using QIAGEN’s Ingenuity Pathway Analysis (IPA) to quickly identify biological relationships, mechanisms, pathways, functions and diseases most relevant to experimental datasets. IPA is cited Read More...
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Bioinformatics
03/17/2021 - Register/Join The focus of this webinar will be on two aspects of integrative analysis and translational research in the field of estrogen receptor-positive (ER+) breast cancer research. Namely, Dr. Meenakshi Anurag will discuss Read More...
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Bioinformatics
02/11/2021 - Register QIAGEN’s Ingenuity Variant Analysis (IVA) has been replaced by QIAGEN Clinical Insight Interpret – Translational (QCII-T), which combines analytical tools and integrated content to help you rapidly identify and prioritize variants by drilling Read More...
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Bioinformatics
01/21/2021 - Registration: https://cbiit.webex.com/cbiit/onstage/g.php?MTID=ec7d9bf4c9b10ea1a5dd4ba4383bfede7 Although much MacVector functionality is targeted at DNA analysis, a large number of features Read More...
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Bioinformatics
11/05/2020 - Register Learn how to get started on using QIAGEN’s Ingenuity Pathway Analysis (IPA) to quickly identify biological relationships, mechanisms, pathways, functions and diseases most relevant to experimental datasets. IPA is cited in tens Read More...
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Bioinformatics
10/07/2020 - QIAGEN’s Ingenuity Variant Analysis (IVA) combines analytical tools and integrated content to help you rapidly identify and prioritize variants by drilling down to a small, targeted subset of compelling variants based on published Read More...
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Bioinformatics
08/21/2020 - Abstract: Machine learning (ML) has emerged as an essential tool for building models which can be used to predict clinical outcomes for age-related diseases. A significant challenge of ML is knowing which algorithms and Read More...
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Bioinformatics
05/28/2020 - Learn how to get started on using QIAGEN’s Ingenuity Pathway Analysis (IPA) to quickly identify biological relationships, mechanisms, pathways, functions and diseases most relevant to experimental datasets. IPA is cited in tens of Read More...
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Bioinformatics
05/18/2020 - This training will provide an introduction to RNA-seq data analysis followed by tutorials showing the use of popular RNA-seq analysis packages and preparing participants to independently run basic RNA-Seq analysis for expression profiling. The Read More...
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Bioinformatics
05/29/2025 - Prostate cancer exhibits significant intratumoral heterogeneity, driving a spectrum of phenotypes ranging from indolent disease to aggressive metastasis, challenging risk stratification and treatment. A key feature of this heterogeneity is clonal diversity, encompassing both Read More...
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Bioinformatics
05/19/2025 - Immunotherapy has the potential to revolutionize the way we treat cancer, but a key challenge has been finding ways to tailor that therapy to the right patient at the right time. Attend this webinar, Read More...
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Bioinformatics
Long read sequencing was recently named 2022’s method of the year by Nature Methods . Long read sequencing technologies, those that generate sequence reads with lengths of 10s of kilobases or longer have several advantages over Read More...
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Bioinformatics
01/22/2025 - Join us for a one-hour talk investigating tumor signatures in the BRCA dataset by utilizing the CCBR Single-Cell RNA-seq Workflow on NIDAP. This talk will take you through an analysis of a publicly available Read More...
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Bioinformatics
10/24/2024 - Recent advances in artificial intelligence (AI) have revolutionized the use of hematoxylin and eosin (H&E)-stained tumor slides for precision oncology, enabling data-driven approaches to predict molecular characteristics and therapeutic outcomes. In Read More...
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Bioinformatics
The Advanced Biomedical Computational Science (ABCS) group focuses on applications of bioinformatics, computational and data science, and artificial intelligence to support NCI researchers. ABCS provides: • Subject matter expertise in genomics, proteomics, and imaging. • Machine learning/ Read More...
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Bioinformatics
03/29/2024 - This event is sponsored by an organization outside of the NIH; it is listed here due to the nature of the presented topics and their appeal to the NCI community. Description: Recent developments in Read More...
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Bioinformatics
This course was designed to teach the basics of targeted amplicon data processing and analysis using the QIIME2 platform. Attendees will learn how to format data and metadata, import data, demultiplex sequences, trim sequences, denoise Read More...
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Bioinformatics
Course Overview This course was designed to teach the basics of targeted amplicon data processing and analysis using the QIIME2 platform. Attendees will learn how to format data and metadata, import data, demultiplex sequences, trim Read More...
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Bioinformatics
Let's submit a batch job. We are going to download data from the Sequence Read Archive (SRA) , a public repository of high throughput, short read sequencing data. We will discuss the SRA a bit Read More...
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Bioinformatics
02/17/2023 - Dr. Brendan Miller is a post-doctoral research fellow at Johns Hopkins University in the Department of Biomedical Engineering. On Friday Feb 17, 1:00-2:00 PM, he will be discussing some tools he has recently helped develop Read More...
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Bioinformatics
10/26/2022 - In partnership with NCI’s Cancer Moonshot SM Initiative, the Society for Immunotherapy of Cancer (SITC) and the Big Data and Data Sharing Committee are hosting the eighth of nine webinars that make up Read More...
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Bioinformatics
10/19/2022 - Welcome to the Microbiome Analysis with QIIME 2 course series! This course series was designed to teach the basics of targeted amplicon data processing and analysis using the QIIME 2 platform. Attendees will learn how to Read More...
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Bioinformatics
09/27/2022 - Speaker: Neil L. Kelleher, Ph.D. Walter and Mary E. Glass Professor of Molecular Biosciences Professor of Chemistry in the Weinberg College of Arts and Sciences Professor of Medicine (Hematology & Oncology) in Read More...
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Bioinformatics
08/03/2022 - Abstract: Liver cancer, comprising mainly hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA), is one of the deadliest cancers in the world, with a five-year survival rate less than 20%. Immunotherapy has emerged as a promising Read More...
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Bioinformatics
06/29/2022 - During this webinar, Computational Biologist Dr. Eytan Ruppin will present on “SELECT,” a computational approach that aims to identify clinically relevant synthetic lethal interactions, thereby harnessing them to predict patient response to cancer therapy Read More...
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Bioinformatics
05/17/2022 - Metabolomic and multi-omic data are increasingly being collected in basic, preclinical, and clinical research studies. Interpretation of these data though remains challenging. Common challenges include the difficulty in identifying metabolites and assigning unique identifiers, Read More...
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Bioinformatics
01/12/2022 - Recent technological advances in science provide novel opportunities to unravel the complex biology of diseases. Immunological changes in translational settings are often highly dynamic and involve multiple interconnected biological systems. We will discuss a Read More...
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Bioinformatics
09/22/2021 - Registration is required. During this upcoming webinar, Dr. Yanjun Qi will demonstrate AttentiveChrome, an attention-based deep learning approach that uses a unified architecture to model and interpret interactions and dependencies among the chromatin factors Read More...
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Bioinformatics
04/21/2021 - Register Here Inherited and environmental influences can put people at greater risk of cancer and impact their response/resistance to treatment. In this presentation, Dr. Eliezer Van Allen will describe how a patient’s Read More...
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Bioinformatics
04/20/2021 - Abstract: Single-cell genome-wide profiling offers an approach to map transitional cell states during cell differentiation, disease onset, and drug response. Lineage-tracing, in which cells are labeled with hereditary markers, offers an approach to establishing Read More...
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Bioinformatics
02/17/2021 - Speaker is Dr. Michal Linial from the Hebrew University of Jerusalem, Israel. Abstract: Incredible progress has also been made in the field of cancer genetics with the sequencing and molecular profiling of tens of Read More...
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Bioinformatics
11/30/2020 - Register Meeting ID: 918 4307 1125 One tap mobile +13017158592,,91843071125# US (Washington D.C) +19294362866,,91843071125# US (New York) Dial by your location +1 301 715 8592 US (Washington D.C) +1 929 436 2866 US (New York) +1 312 626 6799 US (Chicago) +1 346 248 7799 US (Houston) +1 669 900 6833 US (San Jose) +1 253 215 8782 US (Tacoma) Meeting Read More...
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Bioinformatics
06/28/2020 - The overarching goal of our work is to implement data analysis and informatics tools for integration of biological mass spectrometry data (proteomics and metabolomics) with genomic / transcriptomic information to advance cancer research. We are Read More...
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Bioinformatics
Listed below are the video recordings of past BTEP events (classes, seminars, workshops). Videos are hosted on various servers and may play slightly differently. Some videos may be downloaded for local viewing. Recorded Videos of Read More...
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Bioinformatics
Most BTEP courses include detailed course materials including lesson content, additional resources, and lesson associated data. These course materials are listed here so that learners can easily return to and review concepts taught in class Read More...
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Bioinformatics
The computational chemistry and protein modeling team in the Advanced Biomedical Computational Science (ABCS) group provides novel solutions in structural modeling and computational chemistry. Computational scientists in the group collaborate with NCI researchers by using Read More...
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Bioinformatics
One particular critique of differential expression in single cell RNASeq analysis is p-value "inflation," where the p-values get so small that there are far too many genes exist with p-values below 0.05, even after Read More...
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Bioinformatics
1. Introduction and Learning Objectives This tutorial has been designed to demonstrate common secondary analysis steps in a scRNA-Seq workflow. We will start with a merged Seurat Object with multiple data layers representing multiple samples that Read More...
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Bioinformatics
As you can see from the image, there are several accessor functions to access the data from the object: assays() - access matrix-like experimental data (e.g., count data). Rows are genomic features (e.g., Read More...
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Bioinformatics
Lesson 2: Getting Started with QIIME2 Lesson Objectives Obtain sequence data and sample metadata Import data and metadata Discuss other useful QIIME2 features including view QIIME2, provenance tracking, and the QIIME2 forum. DNAnexus DNAnexus provides a Read More...
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Bioinformatics
Objectives To explore Bioconductor, a repository for R packages related to biological data analysis. To better understand S4 objects as they relate to the Bioconductor core infrastructure. To learn more about a popular Bioconductor S4 Read More...
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Bioinformatics
Lesson 5: Working on Biowulf Lesson 4 Review Flags and command options Wildcards ( * ) Tab complete Accessing user history with the "up" and "down" arrows cat , head , and tail Working with file content (input, Read More...
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Bioinformatics
Managing Bioinformatics Projects with Jupyter Lab Learning Objectives After this class, participants will have obtained the foundation needed to start using Jupyter Lab as an all-in-one place to maintain code, output, and other description of Read More...