Search Results for: panel optimization

Total end-to-end system for single-cell research [embed]https://youtu.be/vMzhSzg1rUw[/embed] The BD Rhapsody Single-Cell Analysis system empowers and streamlines your research with a complete system of tools, including reagents and analysis software, Read More...

The Center for Inherited Disease Research (CIDR)'s  mission is to support the genetics community by providing high-quality, cutting-edge genomics services and technologies in order to expand our understanding of disease and catalyze discoveries that Read More...

The Mass Cytometry Core (MCC) provides access to cutting-edge platforms and expert technical support for high-dimensional single-cell analysis and spatial proteomic profiling. A central expertise of the core is Imaging Mass Cytometry (IMC), which allows Read More...

October 6, 2022 crex.nih.gov CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Science & Technology Seminars and Training Events Upcoming Seminars and Educational Opportunities The following Read More...

The Biological Products Core provides the AIDS research community with high-quality purified preparations of various strains of Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV), economically prepared by leveraging the economy of scale. Materials Read More...

The Chemistry and Synthesis Center (CSC) of the National Heart, Lung, and Blood Institute (NHLBI) provides IRP scientists with targeted imaging probes and chemical tools that help accelerate cell-based assays, in vivo imaging studies, and Read More...

The CCR Genomics Core is located in Building 41 on the NIH Bethesda campus. The primary goal of the Core is to provide investigators from CCR/NCI and other NIH Institutes access to genomic technologies and Read More...

The NIH Biowulf Cluster provides researchers with a world-class system to assist in solving complex biomedical problems as diverse as gene variation in worldwide human populations, deep learning to model protein structures, and PET brain Read More...

The CCR Building 41 Flow Cytometry Core is a full-service facility within the Center for Cancer Research that supports over 150 users representing 26 laboratories. The Core Facility provides instrument and software training, technical expertise, assay development, and Read More...

CREx News & Updates August 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGHLIGHTS Learn more about services from the NHLBI Read More...

The Biophysics Core’s mission is to provide support in the study of macromolecular interactions, dynamics, and stability by offering consultations, training, professional collaborations, and instrument access. General Services Multi-technique molecular interaction studies, Kinetic and Read More...

The OSTR offers cutting-edge technology platforms to the CCR scientific community through centralized facilities. The videos accessed through this page are designed to introduce the various scientific methodologies OSTR makes available through the cores on Read More...

The NIH Metabolomics Consortium (NIH-MC) is a shared research resource that performs metabolomics analysis (and related small molecule research) for investigators at all Institutes and Centers across the NIH Intramural Research Program. The NIH-MC is Read More...

CREx News & Updates November 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight FACILITY HIGLIGHTS Learn more about services from the NINDS Quantitative Magnetic Resonance Imaging Core. NINDS Read More...

Our operational objectives are to provide state-of-the-art OMICS technologies in support of the Genetics Branch (GB) investigators and collaborators. Research Services Wet Lab Single cell isolation from fresh, frozen, and FFPE tissue, DNA/RNA extractions Read More...

[tabby title="Home"] About NICE-NIH Intramural CryoEM Consortium  NIH Intramural CryoEM Consortium (NICE) serves intramural investigators in all NIH IC’s. NICE provides access to state-of-the-art Titan Krios cryo-electron microscopes for atomic-resolution structure determination of Read More...

01/19/2021 - Overview Are you interested in improving your machine or deep learning models? You often cannot be sure you've developed the best model without performing hyperparameter optimization. In this talk, we will explain what Read More...

Objectives Combine multiple plots into a single figure Learn how to use patchwork and cowplot The primary purpose of this lesson is to learn how to combine multiple figures into a single multi-panel figure using Read More...

05/13/2020 - During this virtual panel discussion, members of the Advanced Biomedical Computational Science (ABCS) group will discuss their experiences with use of data science in biomedical research. The panel discussion will cover: Types of research Read More...

Multi-figure panel Objectives Combine multiple plots into a single figure Learn how to use patchwork and cowplot The primary purpose of this lesson is to learn how to combine multiple figures into a single multi-panel Read More...

Objectives Combine multiple plots into a single figure Learn how to use aspects of cowplot and patchwork The primary purpose of this lesson is to learn how to combine multiple figures into a single multi-panel Read More...

04/27/2023 - Scientific journals almost always have limits on the number of figures that can be included in a publication. Don't fret, in the 6th and final lesson of the Data Visualization with R course Read More...

Scientific journals almost always have limits on the number of figures that can be included in a publication. Don't fret, in lesson 6, we will focus on generating sub plots and multi plot figure panels Read More...

03/24/2020 - Members of the Advanced Biomedical Computational Science (ABCS) group will discuss their experiences with use of data science in biomedical research.

05/18/2022 - During the May Accelerating Therapeutics for Opportunities in Medicine (ATOM) Webinar Series, discover how computing and machine learning can accelerate molecular optimization for cancer and infectious disease therapeutics. The  ATOM Consortium  is a public-private Read More...

01/04/2021 - Abstract: Phenotypic heterogeneity in cancer is often caused by different patterns of genetic alterations. Understanding such phenotype-genotype relationships is fundamental for the advance of personalized medicine. In this talk, I will present a computational Read More...

05/27/2025 - Agentic AI is a class of artificial intelligence that acts autonomously to make decisions and take actions to achieve specific goals. During this event, the participants will discuss the emerging role of AI agents Read More...

There are many complementary R packages related to creating publishable figures using ggplot2. Check out the packages cowplot and ggpubr . Cowplot is particularly great for providing functions that facilitate arranging multiple plots in a grid Read More...

#Setting a theme my_theme

Combine multiple plots into a single figure Learn how to use aspects of cowplot and patchwork The primary purpose of this lesson is to learn how to combine multiple figures into a single multi-panel figure Read More...

We can modify many aspects of the figure legend using the function guide() . Let's see how that works and go ahead and customize some theme arguments. Notice that the legend position is specified in Read More...

We want to use this in a multi-panel figure in a later lesson, so let's go ahead and save it to a file that will hold a single R object (.rds). saveRDS(plot_de, & Read More...

There are many complementary R packages related to creating publishable figures using ggplot2. Check out the packages cowplot and ggpubr . Cowplot is particularly great for providing functions that facilitate arranging multiple plots in a grid Read More...

08/25/2021 - This introductory course teaches the basics of deep learning and of different types of deep learning networks through a set of hands-on biological examples implemented in Keras, one example per class. Class #3 will focus Read More...

::: {.cell} #Setting a theme my_theme <- theme_bw() + theme( panel.border = element_blank(), axis.line = element_line(), panel.grid.major = element_line(size = 0.2), panel.grid.minor = element_line(size = 0.1), text = element_text( Read More...

01/28/2026 - Navigating Risk in Sharing Cancer Data: Sharing cancer data accelerates scientific discovery and promotes innovation across disciplines, which brings complex ethical, legal, and procedural challenges. This panel will share practical experiences; current Read More...

Clustering is used to group cells by similar transcriptomic profiles. Seurat uses a graph based clustering method. You can read more about it here . The first step is to compute the nearest neighbors of each Read More...

The R community is extensive and getting help is now easier than ever with a simple web search. If you can't figure out how to plot something, give a quick web search a try. Read More...

Load in the comma separated file "./data/countB.csv" and save to an object named gcounts . {{Sdet}} Solution } gcounts `...1` colnames ( gcounts )[ 1 ] ## 1 Tspan6 703 567 867 71 970 242 ## 2 TNMD 490 482 18 342 935 469 ## 3 DPM1 921 797 622 661 8 500 ## 4 SCYL3 335 216 222 774 979 793 ## 5 FGR 574 574 515 584 941 344 ## 6 CFH 577 792 672 104 192 936 ## 7 FUCA2 798 766 995 27 756 546 ## 8 GCLC 822 874 923 705 667 522 ## 9 NFYA 622 793 918 868 334 64 {{Edet}} Plot the Read More...

09/19/2023 - The NIH is home to a number of groups aimed at supporting bioinformatics, genomics, computational biology and various related topics. Many of these groups meet regularly to host talks or provide training opportunities, while Read More...

09/18/2023 - The NIH is home to a number of groups aimed at supporting bioinformatics, genomics, computational biology and various related topics. Many of these groups meet regularly to host talks or provide training opportunities, while Read More...

08/24/2023 - Attend this virtual junior investigator session and hear Oak Ridge National Lab’s Dr. Adam Spannaus and Stanford’s Dr. Chenchen Zhu describe how they use analyses and AI models Read More...

Journal Impact Factor Number of Figures Nature Cancer 60.72 5-8 Science 47.73 6 Cancer Cell 31.74 8 Journal of Clinical Oncology 44.54 6 JAMA Oncology 31.78 5 Cell Host and Microbe 21.02 7 Example Multi-figure panel from Zhang et al.(2022). Longitudinal single-cell RNA-seq analysis reveals stress-promoted Read More...

The R community is extensive and getting help is now easier than ever with a simple web search. If you can't figure out how to plot something, give a quick web search a try. Read More...

03/23/2023 - The upcoming presentations will showcase research from different Cancer Moonshot initiatives that support the 10 recommendations of the Blue Ribbon Panel report . They will inform the community about the progress of Cancer Moonshot-funded projects, provide Read More...

01/26/2023 - This seminar series showcases research from different Cancer Moonshot initiatives that support the 10 recommendations of the Blue Ribbon Panel Report. These presentations will inform the community about the progress of Cancer Moonshot–funded projects, Read More...

11/17/2022 - This seminar series showcases research from different Cancer Moonshot initiatives that support the 10 recommendations of the Blue Ribbon Panel Report. These presentations will inform the community about the progress of Cancer Moonshot–funded projects, Read More...

10/12/2022 - Join us for a panel discussion with the 7 generalist repositories participating in the NIH Generalist Repository Ecosystem Initiative (GREI). Learn about common features and capabilities across repositories as well as repositories that support specific Read More...

07/28/2022 - This seminar series showcases research from different Cancer Moonshot initiatives that support the 10 recommendations of the  Blue Ribbon Panel  report. These presentations will inform the community about the progress of Cancer Moonshot–funded projects, Read More...

11/04/2021 - Abstract:  Existing human genome assemblies have almost entirely excluded highly repetitive sequences within and near centromeres, limiting our understanding of their organization, evolution, and essential role in chromosome segregation. Now, the first complete, telomere-to-telomere Read More...

05/27/2021 - Register here This seminar series showcases research from different Cancer Moonshot initiatives that support the 10 recommendations of the  Blue Ribbon Panel  report. These presentations will inform the community about the progress of Cancer Moonshot– Read More...

08/21/2020 - Abstract: Machine learning (ML) has emerged as an essential tool for building models which can be used to predict clinical outcomes for age-related diseases. A significant challenge of ML is knowing which algorithms and Read More...

01/09/2020 - Description In this course, learn how to solve a real-world use case with machine learning and produce actionable results using Amazon SageMaker. This course teaches you how to use Amazon SageMaker to cover the Read More...

06/27/2017 - NGS Series Open Forum: Meet the Bioinformatics Experts You are invited to a Q & A session with a panel of bioinformatics analysts, most of whom were presenters at the BTEP NGS Workshop Read More...

01/13/2026 - The past decade has witnessed thriving cell atlas research activities in elucidating human cell types and their organization principles. The NIH BRAIN Initiative launched a pilot 3-year BRAIN Initiative Cell Census Consortium (BICCC) in 2014, Read More...

11/12/2024 - NCI staff are welcome to register for an upcoming Childhood Cancer Data Initiative (CCDI) webinar: "Live Demo: National Childhood Cancer Registry (NCCR) Data Platform." Join the NCCR Technical Lead Johanna Goderre, M. Read More...

11/12/2024 - Join us at the upcoming hybrid NIH BRAIN NeuroAI Workshop on November 12 and 13, with virtual access to in-person panels and discussions at the NIH Campus in Bethesda, MD. Artificial intelligence (AI) is reshaping technology Read More...

10/15/2024 - On October 15th-16th, 2024, the NCI Office of Data Sharing (ODS) is hosting the Annual Data Sharing Symposium titled  Driving Cancer Advances through Impactful Research  inside the Clinical Read More...

05/28/2024 - NCI is launching the virtual Cancer AI Conversations series featuring multiple perspectives on timely topics and themes in artificial intelligence for cancer research!  Each event features short talks from 2-4 subject matter Read More...

05/17/2024 - The NIH Artificial Intelligence (AI) Symposium will take place on Friday, May 17th, 2024, in Masur Auditorium in Building 10 on the Bethesda NIH campus. This event is open to all NIH members - registration and Read More...

05/15/2024 - To register to attend, you must log in to your SITC Cancer Immunotherapy CONNECT account. Don’t have an account?  Create a free one . Join Dr. Karchin of the Johns Read More...

05/02/2024 - To register to attend, you must log in to your SITC Cancer Immunotherapy CONNECT account. Don’t have an account?  Create a free one . Join Dr. Mullin of the Roswell Read More...

03/26/2024 - NCI is launching the virtual Cancer AI Conversations series featuring multiple perspectives on timely topics and themes in artificial intelligence for cancer research!  Each event features short talks from 2-4 subject matter Read More...

Objectives Review the grammar of graphics template. Learn about the statistical transformations inherent to geoms. Learn more about fine tuning figures with labels, legends, scales, and themes. Learn how to save plots with ggsave() . Review Read More...

01/23/2024 - NCI is launching the virtual Cancer AI Conversations series featuring multiple perspectives on timely topics and themes in artificial intelligence for cancer research!  Each event features short talks from 2-4 subject matter Read More...

01/16/2024 - To register to attend, you must log in or create a free SITC Cancer Immunotherapy CONNECT account. It’s your last chance to register and learn about the cutting edge of computational immuno-oncology through Read More...

Help Session Lesson 4 Plotting with ggplot2 For the following plots, let's use the diamonds data ( ?diamonds ). The diamonds dataset comes in ggplot2 and contains information about ~54,000 diamonds, including the price, carat, color, clarity, and Read More...

We previously stored FASTQC results for the HBR and UHR raw sequencing data in the ~/biostar_class/hbr_uhr/QC directory (recall that ~ denotes home directory). So before getting started, change into this folder. cd ~/ Read More...

07/18/2023 - To register to attend, you must log in or create a free account. Continue to learn about cutting-edge computational immuno-oncology through a partnership between NCI and the Society for Immunotherapy of Cancer (SITC)! In Read More...

06/28/2023 - To register to attend, you must log in or create a free account. Do you want to better your communication on data science  technologies and analyses with cancer immunotherapy researchers? If so, Read More...

High resolution single cell profiling assays have provided an unprecedented view of many biological systems and processes, but the spatial context in which this biology is occurring is often crucial. Spatial profiling, including spatial transcriptomic Read More...

The cowplot package provides various features that help with creating publication-quality figures, such as a set of themes, functions to align plots and arrange them into complex compound figures, and functions that make it easy Read More...

Let's draw an image on here, just to show that we can add one. There are two options. We can add an image as if it was another figure or we can simply draw Read More...

The plot above is looking pretty good, but there are many more features that can be customized to make this publishable or fit a desired style. Changing non-data elements (related to axes, titles subtitles, gridlines, Read More...

When you have a lot of colors and you want to keep these colors consistent, you can use the following convenient functions to set a name attribute for a vector of colors. Let's do Read More...

Course Overview Welcome to the Data Visualization with R Series A series of lessons designed to introduce learners to the R package ggplot2 This course will include a series of lessons for scientists with beginner Read More...

How do we ultimately get our figures to a publishable state? The bread and butter of pretty plots really falls to the additional non-data layers of our ggplot2 code. These layers will include code to Read More...

Objectives Review the grammar of graphics template. Learn about the statistical transformations inherent to geoms. Learn more about fine tuning figures with labels, legends, scales, and themes. Learn how to save plots with ggsave() . Review Read More...

11/17/2022 - Join Icahn School of Medicine at Mount Sinai’s Dr. Zeynep Gümüş to learn about a user-friendly tool she and her team are developing to enable researchers of all computational skill levels to Read More...

11/16/2022 - Attend this webinar to hear a moderated, five-person panel expand on the presentation, “Perspectives on CMS Linkage for Cancer Research in Cohort Studies.” This presentation is from the recent 2022 Annual Meeting of the NCI Read More...

04/05/2022 - Welcome to the Data Visualization with R course series ! Here, we hope to help you establish the foundations for generating publication quality plots in R. We will mostly be using ggplot2 ( https://ggplot2.tidyverse. Read More...

12/17/2021 - Register Now Faculty: Yi Xing, PhD – Children's Hospital of Pennsylvania/University of Pennsylvania; NCI Cancer Moonshot IOTN Moderator: Kellie N. Smith, PhD – Johns Hopkins School of Medicine Target Audience This series will serve Read More...

11/17/2021 - Register Now Faculty: Joao Xavier, PhD – Memorial Sloan Kettering Cancer Center; NCI CSBC Moderator: Matthew J. Reilley, MD – University of Virginia Target Audience This series will serve as an excellent resource for all stakeholders Read More...

You have to VPN using Cisco AnyConnect Secure Mobility Client . Click Connect button and follow usual instructions. Following NoMachine Installation for Biowulf , double click the connection shortcut. You should see something like below. Fill in Read More...

Running RStudio on Biowulf with NoMachine Using NoMachine to run Rstudio on Biowulf has the benefit of accessing data on the Biowulf/Helix drives. This comes at the cost of setup time and slower responsiveness. Read More...

11/04/2021 - Meeting Link: https://cbiit.webex.com/cbiit/j.php?MTID=mf0f44a00dfd24b954e3b3574894b21c4 Abstract:  Existing human genome assemblies have almost entirely excluded highly repetitive sequences within and near Read More...

10/20/2021 - Register Now Faculty: Joao Xavier, PhD – Memorial Sloan Kettering Cancer Center; NCI CSBC Moderator: Matthew J. Reilley, MD – University of Virginia Target Audience This series will serve as an excellent resource for all stakeholders Read More...

09/08/2021 - Register Now Faculty: Bing Zhang, PhD – BCM, NCI CPTAC Moderator: Carsten Krieg, PhD – Medical University of South Carolina Target Audience This series will serve as an excellent resource for all stakeholders interested in expanding Read More...

08/10/2021 - Register Now Faculty: Evan Newell, PhD – Fred Hutchinson Cancer Institute Moderator: Carsten Krieg, PhD – Medical University of South Carolina Target Audience This series will serve as an excellent resource for all stakeholders interested in Read More...

07/15/2021 - Register Now Faculty: Michael Angelo, MD, PhD – Stanford University, Moonshot Cancer Atlas Moderator: Carsten Krieg, PhD – Medical University of South Carolina Target Audience This series will serve as an excellent resource for all stakeholders Read More...

06/17/2021 - Register Now Faculty: Dana Pe’er, PhD – Memorial Sloan Kettering Cancer Center; NCI Cancer Moonshot HTAN Moderator: Daniel Wells, PhD – Immunai Target Audience This series will serve as an excellent resource for all stakeholders Read More...

05/27/2021 - Register Now Faculty:   Shannon McWeeney, PhD – Oregon Health & Science University; NCI Cancer Moonshot DRSN Moderator:   Santosh Putta, PhD Target Audience This series will serve as an excellent resource for all stakeholders interested Read More...

05/14/2021 - The National Institute of Allergy and Infectious Diseases (NIAID) is excited to advance discovery and innovation in infectious diseases and immune-mediated disorders research by leveraging data and data science approaches. Towards this end, NIAID Read More...

05/11/2021 - Register Now Faculty: Eliezer M. Van Allen, MD – Harvard University/Dana-Farber Cancer Institute/BROAD; NCI Cancer Moonshot IOTN Moderator: Kellie N. Smith, PhD – Johns Hopkins School of Medicine Target Audience This series will serve Read More...

03/29/2021 - For coming Monday's CDSl webinar, we'll be hosting Dr. Yun Liu from Google Health. Abstract: This talk will briefly cover two categories of our work: deep learning to identify dermatology conditions from Read More...

11/13/2020 - New computational opportunities and challenges have emerged within the cancer research and clinical application fields, as the size, source and complexity of cancer datasets have grown. Simultaneously, advances in computational capabilities, with exceptional growth Read More...

07/30/2020 - A panel of scientists with expertise in Single-Cell RNA-Seq will answer your questions on analysis of Single-Cell RNA-Seq data. Questions must be submitted in advance of the meeting by Weds, July 15. Please submit your Read More...

07/23/2020 - A panel of scientists with expertise in Single-Cell RNA-Seq will answer your questions about Single-Cell RNA-Seq experimental design. Please submit your question by July 15, to https://btep.ccr.cancer.gov/question/single_cell_rna_ Read More...

07/09/2020 - The recent breakthroughs in high-throughput technologies have resulted in a vast amount of big-data resources. However, it remains a significant challenge to transfer the knowledge from the public data to a new research project Read More...

10/10/2019 - Multiple sample analysis, data integration across multiple experiments, and technologies 10:00 – 11:00 AM scRNA-seq batch effect correction, differential analysis,  gene set enrichment and network analysis (Abdalla Abdelmaksoud, Vicky Chen) 11:05 – 12:00 PM Trajectory analysis (Abdalla Abdelmaksoud) 1:00 –   2:30 PM Single Read More...

01/23/2017 - The Bioinformatics Training and Education Program (BTEP), Office of Science and Technology Resources (OSTR) is excited to announce a series of workshops focused on the analysis of next-generation sequencing (NGS) data. The in-depth, comprehensive Read More...

  Update: Please contact your IC representative to get access to the Anaconda Business license as it has transitioned from enterprise to seat-based licensing. For questions, email anaconda@nih.gov. Anaconda ( https://www.anaconda. Read More...

Listed below are the video recordings of past BTEP events (classes, seminars, workshops). Videos are hosted on various servers and may play slightly differently. Some videos may be downloaded for local viewing. Recorded Videos of Read More...

Learning Objectives This tutorial was designed to demonstrate common secondary analysis steps in a scRNA-Seq workflow. We will start with a merged Seurat Object with multiple data layers representing multiple samples. Throughout this tutorial we Read More...

Introduction to ggplot2 Objectives Learn the ggplot2 syntax. Build a ggplot2 general template. By the end of the course, students should be able to create simple, pretty, and effective figures. Data Visualization in the tidyverse Read More...

In lesson 9, we learned that reference genomes came in the form of FASTA files, which essentially store nucleotide sequences. In this lesson, we will learn about the FASTQ file, which is the file format that Read More...

Lesson 10: Introducing the FASTQ file and assessing sequencing data quality Before getting started, remember to be signed on to the DNAnexus GOLD environment. Lesson 9 Review In the previous lesson, we explored the reference genomes and Read More...

Lesson 11: Merging FASTQ quality reports and data cleanup Before getting started, remember to be signed on to the DNAnexus GOLD environment. Lesson 10 Review In the previous lesson, we learned about the structure of the FASTQ Read More...

Scatter plots and plot customization Objectives Learn to customize your ggplot with labels, axes, text annotations, and themes. Learn how to make and modify scatter plots to make fairly different overall plot representations. Load a Read More...

Introduction to ggplot2 Objectives Learn how to import spreadsheet data. Learn the ggplot2 syntax. Build a ggplot2 general template. By the end of the course, students should be able to create simple, pretty, and effective Read More...

12/19/2016 - iPathwayGuide is a gene and protein expression analysis tool that uses a systems biology approach to identify significantly impacted pathways, gene ontology terms, diseases, and predicted microRNAs based on the given gene or protein Read More...

03/18/2015 - This workshop will cover basics of exome-seq analysis including downstream interpretation of variants using a variety of open-source and commercial webtools (Golden Helix, IGV, Ingenuity Variant Analysis, GeneGrid (Genomatix), MuPit/Cravat). Day 1 - AM (9:30 Read More...

03/18/2014 - The Cancer Genome Atlas (TCGA) is a large-scale study that has catalogued genomic data accumulated from more than 20 different types of cancer including mutations, copy number variation, mRNA and miRNA gene expression, and DNA Read More...