Frederick, MD
Collaborative
The Biopharmaceutical Development Program (BDP) provides resources for the development of investigational biological agents. The BDP supports feasibility through development and Phase I/II cGMP manufacturing plus regulatory documentation.The BDP was established in 1993. We Read More...
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Bioinformatics
01/15/2025 - For inquires send email to staff@hpc.nih.gov Next edition of the NIH HPC monthly Zoom-In Consults! All Biowulf users, and all those interested in using the systems, are invited to stop by Read More...
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Bioinformatics
05/15/2024 - For inquires send email to staff@hpc.nih.gov Next edition of the NIH HPC monthly Zoom-In Consults! All Biowulf users, and all those interested in using the systems, are invited to stop by Read More...
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Bioinformatics
05/10/2024 - Please join us for the May Data Sharing and Reuse Seminar featuring Dr. Ali Loveys and Fiona Meng from FI Consulting. They will be sharing their presentation on Laying the Foundation for AI-Ready Data. Read More...
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Bioinformatics
When using SingleR, the 3 primary parameters are the experimental dataset, the reference dataset, and the labels being used. Continuing with the main labels of the MouseRNASeq dataset on the full dataset looks like this: annot = Read More...
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Bioinformatics
09/08/2023 - Hybrid Seminar Friday, September 8, 2023 • 9:00-10:00 a.m. Building 549 Auditorium (In-person attendance encouraged) Speaker: Brian Kelsall, M.D. Senior Investigator, Mucosal Immunobiology Section Laboratory of Molecular Immunology National Institutes of Allergy Read More...
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Bioinformatics
04/09/2025 - We will share the summary and feedback from Enhancing Data Reuse in Cancer Research Workshop Series hosted by our office in June and July 2024. Join us as we explore: feedback from NCI Data Reuse Read More...
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Bioinformatics
Much like pseudobulk differential expression, the RNA expression can be collapsed into pre-defined components, such as the clusters, if it is believed that cell-to-cell variation is inducing too much confusion in the labeling. This collapsing Read More...
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Bioinformatics
01/27/2025 - NCI CCR Liver Cancer Program Seminar Series Dr. Sethupathy is professor of physiological genomics and chair of the Department of Biomedical Sciences at Cornell University. He leads a research lab focused on genome-scale and Read More...
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Bioinformatics
10/24/2024 - NIH Text Mining and Natural Language Processing SIG is pleased to welcome you to this special event featuring two extraordinary speakers focused on the applications of Deep Learning in Computational Biology. & Read More...
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Bioinformatics
Another important data structure in R is the data matrix. Data frames and data matrices are similar in that both are tabular in nature and are defined by dimensions (i.e., rows (m) and columns ( Read More...
Frederick, MD
Collaborative
The Antibody Characterization Laboratory (ACL) is the laboratory responsible for the development of well-characterized monoclonal antibody reagents. The NCI’s Office of Cancer Clinical Proteomics Research funds ACL as a resource to the entire cancer Read More...
Bethesda, MD
Trans NIH Facility
The Metabolic Clinical Research Unit (MCRU) opened in 2007 as a key component of the Strategic Plan for NIH Obesity Research . The NIDDK worked closely with the Clinical Center to design the Unit, which houses state-of-the-art Read More...
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Back Services: Biophysics Facility offers Octet as an open-access instrument. First-time users must complete a short training session before gaining access to the instrument reservation calendar. Training includes a full analysis of a Read More...
Bloomington, IN
Repositories
Trans NIH Facility
The Bloomington Drosophila Stock Center (BDSC) collects, maintains, and distributes genetically defined strains of Drosophila melanogaster for research and education. The BDSC supports a large, worldwide community of scientists using Drosophila as a model organism Read More...
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Bioinformatics
07/15/2025 - Thi i the final le on in the cour e Introductory R for Novice : Introduction to Data Wrangling. Thi le on will how attendee how to join multiple data frame and tran form and Read More...
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Bioinformatics
04/16/2025 - Updated Location: ATRF, Frederick MD, Main Auditorium What to bring: Laptop capable of connecting to internet via NIH wifi For questions or to register, please contact Amy Stonelake ( amy.stonelake@nih.gov ) Read More...
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Bioinformatics
04/15/2025 - What to bring: Laptop capable of connecting to internet via NIH wifi Are you looking to expand the reach of your sequencing to enable what long read technologies can provide?& Read More...
Web Page
Bioinformatics
04/15/2025 - What to bring: Laptop capable of connecting to internet via NIH wifi Are you looking to expand the reach of your sequencing to enable what long read technologies can provide?& Read More...
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Bioinformatics
01/15/2025 - Science and Technology Group: Work in Progress Seminar Series 2025
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Bioinformatics
11/15/2024 - Hands-on workshop using R and Seurat to analyze an example spatial transcriptomics dataset
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Bioinformatics
Dataquest licenses are no longer available. If you currently have a Dataquest license, you can continue using it until Sept 15, 2025. The Coursera platform contains thousands of courses developed by experts all over the world and Read More...
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Bioinformatics
The base data type (e.g., numeric, character, logical, etc.) and the class (dataframe, matrix, etc.) will be important for what you can do with an object. Learn more about an object with the following: Read More...
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Bioinformatics
A vector is a collection of values that are all of the same type (numbers, characters, etc.) --- datacarpentry.org c() - used to combine elements of a vector When you combine elements of different Read More...
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Bioinformatics
The following sources inspired this content: https://www.sc-best-practices.org https://hbctraining.github.io/scRNA-seq_online/ https://bioconductor.org/books/3.15/OSCA.basic/
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Bioinformatics
Single cell RNASeq is a remarkably powerful tool for analyzing populations of cells that can be recovered from various experiments. Clustering and cell type annotation can be used to distinguish different populations with a level Read More...
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Bioinformatics
There are many tools and strategies available for cell annotation. I've included a non-comprehensive list for your convenience: Azimuth SingleR scType Garnet Digital Cell Sorter . Cell Marker 2.0 Here is a list of resources that Read More...
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Bioinformatics
library(tidyverse) # dplyr and ggplot2; CRAN library(Seurat) # Seurat toolkit; CRAN library(hdf5r) # for data import; CRAN library(patchwork) # for plotting; CRAN library(presto) # for differential expression; Github library(glmGamPoi) # for sctransform; Bioconductor library( Read More...
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Bioinformatics
The following sources inspired this content: https://www.sc-best-practices.org https://hbctraining.github.io/scRNA-seq_online/ https://bioconductor.org/books/3.15/OSCA.basic/ This is only a small subset of tools available to single cell RNASeq. Read More...
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Bioinformatics
02/15/2024 - This lesson will be divided into two parts. Part 1 will introduce Bioconductor, an R package repository for the analysis of biological data. Part 2 will introduce RMarkdown and Quarto for report generation with R.
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Bioinformatics
A geom is the geometrical object that a plot uses to represent data. People often describe plots by the type of geom that the plot uses. --- R4DS There are multiple geom functions that Read More...
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Bioinformatics
Vectors are probably the most used commonly used object type in R. A vector is a collection of values that are all of the same type (numbers, characters, etc.). The columns that make up a Read More...
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Bioinformatics
select() requires the data frame followed by the columns that we want to select or deselect as arguments. #select the gene / transcript, logFC, and FDR corrected p-value #first argument is the df followed by columns Read More...
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CCR Office of Science and Technology Resources (OSTR) The Center for Cancer Research (CCR) Office of Science and Technology Resources (OSTR) explores and evaluates the latest technologic advancements and then makes them available to all Read More...
Bethesda, MD
Trans NIH Facility
The Pathology Service, Division of Veterinary Resources (DVR), Office of Research Services (ORS), provides diagnostic gross and histopathologic evaluation of any species of laboratory animals used in the NIH Intramural Research Program due to morbidity, Read More...
Frederick, MD
Collaborative
In order to meet increasing demands from both NIH intramural and extramural communities for access to a small angle X-ray scattering (SAXS) resource, the Center for Cancer Research (CCR) under the leadership of Drs. Jeffrey Read More...
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October 6, 2022 crex.nih.gov CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Science & Technology Seminars and Training Events Upcoming Seminars and Educational Opportunities The following Read More...
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Back Services: Biophysics Facility offers DLS as an open-access instrument. First-time users must complete a short training session before gaining access to the instrument reservation calendar. Training includes DLS analysis of small- and large-molecular size Read More...
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Bioinformatics
09/29/2025 - Plea e u e thi link to acce overview, regi tration, and other information: http ://event .cancer.gov/nci/od -data-jamboree Childhood cancer i a rare di ea e with ~15,000 ca e diagno ed Read More...
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Bioinformatics
07/09/2025 - From image analy i to federated learning and multimodal modeling, generative AI can be u ed to tudy ob ervational ucce ion acro cale and data type . At DCEG' Data cience and Engineering Re Read More...
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Bioinformatics
07/08/2025 - Thi le on will introduce the " plit-apply-combine" approach to data analy i and the key player in the dplyr package u ed to implement thi type of workflow.
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Bioinformatics
06/05/2025 - In the econd cla of the Python Introductory Education erie , participant will tart to dive into Python. Participant will walk away with knowledge of common Python data type and tructure a well a how Read More...
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Bioinformatics
Anaconda ( https://www.anaconda.com/ ) is a package manager and distributor for a wide array of data science software. Package managers are ideal for scientists who conduct analysis on a personal computer as they eliminate Read More...
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Bioinformatics
04/25/2025 - In partnership with the NIH Clinical Center's Biostatistics and Clinical Epidemiology Service (BCES), the NIH Library is offering this two-part online training for non-statisticians interested in understanding the basic, intuitive thinking behind the Read More...
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Bioinformatics
04/15/2025 - The Demystifying Medicine Series, jointly sponsored by FAES and NIH, includes presentations on pathology, diagnosis, and therapy in the context of major disease problems and current research. Primarily directed toward PhD students, clinicians and Read More...
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Bioinformatics
The computational chemistry and protein modeling team in the Advanced Biomedical Computational Science (ABCS) group provides novel solutions in structural modeling and computational chemistry. Computational scientists in the group collaborate with NCI researchers by using Read More...
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Bioinformatics
01/23/2025 - AI in Medicine: Focus on Deep Learning in Medical Genomics This series invites Principal Investigators, Senior Scientists, and Senior Clinicians to share cutting-edge research and developments in their fields. Each session includes a 20-30 Read More...
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Bioinformatics
01/15/2025 - This one-hour online training will cover the fundamentals, applications, and ethical considerations of Artificial Intelligence (AI). Attendees will explore key topics such as machine learning, deep learning, data handling, and real-world AI applications across Read More...
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Bioinformatics
01/15/2025 - The goal is to support broad data sharing and reuse that benefits the entire cancer community. This event will cover best practices for accessing controlled data and highlight updates on the new NIH security Read More...
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Bioinformatics
01/15/2025 - This session of the BTEP Coding Club will demonstrate how to use the R package “survival” to conduct a survival analysis of an example dataset. Senior Programmer and Analyst, Duncan Donohue, PhD, will cover Read More...
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Bioinformatics
01/14/2025 - In this talk, we will cover the basics of survival analysis as a statistical methodology developed for censored data. Special emphasis will be on visualizing survival data, comparing survival-time distributions for subject groups, and Read More...
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Bioinformatics
11/15/2024 - In partnership with the NIH Clinical Center's Biostatistics and Clinical Epidemiology Service (BCES), the NIH Library is offering classes geared to cover general concepts behind statistics and epidemiology. This four-part lecture series will Read More...
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Bioinformatics
11/06/2024 - Join Our Training on Spatial Omics Data Analysis with MAWA (Multiplex Analysis Web Apps). Want to learn how to process and analyze your spatial proteomics/transcriptomics data? Join us for four virtual hour-long sessions Read More...
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Bioinformatics
10/29/2024 - Join Our Training on Spatial Omics Data Analysis with MAWA (Multiplex Analysis Web Apps). Want to learn how to process and analyze your spatial proteomics/transcriptomics data? Join us for four virtual hour-long sessions Read More...
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Bioinformatics
10/22/2024 - Join Our Training on Spatial Omics Data Analysis with MAWA (Multiplex Analysis Web Apps). Want to learn how to process and analyze your spatial proteomics/transcriptomics data? Join us for four virtual hour-long sessions Read More...
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Bioinformatics
10/16/2024 - The CRDC will celebrate its 10th anniversary with this one-and-a-half-day event highlighting its accomplishments and looking ahead to exciting initiatives. We are planning many informative sessions and report-outs on new work, including our AI Read More...
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Bioinformatics
10/15/2024 - Join Our Training on Spatial Omics Data Analysis with MAWA (Multiplex Analysis Web Apps). Want to learn how to process and analyze your spatial proteomics/transcriptomics data? Join us for four virtual hour-long sessions Read More...
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Bioinformatics
10/15/2024 - This one-hour online training will cover techniques on locating biomedical research articles, patents, NIH-funded research projects, genetic information, and print and electronic books related to animal models and model organisms. This training will also Read More...
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Bioinformatics
10/15/2024 - On October 15th-16th, 2024, the NCI Office of Data Sharing (ODS) is hosting the Annual Data Sharing Symposium titled Driving Cancer Advances through Impactful Research inside the Clinical Read More...
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Bioinformatics
09/23/2024 - Come to the Fair! In the morning session, several different groups will speak about their training and education programs. The afternoon session will be devoted to learning about research using AI across Read More...
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Bioinformatics
08/15/2024 - Qiagen’s CLC Genomics Workbench is a point-and-click software for analyzing multi-omics sequencing data including variant analysis, RNA sequencing, and ChIP sequencing. This class will demonstrate variant analysis using this software. Participants will be Read More...
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Bioinformatics
06/20/2024 - Dr. Irizarry will share findings demonstrating limitations of current workflows that are popular in single cell RNA-Seq data analysis. Specifically, he will describe challenges and solutions to dimension reduction, cell-type classification, and statistical significance Read More...
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Bioinformatics
Some tools have been described in the previous session (see here ). Today, we will be focusing on the SingleR tool, which also requires the celldex package . In short, SingleR operates by comparing your current dataset Read More...
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Bioinformatics
Integration is the process of aligning the same cell types across samples, treatments, data sets, batches, etc. Clustering should represent biological differences and not technical artifacts. Integration is not always necessary. You should run through Read More...
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Bioinformatics
Rather than relying on the above steps ( NormalizeData() , FindVariableFeatures() , and ScaleData() ), we are going to proceed with a newer method ( SCtransform ) instead. This method uses Pearson residuals for transformation, which better accounts for the overall Read More...
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Bioinformatics
This tutorial has been designed to demonstrate common secondary analysis steps in a scRNA-Seq workflow. We will start with a merged Seurat Object with multiple data layers representing multiple samples that have already been filtered Read More...
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Bioinformatics
Clustering is used to group cells by similar transcriptomic profiles. Seurat uses a graph based clustering method. You can read more about it here . The first step is to compute the nearest neighbors of each Read More...
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Bioinformatics
In this tutorial, we are using data from Nanduri et al. 2022, Epigenetic regulation of white adipose tissue plasticity and energy metabolism by nucleosome binding HMGN proteins , published in Nature Communications . The raw count matrices are Read More...
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Bioinformatics
05/22/2024 - This seminar provides an overview of differential expression testing with Seurat. Topics to be covered include preparing data for differential gene expression, d ifferential gene analysis between specific groups, d ifferential gene analysis for Read More...
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Bioinformatics
05/15/2024 - Generalist repositories offer NIH researchers a flexible, trusted resource to share data for which there is no appropriate discipline specific repository as well as to share many other research outputs valuable for reproducibility and Read More...
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Bioinformatics
05/15/2024 - To register to attend, you must log in to your SITC Cancer Immunotherapy CONNECT account. Don’t have an account? Create a free one . Join Dr. Karchin of the Johns Read More...
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Bioinformatics
05/15/2024 - In this one-hour webinar, you'll get a demonstration of DNASTAR Lasergene Software. DNASTAR offers software solutions for molecular biology, protein analysis, and genomics. This presentation will focus on an overview of the applications Read More...
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Bioinformatics
04/23/2024 - What’s the difference between “regular” statistics (i.e., what you may have been using in the past several years) and the “new” Bayesian Read More...
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Bioinformatics
Step 1: Goto https://www.globus.org to log in by clicking on the "LOG IN" icon at the top right of the pages. After logging in, select organziational affiliation, which is National Institutes Read More...
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Bioinformatics
After this class, participants will Become familiar analyzing single cell RNA sequencing data using Partek Flow including Importing of data into a Partek Flow project QA/QC, filtering, and normalizing of single cell RNA data Read More...
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Bioinformatics
02/15/2024 - This one-hour introductory class provides researchers with an overview of online resources for locating research datasets, data repositories, and data publications for data sharing and re-use. Participants will learn search strategies for locating datasets Read More...
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Bioinformatics
Given the following R code: numbers
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Bioinformatics
This course will include a series of lessons for individuals new to R or with limited R experience . The purpose of this course is to introduce the foundational skills necessary to begin to analyze and Read More...
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Bioinformatics
Data structures are objects that store data. Previously, we learned that vectors are collections of values of the same type . A vector is also one of the most basic data structures. Other common data structures Read More...
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Bioinformatics
The data type of an R object affects how that object can be used or will behave. Examples of base R data types include numeric, integer, complex, character, and logical. R objects can also have Read More...
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Bioinformatics
There is an approach to data analysis known as "split-apply-combine", in which the data is split into smaller components, some type of analysis is applied to each component, and the results are combined. Read More...
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Bioinformatics
Let's use some functions. a. Use sum() to add the numbers from 1 to 10. {{Sdet}} Solution{{Esum}} sum ( 1 : 10 ) {{Edet}} b. Compute the base 10 logarithm of the elements in the following vector and save to an Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Intramural Core Resources NHGRI Flow Cytometry Core The Core performs high quality single cell analysis through the Read More...
Frederick, MD
Core Facility
The research conducted within the Synthetic Biologics Core (SBC) Facility has a dual role: Generate chemical biology tools and drug candidates for molecular targets identified by NCI research groups, Develop novel effective methods and tools Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New Resources on CREx Trans-NIH Metabolomics Core (TNMC) The TNMC is a shared research resource that provides targeted Read More...
Web Page
CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Intramural CryoEM (NICE) Consortium NICE provides NCI, NIAID, NIEHS, NICHD, NIDCR, NEI, and NIA investigators with Read More...
Frederick, MD
Collaborative
The Chemical Synthesis Group is a component of the Chemical Biology Laboratory. This facility provides synthetic chemistry resources and expertise to the NCI Intramural community. The facility’s capabilities include: Providing expertise, consultation, and experience Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Extramural Common Fund Resources Metabolomics Workbench Developed by the NIH Metabolomics Common Fund's National Metabolomics Data Repository ( Read More...
Web Page
Back Services: Biophysics Facility offers MST as an open-access instrument. First-time users must complete a short training session before gaining access to the instrument reservation calendar. Training includes the KD determination of a Read More...
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Home Biophysics Core Technologies Biophysics Core Services The Biophysics Core The Biophysics Core Facility (BCF) was established in 2008 in the NHLBI as an advanced service laboratory providing expertise, training, consultations, and instrument access for intramural Read More...
Frederick, Maryland
Core Facility
CLIA-Certified Technologies Offered: Fragment Analysis for Micro-satellite Instability Detection, Pharmacoscan Array for Pharmacogenomics, Mutation Detection for PCR and Sanger Sequencing, DNA extraction from whole blood, saliva, FFPE tissues, buccal swabs, nails, hair, PBMCs, buffy coats, Read More...
Frederick, MD
Collaborative
The NMR Facility for Biological Research operates six NMR spectrometers with proton resonance frequencies from 850 to 500 MHz. Three of the highest field spectrometers (850, 700, 600) are equipped with higher sensitivity cryoprobes optimized for high-resolution multi-dimensional and relaxation Read More...
Frederick, MD
Core Facility
Clinical Support Laboratory – Flow Cytometry Section is a laboratory specializing in providing immunophenotyping support of NCI intramural clinical trials, though assessments may also be performed using cells from Non-human primates and other species. The CSL Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Technology Event Biophysical Methods for Protein Interactions Monday, May 15 – Friday, May 19, 2023 This workshop will review the strategies of Read More...
Bethesda, MD
Trans NIH Facility
The NIH Clinical Center Pharmacy Department provides pharmaceutical care to inpatients and outpatients on NIH intramural research protocols at the NIH Clinical Center. The Clinical Center facility encompasses 200 inpatient beds, 93 day-hospital stations, and 15 clinics. Clinical Read More...
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Back Services: Biophysics Facility offers ITC calorimeters as open-access instruments. First-time users must complete a short training session before gaining access to the instrument reservation calendar. Training includes performing a test experiment and Read More...
Rockville, MD
Trans NIH Facility
NISC’s role within NHGRI, and more broadly across NIH, aims to advance genome sequencing and its many applications, with a goal not simply to produce sequence data, but to produce the infrastructure required to Read More...
Frederick, MD
Core Facility
Repositories
The Mouse Modeling Core assists NIH investigators by generating and preserving genetically-engineered mouse strains. Services include scientific consultation, gene-targeting in mouse embryonic stem cells, micro-injection of nucleic acids, proteins, or ES cells into mouse embryos, Read More...
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The Staff Scientists/Clinicians (SSSC) Technical Enrichment Program (STEP) was established to provide SSSC’s an opportunity to compete for funding to gain comprehensive training in state-of-the-art techniques available through CCR Cores and Facilities. The Read More...
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September 8, 2022 crex.nih.gov CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Science & Technology Seminars and Training Events Upcoming Seminars and Educational Opportunities The following Read More...
Frederick, MD
Core Facility
Molecular Cytogenetics Core Facility facilitates the assessment of structural and numerical genomic changes in pre-cancer and cancer research models. This core provides comprehensive support for the cytogenetic analysis of cells from human and research animal Read More...
Rockville, MD
Collaborative
Repositories
Proteomic Data Common (PDC) represents the NCI’s largest public repository of proteogenomic comprehensive tumor datasets, essentially a Proteogenomic Cancer Atlas. It was developed to advance our understanding of how proteins help shape the risk, Read More...
Web Page
CREx News & Updates June 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGHLIGHTS Visit here to learn about services from Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New NIH Resource Spotlight The NIH Lab Managers Working Group have developed a new NIH-wide database of cold Read More...
Bethesda, MD
Core Facility
Trans NIH Facility
The PET Department, CC, functions as a core facility that supports basic, translational, and clinical research using PET. It is a vertically integrated facility, with resources to produce positron-emitting radionuclides, manufacture PET radiopharmaceuticals in a Read More...
Bethesda, MD
Collaborative
The CCR Collaborative Bioinformatics Resource (CCBR) is a centrally funded resource group which provides a mechanism for CCR researchers to obtain many different types of bioinformatics assistance to further their research goals. The group has Read More...
Bethesda, MD
Collaborative
Repositories
The National Cancer Institute (NCI) is developing a national repository of Patient-Derived Models (PDMs) comprised of patient-derived xenografts (PDXs), patient-derived organoids (PDOrg), and in vitro patient-derived tumor cell cultures (PDCs) and cancer-associated fibroblasts (CAFs). These Read More...
Web Page
CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Research Festival The NIH Research Festival highlights the groundbreaking science and the vibrant NIH community driving our Read More...
Bethesda, MD
Trans NIH Facility
The Clinical Image Processing Service (CIPS) offers timely and accurate advanced image processing of diagnostic radiology images for clinical care, research, and training. CIPS’ functions include clinical services and scientific researches. Established Technologies: CIPS can Read More...
Bethesda, MD
Trans NIH Facility
The Science and Technology Research Infrastructure for Discovery, Experimentation, and Sustainability (STRIDES) Initiative The STRIDES Initiative aims to help NIH and its institutes, centers, and offices (ICOs) accelerate biomedical research by reducing barriers in utilizing Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New NIH Resource Resources Derive Greater Insights and Accelerate your Research Using Bioinformatic Tools! CREx is an NIH Read More...
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Back Services: Biophysics Facility offers ZetaView as an open-access instrument. First-time users must complete a short training session before using it for the first time. Training includes instrument calibration and size analysis of a standard Read More...
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Supplemental Technology Award Review System (STARS) Overview STARS Request Form STARS System The Supplemental Technology Award Review System (STARS) is a web-based interface for submission and review of S&S supplement requests by CCR Read More...
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CREx News & Updates July 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Click below to learn how easy it is to navigate the CREx platform. These short videos will Read More...
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CREx News & Updates November 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight FACILITY HIGLIGHTS Learn more about services from the NINDS Quantitative Magnetic Resonance Imaging Core. NINDS Read More...
Bethesda, Maryland
Core Facility
Repositories
The AgingResearchBiobank was officially launched in January 2019 with a mission to provide a state-of-the-art inventory system for the storage, maintenance, and distribution of de-identified biospecimens and associated phenotypic, clinical, and imaging data from numerous NIA-funded Read More...
Bethesda, MD
Core Facility
The CCR Genomics Core is located in Building 41 on the NIH Bethesda campus. The primary goal of the Core is to provide investigators from CCR/NCI and other NIH Institutes access to genomic technologies and Read More...
Web Page
[tabby title="Home"] About NICE-NIH Intramural CryoEM Consortium NIH Intramural CryoEM Consortium (NICE) serves intramural investigators in all NIH IC’s. NICE provides access to state-of-the-art Titan Krios cryo-electron microscopes for atomic-resolution structure determination of Read More...
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Bioinformatics
07/24/2025 - NIDDK Bio tat eminar erie : From Re earch tudy De ign to Collecting, Managing, and Analyzing Data. Learning Objective : 1. To delineate feature of REDCap to upport project management for re earch tudie . 2. To outline Read More...
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Bioinformatics
07/17/2025 - NIDDK Bio tat eminar erie : From Re earch tudy De ign to Collecting, Managing, and Analyzing Data. Learning Objective 1. The learner hould know the difference between ob ervational tudie , clinical trial (drug and non-drug Read More...
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Bioinformatics
07/09/2025 - Thi e ion of the BTEP Coding Club will demon trate the u e of R programming to perform deci ion tree analy i , urvival tree analy i , and random fore t. Thi event Read More...
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Bioinformatics
05/07/2025 - Join Dr. Eytan Ruppin, NCI investigator in the Center for Cancer Research, as he discusses Path2Space, a new and unpublished deep learning approach that predicts spatial gene expression directly from histopathology slides. Spatial Read More...
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Bioinformatics
nf-core is a community effort to generate a curated set of standardized, best-practice, reproducible, documented, NGS analysis pipelines. All these workflows are built using the versatile workflow manager, Nextflow , and have been released under the Read More...
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Bioinformatics
03/13/2025 - UCSC Xena showcases seminal cancer genomics datasets from The Cancer Genome Atlas (TCGA) and the Pan-Cancer Atlas, as well as the Genomic Data Commons, Pan-cancer Atlas of Whole Genomes, and the International Cancer Genome Read More...
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Bioinformatics
Listed below are the video recordings of past BTEP events (classes, seminars, workshops). Videos are hosted on various servers and may play slightly differently. Some videos may be downloaded for local viewing. Recorded Videos of Read More...
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Bioinformatics
12/05/2024 - This one and a half hour online training will provide a demonstration of how to identify cell types based on statistics, visualization, and canonical markers. One Peripheral blood mononuclear cells (PBMCs) sample will be Read More...
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Bioinformatics
10/16/2024 - Dear Colleagues, Thanks to advances in single-cell genomics, researchers can construct large-scale organ atlases, giving you more accurate ways to study genetic mutations and alterations related to drug responses and disease. These Read More...
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Bioinformatics
Congratulations, your experiments have been completed and you have a large amount of data. Now, it’s time to analyze these data. But where do you begin? How can you gain the most meaning from Read More...
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Bioinformatics
Please see https://bioinformatics.ccr.cancer.gov/btep/self-learning/ to sign up for a license. Contact ncibtep@nih.gov with any questions about obtaining a license. Did you know that CCR researchers have access to Read More...
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Bioinformatics
07/25/2024 - This hour and half in-person training will explore the topics of perception and cognition, and how these apply to data visualization. There will also be a discussion on “pre-attentive” properties Read More...
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Bioinformatics
07/24/2024 - This hour and half in-person training will explore the topics of perception and cognition, and how these apply to data visualization. There will also be a discussion on “pre-attentive” properties Read More...
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Bioinformatics
In this tutorial, we will continue to use data from Nanduri et al. 2022, Epigenetic regulation of white adipose tissue plasticity and energy metabolism by nucleosome binding HMGN proteins , published in Nature Communications . As a reminder, Read More...
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Bioinformatics
In this tutorial, we will continue to use data from Nanduri et al. 2022, Epigenetic regulation of white adipose tissue plasticity and energy metabolism by nucleosome binding HMGN proteins , published in Nature Communications . As a reminder, Read More...
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Bioinformatics
Now, that we have clusters, we can use differential expression analysis to uncover markers that define our clusters. These markers can be used to assign cell types to our clusters. First, because we are working Read More...
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Bioinformatics
Following Cell Ranger and/or other pre-processing tools, you will have a gene-by-cell counts table for each sample. The three most popular frameworks for analyzing these count matrices include: R ( Seurat ). Seurat, brought to you Read More...
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Bioinformatics
The Seurat Object is a data container for single cell RNA-Seq and related data. It is an S4 object, which is a type of data structure that stores complex information (e.g., scRNA-Seq count matrix, Read More...
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Bioinformatics
Learning Objectives This tutorial was designed to demonstrate common secondary analysis steps in a scRNA-Seq workflow. We will start with a merged Seurat Object with multiple data layers representing multiple samples. Throughout this tutorial we Read More...
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Bioinformatics
1. Introduction and Learning Objectives This tutorial has been designed to demonstrate common secondary analysis steps in a scRNA-Seq workflow. We will start with a merged Seurat Object with multiple data layers representing multiple samples that Read More...
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Bioinformatics
This lesson provides an introduction to R in the context of single cell RNA-Seq analysis with Seurat. Learning Objectives Learn about options for analyzing your scRNA-Seq data. Learn about resources for learning R programming. Learn Read More...
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Bioinformatics
04/22/2024 - Intended Audience This webinar targets researchers interested in exploring genomic mutation analysis capabilities within the recently introduced NCI Genomic Data Commons (GDC) 2.0 platform. It aims to accommodate individuals interested in analyzing genes and mutations Read More...
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Bioinformatics
04/01/2024 - Embark on a journey of visionary insights! Join us for the launch of the NEI Informatics & Data-Driven Insights: Seminars & Dialogue Opportunities for Vision Health series, hosted by the National Eye Read More...
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Bioinformatics
03/13/2024 - Dear Colleagues, UCSC Xena is a web-based visual integration and exploration tool for multi-omic data and associated clinical and phenotypic annotations. Xena showcases seminal cancer genomics datasets from Read More...
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Bioinformatics
03/05/2024 - This in-person, hands-on training will introduce participants to single cell RNA sequencing analysis using Partek Flow, a point-and-click software for analyzing high dimensional multi-omics sequencing data. At NIH, Partek Flow is hosted on the Read More...
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Bioinformatics
Accessing Partek Flow at NIH and tips for data transfer Learning objectives Instructions for accessing Partek Flow NCI researchers can find instructions for accessing Partek Flow at https://bioinformatics.ccr.cancer.gov/btep/partek-flow-bulk-and-single-cell-rna-seq-data-analysis/ . But Read More...
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Bioinformatics
Course Overview Partek Flow is a start-to-finish solution for analyzing high dimensional multi-omics sequencing data. It is a point-and-click software and is suitable for those who wish to avoid the steep learning curve associated with Read More...
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Bioinformatics
To access the NIH Partek Flow server, go to https://partekflow.cit.nih.gov/flow and enter the user's NIH username and then password. Note User may have selected a password different than that Read More...