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Bioinformatics
02/25/2025 - Quality assessment may reveal low quality sequences and/or contaminations such as adapters in NGS data. Therefore, it is important to perform cleanup to ensure that the input for downstream analyses tools is of Read More...
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Bioinformatics
02/20/2025 - This class will introduce the first step in analyzing NGS data using bulk RNA sequencing as an example. After attending, participants will be able to describe the file format in which NGS data is Read More...
Web Page
Bioinformatics
02/27/2025 - NGS produces millions of sequences per sample and the challenge is to identify where in the genome each sequence came from. Fortunately, there are aligners that help scientists with this task. After this class, Read More...
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Bioinformatics
09/30/2021 - This NIH-FDA sponsored workshop will bring together members of the scientific community to discuss the obstacles and opportunities associated with NGS and radiomics tool development, validation, and regulatory science. NCI presenters include NCI Director, Read More...
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Bioinformatics
09/29/2021 - This NIH-FDA sponsored workshop will bring together members of the scientific community to discuss the obstacles and opportunities associated with NGS and radiomics tool development, validation, and regulatory science. NCI presenters include NCI Director, Read More...
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Bioinformatics
11/06/2012 - Introduction of Next-Generation Sequencing This seminar will provide an overview of Next Generation DNA Sequencing. Highlighting Illumina sequencing technology, and its application in the areas of DNAse-seq, ChIP-seq, and RNA-seq, as well as Genomic Read More...
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Bioinformatics
10/24/2023 - In this session, we will provide an overview of the Next-Generation Sequencing (NGS) capabilities and applications. We will present the workflows and analyses for Illumina short-read, PacBio, and Oxford Nanopore long-read sequencing on Frederick Read More...
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Bioinformatics
04/09/2019 - DNAnexus provides a secure cloud based platform for the analysis, storage and sharing of many different types of genomic data. CCR has recently established a Pilot program to enable CCR researchers to use this Read More...
Web Page
Bioinformatics
04/21/2021 - Register Description: MacVector is a sequence analysis application for macOS computers that provides users with a variety of tools and functions to simplify the analysis, manipulation, assembly, and documentation of DNA and protein sequences. Read More...
Web Page
Bioinformatics
04/14/2021 - Registration: https://cbiit.webex.com/cbiit/onstage/g.php?MTID=ec198bc69667ba131397fb48e0c9b9708 Presenter: Christian Zinser PhD Head of Bioinformativs at Precigen Bioinformatics Germany Description: This presentation will give you Read More...
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Bioinformatics
01/23/2017 - The Bioinformatics Training and Education Program (BTEP), Office of Science and Technology Resources (OSTR) is excited to announce a series of workshops focused on the analysis of next-generation sequencing (NGS) data. The in-depth, comprehensive Read More...
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Bioinformatics
11/29/2012 - The Integrative Genomics Viewer (IGV) is a high-performance viewer that efficiently handles large heterogeneous data sets, while providing a smooth and intuitive user experience at all levels of genome resolution. A key characteristic of Read More...
Web Page
Bioinformatics
01/14/2021 - Registration: https://cbiit.webex.com/cbiit/onstage/g.php?MTID=e968a58127acdb59b961e2ef13865c7ad Description: This workshop will focus on the analysis of Next Generation Sequencing (NGS) data using the Read More...
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Bioinformatics
04/02/2013 - Geneious is an integrated and extensible software platform for the organization, visualization and analysis of DNA and protein sequence information. Researchers can analyze any NGS data alongside traditional Sanger data and combine technologies in Read More...
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Bioinformatics
03/06/2013 - Geneious is an integrated and extensible software platform for the organization, visualization and analysis of DNA and protein sequence information. Researchers can analyze any NGS data alongside traditional Sanger data and combine technologies in Read More...
Web Page
Bioinformatics
04/28/2021 - Register Session Description QIAGEN’s CLC Genomics Workbench enables researchers to analyze Next Generation Sequencing (NGS) data without the use of command line and is a powerful tool for processing microbial data. In this Read More...
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Bioinformatics
04/21/2021 - Registration: https://cbiit.webex.com/cbiit/onstage/g.php?MTID=e51f19be5660107b4b92118dc48be1781 Presenter: Kevin Kendal PhD CEO of MacVector Description: This workshop will focus on the analysis of Next Read More...
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Bioinformatics
10/28/2020 - Register The Sequencing Facility (https://ostr.cancer.gov/resources/fnl-cores/sequencing-facility) is a second and third generation high-throughput sequencing core established by the Center for Cancer Research (CCR). Sequencing Facility’s (SF’s) primary Read More...
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Bioinformatics
04/11/2019 - DNAnexus provides a secure cloud based platform for the analysis, storage and sharing of many different types of genomic data. CCR has recently established a Pilot program to enable CCR researchers to use this Read More...
Web Page
Bioinformatics
Lessons focus on RNA-Seq analysis including experimental design and best practices, quality control, trimming, alignment based methods, feature counts, differential expression analysis, and biological interpretation. Lesson 7 - Introduction to RNA-Seq Lesson 8 - Introduction to Next Read More...
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Bioinformatics
Lessons focus on RNA-Seq analysis including experimental design and best practices, quality control, trimming, alignment based methods, feature counts, differential expression analysis, and biological interpretation. Lesson 6 - Introduction to RNA-Seq Lesson 7 - Introduction to Next Read More...
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Bioinformatics
03/11/2025 - In this class, participants will get hands-on experience with generating and interpreting differential gene expression analysis results from bulk RNA sequencing. In addition, participants will learn to generate common plots used to visualize bulk Read More...
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Bioinformatics
03/06/2025 - This class introduces participants to the first steps to differential expression analysis in bulk RNA sequencing which involves filtering out noise from (ie. genes without expression across samples) and performing QC on the gene Read More...
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Bioinformatics
03/04/2025 - Alignment of RNA sequencing data enables researchers to identify where in the genome each sequence came from. However, it does not inform of how many sequences aligned to each genomic feature such as a Read More...
Web Page
Bioinformatics
RNA-Seq (RNA sequencing), uses next-generation sequencing (NGS) to reveal the presence and quantity of RNA in a biological sample at a given moment. (Wikipedia) Strictly speaking this could be any type of RNA (mRNA, rRNA, Read More...
Web Page
Bioinformatics
Partek Flow (Partek) is a graphical user interface (GUI) based bioinformatics software that is dedicated to the analysis of next generation sequencing (NGS) data. It can perform the analyses listed below. {{Sdet}}{{Ssum}}List of Read More...
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Bioinformatics
Lesson 7 introduced the FASTQ file, which is the format used to store Next Generation Sequencing (NGS) data. Participants also learned about assessing quality of the sequences in FASTQ files using the tool FASTQC. This step Read More...
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Bioinformatics
QIAGEN CLC Genomics Workbench is a graphical user interface (GUI) based bioinformatics software. It houses tools for molecular biology and next generation sequencing (NGS) analysis. CLC genomics workbench functionality includes: Analysis of your NGS data, Read More...
Web Page
Bioinformatics
QIAGEN CLC Genomics Workbench is a graphical user interface (GUI) based bioinformatics software. It houses tools for molecular biology and next generation sequencing (NGS) analysis. CLC genomics workbench functionality includes: Analysis of your NGS data, Read More...
Frederick, MD
Core Facility
The introduction of DNA sequencing instruments capable of producing millions of DNA sequence reads in a single run has profoundly altered the landscape of genetics and cancer biology. Complex questions can now be answered at Read More...
Rockville, MD
Trans NIH Facility
NISC’s role within NHGRI, and more broadly across NIH, aims to advance genome sequencing and its many applications, with a goal not simply to produce sequence data, but to produce the infrastructure required to Read More...
Web Page
Bioinformatics
11/16/2023 - This class will provide a demonstration of how to identify cell types based on statistics, visualization, and canonical markers. One Peripheral blood mononuclear cells (PBMCs) sample will be used to illustrate a basic Single Read More...
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Bioinformatics
09/21/2023 - This is Lesson 3 of the Fall 2023 Introduction to Unix on Biowulf Series . Registering for this class will get you signed up for all four sessions in this course. Please make sure that you can Read More...
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Bioinformatics
08/28/2020 - Speaker: Dr. Christian Zinser, Precigen Bioinformatics Registration The Genomatix Genome Analyzer (GGA) aids in analyzing next generation sequencing (NGS) data from ChIP, RNA, DNA, methylation, or small RNA sequencing. This introductory webinar gives an Read More...
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Bioinformatics
After this course, participants will be able to Log onto the NIH High Performance Compute Cluster Biowulf Navigate the folder and file (directory) structure on a Unix system Work with very large Next Generation Sequencing ( Read More...
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Bioinformatics
After this course, participants will be able to Log onto the NIH High Performance Compute Cluster known as Biowulf Navigate the folder and file (directory) structure on a Unix system Work with very large Next Read More...
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Bioinformatics
CLC Genomics Workbench (Qiagen) is a graphical user interface (GUI) based bioinformatics software. It houses tools for molecular biology and Next Generation Sequencing (NGS) analysis (see Listing of Analysis Functions below). {{Sdet}}{{Ssum}}Listing of Read More...
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The CLIA Molecular Diagnostics Laboratory (CMDL) provides an array of services for groups at the NIH Clinical Center, Fort Detrick, and Hood College, among others. They support cancer- and disease-related research by making Read More...
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Bioinformatics
General questions or comments about the BTEP program or classes should be addressed to: NCIBTEP@nih.gov Desiree Tillo, Ph.D . Staff Scientist desiree.tillo@nih.gov I have a broad research background in bioinformatics Read More...
Web Page
Bioinformatics
12/05/2024 - This one and a half hour online training will provide a demonstration of how to identify cell types based on statistics, visualization, and canonical markers. One Peripheral blood mononuclear cells (PBMCs) sample will be Read More...
Web Page
Bioinformatics
12/03/2024 - This one and a half hour online training will provide a demonstration of how to build a Bulk RNA-Seq data analysis pipeline using a fastq file. Partek Flow Read More...
Web Page
Bioinformatics
03/05/2024 - This in-person workshop will show participants how to identify cell types based on statistics, visualization, and canonical markers. One Peripheral blood mononuclear cells (PBMCs) sample will be used to illustrate a basic Single Cell Read More...
Web Page
Bioinformatics
01/22/2024 - Dear Colleagues, Optical Genome Maps (OGM) provide scaffolding information for large DNA molecules. In this talk, we describe the use of this technology for detecting structural variants and chaining them Read More...
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Bioinformatics
06/29/2023 - Starting with the classic Central Dogma of Molecular Biology, we will look at how each of the components (DNA, RNA, protein) is measured and analyzed. Next-Gen Sequencing (NGS) techniques, analyses tools available, and some Read More...
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Bioinformatics
06/21/2023 - Biowulf is the high-performance computing cluster (HPC) at NIH. In addition to its vast compute power, Biowulf has hundreds of bioinformatics tools and databases for analyzing Next Generation Sequencing (NGS) data. This coding club Read More...
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Bioinformatics
06/22/2022 - Cancer origination and progression is a complex process that can be viewed as a somatic evolutionary progression with clonal cellular expansion(s) driven by accumulation of survival-/evasion-beneficial genomic mutations, alongside constantly changing selective Read More...
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Bioinformatics
05/21/2019 - Next-generation sequencing (NGS) RNA-seq experiments generate millions of reads per run and problems can arise. Before analyzing the data to draw biological conclusions, it is important to perform quality control checks to minimize the Read More...
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Bioinformatics
04/25/2017 - This talk will be an introduction to Methyl-seq, where you will learn about leveraging the power of next-generation sequencing (NGS), both genome-wide and targeted approaches, that can provide insight into methylation patterns at a Read More...
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Bioinformatics
03/29/2017 - The CCR Bioinformatics Training and Education Program (BTEP) is pleased to organize a workshop on Partek Flow for scientists at NCI-Frederick . Partek Flow software is designed specifically for the analysis needs of next generation Read More...
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Bioinformatics
05/28/2013 - Nexus Copy Number is a user-friendly desktop application for analysis and visualization of structural variation (copy number, allelic events, and small sequence variations) from CGH and SNP array- and NGS-generated data. The simple and Read More...
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Bioinformatics
This class will introduce novices to essential Unix commands for getting started in bioinformatics. Unix is an operating system like Windows and MacOS. However, in Unix, users interact with the computer by issuing commands rather Read More...
Web Page
Bioinformatics
Partek Flow is a graphical user interface (GUI) based bioinformatics software that is dedicated to the analysis of next generation sequencing (NGS) data. Why Partek Flow? Partek Flow is compatible with all major genomic formats Read More...
Web Page
Bioinformatics
Partek Flow is a graphical user interface (GUI) based bioinformatics software that is dedicated to the analysis of next generation sequencing (NGS) data. Why Partek Flow? Partek Flow is compatible with all major genomic formats Read More...
Frederick, Maryland
Core Facility
CLIA-Certified Technologies Offered: Fragment Analysis for Micro-satellite Instability Detection, Pharmacoscan Array for Pharmacogenomics, Mutation Detection for PCR and Sanger Sequencing, DNA extraction from whole blood, saliva, FFPE tissues, buccal swabs, nails, hair, PBMCs, buffy coats, Read More...
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NanoString Technology The nCounter® Analysis System is an automated, multi-application, digital detection and counting system which directly profiles up to 800 molecules simultaneously from a single sample using a novel barcoding technology. Profile hundreds of mRNAs, Read More...
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OSTR provides CCR investigators with access to a variety of software licenses for genomic, proteomic, pathway analysis and data visualization tools. These software are funded by OSTR and made available at no cost to CCR Read More...
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Bioinformatics
03/13/2025 - This session will introduce participants to visualizing alignment results from Next Generation Sequences using the Integrative Genomics Viewer (IGV). This step is important as scientists may want to highlight results from certain genomic locations Read More...
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Bioinformatics
09/28/2023 - This is Lesson 4 of the Fall 2023 Introduction to Unix on Biowulf Series . Registering for this class will get you signed up for all four sessions in this course. Please make sure that you can Read More...
Web Page
Bioinformatics
09/14/2023 - This is Lesson 2 of the Fall 2023 Introduction to Unix on Biowulf Series . Registering for this class will get you signed up for all four sessions in this course. Please make sure that you can Read More...
Web Page
Bioinformatics
09/07/2023 - This is Lesson 1 of the Fall 2023 Introduction to Unix on Biowulf Series. Registering for this class will get you signed up for all four sessions in this course. Please make sure that you can Read More...
Web Page
Bioinformatics
RNA-SEQ Overview What is RNASEQ ? RNA-Seq (RNA sequencing), uses next-generation sequencing (NGS) to reveal the presence and quantity of RNA in a biological sample at a given moment. (Wikipedia) Strictly speaking this could be any Read More...
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Bioinformatics
Factor in at least 3 replicates (absolute minimum), but 4 if possible (optimum minimum). Biological replicates are recommended rather than technical replicates. Always process your RNA extractions at the same time. Extractions done at different times lead Read More...
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Bioinformatics
For any NGS experiment you will have to make choices about the following sequencing options. Unfortunately, there is and inverse relationship between accuracy and cost. Read Depth More depth needed for lowly expressed genes Detecting Read More...
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Bioinformatics
06/06/2023 - Welcome to Learning Unix on Biowulf. This course consists of four one-hour lessons that will run weekly on Tuesdays from 1 -2 PM starting May 16. Subsequent lessons will be held on May 23, May 30, and June 6. Read More...
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Bioinformatics
05/30/2023 - Welcome to Learning Unix on Biowulf. This course consists of four one-hour lessons that will run weekly on Tuesdays from 1 -2 PM starting May 16. Subsequent lessons will be held on May 23, May 30, and June 6. Read More...
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Bioinformatics
05/23/2023 - Welcome to Learning Unix on Biowulf. This course consists of four one-hour lessons that will run weekly on Tuesdays from 1 -2 PM starting May 16. Subsequent lessons will be held on May 23, May 30, and June 6. Read More...
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Bioinformatics
05/16/2023 - Welcome to Introduction to Unix on Biowulf. This course consists of four one-hour lessons that will run weekly on Tuesdays from 1 -2 PM starting May 16. Subsequent lessons will be held on May 23, May 30, and Read More...
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Bioinformatics
03/15/2023 - Do you use excel's VLOOKUP function often to merge tables or search for subsets of data in large NGS data files? If so, you may be interested in a more programmatic solution. Join Read More...
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Bioinformatics
BTEP is currently running on-line classes to enable CCR scientists to learn computer and bioinformatics skills remotely. We are using two on-line resources as the basis of each class and have added bi-weekly interactive learning Read More...
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Bioinformatics
02/11/2022 - The seminar is open to the public and registration is required each month. Dr. Hunter Mosely plans to discuss the richness of open data resources in biology and how they can support machine learning Read More...
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Bioinformatics
11/10/2020 - This two-part lecture will provide an overview of RNA-Seq technology, its various application and shortcomings, as well as detailing the steps involved in analyzing the resulting data. Part II This second part of the Read More...
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Bioinformatics
05/21/2019 - This introductory lecture will provide an overview of RNA-Seq technology, its various application and shortcomings, as well as detailing the steps involved in analyzing the resulting data. The specific topics covered include: What is Read More...
Web Page
Bioinformatics
04/12/2019 - DNAnexus provides a secure cloud based platform for the analysis, storage and sharing of many different types of genomic data. CCR has recently established a Pilot program to enable CCR researchers to use this Read More...
Web Page
Bioinformatics
05/09/2018 - Driven by the decreasing costs and increasing performance of next-generation sequencing (NGS) technologies, the amount of publicly available genomic data has grown exponentially in recent years. While most of the analyses of these data Read More...
Web Page
Bioinformatics
12/13/2016 - Driven by the decreasing costs and increasing performance of next-generation sequencing (NGS) technologies, the amount of publicly available genomic data has grown exponentially in recent years. While most of the analyses of these data Read More...
Frederick, MD
Core Facility
The Genomics Technology Laboratory is an integrated, high-throughput molecular biology laboratory focusing on the development of genetics and genomics technologies, data analysis, and information management tools, in support of CCR Investigators. The laboratory develops integrated Read More...
Bethesda, MD
Core Facility
The CCR Genomics Core is located in Building 41 on the NIH Bethesda campus. The primary goal of the Core is to provide investigators from CCR/NCI and other NIH Institutes access to genomic technologies and Read More...
Bethesda, MD
Collaborative
The CCR Collaborative Bioinformatics Resource (CCBR) is a centrally funded resource group which provides a mechanism for CCR researchers to obtain many different types of bioinformatics assistance to further their research goals. The group has Read More...
Bethesda, MD
Collaborative
Our operational objectives are to provide state-of-the-art OMICS technologies in support of the Genetics Branch (GB) investigators and collaborators. Research Services Wet Lab Single cell isolation from fresh, frozen, and FFPE tissue, DNA/RNA extractions Read More...
Rockville, MD
Collaborative
We are a bioinformatics team within the Center for Biomedical Informatics and Information Technology’s (CBIIT’s) Cancer Informatics Branch (CIB)—soon to be referred to as the Informatics and Data Science (IDS) Program. Headed Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx User Survey The CREx Team is carrying out a CREx User Survey. If you haven’t Read More...
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Large STARS can be used to request supplemental funding exceeding $8,000 to offset experimental costs (e.g., core or vendor services or specialized reagents). Applications require detailed scientific and budgetary justification and must be proposed in Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Research Festival The NIH Research Festival highlights the groundbreaking science and the vibrant NIH community driving our Read More...
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Small STARS can be used to request supplemental funding to offset exceptional costs (e.g., core or vendor services or specialized reagents). All requests must be approved for funding before work can commence. Provides 50% cost Read More...
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Bioinformatics
This archive contains past and present issues of the BTEP BioInformatics Bulletin. The BTEP Bioinformatics Bulletin features select upcoming bioinformatics events offered across NIH and is distributed monthly via email to the Center Read More...
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Bioinformatics
The Advanced Biomedical Computational Science (ABCS) group focuses on applications of bioinformatics, computational and data science, and artificial intelligence to support NCI researchers. ABCS provides: • Subject matter expertise in genomics, proteomics, and imaging. • Machine learning/ Read More...
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Bioinformatics
NCI scientists have many choices available to them for bioinformatic analyses of Next Generation Sequencing (NGS) data. While some require expertise in programming, others provide a more user-friendly, point-and-click interface. These options include programs for Read More...
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Bioinformatics
Bioinformatics for Beginners: RNA-Seq Course Description: This course was designed to teach the basic skills needed for bioinformatics, including working on the Unix command line. This course primarily focuses on RNA-Seq analysis. All steps of Read More...
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Bioinformatics
Working with NGS data, bulk RNA-Seq example Who should take this course: Learners who want to understand bulk RNA-Seq experimental and analysis techniques. Pre-requisites: Learners should: be familiar with the GOLD learning environment have beginner Read More...
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Bioinformatics
Syllabus for “Bioinformatics for Beginners" Instructors: Co-Instructors: To participate in these courses, you need a computer, reliable internet connection and a web browser. All classes and help sessions will be held online. This class Read More...
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Bioinformatics
Introduction to Bioinformatics Resources at NCI (06/13, Instructor Amy Stonelake, PhD (BTEP)) In this lesson, attendees will be introduced to the different bioinformatics resources available to them at NCI. This includes: Bioinformatics Training Classes and Events Read More...
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Bioinformatics
Course Overview Course Description A series of 6 stand-alone lessons introducing learners to various aspects of bioinformatics. Lessons will be held on Tuesdays at 1 PM in June and July 2023. You can attend any class, just one Read More...
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Bioinformatics
Unix, what is it, and why should biologists take the time to learn it? The Unix operating system forms the basis of many bioinformatics analyses resources, such as the NIH High Performance Cluster (HPC) Biowulf/ Read More...
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Bioinformatics
09/04/2020 - Speakers: Dave Clements, Galaxy Community Manager, Johns Hopkins University, Steven Weaver, Senior Programmer Analyst, Temple University Galaxy is an open web-based platform for data integration and analysis in the life sciences. Galaxy makes sophisticated Read More...
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Bioinformatics
11/14/2017 - The CCR Office of Science and Technology Resources (OSTR), along with the Bioinformatics Training and Education Program (BTEP), are pleased to organize this event for the CCR scientific community. The primary goal of single Read More...
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Bioinformatics
03/20/2017 - BTEP Workshop on RNA-Seq Data Analysis (2-day) This 2-day workshop, which includes both lecture and hands-on components, will cover the fundamentals of and best practices for RNA-Seq Data Analysis. Learn everything from experimental design Read More...
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Bioinformatics
02/21/2017 - This BTEP Workshop will cover the fundamentals and best practices of Exome-Seq analysis, including downstream interpretation of variants using a variety of in-house and NCI-licensed software solutions. There will be hands-on training on CCBR Read More...
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Bioinformatics
03/08/2016 - BTEP Workshop on Exome-Seq Data Analysis and Variant Annotation (2-day) This workshop will cover the basics and best practices of exome-seq analysis including downstream interpretation of variants using a variety of in-house, open-source and Read More...
Web Page
Bioinformatics
03/18/2015 - This workshop will cover basics of exome-seq analysis including downstream interpretation of variants using a variety of open-source and commercial webtools (Golden Helix, IGV, Ingenuity Variant Analysis, GeneGrid (Genomatix), MuPit/Cravat). Day 1 - AM (9:30 Read More...
Bethesda, MD
Collaborative
Repositories
The NCI Genomic Data Commons (GDC) was established by the NCI Center for Cancer Genomics (CCG) to support the receipt, harmonization, distribution, and analysis of genomic and clinical data from cancer research programs. The GDC Read More...
Bethesda, MD
Trans NIH Facility
The NIH Center for Human Immunology, Inflammation, and Autoimmunity (CHI) is a trans-NIH resource whose mission is to provide a collaborative hub of advanced translational immunology for NIH clinical and pre-clinical studies. This uniquely structured Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New NIH Resource Resources Advance your research with the NIH Mouse Imaging Facility (MIF) The NIH Mouse Imaging Read More...
Bethesda, MD
Core Facility
The Cancer and Inflammation Program – Microbiome and Genetics Core (CIP-MGC) grew out of the former CIP Genetics Core to meet the increasing need for sequencing and analysis of commensal microbiota within CIP and NCI. The Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New Resources on CREx NCI CLIA Molecular Diagnostics Laboratory (CMDL) The NCI CMDL is available to assist all Read More...
Web Page
The Genomics Laboratory (formerly Laboratory of Molecular Technology) is an integrated, high-throughput molecular biology laboratory focusing on the development of genetics and genomics technologies, together with associated laboratory automation systems, data analysis, and information management Read More...
Web Page
CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx User Survey The CREx Team is carrying out a CREx User Survey. We would greatly appreciate Read More...
Web Page
September 8, 2022 crex.nih.gov CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Science & Technology Seminars and Training Events Upcoming Seminars and Educational Opportunities The following Read More...
Bethesda, MD
Core Facility
The rapid advancement of single-cell technology has provided new powerful tools to answer many biological questions, such as identifying new or rare cell populations and characterizing the complexities of tumor heterogeneity. Realizing the great potential Read More...
Web Page
CREx News & Updates December 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight FACILITY HIGLIGHTS Learn more about services from the STRIDES Initiative. VIEW STRIDES INITIATIVE NIH Cores Read More...
Bethesda, MD
Trans NIH Facility
The Center for Inherited Disease Research (CIDR)'s mission is to support the genetics community by providing high-quality, cutting-edge genomics services and technologies in order to expand our understanding of disease and catalyze discoveries that Read More...
Bethesda, MD
Collaborative
Repositories
The National Cancer Institute (NCI) is developing a national repository of Patient-Derived Models (PDMs) comprised of patient-derived xenografts (PDXs), patient-derived organoids (PDOrg), and in vitro patient-derived tumor cell cultures (PDCs) and cancer-associated fibroblasts (CAFs). These Read More...
Web Page
Bioinformatics
Welcome! Welcome to the R Introductory Series! Who: Novices and beginners\ What: A course series introducing R and RStudio. This course will introduce the foundational skills necessary to begin to analyze and visualize data in Read More...
Web Page
Bioinformatics
Generating VCF Files (Simulated data) VCF files are produced by running a variant caller on one or more BAM alignment files. We will download the ebola genome (AF086833) into a "refs" directory, create Read More...
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Bioinformatics
Resources Tertiary Analysis - Biological Meaning Pathway Analysis IPA (Qiagen - CCR License) Future talk Functional Analysis Gene Set Enrichment Analysis (GSEA) https://www.gsea-msigdb.org/gsea/index.jsp DAVID https://david.ncifcrf.gov/ Enrichr Read More...
Web Page
Bioinformatics
Lesson 6: sra-tools, e-utilities, and parallel This page uses some content directly from the Biostar Handbook by Istvan Albert. Lesson 5 Review: The majority of computational tasks on Biowulf should be submitted as jobs: sbatch or swarm Read More...
Web Page
Bioinformatics
Lesson 6: Downloading data from the SRA For this lesson, you will need to login to the GOLD environment on DNAnexus. Lesson 5 Review: The majority of computational tasks on Biowulf should be submitted as jobs: sbatch Read More...
Web Page
Bioinformatics
Data Simulation We'll download a reference sequence from NCBI (AF086833, ebola genome), place it in a refs directory that we create, and create a "bam" index using "bwa". mkdir -p Read More...
Web Page
Bioinformatics
We previously stored FASTQC results for the HBR and UHR raw sequencing data in the ~/biostar_class/hbr_uhr/QC directory (recall that ~ denotes home directory). So before getting started, change into this folder. cd ~/ Read More...
Web Page
Bioinformatics
05/22/2017 - Driven by the decreasing costs and increasing performance of next-generation sequencing (NGS) technologies, the amount of available genomic data has grown exponentially in recent years. While most of the analyses of these data is Read More...
Bethesda, MD
Collaborative
The Pan-Microbial Serology Facility (PMSF) is part of the Center for Cancer Research (CCR) at the National Cancer Institute (NCI). The PMSF focuses on determining individualized pan-microbial immune profiles associated with human diseases including immunological Read More...
Web Page
CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Technology Event Biophysical Methods for Protein Interactions Monday, May 15 – Friday, May 19, 2023 This workshop will review the strategies of Read More...
Rockville, MD
Collaborative
Repositories
The NCI Cloud Resources are components of the NCI Cancer Research Data Commons (CRDC) that bring data and computational power together to enable cancer research and discovery. These cloud-based platforms eliminate the need for researchers Read More...
Web Page
.row { display: flex; justify-content: space-around; align-items: flex-start; margin: 20px; } .column { text-align: center; padding: 10px; width: 30%; } .column img { display: block; margin: 0 auto; width: 150px; height: 150px; } .column strong { display: block; margin-top: 10px; } Background: Intravital microscopy (IVM) Read More...
Frederick, MD
Core Facility
The Advanced Biomedical Computational Sciences (ABCS) group provides technology development, scientific consultation, collaboration and training, research, software development, and high-performance computing support. ABCS encompasses specialized groups focusing on machine learning applied to the interpretation of 2 Read More...
Web Page
CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New NIH Resource Resources Derive Greater Insights and Accelerate your Research Using Bioinformatic Tools! CREx is an NIH Read More...
Bethesda, MD
Trans NIH Facility
The NIH Biowulf Cluster provides researchers with a world-class system to assist in solving complex biomedical problems as diverse as gene variation in worldwide human populations, deep learning to model protein structures, and PET brain Read More...
Frederick, MD
Collaborative
The Center for Advanced Preclinical Research (CAPR) specializes in evaluating the efficacy of preclinical compounds, existing drugs, or biologics (therapeutics) in genetically engineered mouse models, GEM-derived allograft (GDA) models, or patient-derived mouse xenografts (PDX). We Read More...
Frederick, MD
Core Facility
The research conducted within the Synthetic Biologics Core (SBC) Facility has a dual role: Generate chemical biology tools and drug candidates for molecular targets identified by NCI research groups, Develop novel effective methods and tools Read More...
Frederick, MD
Core Facility
OMAL focuses its research and development activities to quantitatively understand the molecular basis of three-dimensional (3D) cell organization, motility, invasion, and differentiation using fixed samples and live, 3D tissue culture models (i.e., translational models). Read More...
Web Page
October 6, 2022 crex.nih.gov CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight NIH Center For Human Immunology, Inflammation, And Autoimmunity (CHI) CHI is a Read More...
Web Page
September 8, 2022 crex.nih.gov CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight Trans-NIH Intramural Sequencing Center (NISC) NISC is a multi-disciplinary genomics facility that Read More...
Bethesda, Maryland
Collaborative
Radiation Oncology Branch is part of CCR. Bioinformatics core is a collaborative resource to support ROB branch and provide service to ROB investigators from NCI and other Institutes access to new technologies, bioinformatics, statistical analysis Read More...
Frederick, MD
Core Facility
NCI LASP Genome Modification Core (GMC) is a CCR-dedicated facility that provides advice, training, and reagents to NCI scientists seeking to utilize CRISPR and other nucleases to generate genome modifications in primary cells, cell lines, Read More...
Web Page
CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More. New Resources on CREx NIMH Human Brain Collection Core (HBCC) The HBCC obtains human brain tissue, hair, and blood Read More...
Web Page
Total end-to-end system for single-cell research [embed]https://youtu.be/vMzhSzg1rUw[/embed] The BD Rhapsody Single-Cell Analysis system empowers and streamlines your research with a complete system of tools, including reagents and analysis software, Read More...
Web Page
The Staff Scientists/Clinicians (SSSC) Technical Enrichment Program (STEP) was established to provide SSSC’s an opportunity to compete for funding to gain comprehensive training in state-of-the-art techniques available through CCR Cores and Facilities. The Read More...
Frederick, MD
Core Facility
Molecular Cytogenetics Core Facility facilitates the assessment of structural and numerical genomic changes in pre-cancer and cancer research models. This core provides comprehensive support for the cytogenetic analysis of cells from human and research animal Read More...
Web Page
Supplemental Technology Award Review System (STARS) Overview STARS Request Form STARS System The Supplemental Technology Award Review System (STARS) is a web-based interface for submission and review of S&S supplement requests by CCR Read More...
Bethesda, MD
Core Facility
Trans NIH Facility
The Department of Laboratory Medicine provides state-of-the-art laboratory testing in support of Clinical Center patient care and will serve as a center of excellence in research and training in laboratory medicine, particularly in areas which Read More...
Bethesda, MD
Trans NIH Facility
The Neurorehabilitation and Biomechanics Research Section (also referred to as the NAB LAB) is a multidisciplinary group of highly qualified scientists, clinical and technical staff, and trainees with diverse backgrounds including medical, physical therapy, neuroscience Read More...
Web Page
What is Visium FFPE v2 with CytAssist? Visium FFPE v2 is sequencing-based spatial profiling technology developed by 10x Genomics. This assay can take mouse or human tissue sections on normal glass slides as input and Read More...
Web Page
What is Xenium? Xenium is a high-resolution, imaging-based in situ spatial profiling technology from 10x Genomics that allows for simultaneous expression analysis of RNA targets (currently in range of 100’s) within the same tissue section. Read More...
Web Page
CREx News & Updates August 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGHLIGHTS Learn more about services from the NHLBI Read More...
Web Page
The Antibody Engineering Program (AEP) is part of the Center for Cancer Research (CCR) at the National Cancer Institute (NCI). The program focuses on generating therapeutic antibodies by phage display technology, including human antibodies and Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New NIH Resource Spotlight The NIH Lab Managers Working Group have developed a new NIH-wide database of cold Read More...
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CREx News & Updates July 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Click below to learn how easy it is to navigate the CREx platform. These short videos will Read More...
Web Page
CREx News & Updates October 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGLIGHTS Learn more about services from the CPTR Read More...
Web Page
CREx News & Updates April 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Click below to learn how easy it is to navigate the CREx platform. These short videos will Read More...
Bethesda, Maryland
Core Facility
Repositories
The AgingResearchBiobank was officially launched in January 2019 with a mission to provide a state-of-the-art inventory system for the storage, maintenance, and distribution of de-identified biospecimens and associated phenotypic, clinical, and imaging data from numerous NIA-funded Read More...
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The OSTR offers cutting-edge technology platforms to the CCR scientific community through centralized facilities. The videos accessed through this page are designed to introduce the various scientific methodologies OSTR makes available through the cores on Read More...
Rockville, MD
Trans NIH Facility
The Chemistry and Synthesis Center (CSC) of the National Heart, Lung, and Blood Institute (NHLBI) provides IRP scientists with targeted imaging probes and chemical tools that help accelerate cell-based assays, in vivo imaging studies, and Read More...
Web Page
Bioinformatics
Listed below are the video recordings of past BTEP events (classes, seminars, workshops). Videos are hosted on various servers and may play slightly differently. Some videos may be downloaded for local viewing. Recorded Videos of Read More...
Web Page
Bioinformatics
Lesson 11: Merging FASTQ quality reports and data cleanup Before getting started, remember to be signed on to the DNAnexus GOLD environment. Lesson 10 Review In the previous lesson, we learned about the structure of the FASTQ Read More...