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Bioinformatics
04/18/2023 - Efforts are underway to characterize cancer cell lines and identify their genetic and pharmacological vulnerabilities, but integration is essential for their interpretation. To empower researchers, to utilize the growing knowledge from these hundreds of Read More...
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Bioinformatics
03/19/2025 - Please note: Registration is required to get the Meeting Link for this event. Please pre-register. The Human Tumor Atlas Network (HTAN) is a National Cancer Institute (NCI)-funded initiative to construct 3-dimensional atlases of Read More...
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Bioinformatics
04/09/2025 - Game Changers in Computational Drug Discovery
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Bioinformatics
08/06/2024 - This webinar will focus on the data discovery and sharing infrastructure available for librarians and researchers. Demonstrating how technologies like repositories, data catalogs, and standards work together, this webinar will provide needed background on Read More...
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Bioinformatics
03/23/2023 - Learn how scientists are using ddPCR technology for absolute quantification of copy number variation, pathogen detection, detection of rare mutations, genome editing, and NGS data validation. We will go over ddPCR basics, and workflow Read More...
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Bioinformatics
11/30/2022 - This lecture will present an overview of various open-source databases and servers available that support pharmacogenomics research and drug discovery. Specifically, this lecture will focus on integrated-omics and data-driven approaches for novel drug discovery, Read More...
Bethesda, Maryland
Collaborative
Radiation Oncology Branch is part of CCR. Bioinformatics core is a collaborative resource to support ROB branch and provide service to ROB investigators from NCI and other Institutes access to new technologies, bioinformatics, statistical analysis Read More...
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Back Services: Biophysics Facility offers Octet as an open-access instrument. First-time users must complete a short training session before gaining access to the instrument reservation calendar. Training includes a full analysis of a Read More...
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Bioinformatics
09/25/2024 - Please join us on Wednesday, September 25, 2024, where Gina Kuffel, B.S., and Steph Singleton, M.S., will demo the newly launched Clinical and Translational Data Commons (CTDC). As the newest addition to NCI's Read More...
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Bioinformatics
10/03/2023 - Multiplexed antibody-based imaging enables the detailed characterization of molecular and cellular organization in tissues. Significant advances in the field now allow high-parameter data collection (60+ targets); however, considerable expertise and capital are needed to validate Read More...
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Bioinformatics
05/07/2025 - Join Dr. Eytan Ruppin, NCI investigator in the Center for Cancer Research, as he discusses Path2Space, a new and unpublished deep learning approach that predicts spatial gene expression directly from histopathology slides. Spatial Read More...
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Bioinformatics
03/21/2024 - Context-aware AI implemented to facilitate data discovery and harmonization has significantly accelerated some of the common bottlenecks in the collaborative research process. Pilot work has shows major time and cost savings compared to current Read More...
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Bioinformatics
10/13/2023 - Zhiyong Lu, Ph.D. will present AI in Medicine: Improving Access to Literature Data for Knowledge Discovery at the monthly Data Sharing and Reuse Seminar. The explosion of biomedical big data and Read More...
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Bioinformatics
Database for Annotation, Visualization and Integrated Discovery (DAVID) - practicing what we learned Learning objectives In this practice session, we will practice using DAVID. Practicing what we learned To help us apply what we learned Read More...
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Bioinformatics
Database for Annotation, Visualization and Integrated Discovery (DAVID) - an overview Before getting started, remember to be signed on to the DNAnexus GOLD environment. Lesson 17 review In the previous class, we got an overview of Read More...
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Bioinformatics
07/27/2023 - This new webinar will be covering and discussing the host responses to vaccines with invited speakers Dr. Oliver He and Dr. Guanming Wu. During the hour long webinar, Vaccine Induced Gene Expression Analysis Tool ( Read More...
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Bioinformatics
06/28/2023 - To register to attend, you must log in or create a free account. Do you want to better your communication on data science technologies and analyses with cancer immunotherapy researchers? If so, Read More...
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Bioinformatics
01/25/2023 - Please join us on Jan. 25 when Gemma Turon, Ph.D., and Miquel Duran-Frigola, Ph.D., from the Ersilia Open Source Initiative will present “Ersilia: A Hub of Open-Source AI/ML Models for Drug Discovery Read More...
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October 6, 2022 crex.nih.gov CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight NIH Center For Human Immunology, Inflammation, And Autoimmunity (CHI) CHI is a Read More...
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Bioinformatics
07/23/2025 - Harne ing the Power of Tran criptomic for cientific Di covery
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Bioinformatics
02/01/2024 - Please plan to attend this seminar on Zoom tomorrow. The meeting is sponsored by the NIH Virology Interest Group, but Dr. Parker is using some exciting tools to examine gene expression at the subcellular Read More...
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Bioinformatics
Database for Annotation, Visualization and Integrated Discovery (DAVID) - an overview Lesson 17 review In the previous class, we got an overview of functional and pathway analysis, which help to put RNA sequencing results into biological Read More...
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Bioinformatics
Before getting started, remember to be signed on to the DNAnexus GOLD environment.
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Bioinformatics
05/04/2023 - The National Cancer Insitute (NCI) Cancer Research Data Commons (CRDC) includes petabytes of genomic, proteomic, imaging and other data that can be immediately accessed and analyzed by approved users in a secure cloud environment. Read More...
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Bioinformatics
03/08/2023 - In this Center for Biomedical Informatics and Information Technology (CBIIT) sponsored seminar, Dr. Spyridon Bakas, professor at the University of Pennsylvania's Perelman School of Medicine, will present "Federated Learning Enabling Big Data Read More...
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Bioinformatics
10/14/2022 - The call for better data and evidence for decision-making has become very real as evidenced by the Federal Data Strategy, as well as the passage of both the Foundations of Evidence-based Policymaking Act (Evidence Read More...
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Bioinformatics
10/25/2022 - Speaker: Jill S. Barnholtz-Sloan, Ph.D. Associate Director Informatics and Data Science at the Center for Biomedical Informatics and Information Technology Senior Investigator Trans-Divisional Research Program, Division of Cancer Epidemiology and Genetics, NCI Dr. Read More...
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Bioinformatics
01/23/2024 - Looking for data sharing platforms to enhance your research and advance communal knowledge of childhood cancers? Join the first NCI Childhood Cancer Data Initiative (CCDI) webinar of the new year! Read More...
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Bioinformatics
We are using the datasets below in the Qiagen IPA course. Human Brain Reference (HBR) and Univeral Human Reference (UHR) dataset Using this for the one hour lecture (from 1 - 2 pm) Find more information about Read More...
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Bioinformatics
The genes that exhibit higher expression in the tumor tissue (ie. log2 fold change ≥ 1 and false discovery rate ≤ 0.05) have been subsetted into the file hcc1395_deg_chr22_up_genes.txt .
Bethesda, MD
Repositories
Trans NIH Facility
The NCI Genomic Data Commons (GDC) was established by the NCI Center for Cancer Genomics (CCG) to support the receipt, harmonization, distribution, and analysis of genomic and clinical data from cancer research programs. The GDC Read More...
Frederick, MD
Collaborative
The Antibody Characterization Laboratory (ACL) is the laboratory responsible for the development of well-characterized monoclonal antibody reagents. The NCI’s Office of Cancer Clinical Proteomics Research funds ACL as a resource to the entire cancer Read More...
Charlottesville, VA
Repositories
Trans NIH Facility
The Mid-Atlantic CHTN is one of six participating divisions of the Cooperative Human Tissue Network (CHTN) and is based in the Pathology Department at the University of Virginia. While primarily a resource for cancer researchers, Read More...
Frederick, MD
Collaborative
The Molecular Targets Program (MTP) is an organizational entity within the Center for Cancer Research (CCR) at NCI. The MTP provides the focus and infrastructure to enable CCR tenured and tenure-track Principal Investigators to initiate Read More...
Frederick, MD
Collaborative
The NMR Facility for Biological Research operates six NMR spectrometers with proton resonance frequencies from 850 to 500 MHz. Three of the highest field spectrometers (850, 700, 600) are equipped with higher sensitivity cryoprobes optimized for high-resolution multi-dimensional and relaxation Read More...
Bethesda, MD
Collaborative
The Pan-Microbial Serology Facility (PMSF) is part of the Center for Cancer Research (CCR) at the National Cancer Institute (NCI). The PMSF focuses on determining individualized pan-microbial immune profiles associated with human diseases including immunological Read More...
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Bioinformatics
06/06/2025 - The la t decade ha demon trated the power of genomic to unravel the etiology of complex trait and di ea e . The va t majority of genomic tudie have been ba ed on Read More...
Web Page
Bioinformatics
04/03/2025 - DAVID (the Database for Annotation, Visualization and Integrated Discovery) provides a comprehensive set of functional annotation tools for investigators to understand the biological meaning behind large lists of genes acquired from high-throughput assays such Read More...
Web Page
Bioinformatics
03/24/2025 - AI Club is a weekly meeting that explores various topics relating to AI and deep learning in biomedical sciences, typically in a seminar, workshop, or journal club format. AI Club is intended to be Read More...
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Bioinformatics
01/29/2025 - Join Dr. Douglas Flora, executive medical director of Oncology Services at St. Elizabeth Healthcare, to explore how artificial intelligence (AI) is revolutionizing cancer care through oncology. This event will cover: key AI terminology,& Read More...
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Bioinformatics
05/02/2024 - The explosion of biomedical big data and information in the past decade or so has created new opportunities for discoveries to improve the treatment and prevention of human diseases. As such, the field of Read More...
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Bioinformatics
04/23/2024 - Join Dr. Kai Tan of the Children’s Hospital of Philadelphia as he discusses his cutting-edge technology, CytoCommunity, for the supervised and unsupervised discovery of tissue cellular neighborhoods. CytoCommunity offers a powerful Read More...
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Bioinformatics
03/27/2024 - DAVID (the Database for Annotation, Visualization and Integrated Discovery) provides a comprehensive set of functional annotation tools for investigators to understand the biological meaning behind large lists of genes acquired from high-throughput assays such Read More...
Web Page
Bioinformatics
01/16/2024 - To register to attend, you must log in or create a free SITC Cancer Immunotherapy CONNECT account. It’s your last chance to register and learn about the cutting edge of computational immuno-oncology through Read More...
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Bioinformatics
10/05/2023 - Dr. Hoifung Poon is the General Manager at Health Futures of Microsoft Research and an affiliated professor at University of Washington Medical School. He leads biomedical AI research and incubation, with the overarching goal Read More...
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Bioinformatics
To complement this course, we have created a Biostars module on Biowulf. The following programs have been included in that module: Apps/Dependencies: bbtools bcftools bedtools bio bioawk blastn bowtie2 bwa cd-hit csvkit csvtk cutadapt Read More...
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Bioinformatics
Biostars Software Description To complement this course, we have created a Biostars module on Biowulf. The following programs have been included in that module: Apps/Dependencies: bbtools bcftools bedtools bio bioawk blastn bowtie2 bwa cd-hit Read More...
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Bioinformatics
This lesson will provide an overview of Database for Annotation, Visualization and Integrated Discovery (DAVID) . We will Provide some background on DAVID, including what it does statistical methods that it uses some expected outputs data Read More...
Web Page
Bioinformatics
This lesson will provide an overview of the Database for Annotation, Visualization and Integrated Discovery (DAVID) . We will Provide some background on DAVID, including what it does statistical methods that it uses some expected outputs Read More...
Web Page
Bioinformatics
Creates a local library of R packages copying what you used from your project. The primary functions and workflow is as follows: renv::init() initialize the project to be used with renv and creates a Read More...
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Bioinformatics
06/26/2023 - In this webinar, University of Chicago’s Dr. Bill Wysocki will demonstrate the NCI Genomic Data Commons’ (GDC’s) Binary Alignment Map (BAM) slicing feature. If you use Read More...
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Bioinformatics
06/23/2023 - Please join us for the launch of the NIGMS Sandbox, a cloud-based learning platform that contains 12 modules developed by NIGMS-supported investigators and Google Cloud engineers. Each module is delivered through an interactive step-by-step tutorial, Read More...
Web Page
Bioinformatics
10/20/2022 - An overview of the geospatial tools that are useful for characterizing areas of the country in terms of cancer incidence, mortality, screening frequency, risk factors, socio-demographic and environmental variables relevant to cancer. The presentation Read More...
Frederick, MD
Core Facility
The introduction of DNA sequencing instruments capable of producing millions of DNA sequence reads in a single run has profoundly altered the landscape of genetics and cancer biology. Complex questions can now be answered at Read More...
Frederick, MD
Collaborative
The Chemical Synthesis Group is a component of the Chemical Biology Laboratory. This facility provides synthetic chemistry resources and expertise to the NCI Intramural community. The facility’s capabilities include: Providing expertise, consultation, and experience Read More...
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CREx News & Updates January 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight NCI ANTIBODY CHARACTERIZATION LABORATORY (ACL) The ACL specializes in rigorously validating antibodies for signaling and Read More...
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September 8, 2022 crex.nih.gov CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight Trans-NIH Intramural Sequencing Center (NISC) NISC is a multi-disciplinary genomics facility that Read More...
Frederick, MD
Core Facility
The research conducted within the Synthetic Biologics Core (SBC) Facility has a dual role: Generate chemical biology tools and drug candidates for molecular targets identified by NCI research groups, Develop novel effective methods and tools Read More...
Web Page
Home About the Biophysics Core Biophysics Core Services [tabby title="Instrumentation"] NHLBI Biophysics Core The Biophysics Core Facility: Overview Core Facilities provide scientific resources, cutting-edge technologies and novel approaches to support DIR scientists. Availability of Read More...
Bethesda, MD
Core Facility
The CCR Genomics Core is located in Building 41 on the NIH Bethesda campus. The primary goal of the Core is to provide investigators from CCR/NCI and other NIH Institutes access to genomic technologies and Read More...
Bethesda, MD
Core Facility
The Biophysics Core’s mission is to provide support in the study of macromolecular interactions, dynamics, and stability by offering consultations, training, professional collaborations, and instrument access. General Services: Multi-technique molecular interaction studies, Kinetic and Read More...
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Biomarker Discovery with Morphological Context: Changing how tissue specimens are analyzed < https://youtu.be/mVhfZq8ppbc What is Digital Spatial Profiling? GeoMx Digital Spatial Profiler is a novel platform developed by NanoString. Digital Spatial Read More...
Frederick, MD
Collaborative
The Crystallization Facility provides an automated environment for setting up crystallization experiments in a high-throughput format, storing the resulting plates under controlled conditions, and monitoring the status of prepared droplets remotely. The Facility is in Read More...
Davis, CA
Trans NIH Facility
The Mouse Metabolic Phenotyping Center (MMPC)Live Program provides standardized, high quality, unique, and hard to find phenotyping services for mouse models of diabetes, obesity, and related metabolic disorders. Emerging as the next iteration of Read More...
Frederick, MD
Core Facility
The Clinical Support Laboratory offers processing, tracking, and testing of a broad range of clinical samples. Support can begin at the early stages of clinical trial development to aid in developing a comprehensive strategy for Read More...
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Back Services: Biophysics Facility offers MST as an open-access instrument. First-time users must complete a short training session before gaining access to the instrument reservation calendar. Training includes the KD determination of a Read More...
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CREx News & Updates July 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGHLIGHTS Learn more about services from the NHLBI Read More...
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OSTR provides CCR investigators with access to a variety of software licenses for genomic, proteomic, pathway analysis and data visualization tools. These software are funded by OSTR and made available at no cost to CCR Read More...
Frederick, Maryland
Core Facility
Repositories
The Biological Products Core provides the AIDS research community with high-quality purified preparations of various strains of Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV), economically prepared by leveraging the economy of scale. Materials Read More...
Bethesda, MD
Trans NIH Facility
The Science and Technology Research Infrastructure for Discovery, Experimentation, and Sustainability (STRIDES) Initiative The STRIDES Initiative aims to help NIH and its institutes, centers, and offices (ICOs) accelerate biomedical research by reducing barriers in utilizing Read More...
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Bioinformatics
07/25/2025 - Dr. Lee Lancashire is a data scientist with over 20 years of experience in machine learning and statistics, currently serving as Head of Data Science at Every Cure. He earned his PhD specializing in artificial Read More...
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Bioinformatics
07/15/2025 - Single-cell technologies enable the discovery of many novel cell phenotypes, but this growing body of knowledge remains fragmented across the scientific literature. Natural language processing (NLP) offers a promising approach to extract this information Read More...
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Bioinformatics
05/29/2025 - Prostate cancer exhibits significant intratumoral heterogeneity, driving a spectrum of phenotypes ranging from indolent disease to aggressive metastasis, challenging risk stratification and treatment. A key feature of this heterogeneity is clonal diversity, encompassing both Read More...
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Bioinformatics
05/16/2025 - This one-day in-person NIH AI Symposium will bring together researchers from a broad range of disciplines to share their AI-related research, with the goal of disseminating the newest AI research, providing an opportunity to Read More...
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Bioinformatics
04/17/2025 - Cardinal Bernardin Cancer Center Virtual Grand Rounds Interested in learning about various cancer indicators, approaches for data integration , and how to leverage data to drive scientific discovery? Then join NCI CBIIT’s Read More...
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Bioinformatics
01/08/2025 - This three hour online training will focus on getting started on using QIAGEN’s Ingenuity Pathway Analysis (IPA) . IPA enables you to quickly identify biological relationships, mechanisms, pathways, functions and Read More...
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Bioinformatics
11/12/2024 - Join us at the upcoming hybrid NIH BRAIN NeuroAI Workshop on November 12 and 13, with virtual access to in-person panels and discussions at the NIH Campus in Bethesda, MD. Artificial intelligence (AI) is reshaping technology Read More...
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Bioinformatics
Cancer research is a complex and data-intensive field. Cloud computing offers a powerful solution for researchers to store, analyze, and share large datasets efficiently. In this month’s topic spotlight, we will explore cloud resources Read More...
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Bioinformatics
Clinicians and bench scientists (a.k.a., wet lab researchers) are at the forefront of scientific achievement. However, most, if not all contemporary projects involve robust scientific analysis, where the tools of exploration aren’t Read More...
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Bioinformatics
07/19/2024 - The molecular mechanisms underlying many types of cancer involve aberrances in trans-acting factors and their binding to cis-regulatory elements to regulate gene expression. Techniques such as ChIP-seq, DNase-seq, and ATAC-seq are commonly used to Read More...
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Bioinformatics
07/18/2024 - Long read sequencing holds an advantage over short read sequencing in areas such as structural variant and transcript isoform discovery. This class will demonstrate long read analysis using Qiagen’s CLC Genomics Workbench, a Read More...
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Bioinformatics
07/12/2024 - We cordially invite you to attend the July Data Sharing and Reuse Seminar featuring Satra Ghosh, Ph.D. As the Director of the Open Data in Neuroscience Initiative and a Principal Research Scientist at Read More...
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Bioinformatics
07/11/2024 - Please join us for this special event featuring three speakers on the topic of Single-Cell Spatial Transcriptomics. George Zaki, Ph.D., Director, Applied Scientific Computing, BACS, The Frederick National Lab for Cancer Research, NCI/ Read More...
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Bioinformatics
06/20/2024 - Dr. Irizarry will share findings demonstrating limitations of current workflows that are popular in single cell RNA-Seq data analysis. Specifically, he will describe challenges and solutions to dimension reduction, cell-type classification, and statistical significance Read More...
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Bioinformatics
06/14/2024 - Data Sharing and Reuse Seminar Series Please join us for the June Data Sharing and Reuse Seminar where Micahel Schatz, Ph.D. will be presenting "BioDIGS: BioDiversity and Informatics for Genomics Scholars. This Read More...
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Bioinformatics
06/11/2024 - Large language models (LLMs) are artificial intelligence (AI) algorithms that employ deep learning and extensive data sets to create new content. LLMs offer many possible applications in the biomedical field, such as the development Read More...
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Bioinformatics
05/15/2024 - To register to attend, you must log in to your SITC Cancer Immunotherapy CONNECT account. Don’t have an account? Create a free one . Join Dr. Karchin of the Johns Read More...
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Bioinformatics
The Bioinformatics Training and Education Program is pleased to announce the Artificial Intelligence in Biomedical Research at NIH Seminar Series . Starting on Feb 29, these monthly events will be recorded and made available in the BTEP Read More...
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Bioinformatics
02/21/2024 - https://cap-lab.bio (link is external) https:// (link is external) qiime2.org (link is external) The QIIME platform, including QIIME 1 and QIIME 2 ( https://qiime2.org (link is external) ), has been extensively applied in microbiome Read More...
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Bioinformatics
Reproducibility in science means being able to generate the same experimental / analytical results with a high degree of reliability. This is necessary for research validation, scientific and public trust, innovation, and collaboration. Reproducibility is not Read More...
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Bioinformatics
Alpha diversity is within sample diversity. When exploring alpha diversity, we are interested in the distribution of microbes within a sample or metadata category. This distribution not only includes the number of different organisms (richness) Read More...
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Bioinformatics
Work through DNAnexus? Find a nice cancer data set for 16S and shotgun Divide into two workshops or courses? Course structure or workshop structure? Amplicon processing and analysis (5 week course) (4 weeks) 1. Talk by Greg Caparaso? 1. Read More...
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Bioinformatics
Microbiome Course Course Outline Work through DNAnexus? Find a nice cancer data set for 16S and shotgun Divide into two workshops or courses? Course structure or workshop structure? Amplicon processing and analysis (5 week course) (4 weeks) 1. Read More...
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Bioinformatics
09/20/2023 - This session of the BTEP Coding Club will focus on the tool rMATS for differential alternative splicing event detection from RNA-Seq data. This 1-hour demo will provide a detailed overview of rMATS including why Read More...
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Bioinformatics
09/11/2023 - We invite you to attend the Biobanking for Precision Medicine seminar series. The seminar series is brought to you by NCI’s Biorepositories and Biospecimen Research Branch (BBRB) and addresses current topics Read More...
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Bioinformatics
STAR 2-pass mode --sjdbGTFfile is the path to the file with annotated transcripts in standard GTF format, STAR extracts splice junctions from this file, improves accuracy of mapping. Using annotations is highly recommended whenever they Read More...
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Bioinformatics
Tasks to do at the Analysis Wizard : provide our input gene list (either copy paste or upload as a text file) specify gene identifier type (gene identifiers could be gene symbol, Ensembl IDs, Entrez IDs, Read More...
Web Page
Bioinformatics
Fisher Exact Test DAVID performs over representation analysis (ORA) at its core, which aims to find enriched molecular functions, pathways, or other annotations represented by the input gene list. In other words, many genes in Read More...
Web Page
Bioinformatics
Fisher Exact Test DAVID performs over representation analysis (ORA) at its core, which aims to find enriched molecular functions, pathways, or other annotations represented by the input gene list. In other words, many genes in Read More...
Web Page
Bioinformatics
06/29/2023 - Have you checked out NCI’s Childhood Cancer Data Initiative’s (CCDI’s) new online Hub ? It gives you instant access to a rapidly growing inventory Read More...
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Bioinformatics
06/29/2023 - Please join us for a special presentation about the Fred Hutchinson’s data journal to the cloud, including an innovative cloud platform (Cirro: https://cirro.bio/ ) to streamline data collection, Read More...
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Bioinformatics
06/13/2023 - Many cancer-related independent studies that employ bulk and single cell RNA-seq can be found in the Gene Expression Omnibus (GEO). While some studies provide aligned read files, these are processed non-uniformly. This shortcoming makes Read More...
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Bioinformatics
06/09/2023 - Dr. Nara Sobreira will present "PhenoDB, a phenotypic and genotypic data sharing tool" at the monthly Data Sharing and Reuse Seminar on June 9, 2023, at 12 p.m. EST. About the Seminar This seminar Read More...
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Bioinformatics
05/03/2023 - In this seminar, you’ll learn about the use of patient data combined from sources throughout the healthcare system. This type of patient data is called a longitudinal patient record (LPR), and Read More...
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Bioinformatics
04/06/2023 - Az imuth is a web application that uses an annotated reference dataset to automate the processing, analysis, and interpretation of a new single-cell RNA-seq experiment . Azimuth leverages a 'reference-based mapping' pipeline that inputs a Read More...
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Bioinformatics
04/03/2023 - Workshop Description: The application of AI to cancer research holds promise to accelerate new discoveries, enable early detection, improve diagnosis, and spur development of new therapies for cancer. Machine learning and other forms of Read More...
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Bioinformatics
03/10/2023 - Dr. Melissa Haendel and Dr. Jakob Seidlitz will present "2022 DataWorks! Grand Prize Winners: Innovations in Data Sharing and Reuse" at the monthly Data Sharing and Reuse Seminar on March 10, 2023 at 12 p.m. Read More...
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Bioinformatics
02/23/2023 - In this session we will go over a visual, dynamic, and interactive way to work with OMICs data using public leukemia GEO gene expression data sets. We will approach the data with confirmatory and Read More...
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Bioinformatics
11/10/2022 - Join Google’s Marcos Novaes, Ph.D., as he presents on the design of large-scale solutions for high-performance computing, machine learning, and the internet of things using the Google Cloud Platform. Dr. Norvaes will Read More...
Web Page
Bioinformatics
11/01/2022 - Learn how to get started on using QIAGEN’s Ingenuity Pathway Analysis (IPA) to quickly identify biological relationships, mechanisms, pathways, functions and diseases most relevant to experimental datasets. IPA is cited in tens of Read More...
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Bioinformatics
10/19/2022 - Our bodies host millions of microorganisms, and our relationship with these tiny living companions is complex. While microbial communities support normal processes and defend against harmful pathogens, infections with some viruses and bacteria can Read More...
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September 8, 2022 crex.nih.gov CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Science & Technology Seminars and Training Events Upcoming Seminars and Educational Opportunities The following Read More...
Frederick, MD
Repositories
Trans NIH Facility
DTP’s Natural Products Repository is the world’s largest storehouse of natural products. It houses close to >200,000 extracts from samples of more than 70,000 plants and >20,000 marine organisms collected from more than 29 countries, plus extracts Read More...
Web Page
Mass Spectrometry Section of the Collaborative Protein Technology Resource (Bldg. 37) Core Capabilities: Identification of proteins in complexes, organelles, subcellular fractions, or fluids. Global relative protein quantitation. Quantitation by isotopic labeling of cells in culture (SILAC) Read More...
Bethesda, MD
Collaborative
Our operational objectives are to provide state-of-the-art OMICS technologies in support of the Genetics Branch (GB) investigators and collaborators. Research Services Wet Lab Single cell isolation from fresh, frozen, and FFPE tissue, DNA/RNA extractions Read More...
Frederick, MD
Collaborative
The Biopharmaceutical Development Program (BDP) provides resources for the development of investigational biological agents. The BDP supports feasibility through development and Phase I/II cGMP manufacturing plus regulatory documentation.The BDP was established in 1993. We Read More...
Bethesda, MD
Core Facility
The Genomics and Pharmacology Facility is part of the NCI's Center for Cancer Research (CCR), within the Developmental Therapeutics Branch. Its mission is to manage and assess molecular interaction data obtained through multiple platforms, increase Read More...
Frederick, MD
Collaborative
The Medicinal Chemistry Accelerator (MCA) is a collaborative CCR resource that supports investigators in developing small molecule inhibitors for anticancer drug candidates. While CCR and NCATS have infrastructure to identify initial “hits” through high-throughput screening, Read More...
Web Page
Back Services: Biophysics Facility offers ZetaView as an open-access instrument. First-time users must complete a short training session before using it for the first time. Training includes instrument calibration and size analysis of a standard Read More...
Rockville, MD
Collaborative
Repositories
Proteomic Data Common (PDC) represents the NCI’s largest public repository of proteogenomic comprehensive tumor datasets, essentially a Proteogenomic Cancer Atlas. It was developed to advance our understanding of how proteins help shape the risk, Read More...
Bethesda, MD
Collaborative
The Antibody Engineering Program (AEP) is located at the Laboratory of Molecular Biology, which is part of the Center for Cancer Research (CCR), an intramural program at the National Cancer Institute (NCI). AEP focuses on Read More...
Rockville, MD
Collaborative
Repositories
The NCI Cloud Resources are components of the NCI Cancer Research Data Commons (CRDC) that bring data and computational power together to enable cancer research and discovery. These cloud-based platforms eliminate the need for researchers Read More...
Web Page
What is Visium FFPE v2 with CytAssist? Visium FFPE v2 is sequencing-based spatial profiling technology developed by 10x Genomics. This assay can take mouse or human tissue sections on normal glass slides as input and Read More...
Frederick, MD
Core Facility
The FNLCR Molecular Histopathology Laboratory (MHL) provides comprehensive veterinary pathology support for animal health monitoring, biomarker discovery and validation, drug development, genomics, and proteomics on a cost recovered basis. The MHL is organized into multiple Read More...
Bethesda, MD
Collaborative
Repositories
The National Cancer Institute (NCI) is developing a national repository of Patient-Derived Models (PDMs) comprised of patient-derived xenografts (PDXs), patient-derived organoids (PDOrg), and in vitro patient-derived tumor cell cultures (PDCs) and cancer-associated fibroblasts (CAFs). These Read More...
Web Page
CREx News & Updates August 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight NCATS Functional Genomics Laboratory (FGL) FGL is designed to help NIH Investigators use the latest Read More...
Bethesda, MD
Trans NIH Facility
The NIH Center for Human Immunology, Inflammation, and Autoimmunity (CHI) is a trans-NIH resource whose mission is to provide a collaborative hub of advanced translational immunology for NIH clinical and pre-clinical studies. This uniquely structured Read More...
Web Page
CREx News & Updates November 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight FACILITY HIGLIGHTS Learn more about services from the NINDS Quantitative Magnetic Resonance Imaging Core. NINDS Read More...
Bethesda, MD
Collaborative
The Spatial Imaging Technology Resource (formerly the Nanoscale Protein Analysis Section of the Collaborative Protein Technology Resource or CPTR) provides expertise and service in state-of-the-art protein analysis technologies to advance CCR research in basic discovery Read More...
Rockville, MD
Trans NIH Facility
The Chemistry and Synthesis Center (CSC) of the National Heart, Lung, and Blood Institute (NHLBI) provides IRP scientists with targeted imaging probes and chemical tools that help accelerate cell-based assays, in vivo imaging studies, and Read More...
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Bioinformatics
Listed below are the video recordings of past BTEP events (classes, seminars, workshops). Videos are hosted on various servers and may play slightly differently. Some videos may be downloaded for local viewing. Recorded Videos of Read More...
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Bioinformatics
The FindAllMarkers function is particularly useful in identifying the differentially expressed genes that distinguish several groups, such as seen here in the clusters. What makes this unique is that none of the identities are initially Read More...
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Bioinformatics
1. Introduction and Learning Objectives This tutorial has been designed to demonstrate common secondary analysis steps in a scRNA-Seq workflow. We will start with a merged Seurat Object with multiple data layers representing multiple samples that Read More...
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Bioinformatics
Objectives To explore Bioconductor, a repository for R packages related to biological data analysis. To learn about options for report generation with R: RMarkdown and Quarto. Introducing Bioconductor Bioconductor is both an open source project Read More...
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Bioinformatics
Lesson 5: Microbial diversity, alpha rarefaction, alpha diversity Learning Objectives Understand the difference between alpha and beta diversity Introduce several alpha diversity metrics Understand what rarefaction is and why it is important Introduce the debate regarding Read More...
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Bioinformatics
NCI scientists have many choices available to them for bioinformatic analyses of Next Generation Sequencing (NGS) data. While some require expertise in programming, others provide a more user-friendly, point-and-click interface. These options include programs for Read More...
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Bioinformatics
Prior to differential expression analysis, we need to generate a design.csv file that contains the samples and their corresponding treatment conditions. Note that csv stands for comma separated value so the columns in these Read More...
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Bioinformatics
How to download data from the Sequence Read Archive (NCBI/SRA) to your account on NIH HPC Biowulf You will need: active, unlocked Biowulf account (hpc.nih.gov) active Globus account for transferring files OR Read More...
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Bioinformatics
Lesson 15: Finding differentially expressed genes Before getting started, remember to be signed on to the DNAnexus GOLD environment. Lesson 14 review In the previous lesson, we learned to visualize RNA sequencing alignment results in the Integrative Read More...
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Bioinformatics
Lesson 3: R Project Management and renv Learning objectives Discuss the importance of reproducibility Learn ways to make R analyses more reproducible Learn how to set up and organize an R project Learn how to use Read More...
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Bioinformatics
We now know enough to put our new skills to use to make a volcano plot from RNASeq data. A volcano plot is a type of scatterplot that shows statistical significance (P value) versus magnitude Read More...
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Bioinformatics
Scatter plots and plot customization Objectives Learn to customize your ggplot with labels, axes, text annotations, and themes. Learn how to make and modify scatter plots to make fairly different overall plot representations. Load a Read More...
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Bioinformatics
The identification of cell types in single cell genomics data (cell type annotation) can provide new insights into cellular identities, heterogeneity, and functional roles. Cell type annotation is challenging Read More...