Web Page
Bioinformatics
09/12/2024 - Telomere to telomere (T2T) genome assemblies represent a paradigm shift in comparative genomics, offering insights into chromosome structure, evolution, and function at the highest resolution. Dr. O'Neill's lab has made recent Read More...
Web Page
Bioinformatics
Hands on Programming with R R for Data Science (R4DS) BTEP R Introductory Series Base R cheat sheet RStudio cheat sheet
Web Page
Bioinformatics
The best way to sign onto Biowulf from a Mac is to use the built-in terminal (Figure 4). Use the Spot Light search at the Mac menu bar to search for the Terminal application. Click on Read More...
Web Page
Bioinformatics
The best way to sign onto Biowulf from a Mac is to use the built-in terminal (Figure 4). Use the Spot Light search at the Mac menu bar to search for the Terminal application. Click on Read More...
Web Page
Back Services: Biophysics Facility offers DLS as an open-access instrument. First-time users must complete a short training session before gaining access to the instrument reservation calendar. Training includes DLS analysis of small- and large-molecular size Read More...
Web Page
Back Services: We offer a limited sample processing service using standard SEC-MALS and FFF protocols. This service is intended for the occasional users of this system. Researchers who expect to use this instrument Read More...
Web Page
Bioinformatics
For Further Reading Getting started with R Hands on Programming with R R for Data Science (R4DS) BTEP R Introductory Series Base R cheat sheet RStudio cheat sheet General help with ggplot2 ggplot2 cheatsheet Read More...
Bethesda, MD
Trans NIH Facility
The facilities at AIM are available for use by the entire NIH intramural research community. While we welcome users with any size imaging project, AIM specializes in large, yearlong (or longer), collaborative research efforts with Read More...
Bethesda, MD
Core Facility
The core provides access to several different state-of-the-art 3D microscopes as well as computers to visualize and process image data. The facility houses equipment for 2D or 3D imaging of fixed and living specimens. High Read More...
Web Page
Confocal
ZEISS Elyra 7 with Lattice SIM² Type: Wide-field structured illumination microscope Capabilities: Super resolution 2D and 3D imaging of live or fixed cells Apotome SIM: 170 nm lateral, 450 nm axial Apotome SIM2: 140 nm lateral, 300 nm axial Lattice Read More...
Web Page
Bioinformatics
05/29/2025 - Prostate cancer exhibits significant intratumoral heterogeneity, driving a spectrum of phenotypes ranging from indolent disease to aggressive metastasis, challenging risk stratification and treatment. A key feature of this heterogeneity is clonal diversity, encompassing both Read More...
Web Page
Bioinformatics
BashScripting_LinuxCommands from the NIH HPC team Fosswire linux reference sheet
Web Page
Bioinformatics
Base R cheat sheet Other cheat sheets can be here . There is also a nice review here .
Web Page
Bioinformatics
BashScripting_LinuxCommands from the NIH HPC team Fosswire linux reference sheet
Web Page
Bioinformatics
Include a cheat sheet and flow diagram of how the versioning process works with Git. Git detached HEAD
Frederick, MD
Core Facility
OMAL focuses its research and development activities to quantitatively understand the molecular basis of three-dimensional (3D) cell organization, motility, invasion, and differentiation using fixed samples and live, 3D tissue culture models (i.e., translational models). Read More...
Bethesda, MARYLAND
Core Facility
The CCR Microscopy Core provides NCI investigators access to state-of-the-art imaging tools and techniques, including light sheet fluorescence, high-resolution confocal, multi-photon, and super-resolution microscopy. The mission of the CCR Microscopy Core Facility is to support Read More...
Web Page
Bioinformatics
07/08/2025 - Thi pre entation de cribe the ba ic mechanic of con tructing a deci ion tree and interpreting the re ult . Deci ion tree will be u ed to determine factor a ociated with 2 Read More...
Web Page
Bioinformatics
Base R cheat sheet Other cheat sheets can be found here . There is also a nice review here . There are a ton of free tutorials. There are at least 230 Git repositories that focus on R Read More...
Web Page
Bioinformatics
[et_pb_section bb_built="1" _builder_version="3.0.84" custom_margin="0px|||" custom_padding="0px|||"][et_pb_row _builder_version="3.0.47" background_size="initial" background_position=& Read More...
Web Page
Bioinformatics
BashScripting_LinuxCommands from the NIH HPC team Fosswire linux reference sheet
Web Page
Bioinformatics
BashScripting_LinuxCommands from the NIH HPC team Fosswire linux reference sheet
Web Page
Bioinformatics
Each participant will be assigned a student account. See here for student account assignment. Please use this account throughout this course. Enter NIH credentials to see the student account assignment sheet after clicking the link.
Web Page
Bioinformatics
Each participant will be assigned a student account. See here for student account assignment. Please use this account throughout this course. Enter NIH credentials to see the student account assignment sheet after clicking the link.
Web Page
Bioinformatics
Click on the "Add project" tab to create a new analysis project. Import data: Partek Flow handles many data types but for this class, we will select bulk and then RNA. Partek Flow Read More...
Bethesda, MD
Core Facility
The LCBG Microscopy Core offers imaging technologies and training. The Core has established instrumentation for for 2D and 3D imaging of both fixed and living specimens.
Bethesda, MD
Core Facility
LCMB Microscopy Core offers live cell imaging technologies as well as super-resolution, fluorescence lifetime and confocal imaging systems for immunofluorescence. Our confocal instruments are a Leica SP8 laser scanning confocal microscope and a Nikon spinning Read More...
Frederick, MD
Core Facility
Clinical Support Laboratory – Cellular Immunology offers a spectrum of bioassays to assess cellular responses to antigens and mitogens including ELISPOT, cytotoxicity assays, and proliferation assays. Established Technologies Elispot Assays, Dual or Triple Color Fluorospot Assays, Read More...
Web Page
Bioinformatics
03/20/2024 - Our series of talks continues with two 20-minute presentations. There will be light refreshments (coffee and donuts) provided, so please consider attending in person! We encourage attendees to stay and chat with Read More...
Web Page
Bioinformatics
01/10/2024 - Our series of talks continues next month with two 20-minute presentations focused on single cell genomics studies in the model organism zebrafish. There will be light refreshments and we encourage attendees to Read More...
Web Page
Bioinformatics
Import data from the sheet "iris_data_long" from the excel workbook (file_path = "./data/iris_data.xlsx"). Make sure the column names are unique and do not contain spaces. Save Read More...
Web Page
Bioinformatics
Excel files are the primary means by which many people save spreadsheet data. .xls or .xlsx files store workbooks composed of one or more spreadsheets. Importing excel files requires the R package readxl . While this Read More...
Web Page
Bioinformatics
10/04/2023 - Our series of talks continues this month with two 20-minute presentations. There will be light refreshments and we encourage attendees to stay and chat with colleagues after the presentations. & Read More...
Web Page
Bioinformatics
10/25/2022 - Speaker: Jill S. Barnholtz-Sloan, Ph.D. Associate Director Informatics and Data Science at the Center for Biomedical Informatics and Information Technology Senior Investigator Trans-Divisional Research Program, Division of Cancer Epidemiology and Genetics, NCI Dr. Read More...
Web Page
Bioinformatics
01/07/2022 - Environmental exposures such as smoking are widely recognized risk factors in the emergence of lung diseases including lung cancer and acute respiratory distress syndrome (ARDS). However, the strength of environmental exposures is difficult to Read More...
Web Page
Bioinformatics
02/17/2021 - Speaker is Dr. Michal Linial from the Hebrew University of Jerusalem, Israel. Abstract: Incredible progress has also been made in the field of cancer genetics with the sequencing and molecular profiling of tens of Read More...
Web Page
Bioinformatics
Sign onto Biowulf using the assigned student account. Remember, Windows users will need to open the Command Prompt and Mac users will need to open the Terminal. Also remember to connect to the NIH network Read More...
Web Page
Bioinformatics
Sign onto Biowulf using the assigned student account. Remember, Windows users will need to open the Command Prompt and Mac users will need to open the Terminal. Also remember to connect to the NIH network Read More...
Web Page
Bioinformatics
The data used in this practice exercise can be found here. Q1. Import data from the sheet "iris_data_long" from the excel workbook (file_path = "./data/iris_data.xlsx"). Make Read More...
Web Page
Bioinformatics
Sign onto Biowulf using the assigned student account. Remember, Windows users will need to open the Command Prompt and Mac users will need to open the Terminal. Also remember to connect to the NIH network Read More...
Web Page
Bioinformatics
Sign onto Biowulf using the assigned student account. Remember, Windows users will need to open the Command Prompt and Mac users will need to open the Terminal. Also remember to connect to the NIH network Read More...
Web Page
Bioinformatics
Sign onto Biowulf using the assigned student account. Remember, Windows users will need to open the Command Prompt and Mac users will need to open the Terminal. Also remember to connect to the NIH network Read More...
Web Page
Bioinformatics
Sign onto Biowulf using the assigned student account. Remember, Windows users will need to open the Command Prompt and Mac users will need to open the Terminal. Also remember to connect to the NIH network Read More...
Bethesda, MD
Trans NIH Facility
NIH Intramural CryoEM Consortium (NICE) serves intramural investigators in all NIH IC’s. NICE provides access to state-of-the-art Titan Krios cryo-electron microscopes for atomic-resolution structure determination of protein, macromolecular complexes, membrane receptors, cellular organelles, and Read More...
Bethesda, MD
Collaborative
As a multi-user facility, the different instruments provide a wide range of imaging modes for EIB scientists, from standard immunohistochemistry, through brightfield and wide-field epifluorescence imaging, to highly complex live cell confocal microscopy and super-resolution Read More...
Frederick, MD
Collaborative
The Crystallization Facility provides an automated environment for setting up crystallization experiments in a high-throughput format, storing the resulting plates under controlled conditions, and monitoring the status of prepared droplets remotely. The Facility is in Read More...
Web Page
CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Intramural CryoEM (NICE) Consortium NICE provides NCI, NIAID, NIEHS, NICHD, NIDCR, NEI, and NIA investigators with Read More...
Web Page
CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Extramural Common Fund Resources Metabolomics Workbench Developed by the NIH Metabolomics Common Fund's National Metabolomics Data Repository ( Read More...
Web Page
Electron Microscopy Laboratory (EML) The EML offers investigators access to unique expertise and EM technologies that allow our partners to explore new avenues of research to enhance the knowledge of biological systems. To assist our Read More...
Bethesda, MD
Collaborative
The NCI High-Throughput Imaging Facility (HiTIF) works in a collaborative fashion with NCI/NIH Investigators by providing them with the necessary expertise, instrumentation, and software to develop and execute advanced High-Throughput Imaging (HTI) assays. These Read More...
Poolesville, MD
Core Facility
Trans NIH Facility
The NIA Nonhuman Primate (NHP) Core Facility maintains a colony of rhesus macaques at the National Institutes of Health Animal Center. Established in 2012, the Core's mission is to offer research services supporting multi-disciplinary translational aging Read More...
Web Page
Confocal
WIDE-FIELD MICROSCOPY Nikon Ti 2000 wide-field microscope Capabilities: This microscope is suited for live cell imaging (4D) and fixed cells (3D) imaging. This microscope produces high quality wide-field images that may be improved by Read More...
Web Page
Confocal
2024 Date: Tuesday, October 15, 2024 Time and Location: 11 am EST, ZOOM (INVITATION BY LMIG LIST SERVER) Speaker: Dr. Diego Presman (U Buenos Aires) Title: “Insights on Glucocorticoid Receptor Activity Through Live Cell Imaging” Summary: Eucaryotic transcription factors ( Read More...
Web Page
Bioinformatics
Help Session Lesson 3 Loading data Import data from the sheet "iris_data_long" from the excel workbook (file_path = "./data/iris_data.xlsx"). Make sure the column names are unique and Read More...
Web Page
Bioinformatics
09/06/2023 - With the advancements in single cell and spatial profiling technologies and methods, some of us thought it would be helpful to re-establish a community of end users on campus. We invite those that are Read More...
Web Page
Bioinformatics
This page contains content taken directly from the Biostar Handbook by Istvan Albert. Activate the bioinformatics environment. conda activate bioinfo First let's make a place to store today's work. In your biostar_class Read More...
Web Page
Bioinformatics
Whether you are measuring mRNA expression, protein expression, DNA methylation, expressed miRNAs, protein binding to DNA or RNA, etc., you will likely end up with a list of genes or gene products from which you Read More...
Web Page
Bioinformatics
06/22/2022 - Cancer origination and progression is a complex process that can be viewed as a somatic evolutionary progression with clonal cellular expansion(s) driven by accumulation of survival-/evasion-beneficial genomic mutations, alongside constantly changing selective Read More...
Web Page
Bioinformatics
02/16/2022 - For our next CDSL webinar we will have a guest lecture by Dr. Leng Han from the Center for Epigenetics and Disease Prevention at Texas A&M University. Abstract: Despite advancements in Read More...
Web Page
Bioinformatics
Q1. Import data from the sheet "iris_data_long" from the excel workbook (file_path = "./data/iris_data.xlsx"). Make sure the column names are unique and do not contain spaces. Read More...
Web Page
Bioinformatics
Excel files are the primary means by which many people save spreadsheet data. .xls or .xlsx files store workbooks composed of one or more spreadsheets. Importing excel files requires the R package readxl. While this Read More...
Web Page
Bioinformatics
After data has been transferred to the NIH Partek Flow server, the next step is to import them into a project. Sign onto Partek Flow and hit the "New project" button click to Read More...
Web Page
Bioinformatics
Navigate to the GDC Data Portal at https://portal.gdc.cancer.gov/ To select your cases of interest, you can navigate to "Projects" or "Cohort Builder" Let's use breast cancer Read More...
Web Page
Bioinformatics
Load the data: library(readxl) TCR_fp<-file.path("..","data","S1_VLOOKUP","TCR_example", "4261-R1_filtered_contig_annotations.xlsx") df<-read_ Read More...
Web Page
[tabby title="Home"] About NICE-NIH Intramural CryoEM Consortium NIH Intramural CryoEM Consortium (NICE) serves intramural investigators in all NIH IC’s. NICE provides access to state-of-the-art Titan Krios cryo-electron microscopes for atomic-resolution structure determination of Read More...
Web Page
Back Services: Biophysics Facility offers MP as an open-access instrument. First-time users must complete a short training session before gaining access to the instrument training calendar. Training includes mass distribution analysis of a Read More...
Frederick, MD
Core Facility
The research conducted within the Synthetic Biologics Core (SBC) Facility has a dual role: Generate chemical biology tools and drug candidates for molecular targets identified by NCI research groups, Develop novel effective methods and tools Read More...
Web Page
Back Services: Biophysics Facility offers fluorometers as open-access instruments. First-time users must complete a short training session before gaining access to the instrument reservation calendar. Location: Building 50, room 3226 Description: Some substances reemit light after Read More...
Bethesda, MD
Core Facility
The Biophysics Core’s mission is to provide support in the study of macromolecular interactions, dynamics, and stability by offering consultations, training, professional collaborations, and instrument access. General Services: Multi-technique molecular interaction studies, Kinetic and Read More...
Web Page
Back Services: Biophysics Facility offers ZetaView as an open-access instrument. First-time users must complete a short training session before using it for the first time. Training includes instrument calibration and size analysis of a standard Read More...
Bethesda, MD
Collaborative
Our operational objectives are to provide state-of-the-art OMICS technologies in support of the Genetics Branch (GB) investigators and collaborators. Research Services Wet Lab Single cell isolation from fresh, frozen, and FFPE tissue, DNA/RNA extractions Read More...
Frederick, MD
Core Facility
The Biophysics Resource (BR) was established in January 2001. Our mission is to provide CCR investigators with access to both the latest instrumentation and expertise in characterizing the biophysical aspects of systems under structural investigation. The Read More...
Web Page
:root { --primary-action: rgb(0, 0, 0) !important; --primary-action: rgb(0, 0, 0) !important; } .container { width: 1440px; max-width: 100%; } #h2 { font-size: 2.2rem; margin-left: 20px; } /* Lazy Load Styles */ .card-image { display: block; min-height: 20rem; /* layout hack */ background: #fff center center no-repeat; background-size: cover; filter: blur(3 Read More...
Web Page
Back Services: We offer a limited sample processing service using standard SEC-MALS and FFF protocols. This service is intended for the occasional users of this system. Researchers who expect to use this instrument Read More...
Web Page
Many established and emerging technologies are available to CCR scientists. This technology-rich environment makes the CCR a unique place to conduct scientific research. Through the OSTR, the CCR continues to find Read More...
Rockville, MD
Core Facility
Trans NIH Facility
The Functional Genomics Laboratory (formerly, the RNAi Screening Facility) of the National Center for Advancing Translational Sciences (NCATS) assist investigators with all stages of project planning and execution, beginning with assay development through genome-wide siRNA Read More...
Bethesda, MD
Trans NIH Facility
The NIH Library is a biomedical research library, whose collection and services are available at no cost to NIH staff: Electronic Resources: Over 20,000 electronic journals, 190,000 eBooks, and 50 databases. , Training classes covering topics such as bioinformatics, Read More...
Web Page
Home About the Biophysics Core Biophysics Core Services [tabby title="Instrumentation"] NHLBI Biophysics Core The Biophysics Core Facility: Overview Core Facilities provide scientific resources, cutting-edge technologies and novel approaches to support DIR scientists. Availability of Read More...
Web Page
CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx User Survey The CREx Team is carrying out a CREx User Survey. We would greatly appreciate Read More...
Web Page
CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx User Survey The CREx Team is carrying out a CREx User Survey. If you haven’t Read More...
Bethesda, MD
Collaborative
The Spatial Imaging Technology Resource (formerly the Nanoscale Protein Analysis Section of the Collaborative Protein Technology Resource or CPTR) provides expertise and service in state-of-the-art protein analysis technologies to advance CCR research in basic discovery Read More...
Web Page
Back Services: Biophysics Facility offers Octet as an open-access instrument. First-time users must complete a short training session before gaining access to the instrument reservation calendar. Training includes a full analysis of a Read More...
Web Page
Back Services: Biophysics Facility offers MST as an open-access instrument. First-time users must complete a short training session before gaining access to the instrument reservation calendar. Training includes the KD determination of a Read More...
Web Page
Services: Biophysics Facility offers CD as an open-access instrument. First-time users must complete a short training session before gaining access to the instrument reservation calendar. Location: Building 50, room 3123 Description: CD spectroscopy measures the difference Read More...
Web Page
Back Services: Biophysics Facility offers CD as an open-access instrument. First-time users must complete a short training session before gaining access to the instrument reservation calendar. Location: Building 50, room 3123 Description: CD spectroscopy measures the Read More...
Frederick, MD
Collaborative
The Biopharmaceutical Development Program (BDP) provides resources for the development of investigational biological agents. The BDP supports feasibility through development and Phase I/II cGMP manufacturing plus regulatory documentation.The BDP was established in 1993. We Read More...
Rockville, MD
Trans NIH Facility
The Chemistry and Synthesis Center (CSC) of the National Heart, Lung, and Blood Institute (NHLBI) provides IRP scientists with targeted imaging probes and chemical tools that help accelerate cell-based assays, in vivo imaging studies, and Read More...
Frederick, MD
Collaborative
In order to meet increasing demands from both NIH intramural and extramural communities for access to a small angle X-ray scattering (SAXS) resource, the Center for Cancer Research (CCR) under the leadership of Drs. Jeffrey Read More...
Web Page
Confocal
Software Image Acquisition Commercial imaging systems of LRBGE Optical Microscopy Core are controlled by acquisition software specifically designed for the appropriate microscope, such as ZEN (Zeiss confocal microscopes), Nikon Elements (Nikon), Imspector (Abberior). Custom-built HILO Read More...
Web Page
Confocal
Contact the CCR Microscopy Core to discuss your experiment Thank you for your interest in using the CCR Microscopy Core. Please login to the Bookitlab with your NIH credentials and register Read More...
Web Page
Bioinformatics
Listed below are the video recordings of past BTEP events (classes, seminars, workshops). Videos are hosted on various servers and may play slightly differently. Some videos may be downloaded for local viewing. Recorded Videos of Read More...
Web Page
Bioinformatics
This lesson provides an introduction to R in the context of single cell RNA-Seq analysis with Seurat. Learning Objectives Learn about options for analyzing your scRNA-Seq data. Learn about resources for learning R programming. Learn Read More...
Web Page
Bioinformatics
Data import and reshape Objectives 1. Learn to import multiple data types 2. Data reshape with tidyr : pivot_longer() , pivot_wider() , separate() , and unite() Installing and loading packages So far we have only worked with objects that Read More...
Web Page
Bioinformatics
Lesson 1: Introduction to Biowulf, Unix, and R Learning Objectives Learn about why you may want to use R on Biowulf. Refresh Unix and R skills. This lesson will not be hands on. Why use R Read More...
Web Page
Bioinformatics
Learning Objectives Understand the components of an HPC system. How does this compare to your local desktop? Learn about Biowulf, the NIH HPC cluster. Learn about the command line interface and resources for learning. What Read More...