Search Results for: genetic monitoring

09/28/2021 - Attend this webinar to hear from Dr. Arul Chinnaiyan, molecular pathologist and physician scientist who leads a multi-disciplinary team of investigators at the Michigan Center for Translational Pathology. He and his team work to Read More...

01/29/2020 - NCI Shady Grove, 9609 Medical Center Drive, Room 2W032/034, and via Webinar Rachel Karchin, Ph.D., and Kym Pagel, Ph.D. Dr. Karchin and Dr. Pagel will present OpenCRAVAT, a new open source, scalable decision Read More...

09/22/2022 - The avalanche of easy-to-create genomics data has impacted almost all areas of medicine and science, from cancer patients and microbial diagnostics to molecular monitoring for astronauts in space. In this lecture, new discoveries from Read More...

04/18/2023 - Register by April 03, 2023. Using information gleaned from a person’s genome can assist clinicians in customizing their patient’s case management and increase the likelihood of a positive outcome. While NCBI has long had Read More...

12/14/2021 - Speaker: Alisa Goldstein, Ph.D. Senior Investigator NCI, Division of Cancer Epidemiology and Genetics, Clinical Genetics Branch Dr. Alisa Goldstein is a Senior Investigator in NIH’s Division of Cancer Epidemiology and Genetics (DCEG), Read More...

08/28/2020 - Speaker: Dr. Luke Gilbert is an Assistant Professor in the Department of Urology, the Helen Diller Family Comprehensive Cancer Center and the Innovative Genomics Institute at the University of California, San Francisco. Dr. Gilbert Read More...

2024 Date: Tuesday, October 15, 2024 Time and Location: 11 am EST, ZOOM (INVITATION BY LMIG LIST SERVER) Speaker: Dr. Diego Presman (U Buenos Aires) Title: “Insights on Glucocorticoid Receptor Activity Through Live Cell Imaging” Summary: Eucaryotic transcription factors ( Read More...

09/22/2022 - The avalanche of easy-to-create genomics data has impacted almost all areas of medicine and science, from cancer patients and microbial diagnostics to molecular monitoring for astronauts in space. In this lecture, new discoveries from Read More...

06/25/2025 - Dr. Cleary will pre ent their late t work developing Perturb-FI H, a method that capture the effect of genetic change within and between cell while pre erving the patial architecture of living y Read More...

05/01/2025 - In this talk, Dr. Stergachis will present data on using Fiber-seq and deaminase-assisted Fiber-seq (DAF-seq) to resolve the functional impact of both germline and somatic genetic variants, as well as to identify somatic epimutations Read More...

10/15/2024 - This one-hour online training will cover techniques on locating biomedical research articles, patents, NIH-funded research projects, genetic information, and print and electronic books related to animal models and model organisms. This training will also Read More...

06/09/2023 - Dr. Nara Sobreira will present "PhenoDB, a phenotypic and genotypic data sharing tool" at the monthly Data Sharing and Reuse Seminar on June 9, 2023, at 12 p.m. EST. About the Seminar This seminar Read More...

06/06/2023 - Dr. Maximilian Haeussler is the co-PI for the  UCSC Genome Browser , an interactive website offering access to genome sequence data from a variety of vertebrate and invertebrate species and major model organisms, integrated with Read More...

02/07/2023 - The National Cancer Institute (NCI) is holding a virtual meeting on February 7-8, 2023 from 12 - 4 PM ET, Variation to Biology: Optimizing Functional Analysis of Cancer Risk Variants , to identify and discuss how best to Read More...

10/04/2022 - Speaker: Luis G. Carvajal-Carmona, Ph.D. Professor and Auburn Community Cancer Endowed Chair in Basic Science Department of Biochemistry and Molecular Medicine UC Davis Health School of Medicine Dr. Luis Carvajal-Carmona is Professor and Read More...

10/04/2022 - Speaker: Steven D Cappell NIH Stadtman Investigator Center for Cancer Research – National Cancer Institute – Bethesda MD My laboratory is integrating quantitative image analysis with genetic, biochemical, and systems biology approaches to understand how cells Read More...

10/11/2021 - This course uses lectures, demos, and hands-on labs to give you an overview of Google Cloud products and services so that you can learn the value of Google Cloud and how to incorporate cloud-based Read More...

08/11/2021 - Registration is required to join this event. If you have not registered, please do so now. Efforts are underway to characterize cancer cell lines and identify their genetic and pharmacological vulnerabilities, but integration is Read More...

03/08/2021 - Zoom Registration Description NHGRI will host a new seminar series this year on the “Bold Predictions for Human Genomics by 2030” that are described in NHGRI’s “ Strategic Vision for Improving Human Health at the Read More...

The Animal Diagnostic Laboratory (ADL) provides a full range of diagnostic capabilities, including microbiological cultures on various culture medium, microscopic screening for parasites such as mites and pinworms, molecular detection of pathogens, serological evaluation of Read More...

The Division of Veterinary Resources’ (DVR) mission is to contribute to the advancement of NIH biomedical research programs by providing excellence in animal care, customer service, and specialized research services to support intramural research efforts. Read More...

The Pharmacogenetics Core is responsible for correlating outcome observations (toxicity, efficacy, survival, PK/PD) with genetic variants (germline or somatic) to identify key genetic determinants and biomarkers that predict response to specific treatments. We also Read More...

The NCI Clinical Research Correlatives Core provides non-CLIA-certified spectral flow cytometric assays to support clinical trials conducted in the CCR. The core specializes in immunophenotyping and immune monitoring assays. Established Technologies Spectral flow cytometry (Cytek), Read More...

Let's submit a batch job. We are going to download data from the Sequence Read Archive (SRA), a public repository of high throughput, short read sequencing data. We will discuss the SRA a bit Read More...

03/25/2025 - Dr. Ben Raphael will describe computational methods developed in his lab to analyze large-scale biological data related to cancer evolution, genetic variants, and structural variation in cancer genomes. He’ll share combinatorial and statistical Read More...

10/10/2024 - Digital Pathology has advanced significantly in the past decade, evolving beyond assisting pathologists to now informing molecular and genetic properties of tumors. Recent breakthroughs in machine learning and AI, particularly in big data and Read More...

https://www.zymoresearch.com/blogs/blog/microbiome-informatics-otu-vs-asv www.drive5.com Elbrecht V, Vamos EE, Steinke D, Leese F. 2018. Estimating intraspecific genetic diversity from community DNA metabarcoding data. PeerJ 6:e4644 https://doi.org/10.7717/peerj.4644

The field has moved to denoising sequences rather than OTU clustering. In a denoising approach, the exact biological sequence is inferred and noise is removed from the dataset via error correction. This is generally done Read More...

11/21/2023 - Dear Colleagues,    This presentation will provide an overview of OpenCRAVAT.   Annotation and interpretation of cancer variants is critical to the design of personalized molecular therapies, and Read More...

09/13/2023 - FORGEdb is a web-based tool that can rapidly integrate data for individual genetic variants, providing information on associated regulatory elements, transcription factor (TF) binding sites and target genes for over 37 million variants.   Read More...

09/12/2023 - Animal models are used to study the development and progression of diseases and to test new treatments. Model organisms are a subset of research organisms that serve as a proxy for understanding human biology. Read More...

Genomic variations are typically categorized into different classes and are often denoted with a shortened acronym: SNP, a single nucleotide polymorphism - A change of a single base. INDEL, an insertion or a deletion - Read More...

04/18/2023 - Efforts are underway to characterize cancer cell lines and identify their genetic and pharmacological vulnerabilities, but integration is essential for their interpretation. To empower researchers, to utilize the growing knowledge from these hundreds of Read More...

03/31/2023 - Alejandro Schäffer, Ph.D., was born in Montevideo, Uruguay, and emigrated with his parents to the United States. He received his B.S. in Applied Mathematics and his M.S. in Mathematics from Read More...

11/17/2022 - Join Icahn School of Medicine at Mount Sinai’s Dr. Zeynep Gümüş to learn about a user-friendly tool she and her team are developing to enable researchers of all computational skill levels to Read More...

03/23/2022 - Please join us on March 23 when Ben Raphael, Ph.D., will present “Quantifying Tumor Heterogeneity Using Single-Cell and Spatial Sequencing.” In this presentation, Dr. Raphael will describe computational approaches to quantify tumor heterogeneity and Read More...

06/18/2021 - Animal models are used to study the development and progression of diseases and to test new treatments. Model organisms are a subset of research organisms that serve as a proxy for understanding human biology. Read More...

05/17/2021 - Register Session Description Animal models are used to study the development and progression of diseases and to test new treatments. Model organisms are a subset of research organisms that serve as a proxy for Read More...

04/28/2021 - Register/Join In this public workshop, participants will have the opportunity to discuss the challenges and opportunities involved in establishing effective data management and sharing practices. The organizers encourage anyone working with data to Read More...

04/19/2021 - Registration Session Description Animal models are used to study the development and progression of diseases and to test new treatments. Model organisms are a subset of research organisms that serve as a proxy for Read More...

01/04/2021 - Abstract: Phenotypic heterogeneity in cancer is often caused by different patterns of genetic alterations. Understanding such phenotype-genotype relationships is fundamental for the advance of personalized medicine. In this talk, I will present a computational Read More...

12/02/2020 - Register Visualizing biological data can be challenging. Heat maps are useful for showing the basic distribution of gene expression but interactivity is needed for additional, in-depth analysis. Clustergrammer2 is a visualization tool that allows Read More...

02/12/2020 - This two-day instructor-led course gives participants a broad study of networking options on Google Cloud Platform. Through presentations, demonstrations, and hands-on labs, learners explore and deploy GCP networking technologies, such as Google Virtual Private Read More...

Bioinformatics integrates biology, statistics, and computer science to develop and apply theory, methods, and tools for the collection, storage, and analysis of biological and related data. Some key application areas in bioinformatics include genomic and Read More...

Bioinformatics integrates biology, statistics, and computer science to develop and apply theory, methods, and tools for the collection, storage, and analysis of biological and related data. Some key application areas in bioinformatics include genomic and Read More...

DAVID pulls disease annotations from different sources. Clicking on the Chart button will take us to a chart view showing the disease records from a given database in which our input genes map. DISGENET GAD_ Read More...

IPA takes tabular data as input. Differential gene expression data should contain columns with gene names, log fold change, and p value. We can also provide a table with genetic gain/loss of function information Read More...

The Division of Veterinary Resources Animal Surgery has supported large animal research and clinical care for more than 40 years. DVR surgeons provide outstanding and highly specialized large animal (rabbits, ungulates, etc.) research support in a Read More...

The Crystallization Facility provides an automated environment for setting up crystallization experiments in a high-throughput format, storing the resulting plates under controlled conditions, and monitoring the status of prepared droplets remotely. The Facility is in Read More...

The Stem Cell Unit (SCU) has established a database to which hESC lines, adult stem cells and induced pluripotent stem (iPS) cells may be directly compared. These data give scientists the information they need when Read More...

The Office of Collaborative Biostatistics, Office of the Clinical Director, is the statistical and data management component of CCR. The Section provides statistical leadership and data management consultation for CCR’s major clinical activities and Read More...

In support of Intramural Research Program (IRP) scientists, DOHS provides training, consulting, and resources to ensure that workers' risk to hazards and stresses in the laboratory environment is minimized. Our services include one-on-one consultation with Read More...

In support of Intramural Research Program (IRP) scientists, DOHS provides training, consulting, and resources to ensure that laboratory equipment is used and maintained properly and safely. We provide expert safety and health consulting support for Read More...

The National Cancer Institute (NCI) is developing a national repository of Patient-Derived Models (PDMs) comprised of patient-derived xenografts (PDXs), patient-derived organoids (PDOrg), and in vitro patient-derived tumor cell cultures (PDCs) and cancer-associated fibroblasts (CAFs). These Read More...

The NIH Clinical Center Pharmacy Department provides pharmaceutical care to inpatients and outpatients on NIH intramural research protocols at the NIH Clinical Center. The Clinical Center facility encompasses 200 inpatient beds, 93 day-hospital stations, and 15 clinics. Clinical Read More...

The Blood Processing Core monitors viral load in patients with HIV and performs sequential studies using samples obtained from patients with cancer, AIDS, chronic granulomatous disease, or other diseases associated with immunologic dysfunction. The core Read More...

NCI LASP Animal Research Technology Support (ARTS) provides customized technical support for basic and translational animal-based research to the scientific community. We offer a wide array of services ranging from expert colony management to the Read More...

Protein Characterization Laboratory (PCL) offers various technologies to CCR investigators to characterize proteins and metabolites. The laboratory develops and applies state-of-the-art analytical technologies, primarily mass spectrometry, liquid chromatography, and Surface Plasmon Resonance (SPR), to advance Read More...

07/09/2025 - From image analy i to federated learning and multimodal modeling, generative AI can be u ed to tudy ob ervational ucce ion acro cale and data type . At DCEG' Data cience and Engineering Re Read More...

This is part II of the article highlighting nf-core pipelines and specifically addresses the use of these pipelines in the DNAnexus cloud environment. Part I of the article can be found in the October 2023 topic Read More...

01/22/2025 - Alzheimer’s Disease (AD) presents significant challenges in prevention and treatment despite decades of research advancements. Innovative AI/ML approaches enable analysis of real-world data sources, such as electronic health records (EHRs) Read More...

01/10/2025 - NIH DIRECTORS SEMINAR SERIES In this presentation, Dr. Scholz will discuss the approach to tackling complex neurodegenerative diseases using modern genomic tools, focusing on Lewy body dementia, a major research area in her lab. Read More...

10/24/2024 - NIH Text Mining and Natural Language Processing SIG is pleased to welcome you to this special event featuring two extraordinary speakers focused on the applications of Deep Learning in Computational Biology.  & Read More...

10/16/2024 - Dear Colleagues,   Thanks to advances in single-cell genomics, researchers can construct large-scale organ atlases, giving you more accurate ways to study genetic mutations and alterations related to drug responses and disease. These Read More...

03/29/2024 - This first of five webinars will introduce NIH’s All of Us Research Program, including the program’s mission and core values. Learn about the current size and diversity of Read More...

01/23/2024 - Looking for  data sharing  platforms to enhance your research and advance communal knowledge of childhood cancers? Join the first NCI Childhood Cancer Data Initiative (CCDI) webinar of the new year! Read More...

01/19/2024 - Trey Ideker, Ph.D., is a professor of medicine, bioengineering, and computer science, and former chief of genetics at the University of California San Diego (UCSD). Additionally, he is director or co-director of the Read More...

An OTU is an operational taxonomic unit. This is derived by binning sequences at a certain threshold of similarity. This threshold is generally set at 97%, which is associated with a species level assignment. Clustering can Read More...

11/14/2023 - Dr. Ting Wang is a Sanford C. and Karen P. Loewentheil Distinguished Professor of Medicine at the McDonnell Genome Institute, Washington University School of Medicine in St. Louis. Dr. Wang’s lab Read More...

11/06/2023 - UK Biobank is a large-scale biomedical database and research resource, containing in-depth genetic and health information from half a million UK participants. The database is regularly augmented with additional data and is globally accessible Read More...

Let's submit a batch job. We are going to download data from the Sequence Read Archive (SRA) , a public repository of high throughput, short read sequencing data. We will discuss the SRA a bit Read More...

Variant annotation means predicting the effects of genetic variants (SNPs, insertions, deletions, copy number variations (CNV) or structural variations (SV)) on the function of genes, transcripts, and protein sequence, as well as regulatory regions. The Read More...

This page uses context taken directly from the Biostar Handbook by Istvan Albert. Remember to activate the class bioinformatics environment. conda activate bioinfo Introduction to Genomic Variation Genomic variations are typically categorized into different classes Read More...

The bulk RNA-Seq test data we've been working with is in FASTQ format. We'd like to do a BLAST search on a couple of these sequences. Data must be in FASTA format to Read More...

This page uses content directly from the Biostar Handbook by Istvan Albert. Always remember to activate the bioinfo environment when working on Biostar class materials. conda activate bioinfo The bulk RNA-Seq test data we've Read More...

08/03/2023 - Identification of evolutionarily related DNA or protein sequences (homologs) is a crucial step in many biology workflows. For example, homologous sequences are used to infer relationships between organisms, understand how sequence changes affect observable Read More...

03/30/2023 - AI Models of Cancer and Precision Medicine: Building a Mind for Cancer The long-term objective of the Ideker Lab is to create artificially intelligent, mechanistic models of cancer and neurodegenerative diseases for translation of Read More...

11/14/2022 - During this webinar, the  Genomic Data Commons ’ (GDC’s) Drs. Zhenyu Zhang and Bill Wysocki will review the different types of harmonized data that the GDC makes available for the cancer research community. The Read More...

11/09/2022 - Speakers: Amanda Phipps, PhD, MPH Associate Professor and Associate Chair of Epidemiology Department of Epidemiology University of Washington School of Public Health Tabitha Harrison, MPH Research Scientist University of Washington School of Public Health Read More...

11/09/2022 - Over the past decade the importance of Structural Variation (SV) is becoming more obvious not just for population diversity but also with clear impacts in multiple diseases (e.g. Neurological) as well as cancer.  Read More...

09/21/2022 - Join University of Colorado’s Dr. Arjun Krishnan as he discusses how machine learning and natural language processing can contribute to making public -omics data more accessible. Dr. Krishnan will also present the recent Read More...

09/07/2022 - In this session of the University of Alabama at Birmingham’s O’Neal Research Seminar Series, CBIIT’s Dr. Jill Barnholtz-Sloan will share how  big data  has provided insight on brain and central nervous Read More...

05/04/2022 - Presenter: Thomas Gonatopoulos-Pournatzis, Ph.D. Stadtman Investigator NIH Distinguished Scholar Head Functional Transcriptomics Section RNA Biology Laboratory NCI-Frederick Dr. Gonatopoulos-Pournatzis studies the regulatory pathways and functional roles of alternative splicing and other pre-mRNA processing Read More...

10/14/2021 - Meeting Link Forward genetic screens using CRISPR (clustered regularly interspaced short palindromic repeats)–associated nucleases like Cas9 are a powerful tool to pinpoint genes involved in disease. Initial screens capitalized on genome-scale libraries to Read More...

07/12/2021 - Registration is required for this event Register Here NHGRI will host a new seminar series this year on the “Bold Predictions for Human Genomics by 2030” that are described in NHGRI’s “Strategic Vision for Read More...

06/17/2021 - The intrinsic stochasticity of transcription leads to gene expression variation across cells in a clonal cell population. The expression variation can translate into phenotypic variation that can persist through several rounds of cell division. Read More...

06/10/2021 - Meeting Link:  https://cbiit.webex.com/cbiit/j.php?MTID=mc11b56eb7f7e732aa44c78427402dd2e Abstract: Long read, single molecule sequencing from Pacific Biosciences (PacBio) and Oxford Nanopore are revolutionizing Read More...

05/03/2021 - Abstract: We will discuss technical advantages of a personalized and tumor-informed multiplex PCR next generation sequencing assay, called Signatera™, that enables a sensitive, specific, and dynamic detection of molecular disease burden in cell-free DNA ( Read More...

04/05/2021 - Dear colleagues, We'll be hosting a special guest lecture by Prof. John Moult from UMD. Abstract: Computing the three-dimensional structure of a protein molecule from its amino acid sequence is a long-standing grand Read More...

03/11/2021 - Abstract: Targeted quantitative proteomics using multiple/parallel reaction monitoring (MRM, PRM) is already being applied by many researchers in biology, biochemistry, and clinical research laboratories. These methods allow rapid and precise quantitation of proteins Read More...

03/05/2021 - Overview: The Human Cell Atlas (HCA) is an ambitious global initiative that aims to create a comprehensive reference map of all human cells—the fundamental units of life—as a basis for both understanding Read More...

02/22/2021 - coming Monday we'll be having a guest lecture by Dr. Jian Peng from UIUC. Abstract: Recent advances in functional genomics have enabled large-scale measurements of molecular interactions, functional activities, and the impact of Read More...

02/17/2021 - Speaker is Dr. Michal Linial from the Hebrew University of Jerusalem, Israel. Abstract: Incredible progress has also been made in the field of cancer genetics with the sequencing and molecular profiling of tens of Read More...

02/08/2021 - Dear colleagues, Coming Monday, Feb 8th, we'll be having a guest lecture by Prof. Vineet Bafna from UCSD. Abstract: Increase in the number of copies of tumor promoting (onco-) genes is a hallmark Read More...

01/25/2021 - Presenter: Dr. Arjun Raj from the Perelman School of Medicine, UPenn. Abstract:Anti-cancer therapies can often kill the vast majority of tumor cells but a few rare cells remain and grow despite treatment. Non-genetic Read More...

11/16/2020 - Register Cancer heterogeneity is one of the major challenges that hampers the ability to cure the disease. Tumors differ in their genetic profiles and the cellular interactions in the microenvironment, and each tumor may Read More...

06/16/2020 - The capability to unambiguously and comprehensively identify thousands of metabolites and other chemicals in clinical samples, including the microbiome, will revolutionize the search for environmental, dietary, and metabolic determinants of health and disease. By Read More...

02/27/2020 - The Annotation, Visualization and Impact Analysis (AVIA) is an application developed to guide, prioritize and summarize genomic variants. AVIA maintains and aggregates dozens of publicly available variant annotation databases and predictions from impact analysis Read More...

11/04/2019 - This is a hands-on demo, please bring your laptop or let us know if you need to borrow one.  The field of genomics has matured to a stage where organizations are sequencing DNA at Read More...

10/26/2018 - Variant Analysis using Genomatix GeneGrid ** please bring laptop with Flash installed for the hands-on portion of this demo Susan M. Dombrowski, PhD and Peter Grant, Genomatix, Inc. Genomatix GeneGrid is a variant annotation and Read More...

06/16/2000 - We present the AMARETTO-Hub as a Knowledge Graph-based software platform that leverages Neo4j and Shiny to embed and interactively interrogate results generated by the *AMARETTO software toolbox that offers modular and complementary solutions Read More...

The Genomics Laboratory (formerly Laboratory of Molecular Technology) is an integrated, high-throughput molecular biology laboratory focusing on the development of genetics and genomics technologies, together with associated laboratory automation systems, data analysis, and information management Read More...

Back Services: Biophysics Facility offers DSC as an open-access instrument. First-time users must complete training before gaining access to the instrument reservation calendar. Location: Building 50, room 3123 Description: The differential scanning calorimeter measures the constant pressure Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More. New Resources on CREx NIMH Human Brain Collection Core (HBCC) The HBCC obtains human brain tissue, hair, and blood Read More...

[embed]https://youtu.be/yTl1Q0D7aZ0[/embed] 10x Genomics' supports multiple cancer research areas from single nucleotide and structural variant detection to single cell whole transcriptome gene expression analysis of thousands of individual Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New Resources on CREx NCI CLIA Molecular Diagnostics Laboratory (CMDL) The NCI CMDL is available to assist all Read More...

CREx News & Updates February 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight ORS Division of Veterinary Resources (DVR) DVR is the central NIH lab animal support program Read More...

The Mouse Metabolic Phenotyping Center (MMPC)Live Program provides standardized, high quality, unique, and hard to find phenotyping services for mouse models of diabetes, obesity, and related metabolic disorders. Emerging as the next iteration of Read More...

The CCR-Frederick Flow Cytometry Core Facility provides research support to the Frederick-CCR community, including cytometry analysis and sorting services, instrument maintenance, new user training, and technical consultation. Typical Assays Performed by Core Instruments Immunophenotyping of Read More...

NISC’s role within NHGRI, and more broadly across NIH, aims to advance genome sequencing and its many applications, with a goal not simply to produce sequence data, but to produce the infrastructure required to Read More...

The Department of Laboratory Medicine provides state-of-the-art laboratory testing in support of Clinical Center patient care and will serve as a center of excellence in research and training in laboratory medicine, particularly in areas which Read More...

The FNLCR Molecular Histopathology Laboratory (MHL) provides comprehensive veterinary pathology support for animal health monitoring, biomarker discovery and validation, drug development, genomics, and proteomics on a cost recovered basis. The MHL is organized into multiple Read More...

The CCR Building 41 Flow Cytometry Core is a full-service facility within the Center for Cancer Research that supports over 150 users representing 26 laboratories. The Core Facility provides instrument and software training, technical expertise, assay development, and Read More...

CREx News & Updates March 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight NIA Nonhuman Primate Core The NIA Nonhuman Primate Core supports multi-disciplinary translational aging projects for Read More...

The NHLBI Transgenic Core’s main mission is to keep up with the latest advancements in genome engineering technologies and to provide state-of-the-art services to assist NIH scientists in generating genetically engineered animal models. In Read More...

CREx News & Updates July 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Click below to learn how easy it is to navigate the CREx platform. These short videos will Read More...

CREx News & Updates January 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight NCI ANTIBODY CHARACTERIZATION LABORATORY (ACL) The ACL specializes in rigorously validating antibodies for signaling and Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx User Survey The CREx Team is carrying out a CREx User Survey. We would greatly appreciate Read More...

The CLIA Molecular Diagnostics Laboratory (CMDL) provides an array of services for groups at the NIH Clinical Center, Fort Detrick, and Hood College, among others. They support cancer- and disease-related research by making Read More...

The Clinical Image Processing Service (CIPS) offers timely and accurate advanced image processing of diagnostic radiology images for clinical care, research, and training. CIPS’ functions include clinical services and scientific researches. Established Technologies: CIPS can Read More...

The CCR Genomics Core is located in Building 41 on the NIH Bethesda campus. The primary goal of the Core is to provide investigators from CCR/NCI and other NIH Institutes access to genomic technologies and Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx User Survey The CREx Team is carrying out a CREx User Survey. If you haven’t Read More...

The Chemistry and Synthesis Center (CSC) of the National Heart, Lung, and Blood Institute (NHLBI) provides IRP scientists with targeted imaging probes and chemical tools that help accelerate cell-based assays, in vivo imaging studies, and Read More...

The Biophysics Core’s mission is to provide support in the study of macromolecular interactions, dynamics, and stability by offering consultations, training, professional collaborations, and instrument access. General Services Multi-technique molecular interaction studies, Kinetic and Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Research Festival The NIH Research Festival highlights the groundbreaking science and the vibrant NIH community driving our Read More...

The Clinical Support Laboratory offers processing, tracking, and testing of a broad range of clinical samples. Support can begin at the early stages of clinical trial development to aid in developing a comprehensive strategy for Read More...

The mission of Human Brain Collection Core (HBCC) within the National Institute of Mental Health, Division of Intramural Programs (NIMH IRP) is to conduct and support research on brain and behavior, with the goal of Read More...

The Laboratory Animal Sciences Program (LASP) of the Frederick National Laboratory operates a Gnotobiotics Facility (GF) to support research focused on the role of microbiota in cancer inflammation, pathogenesis, and treatment response. The GF can Read More...

The research conducted within the Synthetic Biologics Core (SBC) Facility has a dual role: Generate chemical biology tools and drug candidates for molecular targets identified by NCI research groups, Develop novel effective methods and tools Read More...

CLIA-Certified Technologies Offered: Fragment Analysis for Micro-satellite Instability Detection, Pharmacoscan Array for Pharmacogenomics, Mutation Detection for PCR and Sanger Sequencing, DNA extraction from whole blood, saliva, FFPE tissues, buccal swabs, nails, hair, PBMCs, buffy coats, Read More...

CREx News & Updates December 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight FACILITY HIGLIGHTS Learn more about services from the STRIDES Initiative. VIEW STRIDES INITIATIVE NIH Cores Read More...

The Genomics Technology Laboratory is an integrated, high-throughput molecular biology laboratory focusing on the development of genetics and genomics technologies, data analysis, and information management tools, in support of CCR Investigators. The laboratory develops integrated Read More...

CREx News & Updates May 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Click below to learn how easy it is to navigate the CREx platform. These short videos will Read More...

The facilities at AIM are available for use by the entire NIH intramural research community. While we welcome users with any size imaging project, AIM specializes in large, yearlong (or longer), collaborative research efforts with Read More...

The AgingResearchBiobank was officially launched in January 2019 with a mission to provide a state-of-the-art inventory system for the storage, maintenance, and distribution of de-identified biospecimens and associated phenotypic, clinical, and imaging data from numerous NIA-funded Read More...

The Pan-Microbial Serology Facility (PMSF) is part of the Center for Cancer Research (CCR) at the National Cancer Institute (NCI). The PMSF focuses on determining individualized pan-microbial immune profiles associated with human diseases including immunological Read More...

The OSTR offers cutting-edge technology platforms to the CCR scientific community through centralized facilities. The videos accessed through this page are designed to introduce the various scientific methodologies OSTR makes available through the cores on Read More...

The computational chemistry and protein modeling team in the Advanced Biomedical Computational Science (ABCS) group provides novel solutions in structural modeling and computational chemistry. Computational scientists in the group collaborate with NCI researchers by using Read More...

Long read sequencing was recently named 2022’s method of the year by Nature Methods . Long read sequencing technologies, those that generate sequence reads with lengths of 10s of kilobases or longer have several advantages over Read More...

Lesson 3: Creating a feature table Lesson Objectives Check for primers Generate an ASV count table and representative sequence file Understand the difference between OTU picking and denoising The two primary files that will be used Read More...

Lesson 5: Working on Biowulf Lesson 4 Review Flags and command options Wildcards ( * ) Tab complete Accessing user history with the "up" and "down" arrows cat , head , and tail Working with file content (input, Read More...

04/03/2023 - Workshop Description:  The application of AI to cancer research holds promise to accelerate new discoveries, enable early detection, improve diagnosis, and spur development of new therapies for cancer. Machine learning and other forms of Read More...

06/06/2016 - The 'NCBI Resources for CCR Scientists' workshop, on June 6 and June 8, 2016, will focus on teaching a wide range of resources developed within NCBI that are relevant for CCR scientists. It will include both hands-on Read More...

03/18/2015 - This workshop will cover basics of exome-seq analysis including downstream interpretation of variants using a variety of open-source and commercial webtools (Golden Helix, IGV, Ingenuity Variant Analysis, GeneGrid (Genomatix), MuPit/Cravat). Day 1 - AM (9:30 Read More...