Search Results for: micro contact printing

RNA-SEQ Overview What is RNASEQ ? RNA-Seq (RNA sequencing), uses next-generation sequencing (NGS) to reveal the presence and quantity of RNA in a biological sample at a given moment. (Wikipedia) Strictly speaking this could be any Read More...

03/25/2025 - Agreement Across 10 Artificial Intelligence Models in Assessing HER2 in Breast Cancer Whole Slide Images: Findings from the Friends of Cancer Research Digital PATH Project For more information, please contact Aniruddha Ganguly, Ph.D.

11/26/2024 - This talk will introduce quantum chemistry and how it is useful for the modeling of therapeutic and diagnostic agents. This session is geared towards beginners. This session will be recorded, and materials will be Read More...

Dataquest licenses are no longer available. If you currently have a Dataquest license, you can continue using it until Sept 15, 2025. The Coursera platform contains thousands of courses developed by experts all over the world and Read More...

09/18/2024 - Learn how to use the FlowJo™ workspace, including how to load files, evaluate sample quality, draw gates, and generate tabular and graphical layouts.   Designed for those new to the software Read More...

08/27/2024 - This hands-on workshop will help you advance your microbiome analysis and computing skills, and help you learn new ways to leverage computing resources for your research. What you’ll learn: ● The basics of interacting Read More...

Additional Resources BTEP scRNA-Seq FAQs Training modules available on Github Orchestrating Single Cell Analysis with Bioconductor Single Cell Best Practices 2023 BTEP Single Cell Annotation Seminar Series Event recordings are located in the BTEP Video Archive . Read More...

05/28/2024 - Frederick Research Computing Environment (FRCE) and Computational Sciences Series In this session, we will explore how machine learning can be used to analyze whole slide pathological images (WSIs). We will showcase how to utilize Read More...

05/28/2024 - The symposium's goals are to explore the integration of AI in understanding and managing immunological data, foster a paradigm shift in how immunologists leverage AI to propel their research forward, and inform NIAID Read More...

02/27/2024 - This session will cover what are containers, and why and how to use them in your Bioinformatics workflows. We will review best practices, basic commands, and useful resources. This session is geared towards beginners.& Read More...

The CLIA Molecular Diagnostics Laboratory (CMDL) provides an array of services for groups at the NIH Clinical Center, Fort Detrick, and Hood College, among others. They support cancer- and disease-related research by making Read More...

The Cancer and Inflammation Program – Microbiome and Genetics Core (CIP-MGC) grew out of the former CIP Genetics Core to meet the increasing need for sequencing and analysis of commensal microbiota within CIP and NCI. The Read More...

Protein Expression Laboratory The Protein Expression Laboratory develops, improves, and delivers protein-centric services. Our goal is to help client investigators achieve their research goals with the lowest possible cost in the shortest time. All PEL Read More...

In support of Intramural Research Program (IRP) scientists, DOHS provides training, consulting, and resources to ensure that workers' risk to hazards and stresses in the laboratory environment is minimized. Our services include one-on-one consultation with Read More...

07/16/2025 - All Biowulf users, and all those interested in using the systems, are invited to call in to our Virtual Walk-in Consult to discuss problems and concerns, from scripting problems to node allocation, to strategies Read More...

06/11/2025 - All Biowulf u er , and all tho e intere ted in u ing the y tem , are invited to call in to our Virtual Walk-in Con ult to di cu problem and concern , from Read More...

05/27/2025 - Agentic AI is a class of artificial intelligence that acts autonomously to make decisions and take actions to achieve specific goals. During this event, the participants will discuss the emerging role of AI agents Read More...

01/28/2025 - This talk will cover how our group uses the resources of the FRCE cluster to process cryo-electron microscopy data collected in-house. This session is geared towards beginner users. This session will be recorded, and Read More...

01/27/2025 - NCI CCR Liver Cancer Program Seminar Series Dr. Sethupathy is professor of physiological genomics and chair of the Department of Biomedical Sciences at Cornell University. He leads a research lab focused on genome-scale and Read More...

01/22/2025 - Join us for a one-hour talk investigating tumor signatures in the BRCA dataset by utilizing the CCBR Single-Cell RNA-seq Workflow on NIDAP. This talk will take you through an analysis of a publicly available Read More...

01/14/2025 - In this talk, we will cover the basics of survival analysis as a statistical methodology developed for censored data. Special emphasis will be on visualizing survival data, comparing survival-time distributions for subject groups, and Read More...

01/08/2025 - Helen Shearman, Ph.D., Senior Field Application Scientist, will be presenting a one-hour overview demonstration on SnapGene.   SnapGene offers a fast and easy way to plan, visualize, and document your everyday cloning Read More...

Register now for an upcoming seminar on January 22, 2025 , “Revealing Tumor-Promoting Signals in Breast Cancer Subtypes: A NIDAP Analysis of Single-Cell Data” . This one-hour talk will feature guest speaker and NIDAP developer, Josh Meyer, who will Read More...

01/07/2025 - You’re invited to the ChIRP Launch Event! On January 7, 2025, the Office of Intramural Research (OIR) and the Clinical Research Informatics Strategic Planning Initiative (CRISPI) are hosting the virtual Launch Event for Read More...

12/13/2024 - The National Cancer Institute has been working with central cancer registries, medical and pharmacy claims processors, and healthcare providers like children's hospitals, NCI-supported Cancer Centers, and radiation oncology providers through the National Childhood Read More...

12/04/2024 - Galaxy is a web-based computational workbench for analyzing and visualizing biomedical datasets that is used by thousands of scientists daily.   Galaxy enables accessible, reproducible, and scalable biomedical data science by any scientist Read More...

12/03/2024 - Sequencing Strategies for Population and Cancer Epidemiology Studies (SeqSPACE) Webinar Series The Sequencing Strategies for Population and Cancer Epidemiology Studies (SeqSPACE) webinar series began 10 years ago in November 2014. The series was designed to share Read More...

11/26/2024 - Dr. Daniel Orringer received his M.D. from The Ohio State University, completed his residency in neurological surgery at the University of Michigan Health System, and fellowship training in neuro-oncology at the Massachusetts General-Brigham Read More...

11/21/2024 - Join this webinar to gain insights from Dr. Qi Long, who will explore how LLMs offer a promising solution to data issues, especially those stemming from incomplete information.   Dr. Long will share his team' Read More...

11/21/2024 - Dear FNL colleagues,   It’s time once again for our last in 2024 Biotech Connector event!!   The Frederick National Laboratory for Cancer Research together with the Frederick County Chamber of Commerce organizes the quarterly Biotech Read More...

11/13/2024 - This one-hour online training will cover several easy-to-use tools for analytic situations, including PROC FREQ (chi-square tests, Fisher's exact test), PROC TTEST, and PROC NPAR1WAY. This training covers the basic guidelines for Read More...

11/12/2024 - NCI staff are welcome to register for an upcoming Childhood Cancer Data Initiative (CCDI) webinar: "Live Demo: National Childhood Cancer Registry (NCCR) Data Platform." Join the NCCR Technical Lead Johanna Goderre, M. Read More...

11/12/2024 - We will discuss statistical considerations in planning, executing, and interpreting experiments using animals. Topics will include interpreting minimally powered pilot studies, dealing with complex time series, and maximizing knowledge gain from limited resources. This Read More...

10/29/2024 - In this presentation, you will get an overview of the Cancer Digital Slide Archive (CDSA) platform. CDSA is an open source, web-based platform for storage, visualization, and management of digitized whole slide images.& Read More...

10/23/2024 - This one-hour online training will cover tips and tricks to run your processing against large datasets more efficiently in SAS.   By the end of this training, attendees will be able Read More...

10/23/2024 - Please send any questions and/or specific topic areas that you’re interested in hearing about for this presentation by Friday, 10/18 to Kayla Strauss . QIAGEN Ingenuity Pathway Analysis (IPA) is the leading Read More...

10/22/2024 - Popular structure prediction program AlphaFold3 and its competitor Chai-1 recently added capabilities to predict 3D RNA structures straight from sequence input. In this talk, we will discuss some test cases for these programs and Read More...

10/16/2024 - Dear Colleagues,   Thanks to advances in single-cell genomics, researchers can construct large-scale organ atlases, giving you more accurate ways to study genetic mutations and alterations related to drug responses and disease. These Read More...

10/08/2024 - We will cover recently developed statistical approaches to the classification of BRCA2 variants using the functional-assay data generated by our NCI collaborators (Dr. Sharan’s lab). Our main objective is to illustrate how statistical Read More...

09/30/2024 - In this webinar, you'll gain insights into the Electronic Medical Record Search Engine (EMERSE). EMERSE is a simple, powerful tool to help researchers like you identify key data within free text clinical notes Read More...

09/18/2024 - This one-hour online training will cover several integration points between SAS and open-source tools to empower the developer and the organization to integrate the benefits of both SAS and open source. & Read More...

09/13/2024 - Reverse-phase protein arrays (RPPAs) represent a powerful functional proteomic approach to elucidate cancer-related molecular mechanisms and develop novel cancer therapies.   To facilitate community-based investigation of the large-scale protein expression data generated by Read More...

09/10/2024 - This introductory course teaches the basics of deep learning and of different types of deep learning networks through a set of hands-on biological examples implemented in Keras, one example per class. This class will Read More...

08/23/2024 - In this webinar, Dr. Carey will provide an introduction to Bioconductor for genomic data science.   Bioconductor.org enters its third decade as an NHGRI/NCI-funded resource for many aspects of genomic data Read More...

Please see https://bioinformatics.ccr.cancer.gov/btep/self-learning/ to sign up for a license. Contact ncibtep@nih.gov with any questions about obtaining a license. Did you know that CCR researchers have access to Read More...

08/14/2024 - In this introduction session, Dr. Yana Stackpole will discuss biologist-friendly ways to import and analyze RNAseq data in Qlucore, followed by integrated GSEA for biological interpretation.   She will pick a public cancer-related Read More...

08/13/2024 - NCI staff are welcome to register for an upcoming Childhood Cancer Data Initiative (CCDI) webinar titled, "CCDI Federated Data: Enhancing Data Discoverability," where you can learn about one of the newest advancements Read More...

08/13/2024 - This session will cover the basics of linear mixed-effects modeling as a method of regression analysis for clustered data. Special emphasis will be on the ideas behind random-intercepts and random-slopes modeling, and the discussion Read More...

07/25/2024 - Join us for an informative webinar on the GARDE software where Dr. Del Fiol will describe how GARDE works, how GARDE has been implemented to support population-based genetic testing, the GARDE chatbot, and results Read More...

07/23/2024 - In this presentation, we will demonstrate how to use enterprise data science platform to configure, run, share, and scale downstream bioinformatics and image analysis pipelines using cloud and HPC resources. This session is geared Read More...

07/19/2024 - The molecular mechanisms underlying many types of cancer involve aberrances in trans-acting factors and their binding to cis-regulatory elements to regulate gene expression. Techniques such as ChIP-seq, DNase-seq, and ATAC-seq are commonly used to Read More...

Partek Flow enables scientists to build comprehensive workflows for analyzing multi-omics high throughput sequencing data including DNA and variant calling, bulk and single cell modalities for RNA, ChIP, and ATAC, spatial transcriptomics, CITE, and immune Read More...

06/27/2024 - During this presentation, you will learn about the GenePattern ecosystem, an environment for accessible, reproducible research that has been serving the needs of the cancer genomics community since 2004. GenePattern hosts hundreds of genomics analysis Read More...

06/20/2024 - Clustered heat maps are widely used for visualizing patterns in molecular profiling data. But traditional, static heat maps have significant limitations when applied to large datasets (1000s of elements per axis). Presented in this Read More...

06/18/2024 - The rising popularity of spatial transcriptomics (ST) has prompted the development of numerous analysis methods, each varying in robustness and user accessibility. These diverse approaches could help provide a better understanding of the tumor Read More...

06/11/2024 - This talk will cover the basics of statistical resampling methods such as bootstrap, Monte Carlo, and permutations for estimating parameters and testing hypotheses.  We will discuss when you might want to use Read More...

06/10/2024 - Please join us for the next talk in our single cell and spatial interest group series.    Dr. Jasmine Plummer is a faculty member and the Director of St. Jude Children' Read More...

05/29/2024 - Dear Colleagues,   As machine learning permeates across biomedical research, achieving optimal accuracy demands more than just model deployment.  Join us for a webinar where we explore post-processing techniques designed to Read More...

The NIH Library provides expert guidance on bioinformatics, biostatistics, data visualization, and data curation throughout the research process. Explore a variety of classes, on-demand trainings, resources, and services related to data science and bioinformatics available Read More...

05/17/2024 - The NIH Artificial Intelligence (AI) Symposium will take place on Friday, May 17th, 2024, in Masur Auditorium in Building 10 on the Bethesda NIH campus. This event is open to all NIH members - registration and Read More...

05/15/2024 - In this one-hour webinar, you'll get a demonstration of DNASTAR Lasergene Software. DNASTAR offers software solutions for molecular biology, protein analysis, and genomics. This presentation will focus on an overview of the applications Read More...

05/14/2024 - This presentation will explain the difference between the mean and standard deviation of a set of values and the standard error of the mean. The parameters involved in comparing two normally distributed populations relative Read More...

05/10/2024 - Please join us for the May Data Sharing and Reuse Seminar featuring Dr. Ali Loveys and Fiona Meng from FI Consulting. They will be sharing their presentation on Laying the Foundation for AI-Ready Data. Read More...

05/07/2024 - Presented as part of the Sequencing Strategies for Population and Cancer Epidemiology Studies (SeqSPACE) Webinar Series Dr. Philip Lupo is a professor of pediatrics and hematology-oncology at Baylor College of Medicine. His lab focuses Read More...

04/26/2024 - Webinar attendees will hear tips and tricks to code efficiently in the Researcher Workbench using R and RStudio. Although Python and SAS are alternative programming languages available on the Researcher Workbench, this session will Read More...

04/26/2024 - Dear Colleagues,    In this webinar, you'll get an introduction to WebMeV. WebMeV aims to democratize bioinformatics analysis for biological sciences researchers.   The maturation of many bioinformatics processes Read More...

04/23/2024 - Crunching of large data requires large resources. Exploration of holobiont metagenomes is considered a “big data” project and here I’ll be describing how I used the FRCE Read More...

04/23/2024 - What’s the difference between “regular” statistics (i.e., what you may have been using in the past several years) and the “new” Bayesian Read More...

04/23/2024 - Dr. Stephanie Harmon obtained her Ph.D. in medical physics at the University of Wisconsin–Madison and did her postgraduate training at Leidos Biomedical Research where she worked within the Molecular Imaging Read More...

04/22/2024 - Dear Colleagues,    In this webinar, you'll get an introduction to XNAT. XNAT is an open-source platform for managing, processing, and sharing medical imaging and related data in research settings. & Read More...

04/19/2024 - In this webinar, attendees will learn the basics of using the All of Us Researcher Workbench’s point-and-click research tools, including how to create a workspace, how to build a cohort of All of Read More...

04/19/2024 - Dear Colleagues,    This webinar will introduce TumorDecon, a computational tool that's at an early stage of contributing to the intersection of bioinformatics and oncology.   TumorDecon aims to Read More...

04/16/2024 - GitHub is a powerful platform for tracking, sharing, and collaborating on software projects of all kinds. Whether you’re a bioinformatics analyst, a software engineer, or a biologist who sometimes codes, GitHub Read More...

04/12/2024 - This session will outline the All of Us Researcher Workbench registration process for NIH researchers. Access to the Researcher Workbench is free, and all registered researchers are provided $300 initial computational credits. Some analyses in Read More...

04/09/2024 - In this talk, we will cover what differentiates parametric and non-parametric statistics, tests/methods of both types for different data scenarios, when to use one vs. the other, and tradeoffs/pitfalls of each. This Read More...

03/27/2024 - On Wednesday, March 27th, at 9:00 a.m., in Building 37, Room 4041/4107, and online. In-person attendance is encouraged.  Dr. Khan is the Deputy Chief of the Genetics Branch and Head of the Oncogenomics Section, Read More...

03/26/2024 - In this session, we will discuss the potential of GPUs, and when and why to use GPUs on the Frederick Research Computing Environment (FRCE). We will explore the possibilities of GPU-accelerated AI applications and Read More...

03/26/2024 - Dear Colleagues,   Developed by expert statisticians and programmers, SUDAAN is a software package designed for researchers who work with study data. SUDAAN procedures properly account for correlated observations, clustering, weighting, stratification, and Read More...

03/20/2024 - Dear Colleagues,   cBioPortal is an open-access resource for interactive exploration of multidimensional cancer genomics data sets, currently providing access to data from >200,000 tumor samples collected from >400 published cancer Read More...

03/11/2024 - The goal of this exploratory workshop is to identify scientific and collaborative bridges between the communities of mathematical theory development and computational cancer biology research by bringing together mathematical theorists and cancer biologists from Read More...

NCI researchers can find instructions for accessing Partek Flow at https://bioinformatics.ccr.cancer.gov/btep/partek-flow-bulk-and-single-cell-rna-seq-data-analysis/ . But the things needed are A Biowulf (The High Performance Computing cluster) account — see here for information about Read More...

NCI researchers can find instructions for accessing Partek Flow at https://bioinformatics.ccr.cancer.gov/btep/partek-flow-bulk-and-single-cell-rna-seq-data-analysis/ . But the things needed are A Biowulf (The High Performance Computing cluster) account — see here for information about Read More...

The Bioinformatics Training and Education Program is pleased to announce the Artificial Intelligence in Biomedical Research at NIH Seminar Series . Starting on Feb 29, these monthly events will be recorded and made available in the BTEP Read More...

03/04/2024 - The NCI Cancer Imaging Program presents a new monthly webinar series highlighting advancements in our imaging community. Please join us for our next lecture in the series Dr. McNally earned her Ph.D. in Read More...

03/04/2024 - This class is designed for those who want to extend the basics of R Markdown and apply those skills in Quarto. Quarto is an open-source scientific and technical publishing system that offers multilingual programming Read More...

03/01/2024 - Jens Rittscher is Professor of Engineering Science at the University of Oxford with his appointment held jointly between the Institute of Biomedical Engineering and the Nuffield Department of Medicine. He is a group leader Read More...

02/29/2024 - The Consortium of Metabolomics Studies (COMETS) is a partnership of researchers from around the globe that promotes collaboration among prospective cohort studies that follow participants for a range of outcomes and perform metabolomic profiling Read More...

Let's use some functions. a. Use sum() to add the numbers from 1 to 10. {{Sdet}} Solution{{Esum}} sum ( 1 : 10 ) {{Edet}} b. Compute the base 10 logarithm of the elements in the following vector and save to an Read More...

Lesson 2 Exercise Questions: Base R syntax, objects, and data types Let's use some functions. a. Use sum() to add the numbers from 1 to 10. {{Sdet}} Solution{{Esum}} sum ( 1 : 10 ) {{Edet}} b. Compute the base 10 logarithm of Read More...

02/13/2024 - The first half of the session will briefly review statistics training resources available to the NCI based on feedback from previous Statistics for Lunch sessions. For the second half, we will have an open Read More...

01/24/2024 - Dear Colleague,   Helen Shearman, Ph.D., Senior Field Application Scientist, will be presenting a one-hour overview demonstration on SnapGene. SnapGene offers a fast and easy way to plan, visualize, and document your Read More...

01/23/2024 - In this session, we will discuss the potential of GPUs, and when and why to use GPUs on the Frederick Research Computing Environment (FRCE). We will explore the possibilities of GPU-accelerated AI applications and Read More...

The Functional Genomics Laboratory (formerly, the RNAi Screening Facility) of the National Center for Advancing Translational Sciences (NCATS) assist investigators with all stages of project planning and execution, beginning with assay development through genome-wide siRNA Read More...

The Spatial Imaging Technology Resource (formerly the Nanoscale Protein Analysis Section of the Collaborative Protein Technology Resource or CPTR) provides expertise and service in state-of-the-art protein analysis technologies to advance CCR research in basic discovery Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New NIH Resource Resources Advance your research with the NIH Mouse Imaging Facility (MIF) The NIH Mouse Imaging Read More...

Back Services: Biophysics Facility offers fluorometers as open-access instruments.  First-time users must complete a short training session before gaining access to the instrument reservation calendar. Location: Building 50, room 3226 Description: Some substances reemit light after Read More...

Thousands of molecular targets have been measured in the NCI panel of 60 human tumor cell lines. Measurements include protein levels, RNA measurements, mutation status, and enzyme activity levels. You can choose to search for a Read More...

The Specimen Resource Locator (SRL) is a biospecimen resource database designed to help researchers locate resources that may have the samples needed for their investigational use. This publicly searchable database includes information about biospecimen banks Read More...

The BRB Preclinical Biologics Repository is a central repository that supplies reagents to the broad research community. This NCI-sponsored repository is managed by NCI's Biological Resources Branch (BRB) in the Development Therapeutics Program (DTP) of Read More...

NCI LASP Genome Modification Core (GMC) is a CCR-dedicated facility that provides advice, training, and reagents to NCI scientists seeking to utilize CRISPR and other nucleases to generate genome modifications in primary cells, cell lines, Read More...

CLIA-Certified Technologies Offered: Fragment Analysis for Micro-satellite Instability Detection, Pharmacoscan Array for Pharmacogenomics, Mutation Detection for PCR and Sanger Sequencing, DNA extraction from whole blood, saliva, FFPE tissues, buccal swabs, nails, hair, PBMCs, buffy coats, Read More...

Biophysics Core Facility assists NIH investigators in measuring molecular interactions and in characterizing macromolecular properties. This includes binding studies of proteins, DNA, RNA, and their ligands in buffers, cell lysate, plasma, and other media. We Read More...

Back Services: Biophysics Facility offers Octet as an open-access instrument.  First-time users must complete a short training session before gaining access to the instrument reservation calendar.  Training includes a full analysis of a Read More...

Mass Spectrometry Section of the Collaborative Protein Technology Resource (Bldg. 37) Core Capabilities: Identification of proteins in complexes, organelles, subcellular fractions, or fluids. Global relative protein quantitation. Quantitation by isotopic labeling of cells in culture (SILAC) Read More...

The Mouse Modeling Core assists NIH investigators by generating and preserving genetically-engineered mouse strains. Services include scientific consultation, gene-targeting in mouse embryonic stem cells, micro-injection of nucleic acids, proteins, or ES cells into mouse embryos, Read More...

The CCR Molecular Modeling Core, under the direction of Dr. Stewart Durell, was established to provide a convenient way for experimentalists to take advantage of molecular modeling and computational biology. In the framework of consultations, Read More...

The Science and Technology Research Infrastructure for Discovery, Experimentation, and Sustainability (STRIDES) Initiative The STRIDES Initiative aims to help NIH and its institutes, centers, and offices (ICOs) accelerate biomedical research by reducing barriers in utilizing Read More...

The CCR-Frederick Flow Cytometry Core Facility provides research support to the Frederick-CCR community, including cytometry analysis and sorting services, instrument maintenance, new user training, and technical consultation. Typical Assays Performed by Core Instruments Immunophenotyping of Read More...

Home About the Biophysics Core Biophysics Core Technologies We provide consultations and advice on the applications of biophysical methods. If you would like to discuss the requirements of a particular technique or consider selecting the Read More...

What is Visium FFPE v2 with CytAssist? Visium FFPE v2 is sequencing-based spatial profiling technology developed by 10x Genomics. This assay can take mouse or human tissue sections on normal glass slides as input and Read More...

What is Xenium? Xenium is a high-resolution, imaging-based in situ spatial profiling technology from 10x Genomics that allows for simultaneous expression analysis of RNA targets (currently in range of 100’s) within the same tissue section. Read More...

CREx News & Updates August 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGHLIGHTS Learn more about services from the NHLBI Read More...

The core provides access to several different state-of-the-art 3D microscopes as well as computers to visualize and process image data. The facility houses equipment for 2D or 3D imaging of fixed and living specimens. High Read More...

The Crystallization Facility provides an automated environment for setting up crystallization experiments in a high-throughput format, storing the resulting plates under controlled conditions, and monitoring the status of prepared droplets remotely. The Facility is in Read More...

The NHLBI Murine Phenotyping Core carries out physiologic and behavioral testing in a diversity of mouse models for NHLBI and other NIH institutes. Established Technologies: Cardiovascular Phenotyping, Metabolic Phenotyping, Pulmonary Phenotyping, Behavioral Phenotyping, Exercise Physiology, Read More...

The CCR Collaborative Bioinformatics Resource (CCBR) is a centrally funded resource group which provides a mechanism for CCR researchers to obtain many different types of bioinformatics assistance to further their research goals. The group has Read More...

[embed]https://youtu.be/yTl1Q0D7aZ0[/embed] 10x Genomics' supports multiple cancer research areas from single nucleotide and structural variant detection to single cell whole transcriptome gene expression analysis of thousands of individual Read More...

CREx News & Updates September 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGLIGHTS Learn more about services from the CCR Read More...

CREx News & Updates January 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight NCI ANTIBODY CHARACTERIZATION LABORATORY (ACL) The ACL specializes in rigorously validating antibodies for signaling and Read More...

CREx News & Updates February 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight ORS Division of Veterinary Resources (DVR) DVR is the central NIH lab animal support program Read More...

CREx News & Updates June 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Click below to learn how easy it is to navigate the CREx platform. These short videos will Read More...

CREx News & Updates April 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Click below to learn how easy it is to navigate the CREx platform. These short videos will Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx Program Manager The CREx Team is happy to announce Deepika Velampati as the new CREx Program Read More...

The Chemical Synthesis Group is a component of the Chemical Biology Laboratory. This facility provides synthetic chemistry resources and expertise to the NCI Intramural community. The facility’s capabilities include: Providing expertise, consultation, and experience Read More...

Home About the Biophysics Core Biophysics Core Services [tabby title="Instrumentation"] NHLBI Biophysics Core The Biophysics Core Facility: Overview Core Facilities provide scientific resources, cutting-edge technologies and novel approaches to support DIR scientists. Availability of Read More...

CREx News & Updates March 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight NIA Nonhuman Primate Core The NIA Nonhuman Primate Core supports multi-disciplinary translational aging projects for Read More...

Total end-to-end system for single-cell research [embed]https://youtu.be/vMzhSzg1rUw[/embed] The BD Rhapsody Single-Cell Analysis system empowers and streamlines your research with a complete system of tools, including reagents and analysis software, Read More...

CREx News & Updates August 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight NCATS Functional Genomics Laboratory (FGL) FGL is designed to help NIH Investigators use the latest Read More...

CREx News & Updates December 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight FACILITY HIGLIGHTS Learn more about services from the STRIDES Initiative. VIEW STRIDES INITIATIVE NIH Cores Read More...

The Antibody Engineering Program (AEP) is part of the Center for Cancer Research (CCR) at the National Cancer Institute (NCI). The program focuses on generating therapeutic antibodies by phage display technology, including human antibodies and Read More...

DTP maintains a repository of synthetic compounds and pure natural products that are available to investigators for non-clinical research purposes. The Repository collection is a uniquely diverse set of more than 200,000 compounds that have been Read More...

CREx News & Updates July 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Click below to learn how easy it is to navigate the CREx platform. These short videos will Read More...

The Clinical Flow Cytometry Laboratory provides extensive support for NCI clinical protocols by providing diagnostic testing for leukemia and lymphoma in patients either on NCI clinical protocols or undergoing testing to determine eligibility for NCI Read More...

The Center for Advanced Tissue Imaging (CAT-I) is an NIAID and NCI supported effort involving collaborative studies between experts in the Laboratory of Immune System Biology, DIR, NIAID and investigators in the DIR, NIAID and Read More...

CREx News & Updates May 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Click below to learn how easy it is to navigate the CREx platform. These short videos will Read More...

The rapid advancement of single-cell technology has provided new powerful tools to answer many biological questions, such as identifying new or rare cell populations and characterizing the complexities of tumor heterogeneity. Realizing the great potential Read More...

The CCR Genomics Core is located in Building 41 on the NIH Bethesda campus. The primary goal of the Core is to provide investigators from CCR/NCI and other NIH Institutes access to genomic technologies and Read More...

CREx News & Updates October 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGLIGHTS Learn more about services from the CPTR Read More...

CREx News & Updates November 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight FACILITY HIGLIGHTS Learn more about services from the NINDS Quantitative Magnetic Resonance Imaging Core. NINDS Read More...

NIH Intramural CryoEM Consortium (NICE) serves intramural investigators in all NIH IC’s. NICE provides access to state-of-the-art Titan Krios cryo-electron microscopes for atomic-resolution structure determination of protein, macromolecular complexes, membrane receptors, cellular organelles, and Read More...

CCR VOLUME Electron Microscopy (CVEM) aims to develop new techniques in volume electron microscopy (vEM) and, in collaboration with CCR Investigators, apply these techniques to research cell biological questions well-suited for study by high-resolution 3D Read More...

NCI established the Nanotechnology Characterization Laboratory (NCL) to support the extramural research community to accelerate the progress of nanomedicine by providing preclinical characterization and safety testing of nanoparticles. It is a collaborative effort between NCI, Read More...

Protein Characterization Laboratory (PCL) offers various technologies to CCR investigators to characterize proteins and metabolites. The laboratory develops and applies state-of-the-art analytical technologies, primarily mass spectrometry, liquid chromatography, and Surface Plasmon Resonance (SPR), to advance Read More...

The Biopharmaceutical Development Program (BDP) provides resources for the development of investigational biological agents. The BDP supports feasibility through development and Phase I/II cGMP manufacturing plus regulatory documentation.The BDP was established in 1993. We Read More...

The Medicinal Chemistry Accelerator (MCA) is a collaborative CCR resource that supports investigators in developing small molecule inhibitors for anticancer drug candidates. While CCR and NCATS have infrastructure to identify initial “hits” through high-throughput screening, Read More...

The Biological Products Core provides the AIDS research community with high-quality purified preparations of various strains of Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV), economically prepared by leveraging the economy of scale. Materials Read More...

The centrally funded Statistics team within the Advanced Biomedical Computational Science group at the Frederick National Lab provides statistical consultation and data analysis support for NCI laboratories. We have broad-range expertise in biomedically relevant areas Read More...

The Behavioral Health Core (BHC) is comprised of the two separate but interrelated components: Psychosocial Support and Research Program, and, Health Psychology and Neurobehavioral Research Program., These teams provide specialized expertise, such as patient-reported and Read More...

.row { display: flex; justify-content: space-around; align-items: flex-start; margin: 20px; } .column { text-align: center; padding: 10px; width: 30%; } .column img { display: block; margin: 0 auto; width: 150px; height: 150px; } .column strong { display: block; margin-top: 10px; } Background: Intravital microscopy (IVM) Read More...

The Biophysics Resource (BR) was established in January 2001. Our mission is to provide CCR investigators with access to both the latest instrumentation and expertise in characterizing the biophysical aspects of systems under structural investigation. The Read More...

The OSTR offers cutting-edge technology platforms to the CCR scientific community through centralized facilities. The videos accessed through this page are designed to introduce the various scientific methodologies OSTR makes available through the cores on Read More...

The Antibody Characterization Laboratory (ACL) is the laboratory responsible for the development of well-characterized monoclonal antibody reagents. The NCI’s Office of Cancer Clinical Proteomics Research funds ACL as a resource to the entire cancer Read More...

CREx News & Updates July 2021   Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGHLIGHTS Learn more about services from the NHLBI Read More...

The research conducted within the Synthetic Biologics Core (SBC) Facility has a dual role: Generate chemical biology tools and drug candidates for molecular targets identified by NCI research groups, Develop novel effective methods and tools Read More...

The Genomics Laboratory (formerly Laboratory of Molecular Technology) is an integrated, high-throughput molecular biology laboratory focusing on the development of genetics and genomics technologies, together with associated laboratory automation systems, data analysis, and information management Read More...

OMAL focuses its research and development activities to quantitatively understand the molecular basis of three-dimensional (3D) cell organization, motility, invasion, and differentiation using fixed samples and live, 3D tissue culture models (i.e., translational models). Read More...

The Bloomington Drosophila Stock Center (BDSC) collects, maintains, and distributes genetically defined strains of Drosophila melanogaster for research and education. The BDSC supports a large, worldwide community of scientists using Drosophila as a model organism Read More...

The National Cancer Institute (NCI) is developing a national repository of Patient-Derived Models (PDMs) comprised of patient-derived xenografts (PDXs), patient-derived organoids (PDOrg), and in vitro patient-derived tumor cell cultures (PDCs) and cancer-associated fibroblasts (CAFs). These Read More...

The Trans-NIH Metabolomics Core (TNMC) is a shared research resource that performs metabolomics analysis (and related small molecule research) for investigators at all Institutes and Centers across the NIH Intramural Research Program. The TNMC is Read More...

The Chemistry and Synthesis Center (CSC) of the National Heart, Lung, and Blood Institute (NHLBI) provides IRP scientists with targeted imaging probes and chemical tools that help accelerate cell-based assays, in vivo imaging studies, and Read More...

In order to meet increasing demands from both NIH intramural and extramural communities for access to a small angle X-ray scattering (SAXS) resource, the Center for Cancer Research (CCR) under the leadership of Drs. Jeffrey Read More...

The Pan-Microbial Serology Facility (PMSF) is part of the Center for Cancer Research (CCR) at the National Cancer Institute (NCI). The PMSF focuses on determining individualized pan-microbial immune profiles associated with human diseases including immunological Read More...

NISC’s role within NHGRI, and more broadly across NIH, aims to advance genome sequencing and its many applications, with a goal not simply to produce sequence data, but to produce the infrastructure required to Read More...

Protein Characterization Laboratory (PCL) offers various technologies to CCR investigators to characterize proteins and metabolites. The laboratory develops and applies state-of-the-art analytical technologies, primarily mass spectrometry, liquid chromatography, and Surface Plasmon Resonance (SPR), to advance Read More...

The facilities at AIM are available for use by the entire NIH intramural research community. While we welcome users with any size imaging project, AIM specializes in large, yearlong (or longer), collaborative research efforts with Read More...

[tabby title="Home"] About NICE-NIH Intramural CryoEM Consortium  NIH Intramural CryoEM Consortium (NICE) serves intramural investigators in all NIH IC’s. NICE provides access to state-of-the-art Titan Krios cryo-electron microscopes for atomic-resolution structure determination of Read More...

Anaconda ( https://www.anaconda.com/ ) is a package manager and distributor for a wide array of data science software. Package managers are ideal for scientists who conduct analysis on a personal computer as they eliminate Read More...

04/16/2025 - Updated Location: ATRF, Frederick MD, Main Auditorium What to bring:  Laptop capable of connecting to internet via NIH wifi For questions or to register, please contact Amy Stonelake ( amy.stonelake@nih.gov ) Read More...

Long read sequencing was recently named 2022’s method of the year by Nature Methods . Long read sequencing technologies, those that generate sequence reads with lengths of 10s of kilobases or longer have several advantages over Read More...

Recently, the NIH HPC Team has provided on demand access to HPC resources via web browser through integration of Open OnDemand , an open source project supporting "nearly 400 HPC centers around the world" . This Read More...

Congratulations, your experiments have been completed and you have a large amount of data. Now, it’s time to analyze these data. But where do you begin? How can you gain the most meaning from Read More...

This lesson provides an introduction to R in the context of single cell RNA-Seq analysis with Seurat. Learning Objectives Learn about options for analyzing your scRNA-Seq data. Learn about resources for learning R programming. Learn Read More...

04/01/2024 - Embark on a journey of visionary insights! Join us for the launch of the NEI Informatics & Data-Driven Insights: Seminars & Dialogue Opportunities for Vision Health series, hosted by the National Eye Read More...

03/22/2024 - This 3-hour seminar is tailored for biologists, data analysts, and researchers who are eager to dive into the essentials of computational flow cytometry analysis using R. Flow cytometry is a crucial technique in cell Read More...

Accessing Partek Flow at NIH and tips for data transfer Learning objectives After consulting this guide, participants will Know how to access Partek Flow at NIH. Be able to transfer data from NCI CCR Sequencing Read More...

Accessing Partek Flow at NIH and tips for data transfer Learning objectives Instructions for accessing Partek Flow NCI researchers can find instructions for accessing Partek Flow at https://bioinformatics.ccr.cancer.gov/btep/partek-flow-bulk-and-single-cell-rna-seq-data-analysis/ . But Read More...