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Search Results for: frederick

Total Results Found: 167

Total Results Found: 167

Frederick Sequencing and Genomic Core (FSGC)
Frederick , MD

Core Facility

The Frederick Sequencing and Genomics Core (FSGC) was established through the integration and consolidation of the former Sequencing Facility (SF) and the Genomics Technology Laboratory (GTL). The new FSGC eliminates redundancy and provides cutting edge Read More...

NCI at Frederick Central Repository
Frederick, MD

Repositories

The Central Repository provides the research community at the NCI with various cryogenic services, including low-temperature storage from +4° C to -196° C, controlled-rate freezing, computerized inventory and distribution of samples. The Central Repository is operated Read More...

NCI CCR-Frederick Flow Cytometry Core Facility
Frederick, MD

Core Facility

The CCR-Frederick Flow Cytometry Core Facility provides research support to the Frederick-CCR community, including cytometry analysis and sorting services, instrument maintenance, new user training, and technical consultation. Typical Assays Performed by Core Instruments Immunophenotyping of Read More...

NCI Advanced Biomedical Computational Science (ABCS)
Frederick, MD

Core Facility

The Advanced Biomedical Computational Sciences (ABCS) group provides technology development, scientific consultation, collaboration and training, research, software development, and high-performance computing support. ABCS encompasses specialized groups focusing on machine learning applied to the interpretation of 2 Read More...

NCI Clinical Support Laboratory: Flow Cytometry Section
Frederick, MD

Core Facility

Clinical Support Laboratory – Flow Cytometry Section is a laboratory specializing in providing immunophenotyping support of NCI intramural clinical trials, though assessments may also be performed using cells from Non-human primates and other species. The CSL Read More...

Statistical Support at ABCS
Frederick, MD

Core Facility

The centrally funded Statistics team within the Advanced Biomedical Computational Science group at the Frederick National Lab provides statistical consultation and data analysis support for NCI laboratories. We have broad-range expertise in biomedically relevant areas Read More...

BRB Preclinical Biologics Repository
Frederick, MD

Repositories

The BRB Preclinical Biologics Repository is a central repository that supplies reagents to the broad research community. This NCI-sponsored repository is managed by NCI's Biological Resources Branch (BRB) in the Development Therapeutics Program (DTP) of Read More...

Scientific Publications, Graphics & Media (SPGM)
Frederick, MD

Core Facility

Our mission is to help both scientists and non-scientists at the Frederick National Laboratory communicate more effectively. We aim to provide our customers with maximum convenience and unique value. Established Technologies Scientific Illustration SPGM illustrators Read More...

CCR Electron Microscopy Core (EMC)
Frederick, MD

Core Facility

The Electron Microscopy Core (EMC), formerly known as Electron Microscopy Lab (EML),  offers investigators access to unique expertise and EM technologies that allow CCR Investigators to explore new avenues of research in order to enhance Read More...

CCR Optical Microscopy and Analysis Core (OMAC)
Frederick, MD

Core Facility

The Optical Microscopy Analysis Core (OMAC), formerly known as the Optical Microscopy Analysis Lab (OMAL),  focuses its research and development activities to quantitatively understand the molecular basis of three-dimensional (3D) cell organization, motility, invasion, and Read More...

NCI LASP Animal Research Technology Support (ARTS)
Frederick, MD

Core Facility

NCI LASP Animal Research Technology Support (ARTS) provides customized technical support for basic and translational animal-based research to the scientific community. We offer a wide array of services ranging from expert colony management to the Read More...

Bioinformatics Resources

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Discover expert help with analysis, processing applications, and licensed software packages.

CCR Volume Electron Microscopy Core(CVEMC)
Frederick, MD

Collaborative

CCR VOLUME Electron Microscopy Core (CVEMC),  formerly known as volume Electron Microscopy (vEM), aims to develop new techniques in volume electron microscopy (vEM) and, in collaboration with CCR Investigators, apply these techniques to research cell Read More...

Biological Products Core (AIDS and Cancer Virus Program)
Frederick, Maryland

Core Facility

Repositories

The Biological Products Core provides the AIDS research community with high-quality purified preparations of various strains of Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV), economically prepared by leveraging the economy of scale. Materials Read More...

Small STARS Submission Instructions

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Small STARS can be used to request supplemental funding to offset exceptional costs (e.g., core or vendor services or specialized reagents).  All requests must be approved for funding before work can commence. Provides 50% cost Read More...

Clinical Support Laboratory
Frederick, MD

Core Facility

The Clinical Support Laboratory offers processing, tracking, and testing of a broad range of clinical samples. Support can begin at the early stages of clinical trial development to aid in developing a comprehensive strategy for Read More...

Antibody Characterization Laboratory (ACL)
Frederick, MD

Collaborative

The Antibody Characterization Laboratory (ACL) is the laboratory responsible for the development of well-characterized monoclonal antibody reagents. The NCI’s Office of Cancer Clinical Proteomics Research funds ACL as a resource to the entire cancer Read More...

NCI LASP Gnotobiotics Facility (GF)
Frederick, MD

Core Facility

The Laboratory Animal Sciences Program (LASP) of the Frederick National Laboratory operates a Gnotobiotics Facility (GF) to support research focused on the role of microbiota in cancer inflammation, pathogenesis, and treatment response. The GF can Read More...

NCI Center for Structural Biology: Crystallization Facility
Frederick, MD

Collaborative

The Crystallization Facility provides an automated environment for setting up crystallization experiments in a high-throughput format, storing the resulting plates under controlled conditions, and monitoring the status of prepared droplets remotely. The Facility is in Read More...

The Cancer Imaging Archive (TCIA)
Frederick, MD

Repositories

TCIA is a service which de-identifies and publishes medical images of cancer for download. New data proposals are reviewed by an Advisory Group on a quarterly basis. The data are organized as “collections”; typically, patients’ Read More...

NCI Synthetic Biologics Core
Frederick, MD

Core Facility

The research conducted within the Synthetic Biologics Core (SBC) Facility has a dual role: Generate chemical biology tools and drug candidates for molecular targets identified by NCI research groups, Develop novel effective methods and tools Read More...

June 2024 Newsletter

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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx Program Manager The CREx Team is happy to announce Deepika Velampati as the new CREx Program Read More...

NCI LASP Small Animal Imaging Program (SAIP)
Frederick, MD

Core Facility

The function of the SAIP is to collaborate with NCI investigators in the development of mouse models, new molecular imaging probes for early detection and therapy, monitor tumors in vivo, and perform drug efficacy studies Read More...

DCTD Tumor Repository
Frederick, MD

Repositories

NCI maintains a low temperature repository of implantable in vivo-derived tumors and in vitro-established tumor cell lines from various species, which are available to qualified investigators as a service to the cancer research community. The Read More...

May 2024 Newsletter

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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Intramural Core Resources NHGRI Flow Cytometry Core The Core performs high quality single cell analysis through the Read More...

July 2024 Newsletter

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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx User Survey The CREx Team is carrying out a CREx User Survey. We would greatly appreciate Read More...

NCI LASP Animal Diagnostic Laboratory and Genotyping Core (ADL)
Frederick, MD

Core Facility

The Animal Diagnostic Laboratory (ADL) provides a full range of diagnostic capabilities, including microbiological cultures on various culture medium, microscopic screening for parasites such as mites and pinworms, molecular detection of pathogens, serological evaluation of Read More...

Chemical Biology Laboratory (CBL): Chemical Synthesis Group
Frederick, MD

Collaborative

The Chemical Synthesis Group is a component of the Chemical Biology Laboratory. This facility provides synthetic chemistry resources and expertise to the NCI Intramural community.The facility’s capabilities include: Providing expertise, consultation, and experience Read More...

Molecular Targets Program (MTP)
Frederick, MD

Collaborative

The Molecular Targets Program (MTP) is an organizational entity within the Center for Cancer Research (CCR) at NCI. The MTP provides the focus and infrastructure to enable CCR tenured and tenure-track Principal Investigators to initiate Read More...

CLIA Molecular Diagnostics Laboratory
Frederick, Maryland

Core Facility

CLIA-Certified Technologies Offered: Fragment Analysis for Micro-satellite Instability Detection, Pharmacoscan Array for Pharmacogenomics, Mutation Detection for PCR and Sanger Sequencing, DNA extraction from whole blood, saliva, FFPE tissues, buccal swabs, nails, hair, PBMCs, buffy coats, Read More...

NCI LASP Genome Modification Core (GMC)
Frederick, MD

Core Facility

NCI LASP Genome Modification Core (GMC) is a CCR-dedicated facility that provides advice, training, and reagents to NCI scientists seeking to utilize CRISPR and other nucleases to generate genome modifications in primary cells, cell lines, Read More...

Biopharmaceutical Development Program (BDP)
Frederick, MD

Collaborative

The Biopharmaceutical Development Program (BDP) provides resources for the development of investigational biological agents. The BDP supports feasibility through development and Phase I/II cGMP manufacturing plus regulatory documentation. The BDP was established in 1993. We Read More...

CCR Single Cell and Spatial Core (SCSC)
Bethesda, MD

Core Facility

The rapid advancement of single-cell technology has provided new powerful tools to answer many biological questions, such as identifying new or rare cell populations and characterizing the complexities of tumor heterogeneity. Realizing the great potential Read More...

NCI Center for Structural Biology: Protein Technology Core
Frederick, MD

Collaborative

The primary objective of the Protein Technology Core (PTC) is to establish an experimental screening pipeline for single-domain antibodies termed nanobodies. Nanobodies are antibody fragments consisting of a single monomeric variable antibody domain. The PTC, Read More...

DTP Natural Products Repository
Frederick, MD

Repositories

DTP’s Natural Products Repository is the world’s largest storehouse of natural products. It houses close to >200,000 extracts from samples of more than 70,000 plants and >20,000 marine organisms collected from more than 29 countries, plus extracts Read More...

Clinical Support Laboratory –Cellular Immunology
Frederick, MD

Core Facility

Clinical Support Laboratory – Cellular Immunology offers a spectrum of bioassays to assess cellular responses to antigens and mitogens including ELISPOT, cytotoxicity assays, and proliferation assays. Established Technologies Elispot Assays, Dual or Triple Color Fluorospot Assays, Read More...

Nanotechnology Characterization Lab
Frederick, MD

Collaborative

NCI established the Nanotechnology Characterization Laboratory (NCL) to support the extramural research community to accelerate the progress of nanomedicine by providing preclinical characterization and safety testing of nanoparticles. It is a collaborative effort between NCI, Read More...

June 2021

Web Page

CREx News & Updates June 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGHLIGHTS Visit here to learn about services from Read More...

CCR Protein and Metabolite Characterization Core (PMCC)
Frederick, MD

Core Facility

Protein and Metabolite Characterization Core (PMCC), formerly known as the Protein Characterization Lab (PCL),  offers various technologies to CCR investigators to characterize proteins and metabolites. The core develops and applies state-of-the-art analytical technologies, primarily mass Read More...

NCI Medicinal Chemistry Accelerator (MCA)
Frederick, MD

Collaborative

The Medicinal Chemistry Accelerator (MCA) is a collaborative CCR resource that supports investigators in developing small molecule inhibitors for anticancer drug candidates. While CCR and NCATS have infrastructure to identify initial “hits” through high-throughput screening, Read More...

NCI Molecular Cytogenetics Core Facility
Frederick, MD

Core Facility

Molecular Cytogenetics Core Facility facilitates the assessment of structural and numerical genomic changes in pre-cancer and cancer research models. This core provides comprehensive support for the cytogenetic analysis of cells from human and research animal Read More...

All Scientific Resources

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Cores & Facilities From centralized laboratories to collaborative resources and technologies available to CCR Investigators. NCI Cores Centralized laboratories providing broad access to cutting-edge technologies and specialized expertise. Browse NCI Cores Collaborative Resources are technologies and Read More...

Center for Structural Biology: Biophysics Resource
Frederick, MD

Core Facility

The Biophysics Resource (BR) was established in January 2001. Our mission is to provide CCR investigators with access to both the latest instrumentation and expertise in characterizing the biophysical aspects of systems under structural investigation. The Read More...

CCR Collaborative Bioinformatics Resource (CCBR)
Bethesda, MD

Collaborative

The CCR Collaborative Bioinformatics Resource (CCBR) is a centrally funded resource group which provides a mechanism for CCR researchers to obtain many different types of bioinformatics assistance to further their research goals. The group has Read More...

September 2021

Web Page

CREx News & Updates September 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGLIGHTS Learn more about services from the CCR Read More...

NCI SAXS Facility
Frederick, MD

Collaborative

In order to meet increasing demands from both NIH intramural and extramural communities for access to a small angle X-ray scattering (SAXS) resource, the Center for Cancer Research (CCR) under the leadership of Drs. Jeffrey Read More...

STARS Request

Web Page

Supplemental Technology Award Review System (STARS) Overview STARS Request Form STARS System The Supplemental Technology Award Review System (STARS) is a web-based interface for submission and review of S&S supplement requests by CCR Read More...

NCI LASP Mouse Modeling & Cryopreservation (MMC)
Frederick, MD

Core Facility

Repositories

Mouse models of human cancer have had a profound impact on our current understanding of the mechanisms of tumorigenesis and the pathways regulated by cancer-related genes. These models hold the promise of serving as critical Read More...

Technology Video Library

Web Page

The OSTR offers cutting-edge technology platforms to the CCR scientific community through centralized facilities. The videos accessed through this page are designed to introduce the various scientific methodologies OSTR makes available through the cores on Read More...

Partek Genomics Suite Workshop at NCI-Frederick

Web Page

Bioinformatics

04/26/2017 - The CCR Bioinformatics Training and Education Program (BTEP) is pleased to organize a workshop on Partek Genomics Suite for scientists at NCI-Frederick. Partek ® Genomics Suite ® is a versatile scientific software with an easy-to-use graphical Read More...

Partek Flow Workshop for CCR Scientists at NCI-Frederick

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Bioinformatics

03/29/2017 - The CCR Bioinformatics Training and Education Program (BTEP) is pleased to organize a workshop on Partek Flow for scientists at NCI-Frederick . Partek Flow software is designed specifically for the analysis needs of next generation Read More...

Introduction to Next-Generation Sequencing Analysis on FRCE

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Bioinformatics

10/24/2023 - In this session, we will provide an overview of the Next-Generation Sequencing (NGS) capabilities and applications. We will present the workflows and analyses for Illumina short-read, PacBio, and Oxford Nanopore long-read sequencing on Frederick Read More...

NCI and NIH Data Science Resources

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Bioinformatics

03/08/2022 - Are you interested in growing your data science skills or connecting with like-minded practitioners at NCI? Join us on  March 8, 3:00 pm – 4:00 pm ET  for a seminar on data science resources available to NCI staff!  Read More...

HPC FRCE User Group: Open OnDemand

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Bioinformatics

06/24/2025 - Thi year the Frederick Re earch Compute Environment (FRCE) i expanding it outreach. Our fir t new feature i a web-ba ed tool that will allow you to ea ily run graphical application on Read More...

Clustering with R and RStudio

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Bioinformatics

03/12/2025 - Clustering is one of the fundamental unsupervised machine learning algorithms. It is often used to group quantitative proteomic or RNAseq expression data to suggest sub-types of a particular cancer. This presentation covers building a Read More...

Survival Analysis in R Using the survival Package

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Bioinformatics

01/15/2025 - This session of the BTEP Coding Club will demonstrate how to use the R package “survival” to conduct a survival analysis of an example dataset.  Senior Programmer and Analyst, Duncan Donohue, PhD, will cover Read More...

Introduction to Survival Analysis

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Bioinformatics

01/14/2025 - In this talk, we will cover the basics of survival analysis as a statistical methodology developed for censored data. Special emphasis will be on visualizing survival data, comparing survival-time distributions for subject groups, and Read More...

Statistical Considerations for Animal Model Experiments

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Bioinformatics

11/12/2024 - We will discuss statistical considerations in planning, executing, and interpreting experiments using animals. Topics will include interpreting minimally powered pilot studies, dealing with complex time series, and maximizing knowledge gain from limited resources. This Read More...

Introduction to linear mixed-effects modeling

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Bioinformatics

08/13/2024 - This session will cover the basics of linear mixed-effects modeling as a method of regression analysis for clustered data. Special emphasis will be on the ideas behind random-intercepts and random-slopes modeling, and the discussion Read More...

Introduction to Statistical Resampling Methods

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Bioinformatics

06/11/2024 - This talk will cover the basics of statistical resampling methods such as bootstrap, Monte Carlo, and permutations for estimating parameters and testing hypotheses.  We will discuss when you might want to use Read More...

Effect Size, p-value, and Accuracy

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Bioinformatics

05/14/2024 - This presentation will explain the difference between the mean and standard deviation of a set of values and the standard error of the mean. The parameters involved in comparing two normally distributed populations relative Read More...

Organizing and documenting NGS pipelines on GitHub

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Bioinformatics

04/16/2024 - GitHub is a powerful platform for tracking, sharing, and collaborating on software projects of all kinds. Whether you’re a bioinformatics analyst, a software engineer, or a biologist who sometimes codes, GitHub Read More...

Parametric vs. non-parametric statistics

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Bioinformatics

04/09/2024 - In this talk, we will cover what differentiates parametric and non-parametric statistics, tests/methods of both types for different data scenarios, when to use one vs. the other, and tradeoffs/pitfalls of each. This Read More...

Protein Structure Prediction on FRCE

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Bioinformatics

11/28/2023 - Recent advances in protein structure prediction methods such as AlphaFold2 and ESMFold has enabled protein structure prediction to achieve experimental accuracy in certain cases. In this talk, we will discuss the advantages and limitations Read More...

Batch Correction and Sample Randomization

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Bioinformatics

09/12/2023 - In this talk we will discuss how and why to minimize and correct for batch effects in our experiments. We will cover appropriate sample randomization and several computational methods to help uncover and mitigate Read More...

R or Python, Which Should I Learn?

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Bioinformatics

10/28/2021 - Please join us for a discussion followed by question and answer session on the topic of “R or Python, Which Should I Learn?”. We will be joined by Andrew Weisman of the Frederick National Read More...

Hyperparameter Optimization Using CANDLE on Biowulf

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Bioinformatics

01/19/2021 - Overview Are you interested in improving your machine or deep learning models? You often cannot be sure you've developed the best model without performing hyperparameter optimization. In this talk, we will explain what Read More...

Introduction to R markdown for Automated Reports

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Bioinformatics

10/20/2020 - Register R markdown offers tools to generate and update reports automatically—including figures, tables, mathematical equations and code. Instead of copying tables and figures into another document, you can update reports quickly and easily Read More...

Cancer Type/Site Classification Using Deep Learning

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Bioinformatics

09/22/2020 - [one_half] This two-part workshop will demonstrate how deep learning can be used to classify different types of cancer. Part I will focus on data preparation, starting with genomic data. Part II will demonstrate Read More...

CCR Sequencing Cores

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Bioinformatics

There are two main Core facilities providing DNA sequencing services for CCR scientists. CCR Sequencing Facility Located at the ATRF in Frederick provides production quality high throughput sequencing service to the CCR community.  Their service Read More...

Workshop on Analysis of ChIP-Seq Data

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Bioinformatics

05/16/2016 - This 2-day course, which includes both lecture and hands-on components, will teach the basic concepts and practical aspects of ChIP-Seq Data Analysis. There will also be a talk on ENCODE and a comprehensive discussion Read More...

Image Gallery

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Confocal

Confocal Microscope Image of Fixed Mouse Embryonic Fibroblast (MEF) Cells Actin proteins (stained red) and Tubulin proteins (stained green) are involved in a number of cellular process such as cell motility, cell division and maintenance Read More...

Resources

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Bioinformatics

BTEP strives to maintain links to resources that should be of interest to CCR Bioinformatics Community.  Some of the resources to will be accessible through more than one of these lists, but since the lists Read More...

The Advanced Biomedical Computational Science (ABCS) Group

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Bioinformatics

The Advanced Biomedical Computational Science (ABCS) group focuses on applications of bioinformatics, computational and data science, and artificial intelligence to support NCI researchers. ABCS provides: • Subject matter expertise in genomics, proteomics, and imaging. • Machine learning/ Read More...

Python: Variable Scope, Programming Style, Wrap-Up

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Bioinformatics

06/14/2022 - Python is one of the preferred programming languages for scientists to solve a wide variety of biological problems. We find that many scientists who come to Software Carpentry workshops use Python and want to Read More...

Python: Plotting 2, Lists, For Loops

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Bioinformatics

05/31/2022 - Python is one of the preferred programming languages for scientists to solve a wide variety of biological problems. We find that many scientists who come to Software Carpentry workshops use Python and want to Read More...

Variable Scope, Programming Style, Wrap-Up

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Bioinformatics

05/25/2021 - Registration is required. Register at this link . Python is a good programming language for scientists to solve a wide variety of biological problems. We find that many scientists who come to Software Carpentry workshops Read More...

Plotting 2, Lists, For Loops

Web Page

Bioinformatics

05/11/2021 - Registration is required. Register at this link . Python is a good programming language for scientists to solve a wide variety of biological problems. We find that many scientists who come to Software Carpentry workshops Read More...

NIH Virtual Workshop on Ultra-Large Chemistry Databases

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Bioinformatics

12/01/2020 - Please Register to join us for a virtual workshop focused on defining the major challenges and promising new approaches for creating, curating, integrating, and querying across ultra-large chemistry databases. This event is a Three Read More...

Bioinformatics Workshop: Single Cell RNA-Seq Analysis

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Bioinformatics

05/20/2020 - Advances in technology have reduced the cost of single cell sequencing, opening the doors to many new areas of study including transcriptome, DNA genomics, epigenomics and microbial systems. This workshop, provided by experts from Read More...

Single Cell RNA-Seq (WebEx Seminar)

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Bioinformatics

04/25/2018 - Join us for a seminar/webinar session where Partek Specialist will show you how to analyze your Single Cell RNA-Seq data in an intuitive, interactive and powerful way using Partek Flow. The solution simplifies Read More...

Informational Session on BTEP

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Bioinformatics

03/29/2017 - The CCR Bioinformatics Training and Education Program (BTEP) is excited to arrange its inaugural informational presentation for the CCR scientific community at NCI-Frederick. Date: Wednesday, March 29, 2017 Time: 11:00 am - 12:00 pm Location: ATRF Room E-1106 Read More...

BTEP Workshop on NCBI Resources for CCR Scientists

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Bioinformatics

06/06/2016 - The 'NCBI Resources for CCR Scientists' workshop, on June 6 and June 8, 2016, will focus on teaching a wide range of resources developed within NCBI that are relevant for CCR scientists. It will include both hands-on Read More...

Media

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CRTP

No summary available.

Contact Us

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Confocal

Gianluca Pegoraro, PhD gianluca.pegoraro@nih.gov Facility Head 240-760-6696 Bldg. 41, Room B909 Dr. Pegoraro received his Ph.D. in Molecular Genetics from the International School of Superior Studies in Trieste, Italy in 2004. After Read More...

Personnel

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Confocal

Gianluca Pegoraro, PhD gianluca.pegoraro@nih.gov Facility Head 240-760-6696 Bldg. 41, Room B909 Dr. Pegoraro received his Ph.D. in Molecular Genetics from the International School of Superior Studies in Trieste, Italy in 2004. After Read More...

Training & Support

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Confocal

Training We recommend that users become familiar with the principals of fluorescence labeling and optical microscopy before arranging for training. We recommend the following sites for learning about microscopy: Introductions to Fluorescence Microscopy Fluorescence Labeling Read More...

FAQ

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CRTP

How do I determine which EM technique should be used for my research? Schedule a free consultation with the Head of EMC, Dr. Ru-ching Hsia, to discuss the aim of your research project. Dr.& Read More...

Personnel

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CRTP

No summary available.

FAQ

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CRTP

No summary available.

Home

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CRTP

No summary available.