Frederick , MD
Core Facility
The Frederick Sequencing and Genomics Core (FSGC) was established through the integration and consolidation of the former Sequencing Facility (SF) and the Genomics Technology Laboratory (GTL). The new FSGC eliminates redundancy and provides cutting edge Read More...
Frederick, MD
Repositories
The Central Repository provides the research community at the NCI with various cryogenic services, including low-temperature storage from +4° C to -196° C, controlled-rate freezing, computerized inventory and distribution of samples. The Central Repository is operated Read More...
Frederick, MD
Core Facility
The CCR-Frederick Flow Cytometry Core Facility provides research support to the Frederick-CCR community, including cytometry analysis and sorting services, instrument maintenance, new user training, and technical consultation. Typical Assays Performed by Core Instruments Immunophenotyping of Read More...
Frederick, MD
Core Facility
The FNLCR Molecular Histopathology Laboratory (MHL) provides comprehensive veterinary pathology support for animal health monitoring, biomarker discovery and validation, drug development, genomics, and proteomics on a cost recovered basis. The MHL is organized into multiple Read More...
Frederick, MD
Core Facility
The Advanced Biomedical Computational Sciences (ABCS) group provides technology development, scientific consultation, collaboration and training, research, software development, and high-performance computing support. ABCS encompasses specialized groups focusing on machine learning applied to the interpretation of 2 Read More...
Frederick, MD
Core Facility
Clinical Support Laboratory – Flow Cytometry Section is a laboratory specializing in providing immunophenotyping support of NCI intramural clinical trials, though assessments may also be performed using cells from Non-human primates and other species. The CSL Read More...
Frederick, MD
Core Facility
The centrally funded Statistics team within the Advanced Biomedical Computational Science group at the Frederick National Lab provides statistical consultation and data analysis support for NCI laboratories. We have broad-range expertise in biomedically relevant areas Read More...
Frederick, MD
Repositories
The BRB Preclinical Biologics Repository is a central repository that supplies reagents to the broad research community. This NCI-sponsored repository is managed by NCI's Biological Resources Branch (BRB) in the Development Therapeutics Program (DTP) of Read More...
Frederick, MD
Core Facility
Our mission is to help both scientists and non-scientists at the Frederick National Laboratory communicate more effectively. We aim to provide our customers with maximum convenience and unique value. Established Technologies Scientific Illustration SPGM illustrators Read More...
Frederick, MD
Core Facility
The Electron Microscopy Core (EMC), formerly known as Electron Microscopy Lab (EML), offers investigators access to unique expertise and EM technologies that allow CCR Investigators to explore new avenues of research in order to enhance Read More...
Frederick, MD
Core Facility
The Optical Microscopy Analysis Core (OMAC), formerly known as the Optical Microscopy Analysis Lab (OMAL), focuses its research and development activities to quantitatively understand the molecular basis of three-dimensional (3D) cell organization, motility, invasion, and Read More...
Frederick, MD
Core Facility
NCI LASP Animal Research Technology Support (ARTS) provides customized technical support for basic and translational animal-based research to the scientific community. We offer a wide array of services ranging from expert colony management to the Read More...
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Discover expert help with analysis, processing applications, and licensed software packages.
Frederick, MD
Collaborative
The NMR Facility for Biological Research operates six NMR spectrometers with proton resonance frequencies from 850 to 500 MHz. Three of the highest field spectrometers (850, 700, 600) are equipped with higher sensitivity cryoprobes optimized for high-resolution multi-dimensional and relaxation Read More...
Frederick, MD
Collaborative
CCR VOLUME Electron Microscopy Core (CVEMC), formerly known as volume Electron Microscopy (vEM), aims to develop new techniques in volume electron microscopy (vEM) and, in collaboration with CCR Investigators, apply these techniques to research cell Read More...
Frederick, Maryland
Core Facility
Repositories
The Biological Products Core provides the AIDS research community with high-quality purified preparations of various strains of Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV), economically prepared by leveraging the economy of scale. Materials Read More...
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Small STARS can be used to request supplemental funding to offset exceptional costs (e.g., core or vendor services or specialized reagents). All requests must be approved for funding before work can commence. Provides 50% cost Read More...
Frederick, MD
Core Facility
The Clinical Support Laboratory offers processing, tracking, and testing of a broad range of clinical samples. Support can begin at the early stages of clinical trial development to aid in developing a comprehensive strategy for Read More...
Frederick, MD
Collaborative
The Antibody Characterization Laboratory (ACL) is the laboratory responsible for the development of well-characterized monoclonal antibody reagents. The NCI’s Office of Cancer Clinical Proteomics Research funds ACL as a resource to the entire cancer Read More...
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Protein/Protein Interaction Database Through a license agreement with Elsevier, the CCR community has access to the largest Y2H data set available in the world (CCR Database of Antibodies and Protein Interactions, C-DAPI). This Read More...
Frederick, MD
Core Facility
The Laboratory Animal Sciences Program (LASP) of the Frederick National Laboratory operates a Gnotobiotics Facility (GF) to support research focused on the role of microbiota in cancer inflammation, pathogenesis, and treatment response. The GF can Read More...
Frederick, MD
Collaborative
The Crystallization Facility provides an automated environment for setting up crystallization experiments in a high-throughput format, storing the resulting plates under controlled conditions, and monitoring the status of prepared droplets remotely. The Facility is in Read More...
Frederick, MD
Repositories
TCIA is a service which de-identifies and publishes medical images of cancer for download. New data proposals are reviewed by an Advisory Group on a quarterly basis. The data are organized as “collections”; typically, patients’ Read More...
Frederick, Maryland
Collaborative
Bruker AVANCE 400 and 500 MHz NMR instruments. Helium Cryoprobe technology on the 500 MHz machine for added sensitivity, especially for Carbon-13 spectra. Access to a second 500 MHz instrument with Prodigy Liquid Nitrogen-cooled cryoprobe. User Accounts can be Read More...
Frederick, MD
Core Facility
The research conducted within the Synthetic Biologics Core (SBC) Facility has a dual role: Generate chemical biology tools and drug candidates for molecular targets identified by NCI research groups, Develop novel effective methods and tools Read More...
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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx Program Manager The CREx Team is happy to announce Deepika Velampati as the new CREx Program Read More...
Frederick, MD
Core Facility
The function of the SAIP is to collaborate with NCI investigators in the development of mouse models, new molecular imaging probes for early detection and therapy, monitor tumors in vivo, and perform drug efficacy studies Read More...
Frederick, MD
Repositories
NCI maintains a low temperature repository of implantable in vivo-derived tumors and in vitro-established tumor cell lines from various species, which are available to qualified investigators as a service to the cancer research community. The Read More...
Web Page
CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Intramural Core Resources NHGRI Flow Cytometry Core The Core performs high quality single cell analysis through the Read More...
Web Page
CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx User Survey The CREx Team is carrying out a CREx User Survey. We would greatly appreciate Read More...
Frederick, MD
Core Facility
The Animal Diagnostic Laboratory (ADL) provides a full range of diagnostic capabilities, including microbiological cultures on various culture medium, microscopic screening for parasites such as mites and pinworms, molecular detection of pathogens, serological evaluation of Read More...
Frederick, MD
Collaborative
The Chemical Synthesis Group is a component of the Chemical Biology Laboratory. This facility provides synthetic chemistry resources and expertise to the NCI Intramural community.The facility’s capabilities include: Providing expertise, consultation, and experience Read More...
Frederick, MD
Collaborative
The Molecular Targets Program (MTP) is an organizational entity within the Center for Cancer Research (CCR) at NCI. The MTP provides the focus and infrastructure to enable CCR tenured and tenure-track Principal Investigators to initiate Read More...
Frederick, Maryland
Core Facility
CLIA-Certified Technologies Offered: Fragment Analysis for Micro-satellite Instability Detection, Pharmacoscan Array for Pharmacogenomics, Mutation Detection for PCR and Sanger Sequencing, DNA extraction from whole blood, saliva, FFPE tissues, buccal swabs, nails, hair, PBMCs, buffy coats, Read More...
Frederick, MD
Core Facility
NCI LASP Genome Modification Core (GMC) is a CCR-dedicated facility that provides advice, training, and reagents to NCI scientists seeking to utilize CRISPR and other nucleases to generate genome modifications in primary cells, cell lines, Read More...
Frederick, MD
Collaborative
The Biopharmaceutical Development Program (BDP) provides resources for the development of investigational biological agents. The BDP supports feasibility through development and Phase I/II cGMP manufacturing plus regulatory documentation. The BDP was established in 1993. We Read More...
Bethesda, MD
Core Facility
The Blood Processing Core monitors viral load in patients with HIV and performs sequential studies using samples obtained from patients with cancer, AIDS, chronic granulomatous disease, or other diseases associated with immunologic dysfunction. The core Read More...
Bethesda, MD
Core Facility
The rapid advancement of single-cell technology has provided new powerful tools to answer many biological questions, such as identifying new or rare cell populations and characterizing the complexities of tumor heterogeneity. Realizing the great potential Read More...
Frederick, MD
Collaborative
The primary objective of the Protein Technology Core (PTC) is to establish an experimental screening pipeline for single-domain antibodies termed nanobodies. Nanobodies are antibody fragments consisting of a single monomeric variable antibody domain. The PTC, Read More...
Frederick, MD
Repositories
DTP’s Natural Products Repository is the world’s largest storehouse of natural products. It houses close to >200,000 extracts from samples of more than 70,000 plants and >20,000 marine organisms collected from more than 29 countries, plus extracts Read More...
Frederick, MD
Core Facility
Clinical Support Laboratory – Cellular Immunology offers a spectrum of bioassays to assess cellular responses to antigens and mitogens including ELISPOT, cytotoxicity assays, and proliferation assays. Established Technologies Elispot Assays, Dual or Triple Color Fluorospot Assays, Read More...
Frederick, MD
Collaborative
NCI established the Nanotechnology Characterization Laboratory (NCL) to support the extramural research community to accelerate the progress of nanomedicine by providing preclinical characterization and safety testing of nanoparticles. It is a collaborative effort between NCI, Read More...
Web Page
CREx News & Updates June 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGHLIGHTS Visit here to learn about services from Read More...
Frederick, MD
Core Facility
Protein and Metabolite Characterization Core (PMCC), formerly known as the Protein Characterization Lab (PCL), offers various technologies to CCR investigators to characterize proteins and metabolites. The core develops and applies state-of-the-art analytical technologies, primarily mass Read More...
Frederick, MD
Collaborative
The Medicinal Chemistry Accelerator (MCA) is a collaborative CCR resource that supports investigators in developing small molecule inhibitors for anticancer drug candidates. While CCR and NCATS have infrastructure to identify initial “hits” through high-throughput screening, Read More...
Frederick, MD
Core Facility
Molecular Cytogenetics Core Facility facilitates the assessment of structural and numerical genomic changes in pre-cancer and cancer research models. This core provides comprehensive support for the cytogenetic analysis of cells from human and research animal Read More...
Web Page
Cores & Facilities From centralized laboratories to collaborative resources and technologies available to CCR Investigators. NCI Cores Centralized laboratories providing broad access to cutting-edge technologies and specialized expertise. Browse NCI Cores Collaborative Resources are technologies and Read More...
Frederick, MD
Core Facility
The Biophysics Resource (BR) was established in January 2001. Our mission is to provide CCR investigators with access to both the latest instrumentation and expertise in characterizing the biophysical aspects of systems under structural investigation. The Read More...
Bethesda, MD
Collaborative
The CCR Collaborative Bioinformatics Resource (CCBR) is a centrally funded resource group which provides a mechanism for CCR researchers to obtain many different types of bioinformatics assistance to further their research goals. The group has Read More...
Web Page
CREx News & Updates September 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGLIGHTS Learn more about services from the CCR Read More...
Frederick, MD
Collaborative
In order to meet increasing demands from both NIH intramural and extramural communities for access to a small angle X-ray scattering (SAXS) resource, the Center for Cancer Research (CCR) under the leadership of Drs. Jeffrey Read More...
Web Page
Supplemental Technology Award Review System (STARS) Overview STARS Request Form STARS System The Supplemental Technology Award Review System (STARS) is a web-based interface for submission and review of S&S supplement requests by CCR Read More...
Frederick, MD
Core Facility
Repositories
Mouse models of human cancer have had a profound impact on our current understanding of the mechanisms of tumorigenesis and the pathways regulated by cancer-related genes. These models hold the promise of serving as critical Read More...
Web Page
The OSTR offers cutting-edge technology platforms to the CCR scientific community through centralized facilities. The videos accessed through this page are designed to introduce the various scientific methodologies OSTR makes available through the cores on Read More...
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Bioinformatics
05/28/2024 - Frederick Research Computing Environment (FRCE) and Computational Sciences Series In this session, we will explore how machine learning can be used to analyze whole slide pathological images (WSIs). We will showcase how to utilize Read More...
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Bioinformatics
08/22/2023 - In this session, we will discuss conceptual overview of a computing cluster, how to get access to the NCI cluster in Frederick (FRCE) and how to connect and run basic programs. We will also Read More...
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Bioinformatics
04/16/2025 - Updated Location: ATRF, Frederick MD, Main Auditorium What to bring: Laptop capable of connecting to internet via NIH wifi For questions or to register, please contact Amy Stonelake ( amy.stonelake@nih.gov ) Read More...
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Bioinformatics
08/28/2019 - THIS EVENT HAS BEEN CANCELLED Drop-in anytime during the session. Bring your own computer. BTEP personnel will be available to answer questions about: Working at the Unix command line on Biowulf Quality control and Read More...
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Bioinformatics
07/31/2019 - Drop-in anytime during the session. Bring your own computer. We will be covering the following topics: - Unix bootcamp – learn to navigate a Unix file system and move, copy, and edit files - Looking Read More...
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Bioinformatics
06/12/2019 - Upcoming hands-on, drop-in BTEP sessions held in Frederick, Ft. Detrick, Bldg 549, Rm 549B Drop-in anytime during the session. Bring your own computer. BTEP personnel will be available to answer questions about: Working at the Read More...
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Bioinformatics
09/28/2018 - This event will be held in the Scientific Library, Bldg. 549, Ft. Detrick, Frederick. Please bring your own laptop. There will also be a limited number of classroom computers (PC) available. The Bioinformatics Training and Read More...
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Bioinformatics
04/26/2017 - The CCR Bioinformatics Training and Education Program (BTEP) is pleased to organize a workshop on Partek Genomics Suite for scientists at NCI-Frederick. Partek ® Genomics Suite ® is a versatile scientific software with an easy-to-use graphical Read More...
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Bioinformatics
03/29/2017 - The CCR Bioinformatics Training and Education Program (BTEP) is pleased to organize a workshop on Partek Flow for scientists at NCI-Frederick . Partek Flow software is designed specifically for the analysis needs of next generation Read More...
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Bioinformatics
06/13/2025 - Thi e ion will help participant of BTEP' Python introduction cour e with que tion related to cla .
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Bioinformatics
06/06/2025 - Thi e ion will help participant of BTEP' Python introduction cour e with que tion related to cla .
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Bioinformatics
03/25/2020 - THIS EVENT HAS BEEN CANCELLED Single-cell RNA sequencing (scRNA-Seq) is a rapidly evolving method in the field of single-cell genomics which has enhanced our ability to study biological processes at the cellular level. The Read More...
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Bioinformatics
02/26/2020 - Single-cell RNA sequencing (scRNA-Seq) is a rapidly evolving method in the field of single-cell genomics which has enhanced our ability to study biological processes at the cellular level. The CCR Collaborative Bioinformatics Resource (CCBR) Read More...
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Bioinformatics
02/12/2020 - RNA sequencing (RNA-Seq) is a widely used method in genomics, which enables the interrogation of whole cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a RNA-seq workflow on the Palantir collaboration platform, Read More...
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Bioinformatics
01/29/2020 - Single-cell RNA sequencing (scRNA-Seq) is a rapidly evolving method in the field of single-cell genomics which has enhanced our ability to study biological processes at the cellular level. The CCR Collaborative Bioinformatics Resource (CCBR) Read More...
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Bioinformatics
12/19/2019 - Drop-in anytime during the session. Bring your government-issued computer. Before coming to class, download a tool for transferring files. For Windows PC, suggested tool is WinScp . 2. For Mac, suggested tool is Filezilla . 3. For Windows Read More...
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Bioinformatics
12/18/2019 - THIS EVENT HAS BEEN CANCELLED Drop-in anytime during the session. Bring your own computer. Before coming to class, download a tool for transferring files. For Windows PC, suggested tool is WinScp . 2. For Mac, suggested Read More...
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Bioinformatics
11/20/2019 - Drop-in anytime during the session. Bring your own computer. Before coming to class, download a tool for transferring files. For Windows PC, suggested tool is WinScp . 2. For Mac, suggested tool is Filezilla . 3. For Windows Read More...
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Bioinformatics
10/30/2019 - Drop-in anytime during the session. Bring your own computer. Before coming to class, download a tool for transferring files. For Windows PC, suggested tool is WinScp . 2. For Mac, suggested tool is Filezilla . 3. For Windows Read More...
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Bioinformatics
09/25/2019 - Drop-in anytime during the session. Bring your own computer. Before coming to class, download a tool for transferring files. For Windows PC, suggested tool is WinScp . 2. For Mac, suggested tool is Filezilla . 3. For Windows Read More...
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Bioinformatics
06/05/2019 - You do not need to currently have an account on Biowulf to attend this class. Computers are provided in the classroom, you may also bring your own laptop. If you bring your own laptop, Read More...
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Bioinformatics
04/10/2019 - BTEP Wednesday, April 10, 2019 9:00 am | Eastern Daylight Time (New York, GMT-04:00) | 2 hrs Meeting number (access code): 738 427 711 Meeting password: zPJpWP$6 10x Genomics: Whole Exome and Whole Genome Analysis How 10x Genomics linked Read More...
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Bioinformatics
12/05/2018 - THIS EVENT HAS BEEN CANCELLED 10x Genomics: Whole Exome and Whole Genome Analysis How 10x Genomics linked reads works SNVs, copy number variations, structural variants and phasing of the variants from linked read data Read More...
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Bioinformatics
11/14/2018 - Experimental Design Considerations in Variant Analysis Germline vs Somatic WGS vs WES Sample sizes and statistical power WGS/WES Pipelines at NIH Pipeline performance Using Pipeliner for internal and external data Variant QC, Annotation Read More...
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Bioinformatics
12/14/2012 - All researchers at the NCI have unlimited access to Pathway Studio software, MedScan text mining module, and the Mammalian database. Pathway Studio Application Areas Include: • Disease Biology • Disease Biomarkers • Drug Target Identification • Protein Functionality • Read More...
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Bioinformatics
11/21/2024 - Dear FNL colleagues, It’s time once again for our last in 2024 Biotech Connector event!! The Frederick National Laboratory for Cancer Research together with the Frederick County Chamber of Commerce organizes the quarterly Biotech Read More...
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Bioinformatics
03/26/2024 - In this session, we will discuss the potential of GPUs, and when and why to use GPUs on the Frederick Research Computing Environment (FRCE). We will explore the possibilities of GPU-accelerated AI applications and Read More...
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Bioinformatics
01/23/2024 - In this session, we will discuss the potential of GPUs, and when and why to use GPUs on the Frederick Research Computing Environment (FRCE). We will explore the possibilities of GPU-accelerated AI applications and Read More...
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Bioinformatics
NCI Sequencing Facility (SF) - ATRF, Frederick NCI CCR Genomics Core (GC) - Bethesda, Bldg 37 NCI CCR Single Cell Analysis Facility (SCAF) - Bethesda, Bldg 37 NCI Genomics Technology Laboratory - ATRF, Frederick NIH Intramural Sequencing Read More...
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Bioinformatics
09/18/2024 - Frederick National Laboratory Science and Technology Group: Work in Progress Seminar Series presents: “Modernization of Next Generation Sequencing Big Data Analysis Pipelines Leveraging NIH’s on-prem High Performance Computing Cluster … and Cloud.” Meeting ID: 225 592 603 654 Read More...
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Bioinformatics
08/21/2024 - Frederick National Laboratory Science and Technology Group: Work in Progress Seminar Series presents: "Single Cell Characterization of Antigen-Specific Responses: An Immunomics Approach" Meeting ID: 225 592 603 654 Passcode: B7sey6
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Bioinformatics
01/17/2024 - Frederick National Laboratory Science and Technology Group: Work in Progress Seminar Series presents: “Enhancing Data Exploration, User Experience and Curation Efficiency in caNanoLab with Large Language Model”
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Bioinformatics
10/24/2023 - In this session, we will provide an overview of the Next-Generation Sequencing (NGS) capabilities and applications. We will present the workflows and analyses for Illumina short-read, PacBio, and Oxford Nanopore long-read sequencing on Frederick Read More...
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Bioinformatics
08/15/2023 - This talk will cover what to do when you first start looking at a new dataset. We will also discuss how to efficiently orient the data to avoid pitfalls and maximize knowledge gain in Read More...
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Bioinformatics
03/08/2022 - Are you interested in growing your data science skills or connecting with like-minded practitioners at NCI? Join us on March 8, 3:00 pm – 4:00 pm ET for a seminar on data science resources available to NCI staff! Read More...
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Bioinformatics
06/24/2025 - Thi year the Frederick Re earch Compute Environment (FRCE) i expanding it outreach. Our fir t new feature i a web-ba ed tool that will allow you to ea ily run graphical application on Read More...
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Bioinformatics
03/12/2025 - Clustering is one of the fundamental unsupervised machine learning algorithms. It is often used to group quantitative proteomic or RNAseq expression data to suggest sub-types of a particular cancer. This presentation covers building a Read More...
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Bioinformatics
01/28/2025 - This talk will cover how our group uses the resources of the FRCE cluster to process cryo-electron microscopy data collected in-house. This session is geared towards beginner users. This session will be recorded, and Read More...
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Bioinformatics
01/15/2025 - This session of the BTEP Coding Club will demonstrate how to use the R package “survival” to conduct a survival analysis of an example dataset. Senior Programmer and Analyst, Duncan Donohue, PhD, will cover Read More...
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Bioinformatics
01/14/2025 - In this talk, we will cover the basics of survival analysis as a statistical methodology developed for censored data. Special emphasis will be on visualizing survival data, comparing survival-time distributions for subject groups, and Read More...
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Bioinformatics
11/26/2024 - This talk will introduce quantum chemistry and how it is useful for the modeling of therapeutic and diagnostic agents. This session is geared towards beginners. This session will be recorded, and materials will be Read More...
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Bioinformatics
11/12/2024 - We will discuss statistical considerations in planning, executing, and interpreting experiments using animals. Topics will include interpreting minimally powered pilot studies, dealing with complex time series, and maximizing knowledge gain from limited resources. This Read More...
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Bioinformatics
10/22/2024 - Popular structure prediction program AlphaFold3 and its competitor Chai-1 recently added capabilities to predict 3D RNA structures straight from sequence input. In this talk, we will discuss some test cases for these programs and Read More...
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Bioinformatics
10/08/2024 - We will cover recently developed statistical approaches to the classification of BRCA2 variants using the functional-assay data generated by our NCI collaborators (Dr. Sharan’s lab). Our main objective is to illustrate how statistical Read More...
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Bioinformatics
08/13/2024 - This session will cover the basics of linear mixed-effects modeling as a method of regression analysis for clustered data. Special emphasis will be on the ideas behind random-intercepts and random-slopes modeling, and the discussion Read More...
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Bioinformatics
07/23/2024 - In this presentation, we will demonstrate how to use enterprise data science platform to configure, run, share, and scale downstream bioinformatics and image analysis pipelines using cloud and HPC resources. This session is geared Read More...
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Bioinformatics
06/11/2024 - This talk will cover the basics of statistical resampling methods such as bootstrap, Monte Carlo, and permutations for estimating parameters and testing hypotheses. We will discuss when you might want to use Read More...
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Bioinformatics
05/14/2024 - This presentation will explain the difference between the mean and standard deviation of a set of values and the standard error of the mean. The parameters involved in comparing two normally distributed populations relative Read More...
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Bioinformatics
04/23/2024 - Crunching of large data requires large resources. Exploration of holobiont metagenomes is considered a “big data” project and here I’ll be describing how I used the FRCE Read More...
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Bioinformatics
04/16/2024 - GitHub is a powerful platform for tracking, sharing, and collaborating on software projects of all kinds. Whether you’re a bioinformatics analyst, a software engineer, or a biologist who sometimes codes, GitHub Read More...
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Bioinformatics
04/09/2024 - In this talk, we will cover what differentiates parametric and non-parametric statistics, tests/methods of both types for different data scenarios, when to use one vs. the other, and tradeoffs/pitfalls of each. This Read More...
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Bioinformatics
11/28/2023 - Recent advances in protein structure prediction methods such as AlphaFold2 and ESMFold has enabled protein structure prediction to achieve experimental accuracy in certain cases. In this talk, we will discuss the advantages and limitations Read More...
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Bioinformatics
09/12/2023 - In this talk we will discuss how and why to minimize and correct for batch effects in our experiments. We will cover appropriate sample randomization and several computational methods to help uncover and mitigate Read More...
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Bioinformatics
This tool was created and is maintained by the Laboratory of Human Retrovirology and Immunoinformatics at Frederick National Lab. DAVID is used for functional analysis. Given an input gene list, DAVID will inform us of Read More...
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Bioinformatics
This tool was created and is maintained by the Laboratory of Human Retrovirology and Immunoinformatics at Frederick National Lab. DAVID is used for functional analysis. Given an input gene list, DAVID will inform us of Read More...
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Bioinformatics
Biostar Class - Sequencing Instruments Below are a list of links and resources mentioned in the BIOSTAR Sequencing Instruments class given on 06/10/20 and 06/11/20 Sequencing Technologies - Company Web Sites Illumina PacBio Oxford Nanopore 10X Genomics Read More...
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Bioinformatics
09/12/2022 - We welcome members of the NIH to join us for a seminar event, covering multiplexed, direct digital gene expression profiling applications utilizing NanoString nCounter expression profiling technology as well as spatial biology discoveries generated Read More...
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Bioinformatics
08/23/2022 - This event has been cancelled and will be rescheduled. Are you clear on how deep learning fits into Machine Learning? Confused about the difference between training, testing, and validation datasets? Join us for an Read More...
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Bioinformatics
03/08/2022 - Please join us for an LCB webinar next Tuesday, March 8, 2:00-3:00, via ZoomGov Dr. Thomas Gonatopoulos-Pournatzis, Stadtman Investigator, RNA Biology Laboratory, Functional Transcriptomics Section, NCI Frederick (guest of Pedro Batista) will present a lecture: Read More...
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Bioinformatics
10/28/2021 - Please join us for a discussion followed by question and answer session on the topic of “R or Python, Which Should I Learn?”. We will be joined by Andrew Weisman of the Frederick National Read More...
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Bioinformatics
09/23/2021 - Meeting Link: https://cbiit.webex.com/cbiit/j.php?MTID=m5fa0e43ae167ed5ea3a77fb25d339a82 TOPIC: AI for Multimodal Data, presented by members of the Strategic Data Science Initiative, Read More...
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Bioinformatics
09/23/2021 - Registration: https://btep.ccr.cancer.gov/classes/ai_four/ Meeting Link: https://cbiit.webex.com/cbiit/j.php?MTID=m5fa0e43ae167ed5ea3a77fb25d339a82 Description: In this talk, we Read More...
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Bioinformatics
09/14/2021 - The workshop focuses on using the Atom Modeling PipeLine (AMPL), an open-source conda-based software that automates key drug discovery steps. AMPL is designed to take molecular binding data (IC50, ki) and carry out the Read More...
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Bioinformatics
05/26/2021 - Webex Are you clear on how deep learning fits into machine learning? Confused about the difference between training, testing, and validation datasets? Join us for an overview of common machine learning terminology. While this Read More...
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Bioinformatics
01/19/2021 - Overview Are you interested in improving your machine or deep learning models? You often cannot be sure you've developed the best model without performing hyperparameter optimization. In this talk, we will explain what Read More...
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Bioinformatics
10/20/2020 - Register R markdown offers tools to generate and update reports automatically—including figures, tables, mathematical equations and code. Instead of copying tables and figures into another document, you can update reports quickly and easily Read More...
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Bioinformatics
09/22/2020 - [one_half] This two-part workshop will demonstrate how deep learning can be used to classify different types of cancer. Part I will focus on data preparation, starting with genomic data. Part II will demonstrate Read More...
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Bioinformatics
There are two main Core facilities providing DNA sequencing services for CCR scientists. CCR Sequencing Facility Located at the ATRF in Frederick provides production quality high throughput sequencing service to the CCR community. Their service Read More...
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Bioinformatics
05/16/2016 - This 2-day course, which includes both lecture and hands-on components, will teach the basic concepts and practical aspects of ChIP-Seq Data Analysis. There will also be a talk on ENCODE and a comprehensive discussion Read More...
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Confocal
Confocal Microscope Image of Fixed Mouse Embryonic Fibroblast (MEF) Cells Actin proteins (stained red) and Tubulin proteins (stained green) are involved in a number of cellular process such as cell motility, cell division and maintenance Read More...
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Bioinformatics
07/09/2025 - This session of the BTEP Coding Club will demonstrate the use of R programming to perform decision tree analysis, survival tree analysis, and random forest. This event complements a Statistics for Lunch event, " Read More...
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Bioinformatics
BTEP strives to maintain links to resources that should be of interest to CCR Bioinformatics Community. Some of the resources to will be accessible through more than one of these lists, but since the lists Read More...
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Bioinformatics
07/11/2024 - Please join us for this special event featuring three speakers on the topic of Single-Cell Spatial Transcriptomics. George Zaki, Ph.D., Director, Applied Scientific Computing, BACS, The Frederick National Lab for Cancer Research, NCI/ Read More...
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Bioinformatics
The Advanced Biomedical Computational Science (ABCS) group focuses on applications of bioinformatics, computational and data science, and artificial intelligence to support NCI researchers. ABCS provides: • Subject matter expertise in genomics, proteomics, and imaging. • Machine learning/ Read More...
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Bioinformatics
High resolution single cell profiling assays have provided an unprecedented view of many biological systems and processes, but the spatial context in which this biology is occurring is often crucial. Spatial profiling, including spatial transcriptomic Read More...
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Bioinformatics
06/14/2022 - Python is one of the preferred programming languages for scientists to solve a wide variety of biological problems. We find that many scientists who come to Software Carpentry workshops use Python and want to Read More...
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Bioinformatics
06/07/2022 - Python is one of the preferred programming languages for scientists to solve a wide variety of biological problems. We find that many scientists who come to Software Carpentry workshops use Python and want to Read More...
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Bioinformatics
05/31/2022 - Python is one of the preferred programming languages for scientists to solve a wide variety of biological problems. We find that many scientists who come to Software Carpentry workshops use Python and want to Read More...
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Bioinformatics
05/24/2022 - Python is one of the preferred programming languages for scientists to solve a wide variety of biological problems. We find that many scientists who come to Software Carpentry workshops use Python and want to Read More...
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Bioinformatics
05/17/2022 - Python is one of the preferred programming languages for scientists to solve a wide variety of biological problems. We find that many scientists who come to Software Carpentry workshops use Python and want to Read More...
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Bioinformatics
05/10/2022 - Overview Python is one of the preferred programming languages for scientists to solve a wide variety of biological problems. We find that many scientists who come to Software Carpentry workshops use Python and want Read More...
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Bioinformatics
05/04/2022 - Presenter: Thomas Gonatopoulos-Pournatzis, Ph.D. Stadtman Investigator NIH Distinguished Scholar Head Functional Transcriptomics Section RNA Biology Laboratory NCI-Frederick Dr. Gonatopoulos-Pournatzis studies the regulatory pathways and functional roles of alternative splicing and other pre-mRNA processing Read More...
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Bioinformatics
10/28/2021 - For NCI Coursera license holders. Please join us for a discussion followed by question and answer session on the topic of "R or Python, Which Should I Learn?". Meeting Link: https://cbiit. Read More...
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Bioinformatics
06/09/2021 - The CCR Office of Science and Technology Resources (OSTR) is pleased to host a virtual technology seminar given by Advanced Cell Diagnostics (ACD) and NCI Cores at FNLCR. Presenters: Jyoti Phatak, MS | Advanced Cell Read More...
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Bioinformatics
06/08/2021 - Do you want to know how to use Machine Learning (ML) for accelerating drug discovery? Join us on June 8, 1:00 pm – 2:00 pm ET, for the first in a series of workshops on how to use Read More...
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Bioinformatics
05/25/2021 - Registration is required. Register at this link . Python is a good programming language for scientists to solve a wide variety of biological problems. We find that many scientists who come to Software Carpentry workshops Read More...
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Bioinformatics
05/18/2021 - Registration is required. Register at this link . Python is a good programming language for scientists to solve a wide variety of biological problems. We find that many scientists who come to Software Carpentry workshops Read More...
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Bioinformatics
05/11/2021 - Registration is required. Register at this link . Python is a good programming language for scientists to solve a wide variety of biological problems. We find that many scientists who come to Software Carpentry workshops Read More...
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Bioinformatics
05/04/2021 - Registration is required. Register at this link . Python is a good programming language for scientists to solve a wide variety of biological problems. We find that many scientists who come to Software Carpentry workshops Read More...
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Bioinformatics
04/27/2021 - Registration is required. Register at this link . Python is a good programming language for scientists to solve a wide variety of biological problems. We find that many scientists who come to Software Carpentry workshops Read More...
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Bioinformatics
04/20/2021 - Registration is required. Register at this link . Before the workshop: We will use Google Colab for this workshop. Colab allows us to write and execute Python code through the browser. A Google Account is Read More...
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Bioinformatics
03/05/2021 - Speaker: Patrick D. Schloss, PhD Frederick G. Novy Collegiate Professor of Microbiome Research Department of Microbiology & Immunology University of Michigan Medical School Abstract: The “reproducibility crisis” in science affects microbiology as much Read More...
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Bioinformatics
12/01/2020 - Please Register to join us for a virtual workshop focused on defining the major challenges and promising new approaches for creating, curating, integrating, and querying across ultra-large chemistry databases. This event is a Three Read More...
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Bioinformatics
05/20/2020 - Advances in technology have reduced the cost of single cell sequencing, opening the doors to many new areas of study including transcriptome, DNA genomics, epigenomics and microbial systems. This workshop, provided by experts from Read More...
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Bioinformatics
04/25/2018 - Join us for a seminar/webinar session where Partek Specialist will show you how to analyze your Single Cell RNA-Seq data in an intuitive, interactive and powerful way using Partek Flow. The solution simplifies Read More...
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Bioinformatics
04/25/2017 - This talk will be an introduction to Methyl-seq, where you will learn about leveraging the power of next-generation sequencing (NGS), both genome-wide and targeted approaches, that can provide insight into methylation patterns at a Read More...
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Bioinformatics
03/29/2017 - The CCR Bioinformatics Training and Education Program (BTEP) is excited to arrange its inaugural informational presentation for the CCR scientific community at NCI-Frederick. Date: Wednesday, March 29, 2017 Time: 11:00 am - 12:00 pm Location: ATRF Room E-1106 Read More...
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Bioinformatics
06/06/2016 - The 'NCBI Resources for CCR Scientists' workshop, on June 6 and June 8, 2016, will focus on teaching a wide range of resources developed within NCBI that are relevant for CCR scientists. It will include both hands-on Read More...
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Confocal
Gianluca Pegoraro, PhD gianluca.pegoraro@nih.gov Facility Head 240-760-6696 Bldg. 41, Room B909 Dr. Pegoraro received his Ph.D. in Molecular Genetics from the International School of Superior Studies in Trieste, Italy in 2004. After Read More...
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Confocal
Gianluca Pegoraro, PhD gianluca.pegoraro@nih.gov Facility Head 240-760-6696 Bldg. 41, Room B909 Dr. Pegoraro received his Ph.D. in Molecular Genetics from the International School of Superior Studies in Trieste, Italy in 2004. After Read More...
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Confocal
Training We recommend that users become familiar with the principals of fluorescence labeling and optical microscopy before arranging for training. We recommend the following sites for learning about microscopy: Introductions to Fluorescence Microscopy Fluorescence Labeling Read More...
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Bioinformatics
Long read sequencing was recently named 2022’s method of the year by Nature Methods . Long read sequencing technologies, those that generate sequence reads with lengths of 10s of kilobases or longer have several advantages over Read More...
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Bioinformatics
Database for Annotation, Visualization and Integrated Discovery (DAVID) - an overview Before getting started, remember to be signed on to the DNAnexus GOLD environment. Lesson 17 review In the previous class, we got an overview of Read More...
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Bioinformatics
Database for Annotation, Visualization and Integrated Discovery (DAVID) - an overview Lesson 17 review In the previous class, we got an overview of functional and pathway analysis, which help to put RNA sequencing results into biological Read More...
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CRTP
How do I determine which EM technique should be used for my research? Schedule a free consultation with the Head of EMC, Dr. Ru-ching Hsia, to discuss the aim of your research project. Dr.& Read More...