Search Results for: Second-harmonic generation imaging microscopy (SHIM)

The Center for Advanced Tissue Imaging (CAT-I) is an NIAID and NCI supported effort involving collaborative studies between experts in the Laboratory of Immune System Biology, DIR, NIAID and investigators in the DIR, NIAID and Read More...

CCR VOLUME Electron Microscopy Core (CVEMC),  formerly known as volume Electron Microscopy (vEM), aims to develop new techniques in volume electron microscopy (vEM) and, in collaboration with CCR Investigators, apply these techniques to research cell Read More...

The Electron Microscopy Core (EMC), formerly known as Electron Microscopy Lab (EML),  offers investigators access to unique expertise and EM technologies that allow CCR Investigators to explore new avenues of research in order to enhance Read More...

As a multi-user facility, the different instruments provide a wide range of imaging modes for EIB scientists, from standard immunohistochemistry, through brightfield and wide-field epifluorescence imaging, to highly complex live cell confocal microscopy and super-resolution Read More...

LCMB Microscopy Core offers live cell imaging technologies as well as super-resolution, fluorescence lifetime and confocal imaging systems for immunofluorescence. Our confocal instruments are a Leica SP8 laser scanning confocal microscope and a Nikon spinning Read More...

The core provides access to several different state-of-the-art 3D microscopes as well as computers to visualize and process image data. The facility houses equipment for 2D or 3D imaging of fixed and living specimens. High Read More...

The LCBG Microscopy Core offers imaging technologies and training. The Core has established instrumentation for for 2D and 3D imaging of both fixed and living specimens.

Volume electron microscopy: A powerful, nanoscale-resolution, 3D imaging approach now available to the cell biologist Kedar Narayan, Ph.D., Senior Scientist & Group Leader, CCR Volume Electron Microscopy, Cancer Research Technology Program (CRTP), Frederick National Laboratory, Read More...

The NHLBI Murine Phenotyping Core carries out physiologic and behavioral testing in a diversity of mouse models for NHLBI and other NIH institutes.Established TechnologiesCardiovascular Phenotyping, Metabolic Phenotyping, Pulmonary Phenotyping, Behavioral Phenotyping, Exercise Physiology, Echocardiography, Read More...

The Biomedical Engineering and Physical Science (BEPS) shared resource supports NIH’s intramural basic and clinical scientists on applications of engineering, physics, imaging, measurement, and analysis. BEPS is centrally located on the main NIH campus Read More...

The NIH MRI Research Facility (NMRF) is a shared, intramural resource for human imaging studies. The NMRF is supported by all Institutes at NIH and reports to the Shared Resources Subcommittee (SRS) of the Scientific Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx User Survey The CREx Team is carrying out a CREx User Survey. If you haven’t Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx User Survey The CREx Team is carrying out a CREx User Survey. We would greatly appreciate Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New NIH Resource Resources Advance your research with the NIH Mouse Imaging Facility (MIF) The NIH Mouse Imaging Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New Resources on CREx Interested in imaging large scale biological samples?  Volume electron microscopy allows for Read More...

NanoString Technology The nCounter® Analysis System is an automated, multi-application, digital detection and counting system which directly profiles up to 800 molecules simultaneously from a single sample using a novel barcoding technology. Profile hundreds of mRNAs, Read More...

CREx News & Updates July 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Click below to learn how easy it is to navigate the CREx platform. These short videos will Read More...

Many established and emerging technologies are available to CCR scientists.  This technology-rich environment makes the CCR a unique place to conduct scientific research.  Through the OSTR, the CCR continues to find Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Research Festival The NIH Research Festival highlights the groundbreaking science and the vibrant NIH community driving our Read More...

Employing spatial biology techniques enables acquisition of transcript and protein data from intact tissue sections, and in turn, spatial distribution information and cellular interaction patterns are revealed.

October 6, 2022 crex.nih.gov CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight NIH Center For Human Immunology, Inflammation, And Autoimmunity (CHI) CHI is a Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx Program Manager The CREx Team is happy to announce Deepika Velampati as the new CREx Program Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New NIH Resource Resources Derive Greater Insights and Accelerate your Research Using Bioinformatic Tools! CREx is an NIH Read More...

The Pathology Service, Division of Veterinary Resources (DVR), Office of Research Services (ORS), provides diagnostic gross and histopathologic evaluation of any species of laboratory animals used in the NIH Intramural Research Program due to morbidity, Read More...

The CCR Genomics Core is located in Building 41 on the NIH Bethesda campus. The primary goal of the Core is to provide investigators from CCR/NCI and other NIH Institutes access to genomic technologies and Read More...

The Chemistry and Synthesis Center (CSC) of the National Heart, Lung, and Blood Institute (NHLBI) provides IRP scientists with targeted imaging probes and chemical tools that help accelerate cell-based assays, in vivo imaging studies, and Read More...

The NCI Cloud Resources are components of the NCI Cancer Research Data Commons (CRDC) that bring data and computational power together to enable cancer research and discovery. These cloud-based platforms eliminate the need for researchers Read More...

The FNLCR Molecular Histopathology Laboratory (MHL) provides comprehensive veterinary pathology support for animal health monitoring, biomarker discovery and validation, drug development, genomics, and proteomics on a cost recovered basis. The MHL is organized into multiple Read More...

CLIA-Certified Technologies Offered: Fragment Analysis for Micro-satellite Instability Detection, Pharmacoscan Array for Pharmacogenomics, Mutation Detection for PCR and Sanger Sequencing, DNA extraction from whole blood, saliva, FFPE tissues, buccal swabs, nails, hair, PBMCs, buffy coats, Read More...

The Frederick Sequencing and Genomics Core (FSGC) was established through the integration and consolidation of the former Sequencing Facility (SF) and the Genomics Technology Laboratory (GTL). The new FSGC eliminates redundancy and provides cutting edge Read More...

The Neurorehabilitation and Biomechanics Research Section (also referred to as the NAB LAB) is a multidisciplinary group of highly qualified scientists, clinical and technical staff, and trainees with diverse backgrounds including medical, physical therapy, neuroscience Read More...

The Molecular Pathology Unit is intended to spearhead opportunities for bridging basic and clinical research efforts by more precisely optimizing the development, characterization, and utilization of models of human disease. The initiative approach includes both Read More...

The CCR Collaborative Bioinformatics Resource (CCBR) is a centrally funded resource group which provides a mechanism for CCR researchers to obtain many different types of bioinformatics assistance to further their research goals. The group has Read More...

The NCI Genomic Data Commons (GDC) was established by the NCI Center for Cancer Genomics (CCG) to support the receipt, harmonization, distribution, and analysis of genomic and clinical data from cancer research programs. The GDC Read More...

The Mass Cytometry Core (MCC) provides access to cutting-edge platforms and expert technical support for high-dimensional single-cell analysis and spatial proteomic profiling. A central expertise of the core is Imaging Mass Cytometry (IMC), which allows Read More...

NIH Intramural CryoEM Consortium (NICE) serves intramural investigators in all NIH IC’s. NICE provides access to state-of-the-art Titan Krios cryo-electron microscopes for atomic-resolution structure determination of protein, macromolecular complexes, membrane receptors, cellular organelles, and Read More...

The Clinical Image Processing Service (CIPS) offers timely and accurate advanced image processing of diagnostic radiology images for clinical care, research, and training. CIPS’ functions include clinical services and scientific researches. Established Technologies CIPS can Read More...

The Division of Veterinary Resources Animal Surgery has supported large animal research and clinical care for more than 40 years. DVR surgeons provide outstanding and highly specialized large animal (rabbits, ungulates, etc.) research support in a Read More...

The PET Department, CC, functions as a core facility that supports basic, translational, and clinical research using PET. It is a vertically integrated facility, with resources to produce positron-emitting radionuclides, manufacture PET radiopharmaceuticals in a Read More...

The NIH Biowulf Cluster provides researchers with a world-class system to assist in solving complex biomedical problems as diverse as gene variation in worldwide human populations, deep learning to model protein structures, and PET brain Read More...

NISC’s role within NHGRI, and more broadly across NIH, aims to advance genome sequencing and its many applications, with a goal not simply to produce sequence data, but to produce the infrastructure required to Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Intramural Core Resources NHGRI Flow Cytometry Core The Core performs high quality single cell analysis through the Read More...

October 6, 2022 crex.nih.gov CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Science & Technology Seminars and Training Events Upcoming Seminars and Educational Opportunities The following Read More...

September 8, 2022 crex.nih.gov CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight Trans-NIH Intramural Sequencing Center (NISC) NISC is a multi-disciplinary genomics facility that Read More...

The research conducted within the Synthetic Biologics Core (SBC) Facility has a dual role: Generate chemical biology tools and drug candidates for molecular targets identified by NCI research groups, Develop novel effective methods and tools Read More...

The National Cancer Institute (NCI) is developing a national repository of Patient-Derived Models (PDMs) comprised of patient-derived xenografts (PDXs), patient-derived organoids (PDOrg), and in vitro patient-derived tumor cell cultures (PDCs) and cancer-associated fibroblasts (CAFs). These Read More...

OSTR provides CCR investigators with access to a variety of software licenses for genomic, proteomic, pathway analysis and data visualization tools. These software are funded by OSTR and made available at no cost to CCR Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New Resources on CREx NCI CLIA Molecular Diagnostics Laboratory (CMDL) The NCI CMDL is available to assist all Read More...

Our operational objectives are to provide state-of-the-art OMICS technologies in support of the Genetics Branch (GB) investigators and collaborators. Research Services Wet Lab Single cell isolation from fresh, frozen, and FFPE tissue, DNA/RNA extractions Read More...

CREx News & Updates December 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight FACILITY HIGLIGHTS Learn more about services from the STRIDES Initiative. VIEW STRIDES INITIATIVE NIH Cores Read More...

NCI LASP Genome Modification Core (GMC) is a CCR-dedicated facility that provides advice, training, and reagents to NCI scientists seeking to utilize CRISPR and other nucleases to generate genome modifications in primary cells, cell lines, Read More...

Employing spatial biology techniques enables acquisition of transcript and protein data from intact tissue sections, and in turn, spatial distribution information and cellular interaction patterns are revealed.

CREx News & Updates August 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGHLIGHTS Learn more about services from the NHLBI Read More...

CREx News & Updates January 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight NCI ANTIBODY CHARACTERIZATION LABORATORY (ACL) The ACL specializes in rigorously validating antibodies for signaling and Read More...

The NIH Center for Human Immunology, Inflammation, and Autoimmunity (CHI) is a trans-NIH resource whose mission is to provide a collaborative hub of advanced translational immunology for NIH clinical and pre-clinical studies. This uniquely structured Read More...

We are a bioinformatics team within the Center for Biomedical Informatics and Information Technology’s (CBIIT’s) Cancer Informatics Branch (CIB)—soon to be referred to as the Informatics and Data Science (IDS) Program. Headed Read More...

September 8, 2022 crex.nih.gov CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Science & Technology Seminars and Training Events Upcoming Seminars and Educational Opportunities The following Read More...

CREx News & Updates March 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight NIA Nonhuman Primate Core The NIA Nonhuman Primate Core supports multi-disciplinary translational aging projects for Read More...

Mouse models of human cancer have had a profound impact on our current understanding of the mechanisms of tumorigenesis and the pathways regulated by cancer-related genes. These models hold the promise of serving as critical Read More...

CREx News & Updates November 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight FACILITY HIGLIGHTS Learn more about services from the NINDS Quantitative Magnetic Resonance Imaging Core. NINDS Read More...

The Staff Scientists/Clinicians (SSSC) Technical Enrichment Program (STEP) was established to provide SSSC’s an opportunity to compete for funding to gain comprehensive training in state-of-the-art techniques available through CCR Cores and Facilities. The Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New NIH Resource Spotlight The NIH Lab Managers Working Group have developed a new NIH-wide database of cold Read More...

Molecular Cytogenetics Core Facility facilitates the assessment of structural and numerical genomic changes in pre-cancer and cancer research models. This core provides comprehensive support for the cytogenetic analysis of cells from human and research animal Read More...

The Department of Laboratory Medicine provides state-of-the-art laboratory testing in support of Clinical Center patient care and will serve as a center of excellence in research and training in laboratory medicine, particularly in areas which Read More...

The OSTR offers cutting-edge technology platforms to the CCR scientific community through centralized facilities. The videos accessed through this page are designed to introduce the various scientific methodologies OSTR makes available through the cores on Read More...

The CCR Animal Resource Program (ARP) plans, develops, and coordinates laboratory animal resources for CCR’s research programs. We also provide training, imaging, and technology development in support of moving basic discoveries to the clinic. Read More...

[tabby title="Home"] About NICE-NIH Intramural CryoEM Consortium  NIH Intramural CryoEM Consortium (NICE) serves intramural investigators in all NIH IC’s. NICE provides access to state-of-the-art Titan Krios cryo-electron microscopes for atomic-resolution structure determination of Read More...

The Antibody Engineering Program (AEP) is part of the Center for Cancer Research (CCR) at the National Cancer Institute (NCI). The program focuses on generating therapeutic antibodies by phage display technology, including human antibodies and Read More...

In support of Intramural Research Program (IRP) scientists, DOHS provides training, consulting, and resources to ensure that workers' risk to hazards and stresses in the laboratory environment is minimized. Our services include one-on-one consultation with Read More...

CREx News & Updates October 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGLIGHTS Learn more about services from the CPTR Read More...

CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Cores on CREx NIBIB BEPS Micro Analytical Immunochemistry Unit The Micro Analytical Immunochemistry Unit employs a variety Read More...

CREx News & Updates June 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGHLIGHTS Visit here to learn about services from Read More...

October 6, 2022 crex.nih.gov CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Science & Technology Seminars and Training Events Upcoming Seminars and Educational Opportunities The following Read More...

Proteomic Data Common (PDC) represents the NCI’s largest public repository of proteogenomic comprehensive tumor datasets, essentially a Proteogenomic Cancer Atlas. It was developed to advance our understanding of how proteins help shape the risk, Read More...

What is Xenium? Xenium is a high-resolution, imaging-based in situ spatial profiling technology from 10x Genomics that allows for simultaneous expression analysis of RNA targets (currently in range of 100’s) within the same tissue section. Read More...

The Laboratory Animal Sciences Program (LASP) of the Frederick National Laboratory operates a Gnotobiotics Facility (GF) to support research focused on the role of microbiota in cancer inflammation, pathogenesis, and treatment response. The GF can Read More...

CREx News & Updates June 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Click below to learn how easy it is to navigate the CREx platform. These short videos will Read More...

CCR Office of Science and Technology Resources (OSTR) The Center for Cancer Research (CCR) Office of Science and Technology Resources (OSTR) explores and evaluates the latest technologic advancements and then makes them available to all Read More...

The Flow Cytometry Core (LGI) offers established technologies to support studies using flow cytometry and cell sorting. Established Technologies Applications that run on FACS Caliburs include: Immunophenotyping (up to 4-color), Intracellular markers, including cytokines and Read More...

Supplemental Technology Award Review System (STARS) Overview STARS Request Form STARS System The Supplemental Technology Award Review System (STARS) is a web-based interface for submission and review of S&S supplement requests by CCR Read More...

04/10/2025 - This one hour online training introduces participants to the tools and techniques for analyzing and quantifying microscopy images using MATLAB’s low-code algorithms. Participants will learn how to preprocess images, segment regions Read More...

03/04/2024 - The NCI Cancer Imaging Program presents a new monthly webinar series highlighting advancements in our imaging community. Please join us for our next lecture in the series Dr. McNally earned her Ph.D. in Read More...

02/21/2024 - The remarkable advances of artificial intelligence (AI) technology are revolutionizing established approaches to the acquisition, interpretation, and analysis of biomedical imaging data. Development, validation, and continuous refinement of AI tools requires easy access to Read More...

04/28/2022 - This webinar will provide a foundation on NCI’s  Imaging Data Commons  (IDC) and NCI Cloud Resources, components of the cloud-based  Cancer Research Data Commons  (CRDC). All  American Association of Physicists in Medicine  (AAPM)  Read More...

11/19/2021 - High-resolution, whole-brain microscopy provides unprecedented new insights into the brain’s structural organization, molecular diversity and connectivity. The Brain Image Library (BIL) provides infrastructure that facilitates the sharing of this valuable data, enabling investigators Read More...

05/20/2024 - Hybrid (in-person location in Rockville, MD) Virtual attending via  WebEx Meeting, link will be available two weeks prior to the meeting date . Attend the  2024 Co-Clinical Imaging Research Resource Program (CIRP) Read More...

02/21/2023 - Please plan to attend the Earl Stadtman Investigator Program search seminar by: Stephanie Harmon, Ph.D. Molecular Imaging Branch (MIB), CCR hosted by the MIB  Dr. Harmon is a Staff Scientist in the MIB Read More...

2024 Date: Tuesday, October 15, 2024 Time and Location: 11 am EST, ZOOM (INVITATION BY LMIG LIST SERVER) Speaker: Dr. Diego Presman (U Buenos Aires) Title: “Insights on Glucocorticoid Receptor Activity Through Live Cell Imaging” Summary: Eucaryotic transcription factors ( Read More...

05/29/2025 - Prostate cancer exhibits significant intratumoral heterogeneity, driving a spectrum of phenotypes ranging from indolent disease to aggressive metastasis, challenging risk stratification and treatment. A key feature of this heterogeneity is clonal diversity, encompassing both Read More...

03/26/2025 - Developing artificial intelligence (AI) schemes to assist the clinician towards enabling precision medicine approaches requires development of objective markers that are predictive of disease response to treatment or prognostic of longer-term patient survival. The Read More...

03/19/2025 - Clinical Molecular Imaging AI

04/23/2024 - Dr. Stephanie Harmon obtained her Ph.D. in medical physics at the University of Wisconsin–Madison and did her postgraduate training at Leidos Biomedical Research where she worked within the Molecular Imaging Read More...

04/22/2024 - Dear Colleagues,    In this webinar, you'll get an introduction to XNAT. XNAT is an open-source platform for managing, processing, and sharing medical imaging and related data in research settings. & Read More...

09/21/2023 - Picture this… You have large amounts of siloed medical imaging data, but you don’t have the time or budget to manually prepare the images and datasets for annotation and analysis. Don’t you Read More...

08/15/2023 - Picture this… You have large amounts of siloed medical imaging data, but you don’t have the time or budget to manually prepare the images and datasets for annotation and analysis. Don’t you Read More...

07/20/2023 - Picture this… You have large amounts of siloed medical imaging data, but you don’t have the time or budget to manually prepare the images and datasets for annotation and analysis. Don’t you Read More...

06/21/2023 - Picture this… You have large amounts of siloed medical imaging data, but you don’t have the time or budget to manually prepare the images and datasets for annotation and analysis. Don’t you Read More...

01/15/2026 - Gil Kanfer, PhD, of the NCI CCR High-Throughput Imaging Facility (HiTIF), in the Laboratory of Receptor Biology and Gene Expression (LRBGE) , will present the spatial biology analysis stack HiTIF is building to support Center Read More...

11/05/2025 - This talk delves into the innovative utilization of generative AI in propelling biomedical research forward. By harnessing single-cell sequencing data, we developed scGPT, a foundational model that extracts biological insights from an extensive dataset Read More...

09/17/2025 - Examples of combining visualization and computation in brain imaging. 

11/10/2022 - Join Google’s Marcos Novaes, Ph.D., as he presents on the design of large-scale solutions for high-performance computing, machine learning, and the internet of things using the Google Cloud Platform. Dr. Norvaes will Read More...

05/02/2022 - Federated Learning (FL) has emerged as a potential solution due to its capability in training models without sharing data. To enable effective FL in real applications, a robust communication framework is crucial. Join Drs. Read More...

05/03/2021 - Register/Join In the May NCI Imaging and Informatics Community Webinar, Dr. Chad Quarles will highlight how the improved understanding of the biophysics of contrast mechanism underlying dynamic susceptibility contrast (DSC) MRI is informing Read More...

04/22/2021 - Presenter: Dr. Bernadette Redd is Lead Radiologist, Body MRI, Radiology and Imaging Sciences, at the NIH Clinical Center. Dr. Redd earned her Doctorate in Medicine from the Columbia University College of Physicians and Surgeons Read More...

11/06/2012 - Introduction of Next-Generation Sequencing   This seminar will provide an overview of Next Generation DNA Sequencing. Highlighting Illumina sequencing technology, and its application in the areas of DNAse-seq, ChIP-seq, and RNA-seq, as well as Genomic Read More...

03/01/2024 - Jens Rittscher is Professor of Engineering Science at the University of Oxford with his appointment held jointly between the Institute of Biomedical Engineering and the Nuffield Department of Medicine. He is a group leader Read More...

02/15/2024 - This lesson will be divided into two parts. Part 1 will introduce Bioconductor, an R package repository for the analysis of biological data. Part 2 will introduce RMarkdown and Quarto for report generation with R.

This lesson will be divided into two parts. Part 1 will introduce Bioconductor, an R package repository for the analysis of biological data. Part 2 will introduce RMarkdown and Quarto for report generation with R.

05/23/2023 - In this webinar, University of Wisconsin-Madison’s Dr. Tiwari shares how she and her laboratory have created machine learning (ML) techniques to better understand the basic biology of tumors through non-invasive imaging, Read More...

05/02/2023 - Participants will learn how to develop artificial intelligence (AI) applications focused on biomedical imaging datasets. The course will cover the entire AI pipeline from image exploration and labeling to development and deployment of predictive Read More...

10/19/2022 - Speaker: Ron Germain, M.D., Ph.D. NIH Distinguished Investigator NIAID, NIH Dr. Germain received his Sc.B. and Sc.M. from Brown University in 1970 and his M.D. and Ph.D. from Harvard Read More...

04/07/2022 - Join Dr. Maryellen L. Giger at the April NCI Imaging and Informatics Community Webinar for a discussion on the development, validation,  database  needs, and ultimate future implementation of artificial intelligence (AI) in the clinical Read More...

08/17/2021 - Participants will learn how to develop artificial intelligence (AI) applications focused on biomedical imaging datasets. The course will cover the entire AI pipeline from image exploration and labeling to development and deployment of predictive Read More...

04/14/2021 - Registration: https://cbiit.webex.com/cbiit/onstage/g.php?MTID=ec198bc69667ba131397fb48e0c9b9708 Presenter: Christian Zinser PhD Head of Bioinformativs at Precigen Bioinformatics Germany Description: This presentation will give you Read More...

10/06/2020 - Participants will learn how to develop artificial intelligence (AI) applications focused on biomedical imaging datasets. The course will cover the entire AI pipeline from image exploration and labeling to development and deployment of predictive Read More...

04/23/2025 - Dr. Ruppin's research is focused on multi-disciplinary, algorithmic, computationally driven analysis of large-scale biomedical omics and clinical data, with an emphasis on AI and machine / deep learning approaches. Overall, it centers on three Read More...

11/21/2024 - Dear FNL colleagues,   It’s time once again for our last in 2024 Biotech Connector event!!   The Frederick National Laboratory for Cancer Research together with the Frederick County Chamber of Commerce organizes the quarterly Biotech Read More...

09/18/2024 - Frederick National Laboratory Science and Technology Group: Work in Progress Seminar Series presents:  “Modernization of Next Generation Sequencing Big Data Analysis Pipelines Leveraging NIH’s on-prem High Performance Computing Cluster … and Cloud.” Meeting ID: 225 592 603 654  Read More...

06/20/2024 - Clustered heat maps are widely used for visualizing patterns in molecular profiling data. But traditional, static heat maps have significant limitations when applied to large datasets (1000s of elements per axis). Presented in this Read More...

03/06/2024 - The NCI Cancer Diagnosis Program in the Division of Cancer Treatment and Diagnosis is hosting a workshop, “Digital Pathology Imaging (DPI) in Cancer Clinical Trials and Research.” This workshop will Read More...

Reproducibility in science means being able to generate the same experimental / analytical results with a high degree of reliability. This is necessary for research validation, scientific and public trust, innovation, and collaboration. Reproducibility is not Read More...

10/24/2023 - In this session, we will provide an overview of the Next-Generation Sequencing (NGS) capabilities and applications. We will present the workflows and analyses for Illumina short-read, PacBio, and Oxford Nanopore long-read sequencing on Frederick Read More...

01/10/2023 - Over the last two decades three major technologies have developed as the bed rock of how we understand living systems; genomics, including nucleic acid based molecular biology readouts, imaging from near-atomic resolution to whole Read More...

12/14/2021 - Speaker: Alisa Goldstein, Ph.D. Senior Investigator NCI, Division of Cancer Epidemiology and Genetics, Clinical Genetics Branch Dr. Alisa Goldstein is a Senior Investigator in NIH’s Division of Cancer Epidemiology and Genetics (DCEG), Read More...

09/30/2021 - This NIH-FDA sponsored workshop will bring together members of the scientific community to discuss the obstacles and opportunities associated with NGS and radiomics tool development, validation, and regulatory science. NCI presenters include NCI Director, Read More...

09/29/2021 - This NIH-FDA sponsored workshop will bring together members of the scientific community to discuss the obstacles and opportunities associated with NGS and radiomics tool development, validation, and regulatory science. NCI presenters include NCI Director, Read More...

04/21/2021 - Registration: https://cbiit.webex.com/cbiit/onstage/g.php?MTID=e51f19be5660107b4b92118dc48be1781 Presenter: Kevin Kendal PhD CEO of MacVector Description: This workshop will focus on the analysis of Next Read More...

04/21/2021 - Register Description: MacVector is a sequence analysis application for macOS computers that provides users with a variety of tools and functions to simplify the analysis, manipulation, assembly, and documentation of DNA and protein sequences. Read More...

01/14/2021 - Registration: https://cbiit.webex.com/cbiit/onstage/g.php?MTID=e968a58127acdb59b961e2ef13865c7ad Description: This workshop will focus on the analysis of Next Generation Sequencing (NGS) data using the Read More...

11/03/2020 - Register Dr. Christina Curtis is an Assistant Professor in the Departments of Medicine (Oncology) and Genetics in the School of Medicine at Stanford University where she leads the Cancer Computational and Systems Biology Group Read More...

05/01/2013 - Intended Audience: This day-long training course is intended for Users who want to apply Next Generation Sequencing methodologies for DNA-Seq, Methyl-Seq, small RNA-Seq, RNA-Seq and ChIP-Seq studies.  All analyses are done on the Genomatix Read More...

02/21/2024 - Science and Technology Group: Work in Progress Seminar Series Meeting ID: 287 867 275 591  Passcode: wrbFXg 

Objectives To explore Bioconductor, a repository for R packages related to biological data analysis. To learn about options for report generation with R: RMarkdown and Quarto. Introducing Bioconductor Bioconductor is both an open source project Read More...

09/28/2022 - We invite you to join us for the Neuro-Oncology Visiting Scholar Lecture scheduled for next week by Eytan Ruppin, M.D. Ph.D: Next Generation Transcriptomics-based Precision Oncology Eytan Ruppin received his M.D. Read More...

07/28/2021 - Register/Join During this month's NCI Cancer Research Data Commons (CRDC) Cancer Genomics Cloud (CGC)  webinar series, two Georgetown University staff members about leveraging the CGC in their  data science  courses and curriculum. Read More...

06/04/2021 - Speaker: Rangan Sreenivas Sukumar Distinguished Technologist Hewlett Packard Enterprise (HPE) Abstract: In March of 2020, the “Force for Good” pledge of intellectual property to fight COVID-19 brought into action HPE products, resources and expertise to Read More...

Go back up one directory to the unix_on_biowulf_2023_documents folder and then change into the SRR1553606 folder. cd .. cd SRR1553606 There are two next generation sequencing data files (fastq files) in this folder. Read More...

Go back up one directory to the unix_on_biowulf_2023_documents folder and then change into the SRR1553606 folder. cd .. cd SRR1553606 There are two next generation sequencing data files (fastq files) in this folder. Read More...

06/20/2023 - Dr. Weissleder will talk about a novel method for single extracellular vesicle analysis which allows multiplexing (MASEV). This has generated new insight into EV biology and clinical applications. For any questions, please contact Kelly Read More...

06/01/2022 - This is an NIH Director’s Lecture. The Director’s Lectures feature leading researchers from around the globe. Nominated by scientists and interest groups throughout NIH, the speakers are specifically approved by the NIH Read More...

07/15/2021 - Register Now Faculty: Michael Angelo, MD, PhD – Stanford University, Moonshot Cancer Atlas Moderator: Carsten Krieg, PhD – Medical University of South Carolina Target Audience This series will serve as an excellent resource for all stakeholders Read More...

02/27/2026 - This one hour and half hour online training will equip attendees with essential knowledge and skills for effective interactions with Large Language Model (LLM) AI chatbots. Explore the intricacies of prompt engineering and its Read More...

10/30/2025 - This one hour and half hour online training will equip attendees with essential knowledge and skills for effective interactions with Large Language Model (LLM) AI chatbots. Explore the intricacies of prompt engineering and its Read More...

06/04/2025 - This one hour and half hour online training will equip participants with essential knowledge and skills for effective interactions with Large Language Models (LLMs), such as ChatGPT. Explore the intricacies of prompt engineering and Read More...

02/27/2025 - NGS produces millions of sequences per sample and the challenge is to identify where in the genome each sequence came from. Fortunately, there are aligners that help scientists with this task. After this class, Read More...

02/25/2025 - Quality assessment may reveal low quality sequences and/or contaminations such as adapters in NGS data. Therefore, it is important to perform cleanup to ensure that the input for downstream analyses tools is of Read More...

02/20/2025 - This class will introduce the first step in analyzing NGS data using bulk RNA sequencing as an example. After attending, participants will be able to describe the file format in which NGS data is Read More...

01/28/2025 - This one hour and half hour online training will equip participants with essential knowledge and skills for effective interactions with Large Language Models (LLMs), such as ChatGPT. Explore the intricacies of prompt engineering and Read More...

11/26/2024 - Dr. Daniel Orringer received his M.D. from The Ohio State University, completed his residency in neurological surgery at the University of Michigan Health System, and fellowship training in neuro-oncology at the Massachusetts General-Brigham Read More...

11/06/2024 - Neuro-Oncology Branch Visiting Scholar Program Lecture

09/17/2024 - This one hour and half hour online training will equip participants with essential knowledge and skills for effective interactions with Large Language Models (LLMs), such as ChatGPT. Explore the intricacies of prompt engineering and Read More...

05/30/2024 - This 90-minute course equips participants with essential knowledge and skills for effective interactions with Large Language Models (LLMs), such as ChatGPT. Explore the intricacies of prompt engineering and its pivotal role in optimizing the Read More...

04/26/2024 - Dear Colleagues,    In this webinar, you'll get an introduction to WebMeV. WebMeV aims to democratize bioinformatics analysis for biological sciences researchers.   The maturation of many bioinformatics processes Read More...

01/24/2024 - This 90-minute course equips participants with essential knowledge and skills for effective interactions with Large Language Models (LLMs), such as ChatGPT. Explore the intricacies of prompt engineering and its pivotal role in optimizing the Read More...

After the distance matrix has been calculated, it is time to perform the actual clustering and again, various approaches can be used to generate clusters. The following resources are good for learning about the variouse Read More...

After the distance matrix has been calculated, it is time to perform the actual clustering and again, various approaches can be used to generate clusters. The following resources are good for learning about the variouse Read More...

08/24/2022 - Precision oncology has made significant advances, mainly by targeting actionable mutations and fusion events involving cancer driver genes. Aiming to expand treatment opportunities, recent studies have begun to explore the utility of tumor transcriptome Read More...

07/28/2022 - This seminar series showcases research from different Cancer Moonshot initiatives that support the 10 recommendations of the  Blue Ribbon Panel  report. These presentations will inform the community about the progress of Cancer Moonshot–funded projects, Read More...

06/29/2022 - During this webinar, Computational Biologist Dr. Eytan Ruppin will present on “SELECT,” a computational approach that aims to identify clinically relevant synthetic lethal interactions, thereby harnessing them to predict patient response to cancer therapy Read More...

01/28/2022 - Geneious Prime is a comprehensive software suite of molecular biology and NGS analysis tools. It is built to be highly visual, easy to use, and collaborative. Tools include primer design and molecular cloning, chromatogram Read More...

11/18/2021 - Presenter: Greg Thurber, Ph.D. University of Michigan

01/23/2020 - Experimental Design Considerations in Variant Analysis Germline vs Somatic WGS vs WES Sample sizes and statistical power WGS/WES Pipelines at NIH Pipeline performance Using Pipeliner for internal and external data Variant QC, Annotation Read More...

04/09/2019 - DNAnexus provides a secure cloud based platform for the analysis, storage and sharing of many different types of genomic data. CCR has recently established a Pilot program to enable CCR researchers to use this Read More...

06/26/2018 - DNAnexus provides a secure cloud based platform for the analysis, storage and sharing of many different types of genomic data. A point-and-click web environment provides ready access to powerful tools for the analysis, integration Read More...

05/07/2013 -   This 2 hour seminar will be an interactive discussion and demonstration of the types of applications and work-flows that can be performed on deep sequencing data generated by the latest instruments from Illumina, Life Technologies ( Read More...

02/26/2013 -   Comparison Study of NGS SNP Detection Tools Brief background and introduction for the current status of SNP detection field and each of the selected tools to be compared Description of our benchmark exome-seq data Read More...

Lesson 3 recording

05/12/2023 - Are you familiar with the bioinformatics tools and databases Enrichr, Harmonizome, BioJupies, and ARCHS4, developed by the Ma’ayan Lab? In this webinar, Dr. Avi Ma’ayan describes two new Read More...

12/02/2026 - Partek Flow is a point-and-click platform for building analysis workflows for Next Generation Sequences (NGS), including DNA, bulk and single-cell RNA, spatial transcriptomics, ATAC, and ChIP, helping scientists avoid the steep learning curve of Read More...

10/14/2026 - Partek Flow is a point-and-click platform for building analysis workflows for Next Generation Sequences (NGS), including DNA, bulk and single-cell RNA, spatial transcriptomics, ATAC, and ChIP, helping scientists avoid the steep learning curve of Read More...

08/19/2026 - Partek Flow is a point-and-click platform for building analysis workflows for Next Generation Sequences (NGS), including DNA, bulk and single-cell RNA, spatial transcriptomics, ATAC, and ChIP, helping scientists avoid the steep learning curve of Read More...

06/18/2026 - Partek Flow is a point-and-click platform for building analysis workflows for Next Generation Sequences (NGS), including DNA, bulk and single-cell RNA, spatial transcriptomics, ATAC, and ChIP, helping scientists avoid the steep learning curve of Read More...

02/18/2026 - Partek Flow is a point-and-click platform for building analysis workflows for Next Generation Sequences (NGS), including DNA, bulk and single-cell RNA, spatial transcriptomics, ATAC, and ChIP, helping scientists avoid the steep learning curve of Read More...