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Search Results for: NCI-60 cell lines

Total Results Found: 280

Total Results Found: 280

Past Seminars

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Confocal

2024 Date: Tuesday, October 15, 2024 Time and Location: 11 am EST, ZOOM (INVITATION BY LMIG LIST SERVER) Speaker: Dr. Diego Presman (U Buenos Aires) Title: “Insights on Glucocorticoid Receptor Activity Through Live Cell Imaging” Summary: Eucaryotic transcription factors ( Read More...

NIH Stem Cell Unit
Bethesda, MD

Trans NIH Facility

The Stem Cell Unit (SCU) has established a database to which hESC lines, adult stem cells and induced pluripotent stem (iPS) cells may be directly compared. These data give scientists the information they need when Read More...

Publications

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Confocal

2024 L. Balagopalan, T. Moreno, H. Qin, B. C. Angeles, T. Kondo, J. Yi, K. M. McIntire, N. Alvinez, S. Pallikkuth, M. E. Lee, H. Yamane, A. D. Tran, P. Youkharibache, R. E. Cachau, N. Taylor, Read More...

NCI Genomics and Pharmacology Facility
Bethesda, MD

Core Facility

The Genomics and Pharmacology Facility is part of the NCI's Center for Cancer Research (CCR), within the Developmental Therapeutics Branch. Its mission is to manage and assess molecular interaction data obtained through multiple platforms, increase Read More...

Molecular Targets Database and Tools
Rockville, MD

Repositories

Trans NIH Facility

Thousands of molecular targets have been measured in the NCI panel of 60 human tumor cell lines. Measurements include protein levels, RNA measurements, mutation status, and enzyme activity levels. You can choose to search for a Read More...

The CCBR Single-cell RNA-seq Workflow on NIDAP

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Bioinformatics

05/29/2024 - This talk will cover a scRNA-seq workflow available to NCI researchers on NIDAP. NIDAP, the NIH Integrated Data Analysis Platform, is a cloud-based and collaborative data aggregation and analysis platform that hosts user-friendly bioinformatics Read More...

Single Cell Data Analysis in Partek Flow

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Bioinformatics

03/08/2023 - Partek software provides a singular web based point and click environment for analyzing and visualizing high dimensional multi-omics sequencing data, making bioinformatics easily accessible to all researchers.  Partek Flow software is available to NCI Read More...

Genomic Data Commons Single Cell RNA-Seq Support

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Bioinformatics

09/27/2021 - The NCI Genomic Data Commons’ (GDC) September webinar will introduce cancer researchers and bioinformaticians to the GDC's single-cell RNA-Seq (scRNA-Seq) data workflow. Single cell sequencing is a powerful platform for studying tumor heterogeneity Read More...

Single Cell RNA-Seq Data Analysis in Partek Flow

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Bioinformatics

06/30/2021 - Registration is required to join this event. If you have not registered, please do so now. Register Speaker: Uchenna Emechebe, Ph.D., Field Application Scientist, Partek Incorporated. Partek® Flow® bioinformatics software which is available Read More...

NCI Molecular Cytogenetics Core Facility
Frederick, MD

Core Facility

Molecular Cytogenetics Core Facility facilitates the assessment of structural and numerical genomic changes in pre-cancer and cancer research models. This core provides comprehensive support for the cytogenetic analysis of cells from human and research animal Read More...

CCR Single Cell Analysis Facility (SCAF)
Bethesda, MD

Core Facility

The rapid advancement of single-cell technology has provided new powerful tools to answer many biological questions, such as identifying new or rare cell populations and characterizing the complexities of tumor heterogeneity. Realizing the great potential Read More...

NCI LASP Genome Modification Core (GMC)
Frederick, MD

Core Facility

NCI LASP Genome Modification Core (GMC) is a CCR-dedicated facility that provides advice, training, and reagents to NCI scientists seeking to utilize CRISPR and other nucleases to generate genome modifications in primary cells, cell lines, Read More...

Single-cell RNA-Seq Analysis on NIDAP

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Bioinformatics

10/28/2021 - Single-cell RNA sequencing (scRNA-seq) is a relatively new and powerful method in genomics, which enables the interrogation of whole single cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a basic scRNA-seq workflow, Read More...

Single-cell RNA-Seq Analysis on NIDAP

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Bioinformatics

10/14/2021 - Single-cell RNA sequencing (scRNA-seq) is a relatively new and powerful method in genomics, which enables the interrogation of whole single cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a basic scRNA-seq workflow, Read More...

Single-cell RNA-Seq Analysis on NIDAP

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Bioinformatics

09/30/2021 - Single-cell RNA sequencing (scRNA-seq) is a relatively new and powerful method in genomics, which enables the interrogation of whole single cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a basic scRNA-seq workflow, Read More...

Single-cell RNA-Seq Analysis on NIDAP

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Bioinformatics

09/16/2021 - Single-cell RNA sequencing (scRNA-seq) is a relatively new and powerful method in genomics, which enables the interrogation of whole single cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a basic scRNA-seq workflow, Read More...

Single-cell RNA-Seq Analysis on NIDAP

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Bioinformatics

08/26/2021 - Single-cell RNA sequencing (scRNA-seq) is a relatively new and powerful method in genomics, which enables the interrogation of whole single cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a basic scRNA-seq workflow, Read More...

Single-cell RNA-Seq Analysis on NIDAP

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Bioinformatics

08/12/2021 - Single-cell RNA sequencing (scRNA-seq) is a relatively new and powerful method in genomics, which enables the interrogation of whole single cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a basic scRNA-seq workflow, Read More...

Single-cell RNA-Seq Analysis on NIDAP

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Bioinformatics

07/29/2021 - Single-cell RNA sequencing (scRNA-seq) is a relatively new and powerful method in genomics, which enables the interrogation of whole single cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a basic scRNA-seq workflow, Read More...

Single-cell RNA-Seq Analysis on NIDAP

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Bioinformatics

07/15/2021 - Single-cell RNA sequencing (scRNA-seq) is a relatively new and powerful method in genomics, which enables the interrogation of whole single cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a basic scRNA-seq workflow, Read More...

Single-cell RNA-Seq Analysis on NIDAP

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Bioinformatics

06/24/2021 - Single-cell RNA sequencing (scRNA-seq) is a relatively new and powerful method in genomics, which enables the interrogation of whole single cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a basic scRNA-seq workflow, Read More...

Single-cell RNA-Seq Analysis on NIDAP

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Bioinformatics

06/10/2021 - Single-cell RNA sequencing (scRNA-seq) is a relatively new and powerful method in genomics, which enables the interrogation of whole single cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a basic scRNA-seq workflow, Read More...

Single-cell RNA-Seq Analysis on NIDAP

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Bioinformatics

05/20/2021 - Single-cell RNA sequencing (scRNA-seq) is a relatively new and powerful method in genomics, which enables the interrogation of whole single cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a basic scRNA-seq workflow, Read More...

Single-cell RNA-Seq Analysis on NIDAP

Web Page

Bioinformatics

05/06/2021 - Single-cell RNA sequencing (scRNA-seq) is a relatively new and powerful method in genomics, which enables the interrogation of whole single cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a basic scRNA-seq workflow, Read More...

Single-cell RNA-Seq Analysis on NIDAP

Web Page

Bioinformatics

04/22/2021 - Single-cell RNA sequencing (scRNA-seq) is a relatively new and powerful method in genomics, which enables the interrogation of whole single cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a basic scRNA-seq workflow, Read More...

Single-Cell RNA-Seq Analysis on NIDAP

Web Page

Bioinformatics

04/08/2021 - Single-cell RNA sequencing (scRNA-seq) is a relatively new and powerful method in genomics, which enables the interrogation of whole single cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a basic scRNA-seq workflow, Read More...

Single-Cell RNA-Seq Analysis on NIDAP

Web Page

Bioinformatics

03/18/2021 - Single-cell RNA sequencing (scRNA-seq) is a relatively new and powerful method in genomics, which enables the interrogation of whole single cellular transcriptomes. The CCR Collaborative Bioinformatics Resource (CCBR) has implemented a basic scRNA-seq workflow, Read More...

NCI Patient-Derived Models Repository (PDMR)
Bethesda, MD

Collaborative

Repositories

The National Cancer Institute (NCI) is developing a national repository of Patient-Derived Models (PDMs) comprised of patient-derived xenografts (PDXs), patient-derived organoids (PDOrg), and in vitro patient-derived tumor cell cultures (PDCs) and cancer-associated fibroblasts (CAFs). These Read More...

NCI Research Flow Facility
NCI-Bethesda, MD

Collaborative

The NCI Research Flow Facility provides cell sorting and benchtop flow cytometry services to NCI investigators. Services are program-specific and are not available to all NCI or NIH investigators. Please inquire as to availability. Established Read More...

NCI High-Throughput Imaging Facility (HiTIF)
Bethesda, MD

Collaborative

The NCI High-Throughput Imaging Facility (HiTIF) works in a collaborative fashion with NCI/NIH Investigators by providing them with the necessary expertise, instrumentation, and software to develop and execute advanced High-Throughput Imaging (HTI) assays. These Read More...

NCI at Frederick Central Repository
Frederick, MD

Collaborative

Repositories

The Central Repository provides the research community at the NCI with various cryogenic services, including low-temperature storage from +4° C to -196° C, controlled-rate freezing, computerized inventory and distribution of samples. The Central Repository is operated Read More...

NCI CCR-Frederick Flow Cytometry Core Facility
Frederick, MD

Core Facility

The CCR-Frederick Flow Cytometry Core Facility provides research support to the Frederick-CCR community, including cytometry analysis and sorting services, instrument maintenance, new user training, and technical consultation. Typical Assays Performed by Core Instruments Immunophenotyping of Read More...

NCI Specimen Resource Locator (SRL)
ROCKVILLE, MD

Repositories

Trans NIH Facility

The Specimen Resource Locator (SRL) is a biospecimen resource database designed to help researchers locate resources that may have the samples needed for their investigational use. This publicly searchable database includes information about biospecimen banks Read More...

NCI LASP Gnotobiotics Facility (GF)
Frederick, MD

Core Facility

The Laboratory Animal Sciences Program (LASP) of the Frederick National Laboratory operates a Gnotobiotics Facility (GF) to support research focused on the role of microbiota in cancer inflammation, pathogenesis, and treatment response. The GF can Read More...

NCI Center for Structural Biology: Protein Technology Core
Frederick, MD

Collaborative

The primary objective of the Protein Technology Core (PTC) is to establish an experimental screening pipeline for single-domain antibodies termed nanobodies. Nanobodies are antibody fragments consisting of a single monomeric variable antibody domain. The PTC, Read More...

NCI LASP Mouse Modeling & Cryopreservation (MMC)
Frederick, MD

Core Facility

Repositories

The Mouse Modeling Core assists NIH investigators by generating and preserving genetically-engineered mouse strains. Services include scientific consultation, gene-targeting in mouse embryonic stem cells, micro-injection of nucleic acids, proteins, or ES cells into mouse embryos, Read More...

Molecular Modeling Core (Laboratory of Cell Biology)
Bethesda, MD

Collaborative

The CCR Molecular Modeling Core, under the direction of Dr. Stewart Durell, was established to provide a convenient way for experimentalists to take advantage of molecular modeling and computational biology. In the framework of consultations, Read More...

NCI CCR Clinical Research Correlatives Core
Bethesda, MD

Collaborative

The NCI Clinical Research Correlatives Core provides non-CLIA-certified spectral flow cytometric assays to support clinical trials conducted in the CCR. The core specializes in immunophenotyping and immune monitoring assays. Established Technologies Spectral flow cytometry (Cytek), Read More...

NCI Cloud Resources
Rockville, MD

Collaborative

Repositories

The NCI Cloud Resources are components of the NCI Cancer Research Data Commons (CRDC) that bring data and computational power together to enable cancer research and discovery. These cloud-based platforms eliminate the need for researchers Read More...

NCI Clinical Pharmacology Program (CPP)
Bethesda, MD

Core Facility

The CPP is directly responsible for the pharmacokinetic (PK) analysis of numerous Phase I and II clinical trials conducted within the NCI. In addition, the CPP provides direct PK support for many studies performed elsewhere Read More...

NCI Clinical Support Laboratory: Flow Cytometry Section
Frederick, MD

Core Facility

Clinical Support Laboratory – Flow Cytometry Section is a laboratory specializing in providing immunophenotyping support of NCI intramural clinical trials, though assessments may also be performed using cells from Non-human primates and other species. The CSL Read More...

NCI LASP Animal Research Technology Support (ARTS)
Frederick, MD

Core Facility

NCI LASP Animal Research Technology Support (ARTS) provides customized technical support for basic and translational animal-based research to the scientific community. We offer a wide array of services ranging from expert colony management to the Read More...

Getting Started with scRNA-Seq Seminar Series: Contacts

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Bioinformatics

Who can you contact with questions? NCI CCR Single Cell Analysis Facility (SCAF) provides single cell support to NCI-CCR Researchers. NCI CCR Bioinformatics Training and Education Program (BTEP) provides bioinformatics training support. Contact BTEP via Read More...

Finding Neighborhoods in the Land of Spatial Omics

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Bioinformatics

04/23/2024 - Join Dr. Kai Tan of the Children’s Hospital of Philadelphia as he discusses his cutting-edge technology, CytoCommunity, for the supervised and unsupervised discovery of tissue cellular neighborhoods. CytoCommunity offers a powerful Read More...

DCTD Tumor Repository
Frederick, MD

Repositories

Trans NIH Facility

The Developmental Therapeutics Program (DTP) within NCI's Division of Cancer Treatment and Diagnostics (DCTD), has maintained a low temperature repository of transplantable in vivo-derived tumors and in vitro-established tumor cell lines from various species. This Read More...

NCI Advanced Biomedical Computational Science (ABCS)
Frederick, MD

Core Facility

The Advanced Biomedical Computational Sciences (ABCS) group provides technology development, scientific consultation, collaboration and training, research, software development, and high-performance computing support. ABCS encompasses specialized groups focusing on machine learning applied to the interpretation of 2 Read More...

NCI Center for Advanced Preclinical Research (CAPR)
Frederick, MD

Collaborative

The Center for Advanced Preclinical Research (CAPR) specializes in evaluating the efficacy of preclinical compounds, existing drugs, or biologics (therapeutics) in genetically engineered mouse models, GEM-derived allograft (GDA) models, or patient-derived mouse xenografts (PDX). We Read More...

NCI Genetics Branch: OMICS Technology Facility
Bethesda, MD

Collaborative

Our operational objectives are to provide state-of-the-art OMICS technologies in support of the Genetics Branch (GB) investigators and collaborators. Research Services Wet Lab Single cell isolation from fresh, frozen, and FFPE tissue, DNA/RNA extractions Read More...

NCI Proteomic Data Commons (PDC)
Rockville, MD

Collaborative

Repositories

Proteomic Data Common (PDC) represents the NCI’s largest public repository of proteogenomic comprehensive tumor datasets, essentially a Proteogenomic Cancer Atlas. It was developed to advance our understanding of how proteins help shape the risk, Read More...

NCI Synthetic Biologics Core
Frederick, MD

Core Facility

The research conducted within the Synthetic Biologics Core (SBC) Facility has a dual role: Generate chemical biology tools and drug candidates for molecular targets identified by NCI research groups, Develop novel effective methods and tools Read More...

NCI LASP Small Animal Imaging Program (SAIP)
Frederick, MD

Core Facility

The function of the SAIP is to collaborate with NCI investigators in the development of mouse models, new molecular imaging probes for early detection and therapy, monitor tumors in vivo, and perform drug efficacy studies Read More...

NCI LASP Animal Diagnostic Lab (ADL)
Frederick, MD

Core Facility

The Animal Diagnostic Laboratory (ADL) provides a full range of diagnostic capabilities, including microbiological cultures on various culture medium, microscopic screening for parasites such as mites and pinworms, molecular detection of pathogens, serological evaluation of Read More...

NCI Genomic Data Commons (GDC)
Bethesda, MD

Collaborative

Repositories

The NCI Genomic Data Commons (GDC) was established by the NCI Center for Cancer Genomics (CCG) to support the receipt, harmonization, distribution, and analysis of genomic and clinical data from cancer research programs. The GDC Read More...

NCI Medicinal Chemistry Accelerator (MCA)
Frederick, MD

Collaborative

The Medicinal Chemistry Accelerator (MCA) is a collaborative CCR resource that supports investigators in developing small molecule inhibitors for anticancer drug candidates. While CCR and NCATS have infrastructure to identify initial “hits” through high-throughput screening, Read More...

NCI SAXS Facility
Frederick, MD

Collaborative

In order to meet increasing demands from both NIH intramural and extramural communities for access to a small angle X-ray scattering (SAXS) resource, the Center for Cancer Research (CCR) under the leadership of Drs. Jeffrey Read More...

NCI Center for Structural Biology: Crystallization Facility
Frederick, MD

Collaborative

The Crystallization Facility provides an automated environment for setting up crystallization experiments in a high-throughput format, storing the resulting plates under controlled conditions, and monitoring the status of prepared droplets remotely. The Facility is in Read More...

BTEP course: Learning Objectives

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Bioinformatics

After this class, participants will Become familiar analyzing single cell RNA sequencing data using Partek Flow including Importing of data into a Partek Flow project QA/QC, filtering, and normalizing of single cell RNA data Read More...

Data Used in Cellular Therapies

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Bioinformatics

01/16/2024 - To register to attend, you must log in or create a free SITC Cancer Immunotherapy CONNECT account. It’s your last chance to register and learn about the cutting edge of computational immuno-oncology through Read More...

Capabilities of the NIDAP platform for Transcriptomic Analysis

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Bioinformatics

12/14/2023 - NIDAP , the NIH Integrated Data Analysis Platform, is a cloud-based, collaborative data aggregation and analysis platform that hosts user-friendly bioinformatics workflows and other component analysis and visualization tools. The NCI CCR Collaborative Bioinformatics Resource ( Read More...

2023 Distinguished Speakers Seminar Series

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Bioinformatics

March 30, 1 - 2 PM Building a Mind for Cancer Trey Ideker, Ph.D. University of California San Diego Professor, Department of Medicine Adjunct Professor, Departments of Bioengineering and Computer Science Co-Director, Bioinformatics and Systems Biology PhD Read More...

NIH Spatial Transcriptomics Showcase

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Bioinformatics

11/01/2022 - Join us to learn how Visium Spatial and Xenium In Situ platforms from 10x Genomics can help you push the boundaries of your research. Uncover molecular insights, dissect cell-type differences, investigate the adaptive immune Read More...

Antibody Characterization Laboratory (ACL)
Frederick, MD

Collaborative

The Antibody Characterization Laboratory (ACL) is the laboratory responsible for the development of well-characterized monoclonal antibody reagents. The NCI’s Office of Cancer Clinical Proteomics Research funds ACL as a resource to the entire cancer Read More...

Laboratory of Genome Integrity (LGI): Flow Cytometry Core
Bethesda, MD

Core Facility

The Flow Cytometry Core (LGI) offers established technologies to support studies using flow cytometry and cell sorting. Established Technologies Applications that run on FACS Caliburs include: Immunophenotyping (up to 4-color), Intracellular markers, including cytokines and Read More...

NHLBI Transgenic Core
Bethesda, MD

Core Facility

Trans NIH Facility

The NHLBI Transgenic Core’s main mission is to keep up with the latest advancements in genome engineering technologies and to provide state-of-the-art services to assist NIH scientists in generating genetically engineered animal models. In Read More...

Biological Products Core (AIDS and Cancer Virus Program)
Frederick, Maryland

Core Facility

Repositories

The Biological Products Core provides the AIDS research community with high-quality purified preparations of various strains of Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV), economically prepared by leveraging the economy of scale. Materials Read More...

The Human Tumor Atlas Network and HTAN Data Portal

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Bioinformatics

03/19/2025 - Please note: Registration is required to get the Meeting Link for this event. Please pre-register. The Human Tumor Atlas Network (HTAN) is a National Cancer Institute (NCI)-funded initiative to construct 3-dimensional atlases of Read More...

Bulk RNA Sequencing Analysis using Partek Flow

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Bioinformatics

11/19/2024 - Partek Flow enables scientists to construct analysis workflows for multi-omics sequencing data including DNA, bulk and single cell RNA, spatial transcriptomics, ATAC and ChIP. It is a point-and-click software hosted on Biowulf, the NIH Read More...

Partek Flow Quick Start Guide

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Bioinformatics

Partek Flow enables scientists to build comprehensive workflows for analyzing multi-omics high throughput sequencing data including DNA and variant calling, bulk and single cell modalities for RNA, ChIP, and ATAC, spatial transcriptomics, CITE, and immune Read More...

BTEP course: Partek Flow at NIH

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Bioinformatics

Accessing Partek Flow at NIH and tips for data transfer Learning objectives After consulting this guide, participants will Know how to access Partek Flow at NIH. Be able to transfer data from NCI CCR Sequencing Read More...

BTEP course: Course overview

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Bioinformatics

Course Overview Partek Flow is a start-to-finish solution for analyzing high dimensional multi-omics sequencing data. It is a point-and-click software and is suitable for those who wish to avoid the steep learning curve associated with Read More...

BTEP course: Instructions for accessing Partek Flow

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Bioinformatics

NCI researchers can find instructions for accessing Partek Flow at https://bioinformatics.ccr.cancer.gov/btep/partek-flow-bulk-and-single-cell-rna-seq-data-analysis/ . But the things needed are A Biowulf (The High Performance Computing cluster) account — see here for information about Read More...

BTEP course: Instructions for accessing Partek Flow

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Bioinformatics

NCI researchers can find instructions for accessing Partek Flow at https://bioinformatics.ccr.cancer.gov/btep/partek-flow-bulk-and-single-cell-rna-seq-data-analysis/ . But the things needed are A Biowulf (The High Performance Computing cluster) account — see here for information about Read More...

Next generation transcriptomics-based precision oncology

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Bioinformatics

08/24/2022 - Precision oncology has made significant advances, mainly by targeting actionable mutations and fusion events involving cancer driver genes. Aiming to expand treatment opportunities, recent studies have begun to explore the utility of tumor transcriptome Read More...

Next Generation Transcriptomics-based Precision Oncology

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Bioinformatics

06/29/2022 - During this webinar, Computational Biologist Dr. Eytan Ruppin will present on “SELECT,” a computational approach that aims to identify clinically relevant synthetic lethal interactions, thereby harnessing them to predict patient response to cancer therapy Read More...

Explore ‘Omics Datasets Using Land Explorer for IPA

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Bioinformatics

05/19/2021 - Register Description: IPA’s Analysis Match Explorer was launched in March 2020 and this upgrade is being evaluated for purchase by NCI. NCI scientists will have no-charge access to Analysis Match Explorer for a limited Read More...

DTP Repository of Chemical Agents
Rockville, MD

Repositories

Trans NIH Facility

DTP maintains a repository of synthetic compounds and pure natural products that are available to investigators for non-clinical research purposes. The Repository collection is a uniquely diverse set of more than 200,000 compounds that have been Read More...

Clinical Support Laboratory
Frederick, MD

Core Facility

The Clinical Support Laboratory offers processing, tracking, and testing of a broad range of clinical samples. Support can begin at the early stages of clinical trial development to aid in developing a comprehensive strategy for Read More...

Clinical Support Laboratory –Cellular Immunology
Frederick, MD

Core Facility

Clinical Support Laboratory – Cellular Immunology offers a spectrum of bioassays to assess cellular responses to antigens and mitogens including ELISPOT, cytotoxicity assays, and proliferation assays. Established Technologies Elispot Assays, Dual or Triple Color Fluorospot Assays, Read More...

Biopharmaceutical Development Program (BDP)
Frederick, MD

Collaborative

The Biopharmaceutical Development Program (BDP) provides resources for the development of investigational biological agents. The BDP supports feasibility through development and Phase I/II cGMP manufacturing plus regulatory documentation.The BDP was established in 1993. We Read More...

Antibody Engineering Program
Bethesda, MD

Collaborative

The Antibody Engineering Program (AEP) is located at the Laboratory of Molecular Biology, which is part of the Center for Cancer Research (CCR), an intramural program at the National Cancer Institute (NCI). AEP focuses on Read More...

September 2021

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CREx News & Updates September 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGLIGHTS Learn more about services from the CCR Read More...

Antibody​​ Engineering Program

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The Antibody Engineering Program (AEP) is part of the Center for Cancer Research (CCR) at the National Cancer Institute (NCI). The program focuses on generating therapeutic antibodies by phage display technology, including human antibodies and Read More...

Bioinformatics Resources

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Discover expert help with analysis, processing applications, and licensed software packages.

April 2023 Newsletter

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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New Resources on CREx Interested in imaging large scale biological samples?  Volume electron microscopy allows for Read More...

Bloomington Drosophila Stock Center
Bloomington, IN

Repositories

Trans NIH Facility

The Bloomington Drosophila Stock Center (BDSC) collects, maintains, and distributes genetically defined strains of Drosophila melanogaster for research and education. The BDSC supports a large, worldwide community of scientists using Drosophila as a model organism Read More...

Class Documents

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Bioinformatics

Most BTEP courses include detailed course materials including lesson content, additional resources, and lesson associated data. These course materials are listed here so that learners can easily return to and review concepts taught in class Read More...

Bulletins

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Bioinformatics

This archive contains past and present issues of the  BTEP BioInformatics Bulletin. The BTEP Bioinformatics Bulletin features select upcoming bioinformatics events offered across NIH and is distributed monthly via email to the Center Read More...

Contacts

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Bioinformatics

General questions or comments about the BTEP program or classes should be addressed to: NCIBTEP@nih.gov Desiree Tillo, Ph.D . Staff Scientist desiree.tillo@nih.gov I have a broad research background in bioinformatics Read More...

The Advanced Biomedical Computational Science (ABCS) Group

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Bioinformatics

The Advanced Biomedical Computational Science (ABCS) group focuses on applications of bioinformatics, computational and data science, and artificial intelligence to support NCI researchers. ABCS provides: • Subject matter expertise in genomics, proteomics, and imaging. • Machine learning/ Read More...

Learning R with BTEP

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Bioinformatics

R is both a computational language and open-source environment for statistical computing and graphics. While R programming was ranked 20 th in popularity when compared with other programming languages in December 2023, it remains a favorite among Read More...

Bioinformatics for Beginners 2022: Syllabus

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Bioinformatics

Syllabus for “Bioinformatics for Beginners" Instructors: Co-Instructors: To participate in these courses, you need a computer, reliable internet connection and a web browser. All classes and help sessions will be held online. This class Read More...

Bulk RNA-Seq Data Analysis in Partek Flow

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Bioinformatics

06/23/2021 - Registration is required to join this event. If you have not registered, please do so now. Register Speaker: Uchenna Emechebe, Ph.D., Field Application Scientist, Partek Incorporated Partek® Flow® bioinformatics software which is available Read More...

CCR Protein Characterization Laboratory (PCL)
Frederick, MD

Core Facility

Protein Characterization Laboratory (PCL) offers various technologies to CCR investigators to characterize proteins and metabolites. The laboratory develops and applies state-of-the-art analytical technologies, primarily mass spectrometry, liquid chromatography, and Surface Plasmon Resonance (SPR), to advance Read More...

CCR Protein Expression Laboratory (PEL)
Frederick, Maryland

Core Facility

The Protein Expression Laboratory produces proteins to help CCR investigators achieve their research goals with the lowest possible cost in the shortest time. PEL is operated by Leidos Biomedical Research Inc. on behalf of NCI Read More...

Comparative Oncology Program (COP)
Bethesda, MD

Collaborative

The COP evaluates novel therapies in pet dogs with cancer to improve outcomes for human patients and established the Comparative Oncology Trial Consortium (COTC), a collaborative effort of NCI and extramural comparative oncology centers at 24 Read More...

The CCR Microscopy Core
Bethesda, MARYLAND

Core Facility

The CCR Microscopy Core provides NCI investigators access to state-of-the-art imaging tools and techniques, including light sheet fluorescence, high-resolution confocal, multi-photon, and super-resolution microscopy. The mission of the CCR Microscopy Core Facility is to support Read More...

CCR Building 41 Flow Cytometry Core
Bethesda, MD

Core Facility

The CCR Building 41 Flow Cytometry Core is a full-service facility within the Center for Cancer Research that supports over 150 users representing 26 laboratories. The Core Facility provides instrument and software training, technical expertise, assay development, and Read More...

CCR Spatial Imaging Technology Resource (SpITR)
Bethesda, MD

Collaborative

The Spatial Imaging Technology Resource (formerly the Nanoscale Protein Analysis Section of the Collaborative Protein Technology Resource or CPTR) provides expertise and service in state-of-the-art protein analysis technologies to advance CCR research in basic discovery Read More...

CCR Genomics Core
Bethesda, MD

Core Facility

The CCR Genomics Core is located in Building 41 on the NIH Bethesda campus. The primary goal of the Core is to provide investigators from CCR/NCI and other NIH Institutes access to genomic technologies and Read More...

CCR Sequencing Facility
Frederick, MD

Core Facility

The introduction of DNA sequencing instruments capable of producing millions of DNA sequence reads in a single run has profoundly altered the landscape of genetics and cancer biology. Complex questions can now be answered at Read More...

CLIA Molecular Diagnostics Laboratory
Frederick, Maryland

Core Facility

CLIA-Certified Technologies Offered: Fragment Analysis for Micro-satellite Instability Detection, Pharmacoscan Array for Pharmacogenomics, Mutation Detection for PCR and Sanger Sequencing, DNA extraction from whole blood, saliva, FFPE tissues, buccal swabs, nails, hair, PBMCs, buffy coats, Read More...

January 2023 Newsletter

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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New Resources on CREx NIH NeuroBioBank (NBB) The NBB provides researchers with access to human post-mortem brain tissue Read More...

Front page

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Our Mission The Office of Science and Technology Resources (OSTR) catalyzes the advancement of cancer research through making innovative technologies and scientific resources accessible to scientists at the Center for Cancer Research (CCR). OSTR develops Read More...

Bioinformatics Resources

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Discover expert help with analysis, processing applications, and licensed software packages.

Emerging Technologies

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Many established and emerging technologies are available to CCR scientists.  This technology-rich environment makes the CCR a unique place to conduct scientific research.  Through the OSTR, the CCR continues to find Read More...

October Newsletter 2022-3

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October 6, 2022 crex.nih.gov CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Science & Technology Seminars and Training Events Upcoming Seminars and Educational Opportunities The following Read More...

NIH Intramural Sequencing Center (NISC)
Rockville, MD

Trans NIH Facility

NISC’s role within NHGRI, and more broadly across NIH, aims to advance genome sequencing and its many applications, with a goal not simply to produce sequence data, but to produce the infrastructure required to Read More...

May 2022 Newsletter

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CREx News & Updates May 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Click below to learn how easy it is to navigate the CREx platform. These short videos will Read More...

February 2022 Newsletter

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CREx News & Updates February 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight ORS Division of Veterinary Resources (DVR) DVR is the central NIH lab animal support program Read More...

June 2022 Newsletter

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CREx News & Updates June 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Click below to learn how easy it is to navigate the CREx platform. These short videos will Read More...

EIB Confocal Microscopy Facility
Bethesda, MD

Collaborative

As a multi-user facility, the different instruments provide a wide range of imaging modes for EIB scientists, from standard immunohistochemistry, through brightfield and wide-field epifluorescence imaging, to highly complex live cell confocal microscopy and super-resolution Read More...

NIH Intramural CryoEM Consortium (NICE)
Bethesda, MD

Trans NIH Facility

NIH Intramural CryoEM Consortium (NICE) serves intramural investigators in all NIH IC’s. NICE provides access to state-of-the-art Titan Krios cryo-electron microscopes for atomic-resolution structure determination of protein, macromolecular complexes, membrane receptors, cellular organelles, and Read More...

10X Genomics

Web Page

[embed]https://youtu.be/yTl1Q0D7aZ0[/embed] 10x Genomics' supports multiple cancer research areas from single nucleotide and structural variant detection to single cell whole transcriptome gene expression analysis of thousands of individual Read More...

Animal Resource Program (ARP)
Bethesda, MD

Core Facility

The CCR Animal Resource Program (ARP) plans, develops, and coordinates laboratory animal resources for CCR’s research programs. We also provide training, imaging, and technology development in support of moving basic discoveries to the clinic. Read More...

July 2021

Web Page

CREx News & Updates July 2021   Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGHLIGHTS Learn more about services from the NHLBI Read More...

Clinical Pharmacology Program (CPP): Pharmacogenetics Section
Bethesda, MD

Core Facility

The Pharmacogenetics Core is responsible for correlating outcome observations (toxicity, efficacy, survival, PK/PD) with genetic variants (germline or somatic) to identify key genetic determinants and biomarkers that predict response to specific treatments. We also Read More...

All Scientific Resources

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Cores & Facilities From centralized laboratories to collaborative resources and technologies available to CCR Investigators. NCI Cores Centralized laboratories providing broad access to cutting-edge technologies and specialized expertise. Browse NCI Cores Collaborative Resources are technologies and Read More...

CCR Optical Microscopy and Analysis Lab (OMAL)
Frederick, MD

Core Facility

OMAL focuses its research and development activities to quantitatively understand the molecular basis of three-dimensional (3D) cell organization, motility, invasion, and differentiation using fixed samples and live, 3D tissue culture models (i.e., translational models). Read More...

October 2021

Web Page

CREx News & Updates October 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGLIGHTS Learn more about services from the CPTR Read More...

September Newsletter 2022 (3)

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September 8, 2022 crex.nih.gov CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Science & Technology Seminars and Training Events Upcoming Seminars and Educational Opportunities The following Read More...

Cooperative Human Tissue Network (CHTN)
Bethesda, MD

Repositories

Trans NIH Facility

The CHTN is a unique NCI-supported resource that provides human tissues and fluids from routine procedures to investigators who utilize human biospecimens in their research. Unlike tissue banks, the CHTN works prospectively with each investigator Read More...

BD Genomics Rhapsody System

Web Page

Total end-to-end system for single-cell research [embed]https://youtu.be/vMzhSzg1rUw[/embed] The BD Rhapsody Single-Cell Analysis system empowers and streamlines your research with a complete system of tools, including reagents and analysis software, Read More...

Chemical Biology Laboratory (CBL): Chemical Synthesis Group
Frederick, MD

Collaborative

The Chemical Synthesis Group is a component of the Chemical Biology Laboratory. This facility provides synthetic chemistry resources and expertise to the NCI Intramural community. The facility’s capabilities include: Providing expertise, consultation, and experience Read More...

Molecular Targets Program (MTP)
Frederick, MD

Collaborative

The Molecular Targets Program (MTP) is an organizational entity within the Center for Cancer Research (CCR) at NCI. The MTP provides the focus and infrastructure to enable CCR tenured and tenure-track Principal Investigators to initiate Read More...

November 2024 Newsletter

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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New NIH Resource Resources Derive Greater Insights and Accelerate your Research Using Bioinformatic Tools! CREx is an NIH Read More...

December 2024 Newsletter

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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New NIH Resource Resources Advance your research with the NIH Mouse Imaging Facility (MIF) The NIH Mouse Imaging Read More...

CCR Volume Electron Microscopy (CVEM)
Frederick, MD

Collaborative

CCR VOLUME Electron Microscopy (CVEM) aims to develop new techniques in volume electron microscopy (vEM) and, in collaboration with CCR Investigators, apply these techniques to research cell biological questions well-suited for study by high-resolution 3D Read More...

BRB Preclinical Biologics Repository
Frederick, MD

Repositories

Trans NIH Facility

The BRB Preclinical Biologics Repository is a central repository that supplies reagents to the broad research community. This NCI-sponsored repository is managed by NCI's Biological Resources Branch (BRB) in the Development Therapeutics Program (DTP) of Read More...

Front page

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Our Mission The Office of Science and Technology Resources (OSTR) catalyzes the advancement of cancer research through making innovative technologies and scientific resources accessible to scientists at the Center for Cancer Research (CCR). OSTR develops Read More...

Statistical Support at ABCS
Frederick, MD

Core Facility

The centrally funded Statistics team within the Advanced Biomedical Computational Science group at the Frederick National Lab provides statistical consultation and data analysis support for NCI laboratories. We have broad-range expertise in biomedically relevant areas Read More...

July 2024 Newsletter

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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx User Survey The CREx Team is carrying out a CREx User Survey. We would greatly appreciate Read More...

June 2021

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CREx News & Updates June 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGHLIGHTS Visit here to learn about services from Read More...

Front page

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Our Mission The Office of Science and Technology Resources (OSTR) catalyzes the advancement of cancer research through making innovative technologies and scientific resources accessible to scientists at the Center for Cancer Research (CCR). OSTR develops Read More...

July 2022 Newsletter

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CREx News & Updates July 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Click below to learn how easy it is to navigate the CREx platform. These short videos will Read More...

August 2024 Newsletter

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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx User Survey The CREx Team is carrying out a CREx User Survey. If you haven’t Read More...

Bioinformatics Resources

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Discover expert help with analysis, processing applications, and licensed software packages.

October Newsletter 2022-2

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October 6, 2022 crex.nih.gov CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Science & Technology Seminars and Training Events Upcoming Seminars and Educational Opportunities The following Read More...

September Newsletter 2022 (2)

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September 8, 2022 crex.nih.gov CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Science & Technology Seminars and Training Events Upcoming Seminars and Educational Opportunities The following Read More...

DTP Natural Products Repository
Frederick, MD

Repositories

Trans NIH Facility

DTP’s Natural Products Repository is the world’s largest storehouse of natural products. It houses close to >200,000 extracts from samples of more than 70,000 plants and >20,000 marine organisms collected from more than 29 countries, plus extracts Read More...

NIH Clinical Center, Center for Cellular Engineering
Bethesda, MD

Core Facility

Trans NIH Facility

The Center of Cellular Engineering (CCE) is a comprehensive facility that develops and manufactures a wide range of cell and gene therapies for early phase clinical trials. The CCE is currently manufacturing chimeric antigen receptor ( Read More...

March 2023 Newsletter

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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New Resources on CREx NCI CLIA Molecular Diagnostics Laboratory (CMDL) The NCI CMDL is available to assist all Read More...

March 2022 Newsletter

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CREx News & Updates March 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight NIA Nonhuman Primate Core The NIA Nonhuman Primate Core supports multi-disciplinary translational aging projects for Read More...

Pediatric Oncology Branch: Behavioral Health Core
Bethesda, MD

Collaborative

The Behavioral Health Core (BHC) is comprised of the two separate but interrelated components: Psychosocial Support and Research Program, and, Health Psychology and Neurobehavioral Research Program., These teams provide specialized expertise, such as patient-reported and Read More...

April 2022 Newsletter

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CREx News & Updates April 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Click below to learn how easy it is to navigate the CREx platform. These short videos will Read More...

September 2024 Newsletter

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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Research Festival The NIH Research Festival highlights the groundbreaking science and the vibrant NIH community driving our Read More...

Xenium Spatial Profiling Technology

Web Page

What is Xenium? Xenium is a high-resolution, imaging-based in situ spatial profiling technology from 10x Genomics that allows for simultaneous expression analysis of RNA targets (currently in range of 100’s) within the same tissue section. Read More...

CCR Electron Microscopy Laboratory (EML)
Frederick, MD

Core Facility

The EML offers investigators access to unique expertise and EM technologies that allow CCR Investigators to explore new avenues of research in order to enhance the knowledge of biological systems. To assist our customers, we Read More...

CCR Collaborative Bioinformatics Resource (CCBR)
Bethesda, MD

Collaborative

The CCR Collaborative Bioinformatics Resource (CCBR) is a centrally funded resource group which provides a mechanism for CCR researchers to obtain many different types of bioinformatics assistance to further their research goals. The group has Read More...

October 2024 Newsletter

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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New NIH Resource Spotlight The NIH Lab Managers Working Group have developed a new NIH-wide database of cold Read More...

August 2021

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CREx News & Updates August 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Collaborative Research Exchange (CREx) News Site Spotlight FACILITY HIGHLIGHTS Learn more about services from the NHLBI Read More...

CCR Genomics Technology Laboratory (GTL)
Frederick, MD

Core Facility

The Genomics Technology Laboratory is an integrated, high-throughput molecular biology laboratory focusing on the development of genetics and genomics technologies, data analysis, and information management tools, in support of CCR Investigators. The laboratory develops integrated Read More...

August 2022 Newsletter

Web Page

CREx News & Updates August 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight NCATS Functional Genomics Laboratory (FGL) FGL is designed to help NIH Investigators use the latest Read More...

Isothermal Titration Calorimetry (ITC) – iTC200

Web Page

Back Services: Biophysics Facility offers ITC calorimeters as open-access instruments.  First-time users must complete a short training session before gaining access to the instrument reservation calendar.  Training includes performing a test experiment and Read More...

Center for Advanced Tissue Imaging (CAT-I)

Web Page

The Center for Advanced Tissue Imaging (CAT-I) is an NIAID and NCI supported effort involving collaborative studies between experts in the Laboratory of Immune System Biology, DIR, NIAID and investigators in the DIR, NIAID and Read More...

January 2022 Newsletter

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CREx News & Updates January 2022 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight NCI ANTIBODY CHARACTERIZATION LABORATORY (ACL) The ACL specializes in rigorously validating antibodies for signaling and Read More...

Pan-Microbial Serology Facility (PMSF)
Bethesda, MD

Collaborative

The Pan-Microbial Serology Facility (PMSF) is part of the Center for Cancer Research (CCR) at the National Cancer Institute (NCI). The PMSF focuses on determining individualized pan-microbial immune profiles associated with human diseases including immunological Read More...

Nanotechnology Characterization Lab
Frederick, MD

Collaborative

NCI established the Nanotechnology Characterization Laboratory (NCL) to support the extramural research community to accelerate the progress of nanomedicine by providing preclinical characterization and safety testing of nanoparticles. It is a collaborative effort between NCI, Read More...

Spatial Biology

Web Page

Employing spatial biology techniques enables acquisition of transcript and protein data from intact tissue sections, and in turn, spatial distribution information and cellular interaction patterns are revealed.

November 2021

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CREx News & Updates November 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight FACILITY HIGLIGHTS Learn more about services from the NINDS Quantitative Magnetic Resonance Imaging Core. NINDS Read More...

Biophysics Core Facility (BCF)

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Biophysics Core Facility assists NIH investigators in measuring molecular interactions and in characterizing macromolecular properties. This includes binding studies of proteins, DNA, RNA, and their ligands in buffers, cell lysate, plasma, and other media. We Read More...

September Newsletter 2022

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September 8, 2022 crex.nih.gov CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight Trans-NIH Intramural Sequencing Center (NISC) NISC is a multi-disciplinary genomics facility that Read More...

NICE-NIH Intramural CryoEM Consortium

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[tabby title="Home"] About NICE-NIH Intramural CryoEM Consortium  NIH Intramural CryoEM Consortium (NICE) serves intramural investigators in all NIH IC’s. NICE provides access to state-of-the-art Titan Krios cryo-electron microscopes for atomic-resolution structure determination of Read More...

 NIH Collaborative Research Exchange (CREx)

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The NIH Intramural Research Program Collaborative Research Exchange (CREx) The Collaborative Research Exchange (CREx) is an online CCR marketplace where investigators can search, browse, and request information for research services, technologies, or custom products (antibody Read More...

Mass Spectrometry for Proteins

Web Page

Mass Spectrometry Section of the Collaborative Protein Technology Resource (Bldg. 37) Core Capabilities: Identification of proteins in complexes, organelles, subcellular fractions, or fluids. Global relative protein quantitation. Quantitation by isotopic labeling of cells in culture (SILAC) Read More...

NHLBI Murine Phenotyping Core
Bethesda, MD

Core Facility

The NHLBI Murine Phenotyping Core carries out physiologic and behavioral testing in a diversity of mouse models for NHLBI and other NIH institutes. Established Technologies: Cardiovascular Phenotyping, Metabolic Phenotyping, Pulmonary Phenotyping, Behavioral Phenotyping, Exercise Physiology, Read More...

Office of Collaborative Biostatistics
Bethesda, MD

Collaborative

The Office of Collaborative Biostatistics, Office of the Clinical Director, is the statistical and data management component of CCR. The Section provides statistical leadership and data management consultation for CCR’s major clinical activities and Read More...

Differential Scanning Calorimetry (DSC) – Microcal VP-DSC

Web Page

Back Services: Biophysics Facility offers DSC as an open-access instrument. First-time users must complete training before gaining access to the instrument reservation calendar. Location: Building 50, room 3123 Description: The differential scanning calorimeter measures the constant pressure Read More...

CHTN Mid-Atlantic Division (University of Virginia)
Charlottesville, VA

Repositories

Trans NIH Facility

The Mid-Atlantic CHTN is one of six participating divisions of the Cooperative Human Tissue Network (CHTN) and is based in the Pathology Department at the University of Virginia. While primarily a resource for cancer researchers, Read More...

Visium Spatial Gene Expression Technology

Web Page

What is Visium FFPE v2 with CytAssist? Visium FFPE v2 is sequencing-based spatial profiling technology developed by 10x Genomics. This assay can take mouse or human tissue sections on normal glass slides as input and Read More...

March 2024 Newsletter

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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Intramural CryoEM (NICE) Consortium NICE provides NCI, NIAID, NIEHS, NICHD, NIDCR, NEI, and NIA investigators with Read More...

April 2024 Newsletter

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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Extramural Common Fund Resources Metabolomics Workbench Developed by the NIH Metabolomics Common Fund's National Metabolomics Data Repository ( Read More...

STARS Request

Web Page

Supplemental Technology Award Review System (STARS) Overview STARS Request Form STARS System The Supplemental Technology Award Review System (STARS) is a web-based interface for submission and review of S&S supplement requests by CCR Read More...

May 2024 Newsletter

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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Intramural Core Resources NHGRI Flow Cytometry Core The Core performs high quality single cell analysis through the Read More...

December 2021

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CREx News & Updates December 2021 Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Site Spotlight FACILITY HIGLIGHTS Learn more about services from the STRIDES Initiative. VIEW STRIDES INITIATIVE NIH Cores Read More...

Molecular Pathology Unit
Bethesda, Maryland

Collaborative

The Molecular Pathology Unit is intended to spearhead opportunities for bridging basic and clinical research efforts by more precisely optimizing the development, characterization, and utilization of models of human disease. The initiative approach includes both Read More...

Fluorescence – PTI/Horiba QuantaMaster

Web Page

Back Services: Biophysics Facility offers fluorometers as open-access instruments.  First-time users must complete a short training session before gaining access to the instrument reservation calendar. Location: Building 50, room 3226 Description: Some substances reemit light after Read More...

June 2024 Newsletter

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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More New CREx Program Manager The CREx Team is happy to announce Deepika Velampati as the new CREx Program Read More...

NIH AgingResearchBiobank
Bethesda, Maryland

Core Facility

Repositories

The AgingResearchBiobank was officially launched in January 2019 with a mission to provide a state-of-the-art inventory system for the storage, maintenance, and distribution of de-identified biospecimens and associated phenotypic, clinical, and imaging data from numerous NIA-funded Read More...

CLIA Molecular Diagnostics Laboratory (CMDL)

Web Page

The CLIA Molecular Diagnostics Laboratory (CMDL) provides an array of services for groups at the NIH Clinical Center, Fort Detrick, and Hood College, among others. They support cancer- and disease-related research by making Read More...

Protein Characterization Laboratory

Web Page

Protein Characterization Laboratory (PCL) offers various technologies to CCR investigators to characterize proteins and metabolites. The laboratory develops and applies state-of-the-art analytical technologies, primarily mass spectrometry, liquid chromatography, and Surface Plasmon Resonance (SPR), to advance Read More...

May 2023 Newsletter

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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More Technology Event Biophysical Methods for Protein Interactions Monday, May 15 – Friday, May 19, 2023 This workshop will review the strategies of Read More...

July 2023 Newsletter

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CREx Monthly Newsletter Learn about the NIH Collaborative Research Exchange (CREx), Core Facilities, Webinars, & More NIH Cores on CREx NIBIB BEPS Micro Analytical Immunochemistry Unit The Micro Analytical Immunochemistry Unit employs a variety Read More...

CCR Intravital Microscopy Core

Web Page

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Center for Structural Biology: Biophysics Resource
Frederick, MD

Core Facility

The Biophysics Resource (BR) was established in January 2001. Our mission is to provide CCR investigators with access to both the latest instrumentation and expertise in characterizing the biophysical aspects of systems under structural investigation. The Read More...

CCR Radiation Oncology Branch Bioinformatics Core
Bethesda, Maryland

Collaborative

Radiation Oncology Branch is part of CCR. Bioinformatics core is a collaborative resource to support ROB branch and provide service to ROB investigators from NCI and other Institutes access to new technologies, bioinformatics, statistical analysis Read More...

Protein Expression Laboratory

Web Page

Protein Expression Laboratory The Protein Expression Laboratory develops, improves, and delivers protein-centric services. Our goal is to help client investigators achieve their research goals with the lowest possible cost in the shortest time. All PEL Read More...

Genomics Technology Laboratory

Web Page

The Genomics Laboratory (formerly Laboratory of Molecular Technology) is an integrated, high-throughput molecular biology laboratory focusing on the development of genetics and genomics technologies, together with associated laboratory automation systems, data analysis, and information management Read More...

Biophysics Core Technologies

Web Page

Home About the Biophysics Core Biophysics Core Services [tabby title="Instrumentation"] NHLBI Biophysics Core The Biophysics Core Facility: Overview Core Facilities provide scientific resources, cutting-edge technologies and novel approaches to support DIR scientists. Availability of Read More...

Multi-Angle Light Scattering (MALS)

Web Page

Back Services: We offer a limited sample processing service using standard SEC-MALS and FFF protocols.  This service is intended for the occasional users of this system.  Researchers who expect to use this instrument Read More...

NHLBI Biophysics Core
Bethesda, MD

Core Facility

The Biophysics Core’s mission is to provide support in the study of macromolecular interactions, dynamics, and stability by offering consultations, training, professional collaborations, and instrument access. General Services: Multi-technique molecular interaction studies, Kinetic and Read More...

NCATS Functional Genomics Laboratory
Rockville, MD

Core Facility

Trans NIH Facility

The Functional Genomics Laboratory (formerly, the RNAi Screening Facility) of the National Center for Advancing Translational Sciences (NCATS) assist investigators with all stages of project planning and execution, beginning with assay development through genome-wide siRNA Read More...

Chemistry and Synthesis Center
Rockville, MD

Trans NIH Facility

The Chemistry and Synthesis Center (CSC) of the National Heart, Lung, and Blood Institute (NHLBI) provides IRP scientists with targeted imaging probes and chemical tools that help accelerate cell-based assays, in vivo imaging studies, and Read More...

Microfluidic Diffusion Sizing (MDS) - Fluidity One-M

Web Page

Back Services: Biophysics Facility offers MDS as an open-access instrument. First-time users must complete a short training session before gaining access to the instrument reservation calendar. Training includes the KD determination of a standard molecular Read More...

Technology Video Library

Web Page

The OSTR offers cutting-edge technology platforms to the CCR scientific community through centralized facilities. The videos accessed through this page are designed to introduce the various scientific methodologies OSTR makes available through the cores on Read More...

Bio-Layer Interferometry (BLI) - Octet RED96

Web Page

Back Services: Biophysics Facility offers Octet as an open-access instrument.  First-time users must complete a short training session before gaining access to the instrument reservation calendar.  Training includes a full analysis of a Read More...

Policies

Web Page

Confocal

General Usage Policies Principal investigators should read this document and sign it. PI’s/postdocs should attach a short-written summary of the project to the signed doc. If the project changes, Read More...

BTEP Video Archive of Past Classes

Web Page

Bioinformatics

Listed below are the video recordings of past BTEP events (classes, seminars, workshops). Videos are hosted on various servers and may play slightly differently. Some videos may be downloaded for local viewing. Recorded Videos of Read More...

Research

Web Page

CRTP

No summary available.